Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers von Govindan, Ramaswamy, Ding, Li, Griffith, Malachi, Subramanian, Janakiraman, Dees, Nathan D., Kanchi, Krishna L., Maher, Christopher A., Fulton, Robert, Fulton, Lucinda, Wallis, John, Chen, Ken, Walker, Jason, McDonald, Sandra, Bose, Ron, Ornitz, David, Xiong, Donghai, You, Ming, Dooling, David J., Watson, Mark, Mardis, Elaine R., Wilson, Richard K.

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Rapid idiosyncratic mechanisms of clinical resistance to KRAS G12C inhibition von Tsai, Yihsuan S, Woodcock, Mark G, Azam, Salma H, Thorne, Leigh B, Kanchi, Krishna L, Parker, Joel S, Vincent, Benjamin G, Pecot, Chad V

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Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases von Hoadley, Katherine A, Siegel, Marni B, Kanchi, Krishna L, Miller, Christopher A, Ding, Li, Zhao, Wei, He, Xiaping, Parker, Joel S, Wendl, Michael C, Fulton, Robert S, Demeter, Ryan T, Wilson, Richard K, Carey, Lisa A, Perou, Charles M, Mardis, Elaine R

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Evaluation of the economic and environmental impact of combining dry reforming with steam reforming of methane von Gangadharan, Preeti, Kanchi, Krishna C., Lou, Helen H.

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Exome sequencing of Finnish isolates enhances rare-variant association power von Locke, Adam E., Steinberg, Karyn Meltz, Chiang, Charleston W. K., Service, Susan K., Havulinna, Aki S., Stell, Laurel, Pirinen, Matti, Abel, Haley J., Chiang, Colby C., Fulton, Robert S., Jackson, Anne U., Kang, Chul Joo, Kanchi, Krishna L., Koboldt, Daniel C., Larson, David E., Nelson, Joanne, Nicholas, Thomas J., Pietilä, Arto, Ramensky, Vasily, Ray, Debashree, Scott, Laura J., Stringham, Heather M., Vangipurapu, Jagadish, Welch, Ryan, Yajnik, Pranav, Yin, Xianyong, Eriksson, Johan G., Ala-Korpela, Mika, Järvelin, Marjo-Riitta, Männikkö, Minna, Laivuori, Hannele, Dutcher, Susan K., Stitziel, Nathan O., Wilson, Richard K., Hall, Ira M., Sabatti, Chiara, Palotie, Aarno, Salomaa, Veikko, Laakso, Markku, Ripatti, Samuli, Boehnke, Michael, Freimer, Nelson B.

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Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia von Churpek, Jane E., Pyrtel, Khateriaa, Kanchi, Krishna-Latha, Shao, Jin, Koboldt, Daniel, Miller, Christopher A., Shen, Dong, Fulton, Robert, O’Laughlin, Michelle, Fronick, Catrina, Pusic, Iskra, Uy, Geoffrey L., Braunstein, Evan M., Levis, Mark, Ross, Julie, Elliott, Kevin, Heath, Sharon, Jiang, Allan, Westervelt, Peter, DiPersio, John F., Link, Daniel C., Walter, Matthew J., Welch, John, Wilson, Richard, Ley, Timothy J., Godley, Lucy A., Graubert, Timothy A.

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Clonal architectures and driver mutations in metastatic melanomas von Ding, Li, Kim, Minjung, Kanchi, Krishna L, Dees, Nathan D, Lu, Charles, Griffith, Malachi, Fenstermacher, David, Sung, Hyeran, Miller, Christopher A, Goetz, Brian, Wendl, Michael C, Griffith, Obi, Cornelius, Lynn A, Linette, Gerald P, McMichael, Joshua F, Sondak, Vernon K, Fields, Ryan C, Ley, Timothy J, Mulé, James J, Wilson, Richard K, Weber, Jeffrey S

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Patterns and functional implications of rare germline variants across 12 cancer types von Lu, Charles, Xie, Mingchao, Wendl, Michael C., Wang, Jiayin, McLellan, Michael D., Leiserson, Mark D. M., Huang, Kuan-lin, Wyczalkowski, Matthew A., Jayasinghe, Reyka, Banerjee, Tapahsama, Ning, Jie, Tripathi, Piyush, Zhang, Qunyuan, Niu, Beifang, Ye, Kai, Schmidt, Heather K., Fulton, Robert S., McMichael, Joshua F., Batra, Prag, Kandoth, Cyriac, Bharadwaj, Maheetha, Koboldt, Daniel C., Miller, Christopher A., Kanchi, Krishna L., Eldred, James M., Larson, David E., Welch, John S., You, Ming, Ozenberger, Bradley A., Govindan, Ramaswamy, Walter, Matthew J., Ellis, Matthew J., Mardis, Elaine R., Graubert, Timothy A., Dipersio, John F., Ley, Timothy J., Wilson, Richard K., Goodfellow, Paul J., Raphael, Benjamin J., Chen, Feng, Johnson, Kimberly J., Parvin, Jeffrey D., Ding, Li

