Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation von Khetan, Shubham, Kales, Susan, Kursawe, Romy, Jillette, Alexandria, Ulirsch, Jacob C., Reilly, Steven K., Ucar, Duygu, Tewhey, Ryan, Stitzel, Michael L.

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A systematic strategy for identifying causal single nucleotide polymorphisms and their target genes on Juvenile arthritis risk haplotypes von Jiang, Kaiyu, Liu, Tao, Kales, Susan, Tewhey, Ryan, Kim, Dongkyeong, Park, Yungki, Jarvis, James N

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Whole-genome functional characterization of RE1 silencers using a modified massively parallel reporter assay von Mouri, Kousuke, Dewey, Hannah B., Castro, Rodrigo, Berenzy, Daniel, Kales, Susan, Tewhey, Ryan

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High-throughput discovery of novel developmental phenotypes von Dickinson, Mary E., Flenniken, Ann M., Ji, Xiao, Teboul, Lydia, Wong, Michael D., White, Jacqueline K., Meehan, Terrence F., Weninger, Wolfgang J., Westerberg, Henrik, Adissu, Hibret, Baker, Candice N., Bower, Lynette, Brown, James M., Caddle, L. Brianna, Chiani, Francesco, Clary, Dave, Cleak, James, Daly, Mark J., Denegre, James M., Doe, Brendan, Dolan, Mary E., Edie, Sarah M., Fuchs, Helmut, Gailus-Durner, Valerie, Galli, Antonella, Gambadoro, Alessia, Gallegos, Juan, Guo, Shiying, Horner, Neil R., Hsu, Chih-Wei, Johnson, Sara J., Kalaga, Sowmya, Keith, Lance C., Lanoue, Louise, Lawson, Thomas N., Lek, Monkol, Mark, Manuel, Marschall, Susan, Mason, Jeremy, McElwee, Melissa L., Newbigging, Susan, Nutter, Lauryl M. J., Peterson, Kevin A., Ramirez-Solis, Ramiro, Rowland, Douglas J., Ryder, Edward, Samocha, Kaitlin E., Seavitt, John R., Selloum, Mohammed, Szoke-Kovacs, Zsombor, Tamura, Masaru, Trainor, Amanda G., Tudose, Ilinca, Wakana, Shigeharu, Warren, Jonathan, Wendling, Olivia, West, David B., Wong, Leeyean, Yoshiki, Atsushi, Wurst, Wolfgang, MacArthur, Daniel G., Tocchini-Valentini, Glauco P., Gao, Xiang, Flicek, Paul, Bradley, Allan, Skarnes, William C., Justice, Monica J., Parkinson, Helen E., Moore, Mark, Wells, Sara, Braun, Robert E., Svenson, Karen L., de Angelis, Martin Hrabe, Herault, Yann, Mohun, Tim, Mallon, Ann-Marie, Henkelman, R. Mark, Brown, Steve D. M., Adams, David J., Lloyd, K. C. Kent, McKerlie, Colin, Beaudet, Arthur L., Bućan, Maja, Murray, Stephen A.

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Three linked variants have opposing regulatory effects on isovaleryl-CoA dehydrogenase gene expression von Brown, Elizabeth A, Kales, Susan, Boyle, Michael James, Vitti, Joseph, Kotliar, Dylan, Schaffner, Steve, Tewhey, Ryan, Sabeti, Pardis C

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A resource of targeted mutant mouse lines for 5,061 genes von Birling, Marie-Christine, Yoshiki, Atsushi, Adams, David J., Ayabe, Shinya, Beaudet, Arthur L., Bottomley, Joanna, Bradley, Allan, Brown, Steve D. M., Bürger, Antje, Bushell, Wendy, Chiani, Francesco, Chin, Hsian-Jean Genie, Christou, Skevoulla, Codner, Gemma F., DeMayo, Francesco J., Dickinson, Mary E., Doe, Brendan, Donahue, Leah Rae, Fray, Martin D., Gambadoro, Alessia, Gao, Xiang, Gertsenstein, Marina, Gomez-Segura, Alba, Goodwin, Leslie O., Heaney, Jason D., Hérault, Yann, de Angelis, Martin Hrabe, Jiang, Si-Tse, Justice, Monica J., Kasparek, Petr, King, Ruairidh E., Kühn, Ralf, Lee, Ho, Lee, Young Jae, Liu, Zhiwei, Lloyd, K. C. Kent, Lorenzo, Isabel, Mallon, Ann-Marie, McKerlie, Colin, Meehan, Terrence F., Fuentes, Violeta Munoz, Newman, Stuart, Nutter, Lauryl M. J., Oh, Goo Taeg, Pavlovic, Guillaume, Ramirez-Solis, Ramiro, Rosen, Barry, Ryder, Edward J., Santos, Luis A., Schick, Joel, Seavitt, John R., Sedlacek, Radislav, Seisenberger, Claudia, Seong, Je Kyung, Skarnes, William C., Sorg, Tania, Steel, Karen P., Tamura, Masaru, Tocchini-Valentini, Glauco P., Wang, Chi-Kuang Leo, Wardle-Jones, Hannah, Wattenhofer-Donzé, Marie, Wells, Sara, Wiles, Michael V., Willis, Brandon J., Wood, Joshua A., Wurst, Wolfgang, Xu, Ying, Teboul, Lydia, Murray, Stephen A.

