Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy von Du, Ruijuan, Huang, Chuntian, Liu, Kangdong, Li, Xiang, Dong, Zigang

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Targeting CDK12 for Cancer Therapy: Function, Mechanism, and Drug Discovery von Liu, Hui, Liu, Kangdong, Dong, Zigang

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Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery von Hu, Yamei, Dong, Zigang, Liu, Kangdong

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EPRS/GluRS promotes gastric cancer development via WNT/GSK-3β/β-catenin signaling pathway von Liu, Hui, Fredimoses, Mangaladoss, Niu, Peijia, Liu, Tingting, Qiao, Yan, Tian, Xueli, Chen, Xiaobing, Kim, Dong Joon, Li, Xiang, Liu, Kangdong, Dong, Zigang

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SDCBP/MDA-9/syntenin phosphorylation by AURKA promotes esophageal squamous cell carcinoma progression through the EGFR-PI3K-Akt signaling pathway von Du, Ruijuan, Huang, Chuntian, Chen, Hanyong, Liu, Kangdong, Xiang, Pu, Yao, Ning, Yang, Lu, Zhou, Liting, Wu, Qiong, Zheng, Yaqiu, Xin, Mingxia, Dong, Zigang, Li, Xiang

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Targeting CRAF kinase in anti-cancer therapy: progress and opportunities von Wang, Penglei, Laster, Kyle, Jia, Xuechao, Dong, Zigang, Liu, Kangdong

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Uncovering the microbiota in renal cell carcinoma tissue using 16S rRNA gene sequencing von Wang, Junpeng, Li, Xin, Wu, Xiaoqiang, Wang, Zhiwei, Zhang, Chan, Cao, Guanghui, Liu, Kangdong, Yan, Tianzhong

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The Role of p21-Activated Kinases in Cancer and Beyond: Where Are We Heading? von Liu, Hui, Liu, Kangdong, Dong, Zigang

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Knockdown of Pyruvate Kinase M Inhibits Cell Growth and Migration by Reducing NF-kB Activity in Triple-Negative Breast Cancer Cells von Ma, Chaobing, Zu, Xueyin, Liu, Kangdong, Bode, Ann M, Dong, Zigang, Liu, Zhenzhen, Kim, Dong Joon

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CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway von Huang, Chuntian, Du, Ruijuan, Jia, Xuechao, Liu, Kangdong, Qiao, Yan, Wu, Qiong, Yao, Ning, Yang, Lu, Zhou, Liting, Liu, Xuejiao, Xiang, Pu, Xin, Mingxia, Wang, Yan, Chen, Xiaojie, Kim, Dong Joon, Dong, Zigang, Li, Xiang

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Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo von Song, Mengqiu, Liu, Xuejiao, Liu, Kangdong, Zhao, Ran, Huang, Hai, Shi, Yuanyuan, Zhang, Man, Zhou, Silei, Xie, Hua, Chen, Hanyong, Li, Yin, Zheng, Yan, Wu, Qiong, Liu, Fangfang, Li, Enmin, Bode, Ann M, Dong, Zigang, Lee, Mee-Hyun

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Spatial transcriptomics analysis of esophageal squamous precancerous lesions and their progression to esophageal cancer von Liu, Xuejiao, Zhao, Simin, Wang, Keke, Zhou, Liting, Jiang, Ming, Gao, Yunfeng, Yang, Ran, Yan, Shiwen, Zhang, Wen, Lu, Bingbing, Liu, Feifei, Zhao, Ran, Liu, Wenting, Zhang, Zihan, Liu, Kangdong, Li, Xiang, Dong, Zigang

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Ubiquitination of ADRα1d/SerpinA1 complex stimulates hypoxia to induce gastric tumorigenesis with a combination of Helicobacter pylori and chronic stress through IL-1α von Aziz, Faisal, Li, Xiang, Chakraborty, Abhijit, Zheng, Yaqiu, Xin, Mingxia, Liu, Kangdong, Dong, Zigang

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BRD4 drives esophageal squamous cell carcinoma growth by promoting RCC2 expression von Wu, Qiong, Liu, Fangfang, Ge, Mengmeng, Laster, Kyle Vaughn, Wei, Lixiao, Du, Ruijuan, Jiang, Ming, Zhang, Jing, Zhi, Yafei, Jin, Guoguo, Zhao, Simin, Kim, Dong Joon, Dong, Zigang, Liu, Kangdong

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Mutations found in cancer patients compromise DNA binding of the winged helix protein STK19 von Li, Jian, Ma, Xinli, Wang, Xiaoyu, Hu, Xiaotong, Fang, Shaobo, Jin, Guoguo, Liu, Kangdong, Dong, Zigang

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Cancer/testis antigens: promising immunotherapy targets for digestive tract cancers von Ai, Huihan, Yang, Hang, Li, Liang, Ma, Jie, Liu, Kangdong, Li, Zhi

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Integrated metabolomic and transcriptomic analyses of Dendrobium chrysotoxum and D. thyrsiflorum reveal the biosynthetic pathway from gigantol to erianin von Xie, Lihang, Chen, Qiuying, Cheng, Najing, Zhang, Yue, Ma, Yao, Zhang, Yueteng, Liu, Kangdong

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Targeted therapy of the AKT kinase inhibits esophageal squamous cell carcinoma growth in vitro and in vivo von Liu, Xuejiao, Song, Mengqiu, Wang, Penglei, Zhao, Ran, Chen, Hanyong, Zhang, Man, Shi, Yuanyuan, Liu, Kangdong, Liu, Fangfang, Yang, Ran, Li, Enmin, Bode, Ann M., Dong, Zigang, Lee, Mee‐Hyun

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Periplogenin suppresses the growth of esophageal squamous cell carcinoma in vitro and in vivo by targeting STAT3 von Hu, Yamei, Liu, Fangfang, Jia, Xuechao, Wang, Penglei, Gu, Tingxuan, Liu, Hui, Liu, Tingting, Wei, Huifang, Chen, Hanyong, Zhao, Jiuzhou, Yang, Ran, Chen, Yingying, Dong, Zigang, Liu, Kangdong

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Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer von Tian, Xueli, Wang, Rui, Gu, Tingxuan, Ma, Fayang, Laster, Kyle Vaughn, Li, Xiang, Liu, Kangdong, Lee, Mee-Hyun, Dong, Zigang

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