IDH mutation impairs histone demethylation and results in a block to cell differentiation von Lu, Chao, Ward, Patrick S., Kapoor, Gurpreet S., Rohle, Dan, Turcan, Sevin, Abdel-Wahab, Omar, Edwards, Christopher R., Khanin, Raya, Figueroa, Maria E., Melnick, Ari, Wellen, Kathryn E., O’Rourke, Donald M., Berger, Shelley L., Chan, Timothy A., Levine, Ross L., Mellinghoff, Ingo K., Thompson, Craig B.

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Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma von Walsh, Alice M, Kapoor, Gurpreet S, Buonato, Janine M, Mathew, Lijoy K, Bi, Yingtao, Davuluri, Ramana V, Martinez-Lage, Maria, Simon, M Celeste, O'Rourke, Donald M, Lazzara, Matthew J

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Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells von Ayuso-Sacido, Angel, Moliterno, Jennifer A., Kratovac, Sebila, Kapoor, Gurpreet S., O’Rourke, Donald M., Holland, Eric C., García-Verdugo, Jose Manuel, Roy, Neeta S., Boockvar, John A.

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Prediction of oligodendroglial tumor subtype and grade using perfusion weighted magnetic resonance imaging von WHITMORE, Robert G, KREJZA, Jaroslaw, BIEGEL, Jaclyn A, MELHEM, Elias R, O'ROURKE, Donald M, KAPOOR, Gurpreet S, HUSE, Jason, WOO, John H, BLOOM, Stephanie, LOPINTO, Joanna, WOLF, Ronald L, JUDY, Kevin, ROSENFELD, Myrna R

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EGFR inhibition in glioblastoma cells induces G2/M arrest and is independent of p53 von Kapoor, Gurpreet S., Christie, Antoire, O'Rourke, Donald M.

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Receptor Tyrosine Kinase Signaling In Gliomagenesis: Pathobiology And Therapeutic Approaches von Kapoor, Gurpreet S., O'Rourke, Donald M.

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Use of magnetic perfusion-weighted imaging to determine epidermal growth factor receptor variant III expression in glioblastoma von Tykocinski, Elana S, Grant, Ryan A, Kapoor, Gurpreet S, Krejza, Jaroslaw, Bohman, Leif-Erik, Gocke, Timothy A, Chawla, Sanjeev, Halpern, Casey H, Lopinto, Joanna, Melhem, Elias R, O'Rourke, Donald M

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Safety and efficacy of letetresgene autoleucel alone or with pembrolizumab for relapsed/refractory multiple myeloma von Nishihori, Taiga, Hoffman, James E., Huff, Anne, Kapoor, Gurpreet S., Eleftheriadou, Ioanna, Zajic, Stefan, Urbano, Alisa, Suchindran, Sunil, Chisamore, Michael, D’Souza, Jimson W., Faitg, Thomas, Rapoport, Aaron P.

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Critical Role of Diacylglycerol- and Phospholipid-Regulated Protein Kinase Cε in Induction of Low-Density Lipoprotein Receptor Transcription in Response to Depletion of Cholesterol... von Mehta, Kamal D., Radominska-Pandya, Anna, Kapoor, Gurpreet S., Dave, Bhuvanesh, Atkins, Brett A.

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Magnetic resonance perfusion-weighted imaging defines angiogenic subtypes of oligodendroglioma according to 1p19q and EGFR status von Kapoor, Gurpreet S., Gocke, Timothy A., Chawla, Sanjeev, Whitmore, Robert G., Nabavizadeh, Ali, Krejza, Jaroslaw, Lopinto, Joanna, Plaum, Justin, Maloney-Wilensky, Eileen, Poptani, Harish, Melhem, Elias R., Judy, Kevin D., O’Rourke, Donald M.

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pp90RSK- and protein kinase C-dependent pathway regulates p42/44MAPK-induced LDL receptor transcription in HepG2 cells von Kapoor, Gurpreet S, Golden, Carmen, Atkins, Brett, Mehta, Kamal D

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Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models von Benetatos, Christopher A, Mitsuuchi, Yasuhiro, Burns, Jennifer M, Neiman, Eric M, Condon, Stephen M, Yu, Guangyao, Seipel, Martin E, Kapoor, Gurpreet S, Laporte, Matthew G, Rippin, Susan R, Deng, Yijun, Hendi, Mukta S, Tirunahari, Pavan K, Lee, Yu-Hua, Haimowitz, Thomas, Alexander, Matthew D, Graham, Martin A, Weng, David, Shi, Yigong, McKinlay, Mark A, Chunduru, Srinivas K

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Distinct Domains in the SHP-2 Phosphatase Differentially Regulate Epidermal Growth Factor Receptor/NF-κB Activation through Gab1 in Glioblastoma Cells von Kapoor, Gurpreet S., Zhan, Yi, Johnson, Gibbes R., O'Rourke, Donald M.

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Mitogenic signaling cascades in glial tumors von Kapoor, Gurpreet S, O'Rourke, Donald M

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Activation of Raf-1/MEK-1/2/p42/44(MAPK) cascade alone is sufficient to uncouple LDL receptor expression from cell growth von Kapoor, Gurpreet S, Atkins, Brett A, Mehta, Kamal D

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Abstract 1806: Birinapant, a bivalent SMAC-mimetic, promotes efficient cellular IAP E3 ligase activity and formation of a pro-apoptotic RIPK1:caspase-8 complex while monovalent IAP... von Mitsuuchi, Yasuhiro, Benetatos, Christopher A., Haimowitz, Thomas, Deng, Yijun, Mufalli, Angeline C., Seipel, Martin E., Burns, Jennifer M., Kapoor, Gurpreet S., Begley, C. Glenn, Condon, Stephen M.

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One-way Cross-talk between p38MAPK and p42/44MAPK von Singh, Rajesh P., Dhawan, Punita, Golden, Carmen, Kapoor, Gurpreet S., Mehta, Kamal D.

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Abstract 599: Potential biomarkers of Smac mimetic tumor sensitivity: inhibitor of apoptosis protein DNA copy number von Kapoor, Gurpreet S., Geier, Brian, Neiman, Eric M., Mitsuuchi, Yasuhiro, Benetatos, Christopher A., Condon, Stephen M., Chunduru, Srinivas, Begley, C. Glenn

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Abstract 5302: Characterization of tumor cell lines resistant to birinapant, a novel bivalent smac mimetic von Neiman, Eric M., Benetatos, Christopher A., Kapoor, Gurpreet S., Mitsuuchi, Yasuhiro, McKinlay, Mark A., Seipel, Martin E., Yu, Guangyao, Condon, Stephen M., Chunduru, Srinivas K.

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One-way cross-talk between p38(MAPK) and p42/44(MAPK). Inhibition of p38(MAPK) induces low density lipoprotein receptor expression through activation of the p42/44(MAPK) cascade von Singh, R P, Dhawan, P, Golden, C, Kapoor, G S, Mehta, K D

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