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Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia von Ley, Timothy J, Miller, Christopher, Ding, Li, Raphael, Benjamin J, Mungall, Andrew J, Robertson, A Gordon, Hoadley, Katherine, Triche, Jr, Timothy J, Laird, Peter W, Baty, Jack D, Fulton, Lucinda L, Fulton, Robert, Heath, Sharon E, Kalicki-Veizer, Joelle, Kandoth, Cyriac, Klco, Jeffery M, Koboldt, Daniel C, Kanchi, Krishna-Latha, Kulkarni, Shashikant, Lamprecht, Tamara L, Larson, David E, Lin, Ling, Lu, Charles, McLellan, Michael D, McMichael, Joshua F, Payton, Jacqueline, Schmidt, Heather, Spencer, David H, Tomasson, Michael H, Wallis, John W, Wartman, Lukas D, Watson, Mark A, Welch, John, Wendl, Michael C, Ally, Adrian, Balasundaram, Miruna, Birol, Inanc, Butterfield, Yaron, Chiu, Readman, Chu, Andy, Chuah, Eric, Chun, Hye-Jung, Corbett, Richard, Dhalla, Noreen, Guin, Ranabir, He, An, Hirst, Carrie, Hirst, Martin, Holt, Robert A, Jones, Steven, Karsan, Aly, Lee, Darlene, Li, Haiyan I, Marra, Marco A, Mayo, Michael, Moore, Richard A, Mungall, Karen, Parker, Jeremy, Pleasance, Erin, Plettner, Patrick, Schein, Jacquie, Stoll, Dominik, Swanson, Lucas, Tam, Angela, Thiessen, Nina, Varhol, Richard, Wye, Natasja, Zhao, Yongjun, Gabriel, Stacey, Getz, Gad, Sougnez, Carrie, Zou, Lihua, Leiserson, Mark D M, Vandin, Fabio, Wu, Hsin-Ta, Applebaum, Frederick, Baylin, Stephen B, Akbani, Rehan, Broom, Bradley M, Chen, Ken, Motter, Thomas C, Nguyen, Khanh, Weinstein, John N, Zhang, Nianziang, Ferguson, Martin L, Adams, Christopher, Black, Aaron, Bowen, Jay, Gastier-Foster, Julie, Grossman, Thomas, Lichtenberg, Tara, Wise, Lisa, Davidsen, Tanja, Demchok, John A, Shaw, Kenna R Mills, Sheth, Margi, Sofia, Heidi J, Yang, Liming, Downing, James R, Eley, Greg

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Integrated analysis of germline and somatic variants in ovarian cancer von Kanchi, Krishna L., Johnson, Kimberly J., Lu, Charles, McLellan, Michael D., Leiserson, Mark D. M., Wendl, Michael C., Zhang, Qunyuan, Koboldt, Daniel C., Xie, Mingchao, Kandoth, Cyriac, McMichael, Joshua F., Wyczalkowski, Matthew A., Larson, David E., Schmidt, Heather K., Miller, Christopher A., Fulton, Robert S., Spellman, Paul T., Mardis, Elaine R., Druley, Todd E., Graubert, Timothy A., Goodfellow, Paul J., Raphael, Benjamin J., Wilson, Richard K., Ding, Li

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Association of structural variation with cardiometabolic traits in Finns von Chen, Lei, Abel, Haley J., Das, Indraniel, Larson, David E., Ganel, Liron, Kanchi, Krishna L., Regier, Allison A., Young, Erica P., Kang, Chul Joo, Scott, Alexandra J., Chiang, Colby, Wang, Xinxin, Lu, Shuangjia, Christ, Ryan, Service, Susan K., Chiang, Charleston W.K., Havulinna, Aki S., Kuusisto, Johanna, Boehnke, Michael, Laakso, Markku, Palotie, Aarno, Ripatti, Samuli, Freimer, Nelson B., Locke, Adam E., Stitziel, Nathan O., Hall, Ira M.

