Hit and lead criteria in drug discovery for infectious diseases of the developing world von Katsuno, Kei, Burrows, Jeremy N., Duncan, Ken, van Huijsduijnen, Rob Hooft, Kaneko, Takushi, Kita, Kiyoshi, Mowbray, Charles E., Schmatz, Dennis, Warner, Peter, Slingsby, B. T.

Volltext

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis von Wang, Feng, Sambandan, Dhinakaran, Halder, Rajkumar, Wang, Jianing, Batt, Sarah M, Weinrick, Brian, Ahmad, Insha, Yang, Pengyu, Zhang, Yong, Kim, John, Hassani, Morad, Huszar, Stanislav, Trefzer, Claudia, Ma, Zhenkun, Kaneko, Takushi, Mdluli, Khisi E, Franzblau, Scott, Chatterjee, Arnab K, Johnsson, Kai, Johnson, Kai, Mikusova, Katarina, Besra, Gurdyal S, Fütterer, Klaus, Robbins, Scott H, Barnes, S Whitney, Walker, John R, Jacobs, Jr, William R, Schultz, Peter G

Volltext

Design, Synthesis, and Structure–Activity Relationship Studies of Tryptanthrins As Antitubercular Agents von Hwang, Jae-Min, Oh, Taegwon, Kaneko, Takushi, Upton, Anna M, Franzblau, Scott G, Ma, Zhenkun, Cho, Sang-Nae, Kim, Pilho

Volltext

New target for inhibition of bacterial RNA polymerase: ‘switch region’ von Srivastava, Aashish, Talaue, Meliza, Liu, Shuang, Degen, David, Ebright, Richard Y, Sineva, Elena, Chakraborty, Anirban, Druzhinin, Sergey Y, Chatterjee, Sujoy, Mukhopadhyay, Jayanta, Ebright, Yon W, Zozula, Alex, Shen, Juan, Sengupta, Sonali, Niedfeldt, Rui Rong, Xin, Cai, Kaneko, Takushi, Irschik, Herbert, Jansen, Rolf, Donadio, Stefano, Connell, Nancy, Ebright, Richard H

Volltext

A novel antimycobacterial compound acts as an intracellular iron chelator von Dragset, Marte S, Poce, Giovanna, Alfonso, Salvatore, Padilla-Benavides, Teresita, Ioerger, Thomas R, Kaneko, Takushi, Sacchettini, James C, Biava, Mariangela, Parish, Tanya, Argüello, José M, Steigedal, Magnus, Rubin, Eric J

Volltext

Aqueous Phosphoric Acid as a Mild Reagent for Deprotection of tert-Butyl Carbamates, Esters, and Ethers von Li, Bryan, Berliner, Martin, Buzon, Richard, Chiu, Charles K.-F, Colgan, Stephen T, Kaneko, Takushi, Keene, Nandell, Kissel, William, Le, Tung, Leeman, Kyle R, Marquez, Brian, Morris, Ronald, Newell, Lisa, Wunderwald, Silke, Witt, Michael, Weaver, John, Zhang, Zhijun, Zhang, Zhongli

Volltext

Tuberculosis drug discovery and emerging targets von Mdluli, Khisimuzi, Kaneko, Takushi, Upton, Anna

Volltext

Antituberculosis Activity of Brotowali (Tinospora crispa) Extract and Fractions against Mycobacterium tuberculosis using Microplate Alamar Blue Assay Method von Wahyuningrum, Retno, Ritmaleni, Ritmaleni, Irianti, Tatang, Wahyuono, Subagus, Kaneko, Takushi, Nuryastuti, Titik

Volltext

The tuberculosis drug discovery and development pipeline and emerging drug targets von Mdluli, Khisimuzi, Kaneko, Takushi, Upton, Anna

Volltext

Effect of InGaN/GaN Superlattice on Lattice Curvature of GaN Layers Grown on Sapphire Substrates von Kaneko, Takushi, Okada, Narihito, Tadatomo, Kazuyuki

Volltext

Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline von Wang, Zhe, Soni, Vijay, Marriner, Gwendolyn, Kaneko, Takushi, Boshoff, Helena I. M., Barry, Clifton E., Rhee, Kyu Y.

