Microfluidic sorting of mammalian cells by optical force switching von Wang, Mark M, Tu, Eugene, Raymond, Daniel E, Yang, Joon Mo, Zhang, Haichuan, Hagen, Norbert, Dees, Bob, Mercer, Elinore M, Forster, Anita H, Kariv, Ilona, Marchand, Philippe J, Butler, William F

Volltext

Effect of cryopreservation on delineation of immune cell subpopulations in tumor specimens as determined by multiparametric single cell mass cytometry analysis von Kadić, Elma, Moniz, Raymond J., Huo, Ying, Chi, An, Kariv, Ilona

Volltext

Development of a High Throughput Equilibrium Dialysis Method von Kariv, Ilona, Cao, Hong, Oldenburg, Kevin R.

Volltext

An orally available non-nucleotide STING agonist with antitumor activity von Pan, Bo-Sheng, Perera, Samanthi A, Piesvaux, Jennifer A, Presland, Jeremy P, Schroeder, Gottfried K, Cumming, Jared N, Trotter, B Wesley, Altman, Michael D, Buevich, Alexei V, Cash, Brandon, Cemerski, Saso, Chang, Wonsuk, Chen, Yiping, Dandliker, Peter J, Feng, Guo, Haidle, Andrew, Henderson, Timothy, Jewell, James, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny, Lacey, Brian M, Laskey, Jason, Lesburg, Charles A, Liang, Rui, Long, Brian J, Lu, Min, Ma, Yanhong, Minnihan, Ellen C, O'Donnell, Greg, Otte, Ryan, Price, Laura, Rakhilina, Larissa, Sauvagnat, Berengere, Sharma, Sharad, Tyagarajan, Sriram, Woo, Hyun, Wyss, Daniel F, Xu, Serena, Bennett, David Jonathan, Addona, George H

Volltext

Development of High-Throughput TR-FRET and AlphaScreen® Assays for Identification of Potent Inhibitors of PDK1 von Xu, Zangwei, Nagashima, Kumiko, Sun, Dongyu, Rush, Thomas, Northrup, Alan, Andersen, Jannik N., Kariv, Ilona, Bobkova, Ekaterina V.

Volltext

Advances in high-dimensional mass cytometry cell and tissue analyses for translational biomarker discovery von Kadic, Elma, Kariv, Ilona

Volltext

Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer von Chang, Wonsuk, Altman, Michael D, Lesburg, Charles A, Perera, Samanthi A, Piesvaux, Jennifer A, Schroeder, Gottfried K, Wyss, Daniel F, Cemerski, Saso, Chen, Yiping, DiNunzio, Edward, Haidle, Andrew M, Ho, Thu, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny E, Lacey, Brian M, Laskey, Jason, Lim, Jongwon, Long, Brian J, Ma, Yanhong, Maddess, Matthew L, Pan, Bo-Sheng, Presland, Jeremy P, Spooner, Edward, Steinhuebel, Dietrich, Truong, Quang, Zhang, Zhibo, Fu, Jianmin, Addona, George H, Northrup, Alan B, Parmee, Emma, Tata, James R, Bennett, David Jonathan, Cumming, Jared N, Siu, Tony, Trotter, B. Wesley

Volltext

High-Throughput Analysis of HGF-Stimulated Cell Scattering von Chan, Grace K.Y., Lutterbach, Bart A., Pan, Bo-Sheng, Kariv, Ilona, Szewczak, Alexander A.

Volltext

Determination of EPAC2 function using EPAC2 null Min6 sublines generated through CRISPR-Cas9 technology von Xu, Haiyan, Yang, Yi, Chen, Yiping, Mueller, Uwe, Iyer, Sharanya, Presland, Jeremy, Yang, Ruojing, Kariv, Ilona

Volltext

Effect of cryopreservation on delineation of immune cell subpopulations in tumor specimens as determinated by multiparametric single cell mass cytometry analysis von Kadić, Elma, Moniz, Raymond J, Huo, Ying, Chi, An, Kariv, Ilona

Volltext

Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor von Elwood, Fiona, Witter, David J., Piesvaux, Jennifer, Kraybill, Brian, Bays, Nathan, Alpert, Carla, Goldenblatt, Peter, Qu, Yujie, Ivanovska, Irena, Lee, Hyun-Hee, Chiu, Chi-Sung, Tang, Hao, Scott, Mark E., Deshmukh, Sujal V., Zielstorff, Mark, Byford, Alan, Chakravarthy, Kalyan, Dorosh, Lauren, Rivkin, Alexey, Klappenbach, Joel, Pan, Bo-Sheng, Kariv, Ilona, Dinsmore, Christopher, Slipetz, Deborah, Dandliker, Peter J.

