C-Terminal Modifications of Histidyl-N-benzylglycinamides To Give Improved Inhibition of Ras Farnesyltransferase, Cellular Activity, and Anticancer Activity in Mice von McNamara, Dennis J, Dobrusin, Ellen, Leonard, Daniele M, Shuler, Kevon R, Kaltenbronn, James S, Quin, John, Bur, Scott, Thomas, Charles E, Doherty, Annette M, Scholten, Jeffrey D, Zimmerman, Karen K, Gibbs, Barbara S, Gowan, Richard C, Latash, Michael P, Leopold, Wilbur R, Przybranowski, Sally A, Sebolt-Leopold, Judith S

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Renin inhibitors containing isosteric replacements of the amide bond connecting the P3 and P2 sites von Kaltenbronn, James S, Hudspeth, J. P, Lunney, E. A, Michniewicz, B. M, Nicolaides, E. D, Repine, J. T, Roark, W. H, Stier, M. A, Tinney, F. J

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Synthesis and structure activity relationships of potent new angiotensin converting enzyme inhibitors containing saturated bicyclic amino acids von Blankley, C. J, Kaltenbronn, J. S, DeJohn, D. E, Werner, A, Bennett, L. R, Bobowski, G, Krolls, U, Johnson, D. R, Pearlman, W. M

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Renin inhibitors containing .alpha.-heteroatom amino acids as P2 residues von Repine, Joseph T, Kaltenbronn, James S, Doherty, Annette M, Hamby, James M, Himmelsbach, Richard J, Kornberg, Brian E, Taylor, Michael D, Lunney, ELizabeth A, Humblet, Christine

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Renin inhibitors containing esters at the P2-position. Oral activity in a derivative of methyl aminomalonate von Repine, Joseph T, Himmelsbach, Richard J, Hodges, John C, Kaltenbronn, James S, Sircar, Ila, Skeean, Richard W, Brennan, Sean T, Hurley, Timothy R, Lunney, Elizabeth

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Modified di- and tripeptides of the C-terminal portion of oxytocin and vasopressin as possible cognition activation agents von Nicolaides, E. D, Tinney, F. J, Kaltenbronn, J. S, Repine, J. T, DeJohn, D. A, Lunney, E. A, Roark, W. H

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Design and synthesis of potent, selective, and orally active fluorine-containing renin inhibitors von Doherty, Annette M, Sircar, Ila, Kornberg, Brian E, Quin, John, Winters, R. Thomas, Kaltenbronn, James S, Taylor, Michael D, Batley, Brian L, Rapundalo, Stephen R

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Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors von Lunney, Elizabeth A, Hamilton, Harriet W, Hodges, John C, Kaltenbronn, James S, Repine, Joseph T, Badasso, Mohammed, Cooper, Jon B, Dealwis, Chris, Wallace, Bonnie A

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Design and Synthesis of Renin Inhibitors: Incorporation of Transition-State Isostere Side Chains That Span from the S1 to the S3 Binding Pockets and Examination of P3-Modified Reni... von Shahripour, Aurash, Kaltenbronn, James S, Lunney, Elizabeth A, Steinbaugh, Bruce A, Hamby, James M, Hamilton, Harriet W, Sawyer, Tomi K, Humblet, Christine, Doherty, Annette M

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Anti-writhing activity of some peptides related to neurotensin and tuftsin von NICOLAIDES, E.D., LUNNEY, E.A., KALTENBRONN, J.S., WILEY, J.N., DOWNS, D.A.

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Evaluation of Physicochemical Parameters Important to the Oral Bioavailability of Peptide-like Compounds: Implications for the Synthesis of Renin Inhibitors von Hamilton, Harriet W, Steinbaugh, Bruce A, Stewart, Barbra H, Chan, O. Helen, Schmid, Heidi L, Schroeder, Richard, Ryan, Michael J, Keiser, Joan, Taylor, Michael D

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Benzofuran derivatives as ET A-selective, non-peptide endothelin antagonists von Kaltenbronn, JS, Quin, J, Reisdorph, BR, Klutchko, S, Reynolds, EE, Welch, KM, Flynn, MA, Doherty, AM

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Benzofuran derivatives as ETA-selective, non-peptide endothelin antagonists von KALTENBRONN, J. S, QUIN, J. III, REISDORPH, B. R, KLUTCHKO, S, REYNOLDS, E. E, WELCH, K. M, FLYNN, M. A, DOHERTY, A. M

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Structure-activity relationships of the potent combined endothelin-A/endothelin-B receptor antagonist Ac-DDip16-Leu-Asp-Ile-Ile-Trp21 : development of endothelin-B receptor selecti... von CODY, W. L, HE, J. X, WELCH, K. M, REYNOLDS, E. E, DOHERTY, A. M, DEPUE, P. L, WAITE, L. A, LEONARD, D. M, SEFLER, A. M, KALTENBRONN, J. S, HALEEN, S. J, WALKER, D. M, FLYNN, M. A

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New inhibitors of human renin that contain novel replacements at the P2 site von Doherty, Annette M, Kaltenbronn, James S, Hudspeth, James P, Repine, Joseph T, Roark, William H, Sircar, Ila, Tinney, Frank J, Connolly, Cleo J, Hodges, John C

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SEMISYNTHETIC PENICILLINS AND CEPHALOSPORINS CONTAINING THE SUBSTITUTED 6-VINYL-1, 2-DIHYDRO-2-OXO- AND 1, 4-DIHYDRO-4-OXO-3-PYRIDINECARBOXYLIC ACID SIDE CHAINS: SYNTHESIS AND STRU... von DEJOHN, DANA, DOMAGALA, JOHN M., HASKELL, THEODORE H., HEIFETZ, CARL L., HUANG, GIN-GUEI, KALTENBRONN, JAMES S., KROLLS, ULDIS

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553. The absolute configuration of rotenone von Büchi, G., Crombie, L., Godin, P. J., Kaltenbronn, J. S., Siddalingaiah, K. S., Whiting, D. A.

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Design and synthesis of renin inhibitors : incoporation of transition-state isostere side chain that span from the S1 to the S3 binding pockets and examintion of P3-modified renin... von PLUMMER, M. S, AURASH SHAHRIPOUR, TAYLOR, M. D, HINGORANI, G, BATLEY, B. L, RAPUNDALO, S. T, KALTENBRONN, J. S, LUNNEY, E. A, STEINBAUGH, B. A, HAMBY, J. M, HAMILTON, H. W, SAWYER, T. K, HUMBLET, C, DOHERTY, A. M

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4- and 5-Aryl-l-naphthaleneacetic acids as antiinflammatory agents von Kaltenbronn, J S

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New inhibitors of human renin that contain novel replacements at the P sub(2) site von Doherty, A M, Kaltenbronn, J S, Hudspeth, J P, Repine, J T, Roark, W H, Sircar, I, Tinney, F J, Connolly, C J, Hodges, J C

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