Volltext

Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents von Zhang, Jidong, Lair, Christine, Roubert, Christine, Amaning, Kwame, Barrio, María Belén, Benedetti, Yannick, Cui, Zhicheng, Xing, Zhongliang, Li, Xiaojun, Franzblau, Scott G., Baurin, Nicolas, Bordon-Pallier, Florence, Cantalloube, Cathy, Sans, Stephanie, Silve, Sandra, Blanc, Isabelle, Fraisse, Laurent, Rak, Alexey, Jenner, Lasse B., Yusupova, Gulnara, Yusupov, Marat, Zhang, Junjie, Kaneko, Takushi, Yang, T.J., Fotouhi, Nader, Nuermberger, Eric, Tyagi, Sandeep, Betoudji, Fabrice, Upton, Anna, Sacchettini, James C., Lagrange, Sophie

Volltext

Synthesis and structure–activity studies of novel benzocycloheptanone oxazolidinone antibacterial agents von Vara Prasad, J.V.N., Boyer, Frederick E., Chupak, Lou, Dermyer, Michael, Ding, Qizhu, Gavardinas, K., Hagen, Susan E., Huband, Michael D., Jiao, Wenhua, Kaneko, Takushi, Maiti, Samarendra N., Melnick, Michael, Romero, Karina, Patterson, M., Wu, Xiujuan

Volltext

Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents von Zhang, Jidong, Lair, Christine, Roubert, Christine, Amaning, Kwame, Barrio, María Belén, Benedetti, Yannick, Cui, Zhicheng, Xing, Zhongliang, Li, Xiaojun, Franzblau, Scott, Baurin, Nicolas, Bordon-Pallier, Florence, Cantalloube, Cathy, Sans, Stephanie, Silve, Sandra, Blanc, Isabelle, Fraisse, Laurent, Rak, Alexey, Jenner, Lasse, Yusupova, Gulnara, Yusupov, Marat, Zhang, Junjie, Kaneko, Takushi, Yang, T.J., Fotouhi, Nader, Nuermberger, Eric, Tyagi, Sandeep, Betoudji, Fabrice, Upton, Anna, Sacchettini, James, Lagrange, Sophie

Volltext

An antibacterial compound purified from a tropical coastal plant, Diospyros maritima von ISNANSETYO, ALIM, HANDAYANI, DESY PUTRI, ISTIQOMAH, INDAH, ARIF, ADITYA, KANEKO, TAKUSHI

Volltext

Human Kinase IGF1R/IR Inhibitor Linsitinib Controls the In Vitro and Intracellular Growth of Mycobacterium tuberculosis von Wang, Heng, Bi, Jing, Zhang, Yuan, Pan, Miaomiao, Guo, Qinglong, Xiao, Genhui, Cui, Yumeng, Hu, Song, Chan, Chi Kin, Yuan, Ying, Kaneko, Takushi, Zhang, Guoliang, Chen, Shawn

Volltext

Identification and optimization of a new series of anti-tubercular quinazolinones von Couturier, Cédric, Lair, Christine, Pellet, Alain, Upton, Anna, Kaneko, Takushi, Perron, Corinne, Cogo, Eric, Menegotto, Jérome, Bauer, Armin, Scheiper, Bodo, Lagrange, Sophie, Bacqué, Eric

Volltext

(6-Maleimidocaproyl)hydrazone of doxorubicin. A new derivative for the preparation of immunoconjugates of doxorubicin von Willner, David, Trail, Pamela A, Hofstead, Sandra J, King, H. Dalton, Lasch, Shirley J, Braslawsky, Gary R, Greenfield, Robert S, Kaneko, Takushi, Firestone, Raymond A

Volltext

Antibacterial Activity of Coastal Plants and Marine Sponges from Kei Island Indonesia against Bacterial Fish Pathogens von Hamdillah, Andi, Isnansetyo, Alim, Istiqomah, Indah, Puspita, Indun Dewi, Handayani, Desy Putri, Kaneko, Takushi

Volltext

Urinary Protein Excretion after Low-Intensity Walking in Healthy Japanese Elderly Women von Tsuchiya, Y, Shimizu, T, Nosaka, T, Kaneko, T, Shibuya, N, Nakamura, K, Yamamoto, M

Volltext