Measuring symptoms in the irritable bowel syndrome: development of a framework for clinical trials von Spiegel, B. M. R., Bolus, R., Agarwal, N., Sayuk, G., Harris, L. A., Lucak, S., Esrailian, E., Chey, W. D., Lembo, A., Karsan, H., Tillisch, K., Talley, J., Chang, L.

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Measuring irritable bowel syndrome patient‐reported outcomes with an abdominal pain numeric rating scale von SPIEGEL, B., BOLUS, R., HARRIS, L. A., LUCAK, S., NALIBOFF, B., ESRAILIAN, E., CHEY, W. D., LEMBO, A., KARSAN, H., TILLISCH, K., TALLEY, J., MAYER, E., CHANG, L.

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Characterizing abdominal pain in IBS: guidance for study inclusion criteria, outcome measurement and clinical practice von Spiegel, B. M. R., Bolus, R., Harris, L. A., Lucak, S., Chey, W. D., Sayuk, G., Esrailian, E., Lembo, A., Karsan, H., Tillisch, K., Talley, J., Chang, L.

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Endoscopic screening for esophageal varices in cirrhosis: Is it ever cost effective? von Spiegel, Brennan M.R., Targownik, Laura, Dulai, Gareth S., Karsan, Hetal A., Gralnek, Ian M.

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Measuring IBS patient reported outcomes with an abdominal pain numeric rating scale: results from the proof cohort von SPIEGEL, B., BOLUS, R., HARRIS, L. A., LUCAK, S., NALIBOFF, B., ESRAILIAN, E., CHEY, W. D., LEMBO, A., KARSAN, H., TILLISCH, K., TALLEY, J., MAYER, E., CHANG, L.

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Combination endoscopic band ligation and sclerotherapy compared with endoscopic band ligation alone for the secondary prophylaxis of esophageal variceal hemorrhage : A meta-analysi... von KARSAN, Hetal A, MORTON, Sally C, SHEKELLE, Paul G, SPIEGEL, Brennan M. R, SUTTORP, Marika J, EDELSTEIN, Marc A, GRALNEK, Ian M

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Detection of urban heat island in Istanbul, Turkey von KARACA, M, ANTEPLIOGLU, Ü, KARSAN, H

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Vascularization predicts overall survival and risk of transformation in follicular lymphoma von FARINHA, Pedro, KYLE, Alastair H, MINCHINTON, Andrew I, CONNORS, Joseph M, KARSAN, Aly, GASCOYNE, Randy D

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Single-cell profiling reveals a memory B cell-like subtype of follicular lymphoma with increased transformation risk von Wang, Xuehai, Nissen, Michael, Gracias, Deanne, Kusakabe, Manabu, Simkin, Guillermo, Jiang, Aixiang, Duns, Gerben, Sarkozy, Clementine, Hilton, Laura, Chavez, Elizabeth A., Segat, Gabriela C., Wong, Rachel, Kim, Jubin, Aoki, Tomohiro, Islam, Rashedul, May, Christina, Hung, Stacy, Tyshchenko, Kate, Brinkman, Ryan R., Hirst, Martin, Karsan, Aly, Freeman, Ciara, Sehn, Laurie H., Morin, Ryan D., Roth, Andrew J., Savage, Kerry J., Craig, Jeffrey W., Shah, Sohrab P., Steidl, Christian, Scott, David W., Weng, Andrew P.

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SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS von Malcovati, Luca, Stevenson, Kristen, Papaemmanuil, Elli, Neuberg, Donna, Bejar, Rafael, Boultwood, Jacqueline, Bowen, David T., Campbell, Peter J., Ebert, Benjamin L., Fenaux, Pierre, Haferlach, Torsten, Heuser, Michael, Jansen, Joop H., Komrokji, Rami S., Maciejewski, Jaroslaw P., Walter, Matthew J., Fontenay, Michaela, Garcia-Manero, Guillermo, Graubert, Timothy A., Karsan, Aly, Meggendorfer, Manja, Pellagatti, Andrea, Sallman, David A., Savona, Michael R., Sekeres, Mikkael A., Steensma, David P., Tauro, Sudhir, Thol, Felicitas, Vyas, Paresh, Van de Loosdrecht, Arjan A., Haase, Detlef, Tüchler, Heinz, Greenberg, Peter L., Ogawa, Seishi, Hellstrom-Lindberg, Eva, Cazzola, Mario

