Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation von Pengelly, Ana Raquel, Kalb, Reinhard, Finkl, Katja, Müller, Jürg

Volltext

Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression von Kalb, Reinhard, Latwiel, Sebastian, Baymaz, H Irem, Jansen, Pascal W T C, Müller, Christoph W, Vermeulen, Michiel, Müller, Jürg

Volltext

BRCA1 Is a Histone-H2A-Specific Ubiquitin Ligase von Kalb, Reinhard, Mallery, Donna L., Larkin, Conor, Huang, Jeffrey T.J., Hiom, Kevin

Volltext

Human RAD50 Deficiency in a Nijmegen Breakage Syndrome-like Disorder von Waltes, Regina, Kalb, Reinhard, Gatei, Magtouf, Kijas, Amanda W., Stumm, Markus, Sobeck, Alexandra, Wieland, Britta, Varon, Raymonda, Lerenthal, Yaniv, Lavin, Martin F., Schindler, Detlev, Dörk, Thilo

Volltext

A novel classification of hematologic conditions in patients with Fanconi anemia von Behrens, Yvonne Lisa, Göhring, Gudrun, Bawadi, Randa, Cöktü, Sümeyye, Reimer, Christina, Hoffmann, Beatrice, Sänger, Birte, Käfer, Simon, Thol, Felicitas, Erlacher, Miriam, Niemeyer, Charlotte M, Baumann, Irith, Kalb, Reinhard, Schindler, Detlev, Kratz, Christian Peter

Volltext

Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer von Seal, Sheila, Barker, Karen, Ariffin, Hany, Rahman, Nazneen, Hanks, Sandra, Hanenberg, Helmut, Reid, Sarah, Freund, Marcel, Kelly, Patrick, Auerbach, Arleen D, Wurm, Melanie, Tischkowitz, Marc, Batish, Sat Dev, Mathew, Christopher G, Yetgin, Sevgi, Neveling, Kornelia, Lach, Francis P, Schindler, Detlev, Kalb, Reinhard, Neitzel, Heidemarie

Volltext

Germline biallelic BRCA2 pathogenic variants and medulloblastoma: an international cohort study von Kastellan, Svenja, Kalb, Reinhard, Sajjad, Bia, McReynolds, Lisa J, Giri, Neelam, Samuel, David, Milde, Till, Elbracht, Miriam, Holzhauer, Susanne, Niewisch, Marena R, Kratz, Christian P

Volltext

The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia von Levran, Orna, Milton, Kelly L, Henry, Rashida T, Neveling, Kornelia, Ott, Jurg, Attwooll, Claire, Rio, Paula, Schindler, Detlev, Petrini, John, Batish, Sat Dev, Auerbach, Arleen D, Velleuer, Eunike, Kalb, Reinhard, Barral, Sandra, Hanenberg, Helmut

Volltext

ATM Protein-dependent Phosphorylation of Rad50 Protein Regulates DNA Repair and Cell Cycle Control von Gatei, Magtouf, Jakob, Burkhard, Chen, Philip, Kijas, Amanda W., Becherel, Olivier J., Gueven, Nuri, Birrell, Geoff, Lee, Ji-Hoon, Paull, Tanya T., Lerenthal, Yaniv, Fazry, Shazrul, Taucher-Scholz, Gisela, Kalb, Reinhard, Schindler, Detlev, Waltes, Regina, Dörk, Thilo, Lavin, Martin F.

Volltext

Disease and mutation: correlations coming to fruition von Schindler, Detlev, Kalb, Reinhard

Volltext

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway von Ling, Chen, Ishiai, Masamichi, Ali, Abdullah Mahmood, Medhurst, Annette L, Neveling, Kornelia, Kalb, Reinhard, Yan, Zhijiang, Xue, Yutong, Oostra, Anneke B, Auerbach, Arleen D, Hoatlin, Maureen E, Schindler, Detlev, Joenje, Hans, de Winter, Johan P, Takata, Minoru, Meetei, Amom Ruhikanta, Wang, Weidong