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Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR–FlowFISH von Reilly, Steven K., Gosai, Sager J., Gutierrez, Alan, Mackay-Smith, Ava, Ulirsch, Jacob C., Kanai, Masahiro, Mouri, Kousuke, Berenzy, Daniel, Kales, Susan, Butler, Gina M., Gladden-Young, Adrianne, Bhuiyan, Redwan M., Stitzel, Michael L., Finucane, Hilary K., Sabeti, Pardis C., Tewhey, Ryan

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211-OR: Massively Parallel Characterization of Thousands of Type 2 Diabetes–Associated Variants in Multiple Cell Types Nominates Candidate Causal Regulatory Alleles and Mechanisms... von KOTHARI, MADHAV, BHUIYAN, REDWAN M., ULIRSCH, JACOB C., DEWEY, HANNAH, NERURKAR, NIKETA, KURSAWE, ROMY, KALES, SUSAN, BERENZY, DANIEL, TEWHEY, RYAN, STITZEL, MICHAEL L.

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Machine-guided design of cell-type-targeting cis-regulatory elements von Gosai, Sager J., Castro, Rodrigo I., Fuentes, Natalia, Butts, John C., Mouri, Kousuke, Alasoadura, Michael, Kales, Susan, Nguyen, Thanh Thanh L., Noche, Ramil R., Rao, Arya S., Joy, Mary T., Sabeti, Pardis C., Reilly, Steven K., Tewhey, Ryan

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Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines von Elrick, Hillary, Peterson, Kevin A., Willis, Brandon J., Lanza, Denise G., Acar, Elif F., Ryder, Edward J., Teboul, Lydia, Kasparek, Petr, Birling, Marie-Christine, Adams, David J., Bradley, Allan, Braun, Robert E., Brown, Steve D., Caulder, Adam, Codner, Gemma F., DeMayo, Francesco J., Dickinson, Mary E., Doe, Brendan, Duddy, Graham, Gertsenstein, Marina, Goodwin, Leslie O., Hérault, Yann, Lintott, Lauri G., Lloyd, K. C. Kent, Lorenzo, Isabel, Mackenzie, Matthew, Mallon, Ann-Marie, McKerlie, Colin, Parkinson, Helen, Ramirez-Solis, Ramiro, Seavitt, John R., Sedlacek, Radislav, Skarnes, William C., Smedley, Damien, Wells, Sara, White, Jacqueline K., Wood, Joshua A., Murray, Stephen A., Heaney, Jason D., Nutter, Lauryl M. J.

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Author Correction: Direct characterization of cis-regulatory elements and functional dissection of complex genetic associations using HCR–FlowFISH von Reilly, Steven K., Gosai, Sager J., Gutierrez, Alan, Mackay-Smith, Ava, Ulirsch, Jacob C., Kanai, Masahiro, Mouri, Kousuke, Berenzy, Daniel, Kales, Susan, Butler, Gina M., Gladden-Young, Adrianne, Bhuiyan, Redwan M., Stitzel, Michael L., Finucane, Hilary K., Sabeti, Pardis C., Tewhey, Ryan