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High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations von Hui, Tony, Cao, Qi, Wegrzyn-Woltosz, Joanna, O'Neill, Kieran, Hammond, Colin A., Knapp, David J.H.F., Laks, Emma, Moksa, Michelle, Aparicio, Samuel, Eaves, Connie J., Karsan, Aly, Hirst, Martin

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The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery von Adams, David, Altucci, Lucia, Amit, Ido, Aparicio, Samuel, Arima, Takahiro, Asnafi, Vahid, Bae, Jae-Bum, Bassler, Kevin, Bilenky, Mikhail, Boehm, Bernhard, Bourque, Guillaume, Brors, Benedikt, Bussemakers, Marion J., Chadwick, Lisa, Chen, Wei, Cheung, Tom H., Choi, Nak Hyen, Chung, Ho-Ryun, Clarke, Laura, Dermitzakis, Manolis, Dylag, Tomasz, Eaves, Connie J., Ebert, Peter, Eils, Jürgen, Enver, Tariq, Ferguson-Smith, Anne, Fitzgibbon, Jude, Flicek, Paul, Fraser, Peter, Gasparoni, Nina, Gasparoni, Gilles, Heath, Simon, Helin, Kristian, Hitz, Benjamin C., Horsthemke, Bernhard, Ip, Nancy Y., Ito, Takashi, Jenuwein, Thomas, Joly, Yann, Kanai, Yae, Kang, Hee Gyung, Kiemer, Alexandra K., Kim, Song Cheol, Kim, Bong-Jo, Lehrach, Hans, Leitão, Elsa, Lengauer, Thomas, Lernmark, Åke, Leung, Gilberto K.K., Leung, Danny, Ma, Yussanne, Martin-Subero, Jose Ignacio, Maschke, Karen, Merten, Christoph, Minucci, Saverio, Mitsuyama, Totai, Moore, Richard A., Nordström, Karl, Norstedt, Irene, Ouellette, Francis, Pap, Thomas, Pelicci, Pier Giuseppe, Phillips, Anthony G., Polansky, Julia, Pospisilik, J. Andrew, Prabhakar, Shyam, Procaccini, Dena C., Radbruch, Andreas, Rajewsky, Nikolaus, Rakyan, Vardham, Richardson, David, Rothstein, Mark, Sasaki, Hiroyuki, Sauer, Sascha, Schmidt, Florian, Schultze, Joachim L., Schulyer, Ronald P., Schulz, Marcel, Siebert, Reiner, Sinha, Anupam, Soranzo, Nicole, Spivakov, Mikhail, Steidl, Christian, Suzuki, Narumi, Torrents, David, Tyson, Frederick L., Ullrich, Sebastian, Ushijima, Toshikazu, Valencia, Alfonso, Wallace, Chris, Weber, Stephanie, Weiler, Nina, Weng, Andrew, Wilder, Steven, Yamashita, Yasuhiro, Yap, Desmond Y., Yip, Kevin Y., Yip, Stephen, Zerbino, Daniel, Zipprich, Gideon

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Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling von Chang, Linda, Noseda, Michela, Higginson, Michelle, Ly, Michelle, Patenaude, Alexandre, Fuller, Megan, Kyle, Alastair H, Minchinton, Andrew I, Puri, Mira C, Dumont, Daniel J, Karsan, Aly

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Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice von Grants, Jennifer M., Wegrzyn, Joanna, Hui, Tony, O'Neill, Kieran, Shadbolt, Marion, Knapp, David J.H.F., Parker, Jeremy, Deng, Yu, Gopal, Aparna, Docking, T. Roderick, Fuller, Megan, Li, Jenny, Boldin, Mark, Eaves, Connie J., Hirst, Martin, Karsan, Aly

