The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Mode... von Zmurko, Joanna, Marques, Rafael E, Schols, Dominique, Verbeken, Erik, Kaptein, Suzanne J F, Neyts, Johan

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A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction von Kaptein, Suzanne J. F., Goethals, Olivia, Kiemel, Dominik, Marchand, Arnaud, Kesteleyn, Bart, Bonfanti, Jean-François, Bardiot, Dorothée, Stoops, Bart, Jonckers, Tim H. M., Dallmeier, Kai, Geluykens, Peggy, Thys, Kim, Crabbe, Marjolein, Chatel-Chaix, Laurent, Münster, Max, Querat, Gilles, Touret, Franck, de Lamballerie, Xavier, Raboisson, Pierre, Simmen, Kenny, Chaltin, Patrick, Bartenschlager, Ralf, Van Loock, Marnix, Neyts, Johan

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A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate von Sanchez-Felipe, Lorena, Vercruysse, Thomas, Sharma, Sapna, Ma, Ji, Lemmens, Viktor, Van Looveren, Dominique, Arkalagud Javarappa, Mahadesh Prasad, Boudewijns, Robbert, Malengier-Devlies, Bert, Liesenborghs, Laurens, Kaptein, Suzanne J. F., De Keyzer, Carolien, Bervoets, Lindsey, Debaveye, Sarah, Rasulova, Madina, Seldeslachts, Laura, Li, Li-Hsin, Jansen, Sander, Yakass, Michael Bright, Verstrepen, Babs E., Böszörményi, Kinga P., Kiemenyi-Kayere, Gwendoline, van Driel, Nikki, Quaye, Osbourne, Zhang, Xin, ter Horst, Sebastiaan, Mishra, Niraj, Deboutte, Ward, Matthijnssens, Jelle, Coelmont, Lotte, Vandermeulen, Corinne, Heylen, Elisabeth, Vergote, Valentijn, Schols, Dominique, Wang, Zhongde, Bogers, Willy, Kuiken, Thijs, Verschoor, Ernst, Cawthorne, Christopher, Van Laere, Koen, Opdenakker, Ghislain, Vande Velde, Greetje, Weynand, Birgit, Teuwen, Dirk E., Matthys, Patrick, Neyts, Johan, Jan Thibaut, Hendrik, Dallmeier, Kai

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Reverse engineering synthetic antiviral amyloids von Michiels, Emiel, Roose, Kenny, Gallardo, Rodrigo, Khodaparast, Ladan, Khodaparast, Laleh, van der Kant, Rob, Siemons, Maxime, Houben, Bert, Ramakers, Meine, Wilkinson, Hannah, Guerreiro, Patricia, Louros, Nikolaos, Kaptein, Suzanne J. F., Ibañez, Lorena Itatí, Smet, Anouk, Baatsen, Pieter, Liu, Shu, Vorberg, Ina, Bormans, Guy, Neyts, Johan, Saelens, Xavier, Rousseau, Frederic, Schymkowitz, Joost

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Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals von Tricot, Tine, Helsen, Nicky, Kaptein, Suzanne J F, Neyts, Johan, Verfaillie, Catherine M

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STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters von Boudewijns, Robbert, Thibaut, Hendrik Jan, Kaptein, Suzanne J. F., Li, Rong, Vergote, Valentijn, Seldeslachts, Laura, Van Weyenbergh, Johan, De Keyzer, Carolien, Bervoets, Lindsey, Sharma, Sapna, Liesenborghs, Laurens, Ma, Ji, Jansen, Sander, Van Looveren, Dominique, Vercruysse, Thomas, Wang, Xinyu, Jochmans, Dirk, Martens, Erik, Roose, Kenny, De Vlieger, Dorien, Schepens, Bert, Van Buyten, Tina, Jacobs, Sofie, Liu, Yanan, Martí-Carreras, Joan, Vanmechelen, Bert, Wawina-Bokalanga, Tony, Delang, Leen, Rocha-Pereira, Joana, Coelmont, Lotte, Chiu, Winston, Leyssen, Pieter, Heylen, Elisabeth, Schols, Dominique, Wang, Lanjiao, Close, Lila, Matthijnssens, Jelle, Van Ranst, Marc, Compernolle, Veerle, Schramm, Georg, Van Laere, Koen, Saelens, Xavier, Callewaert, Nico, Opdenakker, Ghislain, Maes, Piet, Weynand, Birgit, Cawthorne, Christopher, Vande Velde, Greetje, Wang, Zhongde, Neyts, Johan, Dallmeier, Kai