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Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever von Kotliar, Dylan, Raju, Siddharth, Tabrizi, Shervin, Odia, Ikponmwosa, Goba, Augustine, Momoh, Mambu, Sandi, John Demby, Nair, Parvathy, Phelan, Eric, Tariyal, Ridhi, Eromon, Philomena E., Mehta, Samar, Robles-Sikisaka, Refugio, Siddle, Katherine J., Stremlau, Matt, Jalloh, Simbirie, Gire, Stephen K., Winnicki, Sarah, Chak, Bridget, Schaffner, Stephen F., Pauthner, Matthias, Karlsson, Elinor K., Chapin, Sarah R., Kennedy, Sharon G., Branco, Luis M., Kanneh, Lansana, Vitti, Joseph J., Broodie, Nisha, Gladden-Young, Adrianne, Omoniwa, Omowunmi, Jiang, Pan-Pan, Yozwiak, Nathan, Heuklom, Shannon, Moses, Lina M., Akpede, George O., Asogun, Danny A., Rubins, Kathleen, Kales, Susan, Happi, Anise N., Iruolagbe, Christopher O., Dic-Ijiewere, Mercy, Iraoyah, Kelly, Osazuwa, Omoregie O., Okonkwo, Alexander K., Kunz, Stefan, McCormick, Joseph B., Khan, S. Humarr, Honko, Anna N., Lander, Eric S., Oldstone, Michael B. A., Hensley, Lisa, Folarin, Onikepe A., Okogbenin, Sylvanus A., Günther, Stephan, Ollila, Hanna M., Tewhey, Ryan, Okokhere, Peter O., Schieffelin, John S., Andersen, Kristian G., Reilly, Steven K., Grant, Donald S., Garry, Robert F., Barnes, Kayla G., Happi, Christian T., Sabeti, Pardis C.

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Identification of genes required for eye development by high-throughput screening of mouse knockouts von Moore, Bret A., Leonard, Brian C., Sebbag, Lionel, Edwards, Sydney G., Cooper, Ann, Imai, Denise M., Straiton, Ewan, Santos, Luis, Reilly, Christopher, Griffey, Stephen M., Bower, Lynette, Clary, David, Mason, Jeremy, Roux, Michel J., Meziane, Hamid, Herault, Yann, McKerlie, Colin, Flenniken, Ann M., Nutter, Lauryl M. J., Berberovic, Zorana, Owen, Celeste, Newbigging, Susan, Adissu, Hibret, Eskandarian, Mohammed, Hsu, Chih-Wei, Kalaga, Sowmya, Udensi, Uchechukwu, Asomugha, Chinwe, Bohat, Ritu, Gallegos, Juan J., Seavitt, John R., Heaney, Jason D., Beaudet, Arthur L., Dickinson, Mary E., Justice, Monica J., Philip, Vivek, Kumar, Vivek, Svenson, Karen L., Braun, Robert E., Wells, Sara, Cater, Heather, Stewart, Michelle, Clementson-Mobbs, Sharon, Joynson, Russell, Gao, Xiang, Suzuki, Tomohiro, Wakana, Shigeharu, Smedley, Damian, Seong, J. K, Tocchini-Valentini, Glauco, Moore, Mark, Fletcher, Colin, Karp, Natasha, Ramirez-Solis, Ramiro, White, Jacqueline K., de Angelis, Martin Hrabe, Wurst, Wolfgang, Thomasy, Sara M., Flicek, Paul, Parkinson, Helen, Brown, Steve D. M., Meehan, Terrence F., Nishina, Patsy M., Murray, Stephen A., Krebs, Mark P., Mallon, Ann-Marie, Lloyd, K. C. Kent, Murphy, Christopher J., Moshiri, Ala

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Synthetic DNA spike-ins (SDSIs) enable sample tracking and detection of inter-sample contamination in SARS-CoV-2 sequencing workflows von Lagerborg, Kim A., Normandin, Erica, Bauer, Matthew R., Adams, Gordon, Figueroa, Katherine, Loreth, Christine, Gladden-Young, Adrianne, Shaw, Bennett M., Pearlman, Leah R., Berenzy, Daniel, Dewey, Hannah B., Kales, Susan, Dobbins, Sabrina T., Shenoy, Erica S., Hooper, David, Pierce, Virginia M., Zachary, Kimon C., Park, Daniel J., MacInnis, Bronwyn L., Tewhey, Ryan, Lemieux, Jacob E., Sabeti, Pardis C., Reilly, Steven K., Siddle, Katherine J.