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Loss of the Notch effector RBPJ promotes tumorigenesis von Kulic, Iva, Robertson, Gordon, Chang, Linda, Baker, Jennifer H E, Lockwood, William W, Mok, Winnie, Fuller, Megan, Fournier, Michèle, Wong, Nelson, Chou, Vennie, Robinson, Mark D, Chun, Hye-Jung, Gilks, Blake, Kempkes, Bettina, Thomson, Thomas A, Hirst, Martin, Minchinton, Andrew I, Lam, Wan L, Jones, Steven, Marra, Marco, Karsan, Aly

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Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling von Coulombe, Patrick, Paliouras, Grigorios N., Clayton, Ashley, Hussainkhel, Angela, Fuller, Megan, Jovanovic, Vida, Dauphinee, Shauna, Umlandt, Patricia, Xiang, Ping, Kyle, Alistair H., Minchinton, Andrew I., Humphries, R. Keith, Hoodless, Pamela A., Parker, Jeremy D.K., Wright, Joanne L., Karsan, Aly

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HPR129 Real-World Policy Effects of Implementing Multi-Gene Panel Sequencing for Advanced Cancers in British Columbia, Canada: An Interrupted Time Series Analysis von Weymann, D, Krebs, E, Pollard, S, Bosdet, I, Yip, S, Karsan, A, Ho, C, Lim, H, Loree, JM, Laskin, J, Law, M, Regier, DA

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PT30 Real-World Cost-Effectiveness of Publicly Reimbursed Multi-Gene Panel Sequencing to Inform Therapeutic Decisions for Advanced Non-Small Cell Lung Cancer in British Columbia, C... von Krebs, E, Weymann, D, Ho, C, Bosdet, I, Laskin, J, Lim, H, Yip, S, Karsan, A, Hanna, T, Pollard, S, Regier, DA

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Canadian Anaplastic Lymphoma Kinase Study: A Model for Multicenter Standardization and Optimization of ALK Testing in Lung Cancer von Cutz, Jean-Claude, Craddock, Kenneth J., Torlakovic, Emina, Brandao, Guilherme, Carter, Ronald F., Bigras, Gilbert, Deschenes, Jean, Izevbaye, Iyare, Xu, Zhaolin, Greer, Wenda, Yatabe, Yasushi, Ionescu, Diana, Karsan, Aly, Jung, Sungmi, Fraser, Richard S., Blumenkrantz, Miriam, Lavoie, Josee, Fortin, Flechere, Bojarski, Anna, Côté, Gilbert B., van den Berghe, Janette A., Rashid-Kolvear, Fariborz, Trotter, Martin, Sekhon, Harmanjatinder S., Albadine, Roula, Tran-Thanh, Danh, Gorska, Isabelle, Knoll, Joan H.M., Xu, Jie, Blencowe, Ben, Iafrate, A. John, Hwang, David M., Pintilie, Melania, Gaspo, Rania, Couture, Christian, Tsao, Ming-Sound

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Relapse Timing Is Associated With Distinct Evolutionary Dynamics in Diffuse Large B-Cell Lymphoma von Hilton, Laura K, Ngu, Henry S, Collinge, Brett, Dreval, Kostiantyn, Ben-Neriah, Susana, Rushton, Christopher K, Wong, Jasper C H, Cruz, Manuela, Roth, Andrew, Boyle, Merrill, Meissner, Barbara, Slack, Graham W, Farinha, Pedro, Craig, Jeffrey W, Gerrie, Alina S, Freeman, Ciara L, Villa, Diego, Rodrigo, Judith A, Song, Kevin, Crump, Michael, Shepherd, Lois, Hay, Annette E, Kuruvilla, John, Savage, Kerry J, Kridel, Robert, Karsan, Aly, Marra, Marco A, Sehn, Laurie H, Steidl, Christian, Morin, Ryan D, Scott, David W

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