The Where, the When, and the How of Immune Monitoring for Cancer Immunotherapies in the Era of Checkpoint Inhibition von Hegde, Priti S, Karanikas, Vaios, Evers, Stefan

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CD25 targeting with the afucosylated human IgG1 antibody RG6292 eliminates regulatory T cells and CD25+ blasts in acute myeloid leukemia von Pousse, Laurène, Korfi, Koorosh, Medeiros, Bruno C, Berrera, Marco, Kumpesa, Nadine, Eckmann, Jan, Hutter, Idil Karakoc, Griesser, Vera, Karanikas, Vaios, Klein, Christian, Amann, Maria

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Foxp3 expression in human cancer cells von Karanikas, Vaios, Speletas, Matthaios, Zamanakou, Maria, Kalala, Fani, Loules, Gedeon, Kerenidi, Theodora, Barda, Angeliki K, Gourgoulianis, Konstantinos I, Germenis, Anastasios E

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Phase 1, first-in-human study of TYRP1-TCB (RO7293583), a novel TYRP1-targeting CD3 T-cell engager, in metastatic melanoma: active drug monitoring to assess the impact of immune re... von Spreafico, Anna, Couselo, Eva Muñoz, Irmisch, Anja, Bessa, Juliana, Au-Yeung, George, Bechter, Oliver, Svane, Inge Marie, Sanmamed, Miguel F, Gambardella, Valentina, McKean, Meredith, Callahan, Margaret, Dummer, Reinhard, Klein, Christian, Umaña, Pablo, Justies, Nicole, Heil, Florian, Fahrni, Linda, Opolka-Hoffmann, Eugenia, Waldhauer, Inja, Bleul, Conrad, Staack, Roland F, Karanikas, Vaios, Fowler, Stephen

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Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer von Trüb, Marta, Uhlenbrock, Franziska, Claus, Christina, Herzig, Petra, Thelen, Martin, Karanikas, Vaios, Bacac, Marina, Amann, Maria, Albrecht, Rosemarie, Ferrara-Koller, Claudia, Thommen, Daniela, Rothschield, Sacha, Savic Prince, Spasenija, Mertz, Kirsten D, Cathomas, Gieri, Rosenberg, Robert, Heinzelmann-Schwarz, Viola, Wiese, Mark, Lardinois, Didier, Umana, Pablo, Klein, Christian, Laubli, Heinz, Kashyap, Abhishek S, Zippelius, Alfred

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A Monoclonal Cytolytic T-Lymphocyte Response Observed in a Melanoma Patient Vaccinated with a Tumor-Specific Antigenic Peptide Encoded by Gene MAGE-3 von Coulie, Pierre G., Karanikas, Vaios, Colau, Didier, Lurquin, Christophe, Landry, Claire, Marchand, Marie, Dorval, Thierry, Brichard, Vincent, Boon, Thierry

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Mannan-MUC1–Pulsed Dendritic Cell Immunotherapy: A Phase I Trial in Patients with Adenocarcinoma von LOVELAND, Bruce E, ZHAO, Anne, KYRIAKOU, Peter, MCKENZIE, Ian F. C, MITCHELL, Paul L. R, WHITE, Shane, HUI GAN, HAMILTON, Kate, XING, Pei-Xiang, PIETERSZ, Geoffrey A, APOSTOLOPOULOS, Vasso, VAUGHAN, Hilary, KARANIKAS, Vaios

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Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy von Gnjatic, Sacha, Bronte, Vincenzo, Brunet, Laura Rosa, Butler, Marcus O, Disis, Mary L, Galon, Jérôme, Hakansson, Leif G, Hanks, Brent A, Karanikas, Vaios, Khleif, Samir N, Kirkwood, John M, Miller, Lance D, Schendel, Dolores J, Tanneau, Isabelle, Wigginton, Jon M, Butterfield, Lisa H

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Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume I—conceptual challenges von Rutella, Sergio, Cannarile, Michael A, Gnjatic, Sacha, Gomes, Bruno, Guinney, Justin, Karanikas, Vaios, Karkada, Mohan, Kirkwood, John M, Kotlan, Beatrix, Masucci, Giuseppe V, Meeusen, Els, Monette, Anne, Naing, Aung, Thorsson, Vésteinn, Tschernia, Nicholas, Wang, Ena, Wells, Daniel K, Wyant, Timothy L, Cesano, Alessandra