Volltext

Abstract LB-029: Identification of predictive genetic signatures of Cytarabine responsiveness in acute myeloid leukemia using a novel 3D translational culture model of primary bone... von Xu, Haiyan, Muise, Eric S., Javaid, Sarah, Chen, Lan, Cristescu, Razvan, Mansueto, My Sam, Follmer, Nicole, Cho, Jennifer, Kerr, Kimberley, Altura, Rachel, Machacek, Michelle, Nicholson, Benjamin, Addona, George, Kariv, Ilona, Chen, Hongmin

Volltext

Design and Implementation of an Automated Compound Management System in Support of Lead Optimization von Quintero, Catherine, Kariv, Ilona

Volltext

Miniaturization of a Mammalian Cell-Based Assay: Luciferase Reporter Gene Readout in a 3 Microliter 1536-Well Plate von Maffia, Anthony M., Kariv, Ilona, Oldenburg, Kevin R.

Volltext

Identification of predictive genetic signatures of Cytarabine responsiveness using a 3D acute myeloid leukaemia model von Xu, Haiyan, Muise, Eric S., Javaid, Sarah, Chen, Lan, Cristescu, Razvan, Mansueto, My Sam, Follmer, Nicole, Cho, Jennifer, Kerr, Kimberley, Altura, Rachel, Machacek, Michelle, Nicholson, Benjamin, Addona, George, Kariv, Ilona, Chen, Hongmin

Volltext

Establishing and Validating Cellular Functional Target Engagement Assay for Selective IRAK4 Inhibitor Discovery von Chen, Yiping, Sun, Dongyu, Yang, Ruojing, Lim, Jongwon, Sondey, Christopher, Presland, Jeremy, Rakhilina, Larissa, Addona, George, Kariv, Ilona, Chen, Hongmin

Volltext

Discovery of PDK1 Kinase Inhibitors with a Novel Mechanism of Action by Ultrahigh Throughput Screening von Bobkova, Ekaterina V., Weber, Michael J., Xu, Zangwei, Zhang, Yan-Ling, Jung, Joon, Blume-Jensen, Peter, Northrup, Alan, Kunapuli, Priya, Andersen, Jannik N., Kariv, Ilona

Volltext

Development of High-Throughput Assays for Evaluation of Hematopoietic Progenitor Kinase 1 Inhibitors von Lacey, Brian M., Xu, Zangwei, Chai, Xiaomei, Laskey, Jason, Fradera, Xavier, Mittal, Payal, Mishra, Sasmita, Piesvaux, Jennifer, Saradjian, Peter, Shaffer, Lynsey, Vassileva, Galya, Gerdt, Catherine, Wang, Yun, Ferguson, Heidi, Smith, Dustin M., Ballard, Jeanine, Wells, Steven, Jain, Rishabh, Mueller, Uwe, Addona, George, Kariv, Ilona, Methot, Joey L., Bittinger, Mark, Ranganath, Sheila, Mcleod, Robbie, Pasternak, Alexander, Miller, J. Richard, Xu, Haiyan

Volltext

Integration of Affinity Selection–Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway von Kutilek, Victoria D., Andrews, Christine L., Richards, Matthew P., Xu, Zangwei, Sun, Tianxiao, Chen, Yiping, Hashke, Andrew, Smotrov, Nadya, Fernandez, Rafael, Nickbarg, Elliott B., Chamberlin, Chad, Sauvagnat, Berengere, Curran, Patrick J., Boinay, Ryan, Saradjian, Peter, Allen, Samantha J., Byrne, Noel, Elsen, Nathaniel L., Ford, Rachael E., Hall, Dawn L., Kornienko, Maria, Rickert, Keith W., Sharma, Sujata, Shipman, Jennifer M., Lumb, Kevin J., Coleman, Kevin, Dandliker, Peter J., Kariv, Ilona, Beutel, Bruce

Volltext

High Throughput Quantitation of cAMP Production Mediated by Activation of Seven Transmembrane Domain Receptors von Kariv, Ilona, Stevens, Michelle E., Behrens, Davette L., Oldenburg, Kevin R.

Volltext