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Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters von Abdelnabi, Rana, Boudewijns, Robbert, Foo, Caroline S., Seldeslachts, Laura, Sanchez-Felipe, Lorena, Zhang, Xin, Delang, Leen, Maes, Piet, Kaptein, Suzanne J.F., Weynand, Birgit, Vande Velde, Greetje, Neyts, Johan, Dallmeier, Kai

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The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model von Abdelnabi, Rana, Foo, Caroline S., Kaptein, Suzanne J.F., Zhang, Xin, Do, Thuc Nguyen Dan, Langendries, Lana, Vangeel, Laura, Breuer, Judith, Pang, Juanita, Williams, Rachel, Vergote, Valentijn, Heylen, Elisabeth, Leyssen, Pieter, Dallmeier, Kai, Coelmont, Lotte, Chatterjee, Arnab K., Mols, Raf, Augustijns, Patrick, De Jonghe, Steven, Jochmans, Dirk, Weynand, Birgit, Neyts, Johan

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Multiplexed multicolor antiviral assay amenable for high-throughput research von Li, Li-Hsin, Chiu, Winston, Huang, Yun-An, Rasulova, Madina, Vercruysse, Thomas, Thibaut, Hendrik Jan, ter Horst, Sebastiaan, Rocha-Pereira, Joana, Vanhoof, Greet, Borrenberghs, Doortje, Goethals, Olivia, Kaptein, Suzanne J. F., Leyssen, Pieter, Neyts, Johan, Dallmeier, Kai

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Broad antiviral activity of carbohydrate-binding agents against the four serotypes of dengue virus in monocyte-derived dendritic cells von Alen, Marijke M F, De Burghgraeve, Tine, Kaptein, Suzanne J F, Balzarini, Jan, Neyts, Johan, Schols, Dominique

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Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro von Radoshitzky, Sheli R., Iversen, Patrick, Lu, Xianghan, Zou, Jing, Kaptein, Suzanne J. F., Stuthman, Kelly S., Van Tongeren, Sean A., Steffens, Jesse, Gong, Ruoyu, Truong, Hoa, Sapre, Annapurna A., Yang, Huiling, Xie, Xiaodong, Chia, Jia Jun, Song, Zhijuan J., Leventhal, Stacey M., Chan, Josolyn, Shornikov, Alex, Zhang, Xin, Cowfer, David, Yu, Helen, Warren, Travis, Cihlar, Tomas, Porter, Danielle P., Neyts, Johan, Shi, Pei-Yong, Wells, Jay, Bilello, John P., Feng, Joy Y.

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Establishment of a robust rat hepatitis E virus fecal-oral infection model and validation for antiviral studies von Zhang, Xin, Cremers, Niels, Hendrickx, Stijn, Debing, Yannick, Roskams, Tania, Coelmont, Lotte, Neyts, Johan, Kaptein, Suzanne J.F.

