Structure, function and pharmacology of human itch GPCRs von Cao, Can, Kang, Hye Jin, Singh, Isha, Chen, He, Zhang, Chengwei, Ye, Wenlei, Hayes, Byron W., Liu, Jing, Gumpper, Ryan H., Bender, Brian J., Slocum, Samuel T., Krumm, Brian E., Lansu, Katherine, McCorvy, John D., Kroeze, Wesley K., English, Justin G., DiBerto, Jeffrey F., Olsen, Reid H. J., Huang, Xi-Ping, Zhang, Shicheng, Liu, Yongfeng, Kim, Kuglae, Karpiak, Joel, Jan, Lily Y., Abraham, Soman N., Jin, Jian, Shoichet, Brian K., Fay, Jonathan F., Roth, Bryan L.

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Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65 von Huang, Xi-Ping, Karpiak, Joel, Kroeze, Wesley K., Zhu, Hu, Chen, Xin, Moy, Sheryl S., Saddoris, Kara A., Nikolova, Viktoriya D., Farrell, Martilias S., Wang, Sheng, Mangano, Thomas J., Deshpande, Deepak A., Jiang, Alice, Penn, Raymond B., Jin, Jian, Koller, Beverly H., Kenakin, Terry, Shoichet, Brian K., Roth, Bryan L.

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Structure-based ligand discovery for the protein–protein interface of chemokine receptor CXCR4 von Mysinger, Michael M, Weiss, Dahlia R, Ziarek, Joshua J, Gravel, Stéphanie, Doak, Allison K, Karpiak, Joel, Heveker, Nikolaus, Shoichet, Brian K, Volkman, Brian F

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Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes von Salas-Sarduy, Emir, Landaburu, Lionel Urán, Karpiak, Joel, Madauss, Kevin P., Cazzulo, Juan José, Agüero, Fernán, Alvarez, Vanina Eder

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Actin Is Required for IFT Regulation in Chlamydomonas reinhardtii von Avasthi, Prachee, Onishi, Masayuki, Karpiak, Joel, Yamamoto, Ryosuke, Mackinder, Luke, Jonikas, Martin C., Sale, Winfield S., Shoichet, Brian, Pringle, John R., Marshall, Wallace F.

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Quantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognition von Melero, Cristina, Ollikainen, Noah, Harwood, Ian, Karpiak, Joel, Kortemme, Tanja

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Structural basis of G protein–coupled receptor–G protein interactions von Hu, Jianxin, Wess, Jürgen, Wang, Yan, Zhang, Xiaohong, Lloyd, John R, Li, Jian Hua, Karpiak, Joel, Costanzi, Stefano

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In silico design of novel probes for the atypical opioid receptor MRGPRX2 von Lansu, Katherine, Karpiak, Joel, Liu, Jing, Huang, Xi-Ping, McCorvy, John D, Kroeze, Wesley K, Che, Tao, Nagase, Hiroshi, Carroll, Frank I, Jin, Jian, Shoichet, Brian K, Roth, Bryan L

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Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs von McCorvy, John D, Butler, Kyle V, Kelly, Brendan, Rechsteiner, Katie, Karpiak, Joel, Betz, Robin M, Kormos, Bethany L, Shoichet, Brian K, Dror, Ron O, Jin, Jian, Roth, Bryan L

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Ligand and structure-based models for the prediction of ligand-receptor affinities and virtual screenings: Development and application to the β₂-adrenergic receptor von Vilar, Santiago, Karpiak, Joel, Costanzi, Stefano

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Ligand and structure-based models for the prediction of ligand-receptor affinities and virtual screenings: Development and application to the beta(2)-adrenergic receptor von Vilar, Santiago, Karpiak, Joel, Costanzi, Stefano

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Selectivity Challenges in Docking Screens for GPCR Targets and Antitargets von Weiss, Dahlia R, Karpiak, Joel, Huang, Xi-Ping, Sassano, Maria F, Lyu, Jiankun, Roth, Bryan L, Shoichet, Brian K

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Small-Molecule Allosteric Modulators of the Protein Kinase PDK1 from Structure-Based Docking von Rettenmaier, T. Justin, Fan, Hao, Karpiak, Joel, Doak, Allison, Sali, Andrej, Shoichet, Brian K, Wells, James A

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In silico analysis of the binding of agonists and blockers to the β2-adrenergic receptor von Vilar, Santiago, Karpiak, Joel, Berk, Barkin, Costanzi, Stefano

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Design, Synthesis, Crystal Structures, and Antimicrobial Activity of Sulfonamide Boronic Acids as β-Lactamase Inhibitors von Eidam, Oliv, Romagnoli, Chiara, Caselli, Emilia, Babaoglu, Kerim, Pohlhaus, Denise Teotico, Karpiak, Joel, Bonnet, Richard, Shoichet, Brian K, Prati, Fabio

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Author Correction: Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes von Salas-Sarduy, Emir, Landaburu, Lionel Urán, Karpiak, Joel, Madauss, Kevin P., Cazzulo, Juan José, Agüero, Fernán, Alvarez, Vanina Eder

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Structure-inspired design of [beta]-arrestin-biased ligands for aminergic GPCRs von Mccorvy, John D, Butler, Kyle V, Kelly, Brendan, Rechsteiner, Katie, Karpiak, Joel, Betz, Robin M, Kormos, Bethany L, Shoichet, Brian K, Dror, Ron O, Jin, Jian, Roth, Bryan L

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Ligand and structure‐based models for the prediction of ligand‐receptor affinities and virtual screenings: Development and application to the β 2 ‐adrenergic receptor von Vilar, Santiago, Karpiak, Joel, Costanzi, Stefano

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Ligand and structure-based models for the prediction of ligand-receptor affinities and virtual screenings: Development and application to the ^sub [beta]2^-adrenergic receptor von Vilar, Santiago, Karpiak, Joel, Costanzi, Stefano

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Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation von Rutkowska, Anna, Eberl, H Christian, Werner, Thilo, Hennrich, Marco L, Sévin, Daniel C, Petretich, Massimo, Reddington, James P, Pocha, Shirin, Gade, Stephan, Martinez-Segura, Amalia, Dvornikov, Dmytro, Karpiak, Joel, Sweetman, Gavain M A, Fufezan, Christian, Duempelfeld, Birgit, Braun, Florian, Schofield, Christopher, Keles, Hakan, Alvarado, David, Wang, Zhuo, Jansson, Keith H, Faelth-Savitski, Maria, Curry, Edward, Remlinger, Katja, Stronach, Euan A, Feng, Bin, Sharma, Geeta, Coleman, Kevin, Grandi, Paola, Bantscheff, Marcus, Bergamini, Giovanna

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