Human genetics as a foundation for innovative drug development von Kamb, Alexander, Harper, Sean, Stefansson, Kari

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Robust In Vitro Pharmacology of Tmod, a Synthetic Dual-Signal Integrator for Cancer Cell Therapy von Manry, Diane, Bolanos, Kristian, DiAndreth, Breanna, Mock, Jee-Young, Kamb, Alexander

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Cancer T-cell therapy: building the foundation for a cure [version 2; peer review: 3 approved] von Kamb, Alexander, Go, William Y

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Geometric parameters that affect the behavior of logic-gated CAR T cells von Partin, Alexander C, Bruno, Richele, Shafaattalab, Sanam, Vander Mause, Erica, Winters, Aaron, Daris, Mark, Gahrs, Casey, Jette, Claudia A, DiAndreth, Breanna, Sandberg, Mark L, Hamburger, Agnes E, Kamb, Alexander, Riley, Timothy P

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A multivariate, quantitative assay that disentangles key kinetic parameters of primary human T cell function in vitro von Huang, Grace L, Nampe, Daniel P, Yi, Jason, Gabrelow, Grant B, Negri, Kathleen R, Kamb, Alexander, Xu, Han

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Mesothelin-specific CAR-T cell therapy that incorporates an HLA-gated safety mechanism selectively kills tumor cells von Tokatlian, Talar, Asuelime, Grace E, Mock, Jee-Young, DiAndreth, Breanna, Sharma, Shruti, Toledo Warshaviak, Dora, Daris, Mark E, Bolanos, Kristian, Luna, Breanna L, Naradikian, Martin S, Deshmukh, Kiran, Hamburger, Agnes E, Kamb, Alexander

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Publishing confirming and non-confirming data [version 1; peer review: not peer reviewed] von Alberts, Bruce, Kamb, Alexander

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What's wrong with our cancer models? von Kamb, Alexander

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Cancer T-cell therapy: building the foundation for a cure [version 1; peer review: 1 approved, 2 approved with reservations] von Kamb, Alexander, Go, William Y

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Sphingosine kinase activity is not required for tumor cell viability von Rex, Karen, Jeffries, Shawn, Brown, Matthew L, Carlson, Timothy, Coxon, Angela, Fajardo, Flordeliza, Frank, Brendon, Gustin, Darin, Kamb, Alexander, Kassner, Paul D, Li, Shyun, Li, Yihong, Morgenstern, Kurt, Plant, Matthew, Quon, Kim, Ruefli-Brasse, Astrid, Schmidt, Joanna, Swearingen, Elissa, Walker, Nigel, Wang, Zhulun, Watson, J E Vivienne, Wickramasinghe, Dineli, Wong, Mariwil, Xu, Guifen, Wesche, Holger

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NOT gated T cells that selectively target EGFR and other widely expressed tumor antigens von Oh, Julyun, Kirsh, Charles, Hsin, Jing-Ping, Radecki, Kelly C., Zampieri, Alexandre, Manry, Diane, Ando, Yuta, Miller, Sara, Chan, Jamie, McLeod, Ethan, Cunningham, Kathleen M., Wong, Lu Min, Xu, Han, Kamb, Alexander

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HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen von Mock, Jee-Young, Winters, Aaron, Riley, Timothy P., Bruno, Richele, Naradikian, Martin S., Sharma, Shruti, Jette, Claudia A., Elshimali, Ryan, Gahrs, Casey, Toledo-Warshaviak, Dora, West, Anthony P., Kamb, Alexander, Hamburger, Agnes E.

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Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer von Blum, Roy, Gupta, Rashmi, Burger, Patricia E, Ontiveros, Christopher S, Salm, Sarah N, Xiong, Xiaozhong, Kamb, Alexander, Wesche, Holger, Marshall, Lisa, Cutler, Gene, Wang, Xiangyun, Zavadil, Jiri, Moscatelli, David, Wilson, E Lynette

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Why is cancer drug discovery so difficult? von Kamb, Alexander, Wee, Susan, Lengauer, Christoph

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115 Engineered T cells directed at tumors with defined allelic loss von Hamburger, Agi, DiAndreth, Breanna, Cui, Jiajia, Daris, Mark, Munguia, Melanie, Deshmukh, Kiran, Mock, Jee-Young, Asuelime, Grace, Lim, Emily, Kreke, Michelle, Tokatlian, Talar, Kamb, Alexander

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A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types von Kamb, Alexander, Gruis, Nelleke A., Weaver-Feldhaus, Jane, Liu, Qingyun, Harshman, Keith, Tavtigian, Sean V., Stockert, Elisabeth, Day, Rufus S., Johnson, Bruce E., Skolnick, Mark H.

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Next-Generation Sequencing and Its Potential Impact von Kamb, Alexander

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Molecular signatures of the primitive prostate stem cell niche reveal novel mesenchymal-epithelial signaling pathways von Blum, Roy, Gupta, Rashmi, Burger, Patricia E, Ontiveros, Christopher S, Salm, Sarah N, Xiong, Xiaozhong, Kamb, Alexander, Wesche, Holger, Marshall, Lisa, Cutler, Gene, Wang, Xiangyun, Zavadil, Jiri, Moscatelli, David, Wilson, E Lynette

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The Tmod cellular logic gate as a solution for tumor-selective immunotherapy von DiAndreth, Breanna, Hamburger, Agnes E., Xu, Han, Kamb, Alexander

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At a crossroads in oncology von Kamb, Alexander

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