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A Surprising Cross-Species Conservation in the Genomic Landscape of Mouse and Human Oral Cancer Identifies a Transcriptional Signature Predicting Metastatic Disease von ONKEN, Michael D, WINKLER, Ashley E, LEWIS, James S, MARDIS, Elaine R, UPPALURI, Ravindra, KANCHI, Krishna-Latha, CHALIVENDRA, Varun, LAW, Jonathan H, RICKERT, Charles G, KALLOGJERI, Dorina, JUDD, Nancy P, DUNN, Gavin P, PICCIRILLO, Jay F

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TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons von Zhao, Shuai, Lu, Jiuwei, Pan, Bo, Fan, Huitao, Byrum, Stephanie D., Xu, Chenxi, Kim, Arum, Guo, Yiran, Kanchi, Krishna L., Gong, Weida, Sun, Tongyu, Storey, Aaron J., Burkholder, Nathaniel T., Mackintosh, Samuel G., Kuhlers, Peyton C., Edmondson, Ricky D., Strahl, Brian D., Diao, Yarui, Tackett, Alan J., Raab, Jesse R., Cai, Ling, Song, Jikui, Wang, Gang Greg

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Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers von Pfefferle, Adam D, Agrawal, Yash N, Koboldt, Daniel C, Kanchi, Krishna L, Herschkowitz, Jason I, Mardis, Elaine R, Rosen, Jeffrey M, Perou, Charles M

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Rare Variation in TET2 Is Associated with Clinically Relevant Prostate Carcinoma in African Americans von Koboldt, Daniel C, Kanchi, Krishna L, Gui, Bin, Larson, David E, Fulton, Robert S, Isaacs, William B, Kraja, Aldi, Borecki, Ingrid B, Jia, Li, Wilson, Richard K, Mardis, Elaine R, Kibel, Adam S

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Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas von Griffith, Obi L., Chan, Szeman Ruby, Griffith, Malachi, Krysiak, Kilannin, Skidmore, Zachary L., Hundal, Jasreet, Allen, Julie A., Arthur, Cora D., Runci, Daniele, Bugatti, Mattia, Miceli, Alexander P., Schmidt, Heather, Trani, Lee, Kanchi, Krishna-Latha, Miller, Christopher A., Larson, David E., Fulton, Robert S., Vermi, William, Wilson, Richard K., Schreiber, Robert D., Mardis, Elaine R.

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Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences von Ganel, Liron, Chen, Lei, Christ, Ryan, Vangipurapu, Jagadish, Young, Erica, Das, Indraniel, Kanchi, Krishna, Larson, David, Regier, Allison, Abel, Haley, Kang, Chul Joo, Scott, Alexandra, Havulinna, Aki, Chiang, Charleston W K, Service, Susan, Freimer, Nelson, Palotie, Aarno, Ripatti, Samuli, Kuusisto, Johanna, Boehnke, Michael, Laakso, Markku, Locke, Adam, Stitziel, Nathan O, Hall, Ira M

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Abstract 1863: Inactivation of RASA1 promotes melanoma tumorigenesis via R-Ras activation von Hill, Kristen S., Sung, Hyeran, Kanchi, Krishna L., Messina, Jane L., Lee, Ji-Hyun, Kim, Youngchul, Ding, Li, Wilson, Richard K., Weber, Jeffrey S., Kim, Minjung

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Correction: Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases von Hoadley, Katherine A, Siegel, Marni B, Kanchi, Krishna L, Miller, Christopher A, Ding, Li, Zhao, Wei, He, Xiaping, Parker, Joel S, Wendl, Michael C, Fulton, Robert S, Demeter, Ryan T, Wilson, Richard K, Carey, Lisa A, Perou, Charles M, Mardis, Elaine R

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Author Correction: Exome sequencing of Finnish isolates enhances rare-variant association power von Locke, Adam E., Steinberg, Karyn Meltz, Chiang, Charleston W. K., Service, Susan K., Havulinna, Aki S., Stell, Laurel, Pirinen, Matti, Abel, Haley J., Chiang, Colby C., Fulton, Robert S., Jackson, Anne U., Kang, Chul Joo, Kanchi, Krishna L., Koboldt, Daniel C., Larson, David E., Nelson, Joanne, Nicholas, Thomas J., Pietilä, Arto, Ramensky, Vasily, Ray, Debashree, Scott, Laura J., Stringham, Heather M., Vangipurapu, Jagadish, Welch, Ryan, Yajnik, Pranav, Yin, Xianyong, Eriksson, Johan G., Ala-Korpela, Mika, Järvelin, Marjo-Riitta, Männikkö, Minna, Laivuori, Hannele, Dutcher, Susan K., Stitziel, Nathan O., Wilson, Richard K., Hall, Ira M., Sabatti, Chiara, Palotie, Aarno, Salomaa, Veikko, Laakso, Markku, Ripatti, Samuli, Boehnke, Michael, Freimer, Nelson B.

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