Safety and Immunogenicity of an Anti–Zika Virus DNA Vaccine von Tebas, Pablo, Roberts, Christine C, Muthumani, Kar, Reuschel, Emma L, Kudchodkar, Sagar B, Zaidi, Faraz I, White, Scott, Khan, Amir S, Racine, Trina, Choi, Hyeree, Boyer, Jean, Park, Young K, Trottier, Sylvie, Remigio, Celine, Krieger, Diane, Spruill, Susan E, Bagarazzi, Mark, Kobinger, Gary P, Weiner, David B, Maslow, Joel N

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Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial von Modjarrad, Kayvon, Roberts, Christine C, Mills, Kristin T, Castellano, Amy R, Paolino, Kristopher, Muthumani, Kar, Reuschel, Emma L, Robb, Merlin L, Racine, Trina, Oh, Myoung-don, Lamarre, Claude, Zaidi, Faraz I, Boyer, Jean, Kudchodkar, Sagar B, Jeong, Moonsup, Darden, Janice M, Park, Young K, Scott, Paul T, Remigio, Celine, Parikh, Ajay P, Wise, Megan C, Patel, Ami, Duperret, Elizabeth K, Kim, Kevin Y, Choi, Hyeree, White, Scott, Bagarazzi, Mark, May, Jeanine M, Kane, Deborah, Lee, Hyojin, Kobinger, Gary, Michael, Nelson L, Weiner, David B, Thomas, Stephen J, Maslow, Joel N

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Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells von Adeniji, Opeyemi S, Kuri-Cervantes, Leticia, Yu, Chenfei, Xu, Ziyang, Ho, Michelle, Chew, Glen M, Shikuma, Cecilia, Tomescu, Costin, George, Ashley F, Roan, Nadia R, Ndhlovu, Lishomwa C, Liu, Qin, Muthumani, Kar, Weiner, David B, Betts, Michael R, Xiao, Han, Abdel-Mohsen, Mohamed

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Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics von Khoshnejad, Makan, Patel, Ami, Wojtak, Krzysztof, Kudchodkar, Sagar B., Humeau, Laurent, Lyssenko, Nicholas N., Rader, Daniel J., Muthumani, Kar, Weiner, David B.

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Engineered DNA Vaccination against Follicle-Stimulating Hormone Receptor Delays Ovarian Cancer Progression in Animal Models von Perales-Puchalt, Alfredo, Wojtak, Krzysztof, Duperret, Elizabeth K., Yang, Xue, Slager, Anna M., Yan, Jian, Muthumani, Kar, Montaner, Luis J., Weiner, David B.

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In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus von Esquivel, Rianne N., Patel, Ami, Kudchodkar, Sagar B., Park, Daniel H., Stettler, Karin, Beltramello, Martina, Allen, Jeffrey W., Mendoza, Janess, Ramos, Stephanie, Choi, Hyeree, Borole, Piyush, Asija, Kanika, Bah, Mamadou, Shaheen, Shareef, Chen, Jing, Yan, Jian, Durham, Amy C., Smith, Trevor R.F., Broderick, Kate, Guibinga, Ghiabe, Muthumani, Kar, Corti, Davide, Humeau, Laurent, Weiner, David B.

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Development of Siglec-9 Blocking Antibody to Enhance Anti-Tumor Immunity von Choi, Hyeree, Ho, Michelle, Adeniji, Opeyemi S., Giron, Leila, Bordoloi, Devivasha, Kulkarni, Abhijeet J., Puchalt, Alfredo Perales, Abdel-Mohsen, Mohamed, Muthumani, Kar

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DNA vaccination protects mice against Zika virus-induced damage to the testes von Griffin, Bryan D., Muthumani, Kar, Warner, Bryce M., Majer, Anna, Hagan, Mable, Audet, Jonathan, Stein, Derek R., Ranadheera, Charlene, Racine, Trina, De La Vega, Marc-Antoine, Piret, Jocelyne, Kucas, Stephanie, Tran, Kaylie N., Frost, Kathy L., De Graff, Christine, Soule, Geoff, Scharikow, Leanne, Scott, Jennifer, McTavish, Gordon, Smid, Valerie, Park, Young K., Maslow, Joel N., Sardesai, Niranjan Y., Kim, J. Joseph, Yao, Xiao-jian, Bello, Alexander, Lindsay, Robbin, Boivin, Guy, Booth, Stephanie A., Kobasa, Darwyn, Embury-Hyatt, Carissa, Safronetz, David, Weiner, David B., Kobinger, Gary P.

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Integration of needle-free jet injection with advanced electroporation delivery enhances the magnitude, kinetics, and persistence of engineered DNA vaccine induced immune responses von Jiang, Jingjing, Ramos, Stephanie J., Bangalore, Preeti, Fisher, Paul, Germar, Kristine, Lee, Brian K., Williamson, Dan, Kemme, Andrea, Schade, Eric, McCoy, Jay, Muthumani, Kar, Weiner, David B., Humeau, Laurent M., Broderick, Kate E.

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Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy von Flingai, Seleeke, Plummer, Emily M., Patel, Ami, Shresta, Sujan, Mendoza, Janess M., Broderick, Kate E., Sardesai, Niranjan Y., Muthumani, Kar, Weiner, David B.