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A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice von Jacobs, Sofie, Delang, Leen, Verbeken, Eric, Neyts, Johan, Kaptein, Suzanne J F

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Animal models for COVID-19 von Muñoz-Fontela, César, Dowling, William E., Funnell, Simon G. P., Gsell, Pierre-S., Riveros-Balta, A. Ximena, Albrecht, Randy A., Andersen, Hanne, Baric, Ralph S., Carroll, Miles W., Cavaleri, Marco, Qin, Chuan, Crozier, Ian, Dallmeier, Kai, de Waal, Leon, de Wit, Emmie, Delang, Leen, Dohm, Erik, Duprex, W. Paul, Falzarano, Darryl, Finch, Courtney L., Frieman, Matthew B., Graham, Barney S., Gralinski, Lisa E., Guilfoyle, Kate, Haagmans, Bart L., Hamilton, Geraldine A., Hartman, Amy L., Herfst, Sander, Kaptein, Suzanne J. F., Klimstra, William B., Knezevic, Ivana, Krause, Philip R., Kuhn, Jens H., Le Grand, Roger, Lewis, Mark G., Liu, Wen-Chun, Maisonnasse, Pauline, McElroy, Anita K., Munster, Vincent, Oreshkova, Nadia, Rasmussen, Angela L., Rocha-Pereira, Joana, Rockx, Barry, Rodríguez, Estefanía, Rogers, Thomas F., Salguero, Francisco J., Schotsaert, Michael, Stittelaar, Koert J., Thibaut, Hendrik Jan, Tseng, Chien-Te, Vergara-Alert, Júlia, Beer, Martin, Brasel, Trevor, Chan, Jasper F. W., García-Sastre, Adolfo, Neyts, Johan, Perlman, Stanley, Reed, Douglas S., Richt, Juergen A., Roy, Chad J., Segalés, Joaquim, Vasan, Seshadri S., Henao-Restrepo, Ana María, Barouch, Dan H.

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Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains von Aubry, Fabien, Jacobs, Sofie, Darmuzey, Maïlis, Lequime, Sebastian, Delang, Leen, Fontaine, Albin, Jupatanakul, Natapong, Miot, Elliott F., Dabo, Stéphanie, Manet, Caroline, Montagutelli, Xavier, Baidaliuk, Artem, Gámbaro, Fabiana, Simon-Lorière, Etienne, Gilsoul, Maxime, Romero-Vivas, Claudia M., Cao-Lormeau, Van-Mai, Jarman, Richard G., Diagne, Cheikh T., Faye, Oumar, Faye, Ousmane, Sall, Amadou A., Neyts, Johan, Nguyen, Laurent, Kaptein, Suzanne J. F., Lambrechts, Louis

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A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection von Abdelnabi, Rana, Foo, Caroline S., Kaptein, Suzanne J. F., Boudewijns, Robbert, Vangeel, Laura, De Jonghe, Steven, Jochmans, Dirk, Weynand, Birgit, Neyts, Johan

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A Derivate of the Antibiotic Doxorubicin Is a Selective Inhibitor of Dengue and Yellow Fever Virus Replication In Vitro von KAPTEIN, Suzanne J. F, DE BURGHGRAEVE, Tine, GAMARNIK, Andrea V, SZTARICSKAI, Ferenc, NEYTS, Johan, FROEYEN, Mathy, PASTORINO, Boris, ALEN, Marijke M. F, MONDOTTE, Juan A, HERDEWIJN, Piet, JACOBS, Michael, DE LAMBALLERIE, Xavier, SCHOLS, Dominique

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Favipiravir inhibits in vitro Usutu virus replication and delays disease progression in an infection model in mice von Segura Guerrero, Nidya A., Sharma, Sapna, Neyts, Johan, Kaptein, Suzanne J.F.

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Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation von Kiemel, Dominik, Kroell, Ann-Sophie Helene, Denolly, Solène, Haselmann, Uta, Bonfanti, Jean-François, Andres, Jose Ignacio, Ghosh, Brahma, Geluykens, Peggy, Kaptein, Suzanne J. F., Wilken, Lucas, Scaturro, Pietro, Neyts, Johan, Van Loock, Marnix, Goethals, Olivia, Bartenschlager, Ralf

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Scaffold Morphing Approach To Expand the Toolbox of Broad-Spectrum Antivirals Blocking Dengue/Zika Replication von Vincetti, Paolo, Kaptein, Suzanne J. F, Costantino, Gabriele, Neyts, Johan, Radi, Marco

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