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Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts von Moore, Bret A, Leonard, Brian C, Sebbag, Lionel, Edwards, Sydney G, Cooper, Ann, Imai, Denise M, Straiton, Ewan, Santos, Luis, Reilly, Christopher, Griffey, Stephen M, Bower, Lynette, Clary, David, Mason, Jeremy, Roux, Michel J, Meziane, Hamid, Herault, Yann, McKerlie, Colin, Flenniken, Ann M, Nutter, Lauryl M J, Berberovic, Zorana, Owen, Celeste, Newbigging, Susan, Adissu, Hibret, Eskandarian, Mohammed, Hsu, Chih-Wei, Kalaga, Sowmya, Udensi, Uchechukwu, Asomugha, Chinwe, Bohat, Ritu, Gallegos, Juan J, Seavitt, John R, Heaney, Jason D, Beaudet, Arthur L, Dickinson, Mary E, Justice, Monica J, Philip, Vivek, Kumar, Vivek, Svenson, Karen L, Braun, Robert E, Wells, Sara, Cater, Heather, Stewart, Michelle, Clementson-Mobbs, Sharon, Joynson, Russell, Gao, Xiang, Suzuki, Tomohiro, Wakana, Shigeharu, Smedley, Damian, Seong, J K, Tocchini-Valentini, Glauco, Moore, Mark, Fletcher, Colin, Karp, Natasha, Ramirez-Solis, Ramiro, White, Jacqueline K, de Angelis, Martin Hrabe, Wurst, Wolfgang, Thomasy, Sara M, Flicek, Paul, Parkinson, Helen, Brown, Steve D M, Meehan, Terrence F, Nishina, Patsy M, Murray, Stephen A, Krebs, Mark P, Mallon, Ann-Marie, Kent Lloyd, K C, Murphy, Christopher J, Moshiri, Ala

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Discovery of Wall Teichoic Acid Inhibitors as Potential Anti-MRSA β-Lactam Combination Agents von Wang, Hao, Gill, Charles J., Lee, Sang H., Mann, Paul, Zuck, Paul, Meredith, Timothy C., Murgolo, Nicholas, She, Xinwei, Kales, Susan, Liang, Lianzhu, Liu, Jenny, Wu, Jin, Santa Maria, John, Su, Jing, Pan, Jianping, Hailey, Judy, Mcguinness, Debra, Tan, Christopher M., Flattery, Amy, Walker, Suzanne, Black, Todd, Roemer, Terry

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Discovery of Novel Wall Teichoic Acid Inhibitors as Effective anti-MRSA β-lactam Combination Agents von Wang, Hao, Gill, Charles J., Lee, Sang H., Mann, Paul, Zuck, Paul, Meredith, Timothy C., Murgolo, Nicholas, She, Xinwei, Kales, Susan, Liang, Lianzhu, Liu, Jenny, Wu, Jin, Maria, John Santa, Su, Jing, Pan, Jianping, Hailey, Judy, Mcguinness, Debra, Tan, Christopher M., Flattery, Amy, Walker, Suzanne, Black, Todd, Roemer, Terry

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Prevention of HIV-1 Infection with Early Antiretroviral Therapy von Cohen, Myron S, Chen, Ying Q, McCauley, Marybeth, Gamble, Theresa, Hosseinipour, Mina C, Kumarasamy, Nagalingeswaran, Hakim, James G, Kumwenda, Johnstone, Grinsztejn, Beatriz, Pilotto, Jose H.S, Godbole, Sheela V, Mehendale, Sanjay, Chariyalertsak, Suwat, Santos, Breno R, Mayer, Kenneth H, Hoffman, Irving F, Eshleman, Susan H, Piwowar-Manning, Estelle, Wang, Lei, Makhema, Joseph, Mills, Lisa A, de Bruyn, Guy, Sanne, Ian, Eron, Joseph, Gallant, Joel, Havlir, Diane, Swindells, Susan, Ribaudo, Heather, Elharrar, Vanessa, Burns, David, Taha, Taha E, Nielsen-Saines, Karin, Celentano, David, Essex, Max, Fleming, Thomas R

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Implementing goals of care conversations with veterans in VA long-term care setting: a mixed methods protocol von Sales, Anne E, Ersek, Mary, Intrator, Orna K, Levy, Cari, Carpenter, Joan G, Hogikyan, Robert, Kales, Helen C, Landis-Lewis, Zach, Olsan, Tobie, Miller, Susan C, Montagnini, Marcos, Periyakoil, Vyjeyanthi S, Reder, Sheri

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Correction to: Implementing goals of care conversations with veterans in VA long-term care setting: a mixed methods protocol von Sales, Anne E, Ersek, Mary, Intrator, Orna K, Levy, Cari, Carpenter, Joan G, Hogikyan, Robert, Kales, Helen C, Landis-Lewis, Zach, Olsan, Tobie, Miller, Susan C, Montagnini, Marcos, Periyakoil, Vyjeyanthi S, Reder, Sheri

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