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Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume II—practical challenges von Cesano, Alessandra, Cannarile, Michael A, Gnjatic, Sacha, Gomes, Bruno, Guinney, Justin, Karanikas, Vaios, Karkada, Mohan, Kirkwood, John M, Kotlan, Beatrix, Masucci, Giuseppe V, Meeusen, Els, Monette, Anne, Naing, Aung, Thorsson, Vésteinn, Tschernia, Nicholas, Wang, Ena, Wells, Daniel K, Wyant, Timothy L, Rutella, Sergio

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Foxp3 Expression in Liver Correlates with the Degree but Not the Cause of Inflammation von Speletas, Matthaios, Argentou, Nikoletta, Germanidis, Georgios, Vasiliadis, Themistoclis, Mantzoukis, Konstantinos, Patsiaoura, Kalliopi, Nikolaidis, Pavlos, Karanikas, Vaios, Ritis, Konstantinos, Germenis, Anastasios E.

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A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade von Thommen, Daniela S., Koelzer, Viktor H., Herzig, Petra, Roller, Andreas, Trefny, Marcel, Dimeloe, Sarah, Kiialainen, Anna, Hanhart, Jonathan, Schill, Catherine, Hess, Christoph, Savic Prince, Spasenija, Wiese, Mark, Lardinois, Didier, Ho, Ping-Chih, Klein, Christian, Karanikas, Vaios, Mertz, Kirsten D., Schumacher, Ton N., Zippelius, Alfred

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A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors von Bacac, Marina, Fauti, Tanja, Sam, Johannes, Colombetti, Sara, Weinzierl, Tina, Ouaret, Djamila, Bodmer, Walter, Lehmann, Steffi, Hofer, Thomas, Hosse, Ralf J, Moessner, Ekkehard, Ast, Oliver, Bruenker, Peter, Grau-Richards, Sandra, Schaller, Teilo, Seidl, Annette, Gerdes, Christian, Perro, Mario, Nicolini, Valeria, Steinhoff, Nathalie, Dudal, Sherri, Neumann, Sebastian, von Hirschheydt, Thomas, Jaeger, Christiane, Saro, Jose, Karanikas, Vaios, Klein, Christian, Umaña, Pablo

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Biomarker Technologies to Support Early Clinical Immuno-oncology Development: Advances and Interpretation von Cannarile, Michael A, Gomes, Bruno, Canamero, Marta, Reis, Bernhard, Byrd, Allyson, Charo, Jehad, Yadav, Mahesh, Karanikas, Vaios

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Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors von Thommen, Daniela S, Schreiner, Jens, Müller, Philipp, Herzig, Petra, Roller, Andreas, Belousov, Anton, Umana, Pablo, Pisa, Pavel, Klein, Christian, Bacac, Marina, Fischer, Ozana S, Moersig, Wolfgang, Savic Prince, Spasenija, Levitsky, Victor, Karanikas, Vaios, Lardinois, Didier, Zippelius, Alfred

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CD25 Targeting Eliminates Regulatory T Cells and CD25+ Blasts in Acute Myeloid Leukemia von Pousse, Laurene, Medeiros, Bruno C., Korfi, Koorosh, Berrera, Marco, Kumpesa, Nadine, Griesser, Vera, Eckmann, Jan, Karanikas, Vaios, Klein, Christian, Amann, Maria

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Co-expression patterns of tumor-associated antigen genes by non-small cell lung carcinomas: Implications for immunotherapy von Karanikas, Vaios, Tsochas, Stefanos, Boukas, Konstantinos, Kerenidi, Theodora, Nakou, Marianna, Dahabreh, Jubrail, Poularakis, Theodoros, Gourgoulianis, Konstantinos I., Germenis, Anastasios E.

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Flow Cytometric Measurement of Intracellular Cytokines Detects Immune Responses in MUC1 Immunotherapy von Karanikas, V, Lodding, J, Maino, V C, McKenzie, I F

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Three-dimensional colon cancer organoids model the response to CEA-CD3 T-cell engagers von Teijeira, Alvaro, Migueliz, Itziar, Garasa, Saray, Karanikas, Vaios, Luri, Carlos, Cirella, Asunta, Olivera, Irene, Cañamero, Marta, Alvarez, Maite, Ochoa, Maria C, Rouzaut, Ana, Rodriguez-Ruiz, Maria E, Sanmamed, Miguel F, Klein, Christian, Umaña, Pablo, Ponz, Mariano, Bacac, Marina, Melero, Ignacio

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Cytolytic T-cell response against Epstein-Barr virus in lung cancer patients and healthy subjects von Karanikas, Vaios, Zamanakou, Maria, Soukou, Faye, Kerenidi, Theodora, Tsougos, Ioannis, Theodorou, Kiki, Georgoulias, Panagiotis, Gourgoulianis, Konstantinos I, Germenis, Anastasios E

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