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Immune response enhancement with GLS-5310 DNA primary vaccine against SARS-CoV-2 followed by administration of an mRNA vaccine heterologous boost von Kim, Woo Joo, Roberts, Christine C., Song, Joon Young, Yoon, Jin Gu, Seong, Hye, Hyun, Hak-Jun, Lee, Hyojin, Gil, Areum, Oh, Yeeun, Park, Ji-Eun, Lee, Ji-Eun, Jeon, Bohyun, Kane, Deborah, Spruill, Susan, Kudchodkar, Sagar B., Muthumani, Kar, Park, Young K., Kwon, Ijoo, Maslow, Joel N.

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An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model von Patel, Ami, DiGiandomenico, Antonio, Keller, Ashley E., Smith, Trevor R. F., Park, Daniel H., Ramos, Stephanie, Schultheis, Katherine, Elliott, Sarah T. C., Mendoza, Janess, Broderick, Kate E., Wise, Megan C., Yan, Jian, Jiang, Jingjing, Flingai, Seleeke, Khan, Amir S., Muthumani, Kar, Humeau, Laurent, Cheng, Lily I., Wachter-Rosati, Leslie, Stover, C. Kendall, Sardesai, Niranjan Y., Weiner, David B.

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Protective immunity by an engineered DNA vaccine for Mayaro virus von Choi, Hyeree, Kudchodkar, Sagar B, Reuschel, Emma L, Asija, Kanika, Borole, Piyush, Ho, Michelle, Wojtak, Krzysztof, Reed, Charles, Ramos, Stephanie, Bopp, Nathen E, Aguilar, Patricia V, Weaver, Scott C, Kim, J Joseph, Humeau, Laurent, Tebas, Pablo, Weiner, David B, Muthumani, Kar

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Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines von Patel, Ami, Reuschel, Emma L, Kraynyak, Kimberly A, Racine, Trina, Park, Daniel H, Scott, Veronica L, Audet, Jonathan, Amante, Dinah, Wise, Megan C, Keaton, Amelia A, Wong, Gary, Villarreal, Daniel O, Walters, Jewell, Muthumani, Kar, Shedlock, Devon J, de La Vega, Marc-Antoine, Plyler, Ross, Boyer, Jean, Broderick, Kate E, Yan, Jian, Khan, Amir S, Jones, Shane, Bello, Alexander, Soule, Geoff, Tran, Kaylie N, He, Shihua, Tierney, Kevin, Qiu, Xiangguo, Kobinger, Gary P, Sardesai, Niranjan Y, Weiner, David B

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Active Immunoprophylaxis and Vaccine Augmentations Mediated by a Novel Plasmid DNA Formulation von Schommer, Nina N, Nguyen, Jacklyn, Yung, Bryan S, Schultheis, Katherine, Muthumani, Kar, Weiner, David B, Humeau, Laurent, Broderick, Kate E, Smith, Trevor R F

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Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2 von Saini, Pratima, Adeniji, Opeyemi S, Bordoloi, Devivasha, Kinslow, Jennifer, Martinson, Jeff, Parent, Danielle M, Hong, Kai Ying, Koshy, Jane, Kulkarni, Abhijeet J, Zilberstein, Netanel F, Balk, Robert A, Moy, James N, Giron, Leila B, Tracy, Russell P, Keshavarzian, Ali, Muthumani, Kar, Landay, Alan, Weiner, David B, Abdel-Mohsen, Mohamed

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Safety and immunogenicity of the bi-cistronic GLS-5310 COVID-19 DNA vaccine delivered with the GeneDerm suction device von Kim, Woo Joo, Roberts, Christine C., Song, Joon Young, Yoon, Jin Gu, Seong, Hye, Hyun, Hak-Jun, Lee, Hyojin, Gil, Areum, Oh, Yeeun, Park, Ji-eun, Jeon, Bohyun, Lee, Ji-Eun, Choi, Sang Kyu, Yoon, Sun Kyung, Lee, Sunhee, Kim, Byoungguk, Kane, Deborah, Spruill, Susan, Kudchodkar, Sagar B., Muthumani, Kar, Park, Young K., Kwon, Ijoo, Jeong, Moonsup, Maslow, Joel N.

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A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus von Choi, Hyeree, Kudchodkar, Sagar B, Ho, Michelle, Reuschel, Emma L, Reynolds, Erin, Xu, Ziyang, Bordoloi, Devivasha, Ugen, Kenneth E, Tebas, Pablo, Kim, Joseph, Abdel-Mohsen, Mohamed, Thangamani, Saravanan, Weiner, David B, Muthumani, Kar

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HIV and HIV‐Tat inhibit LPS‐induced IL‐27 production in human macrophages by distinct intracellular signaling pathways von Gajanayaka, Niranjala, O’Hara, Shifawn, Konarski, Yulia, Fernandes, Jason, Muthumani, Kar, Kozlowski, Maya, Angel, Jonathan B., Kumar, Ashok

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In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model von Patel, Ami, Park, Daniel H., Davis, Carl W., Smith, Trevor R.F., Leung, Anders, Tierney, Kevin, Bryan, Aubrey, Davidson, Edgar, Yu, Xiaoying, Racine, Trina, Reed, Charles, Gorman, Marguerite E., Wise, Megan C., Elliott, Sarah T.C., Esquivel, Rianne, Yan, Jian, Chen, Jing, Muthumani, Kar, Doranz, Benjamin J., Saphire, Erica Ollmann, Crowe, James E., Broderick, Kate E., Kobinger, Gary P., He, Shihua, Qiu, Xiangguo, Kobasa, Darwyn, Humeau, Laurent, Sardesai, Niranjan Y., Ahmed, Rafi, Weiner, David B.

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