Volltext

PR-DUB preserves Polycomb repression by preventing excessive accumulation of H2Aub1, an antagonist of chromatin compaction von Bonnet, Jacques, Boichenko, Iulia, Kalb, Reinhard, Le Jeune, Mathilde, Maltseva, Svetlana, Pieropan, Mattia, Finkl, Katja, Fierz, Beat, Müller, Jürg

Volltext

Cancer in Children With Fanconi Anemia and Ataxia-Telangiectasia-A Nationwide Register-Based Cohort Study in Germany von Dutzmann, Christina M, Spix, Claudia, Popp, Isabell, Kaiser, Melanie, Erdmann, Friederike, Erlacher, Miriam, Dörk, Thilo, Schindler, Detlev, Kalb, Reinhard, Kratz, Christian P

Volltext

Inhibition of USP28 overcomes Cisplatin-resistance of squamous tumors by suppression of the Fanconi anemia pathway von Prieto-Garcia, Cristian, Hartmann, Oliver, Reissland, Michaela, Fischer, Thomas, Maier, Carina R., Rosenfeldt, Mathias, Schülein-Völk, Christina, Klann, Kevin, Kalb, Reinhard, Dikic, Ivan, Münch, Christian, Diefenbacher, Markus E.

Volltext

The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness von Hasler, Daniele, Meduri, Rajyalakshmi, Bąk, Maciej, Lehmann, Gerhard, Heizinger, Leonhard, Wang, Xin, Li, Zhi-Tong, Sement, François M., Bruckmann, Astrid, Dock-Bregeon, Anne-Catherine, Merkl, Rainer, Kalb, Reinhard, Grauer, Eva, Kunstmann, Erdmute, Zavolan, Mihaela, Liu, Mo-Fang, Fischer, Utz, Meister, Gunter

Volltext

Lack of Sensitivity of Primary Fanconi's Anemia Fibroblasts to UV and Ionizing Radiation von Kalb, Reinhard, Duerr, Michael, Wagner, Matthias, Herterich, Sabine, Gross, Michaela, Digweed, Martin, Joenje, Hans, Hoehn, Holger, Schindler, Detlev

Volltext

Biallelic variants in CRIPT cause a Rothmund-Thomson-like syndrome with increased cellular senescence von Averdunk, Luisa, Huetzen, Maxim A., Moreno-Andrés, Daniel, Kalb, Reinhard, McKee, Shane, Hsieh, Tzung-Chien, Seibt, Annette, Schouwink, Marten, Lalani, Seema, Faqeih, Eissa Ali, Brunet, Theresa, Boor, Peter, Neveling, Kornelia, Hoischen, Alexander, Hildebrandt, Barbara, Graf, Elisabeth, Lu, Linchao, Jin, Weidong, Schaper, Joerg, Omer, Jamal A., Demaret, Tanguy, Fleischer, Nicole, Schindler, Detlev, Krawitz, Peter, Mayatepek, Ertan, Wieczorek, Dagmar, Wang, Lisa L., Antonin, Wolfram, Jachimowicz, Ron D., von Felbert, Verena, Distelmaier, Felix

Volltext

Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability von Bogliolo, Massimo, Lyakhovich, Alex, Callén, Elsa, Castellà, Maria, Cappelli, Enrico, Ramírez, María J, Creus, Amadeu, Marcos, Ricard, Kalb, Reinhard, Neveling, Kornelia, Schindler, Detlev, Surrallés, Jordi

Volltext

Hypomorphic Mutations in the Gene Encoding a Key Fanconi Anemia Protein, FANCD2, Sustain a Significant Group of FA-D2 Patients with Severe Phenotype von Kalb, Reinhard, Neveling, Kornelia, Hoehn, Holger, Schneider, Hildegard, Linka, Yvonne, Batish, Sat Dev, Hunt, Curtis, Berwick, Marianne, Callén, Elsa, Surrallés, Jordi, Casado, José A., Bueren, Juan, Dasí, Ángeles, Soulier, Jean, Gluckman, Eliane, Zwaan, C. Michel, van Spaendonk, Rosalina, Pals, Gerard, de Winter, Johan P., Joenje, Hans, Grompe, Markus, Auerbach, Arleen D., Hanenberg, Helmut, Schindler, Detlev

Volltext

A comprehensive strategy for the subtyping of patients with Fanconi anaemia: conclusions from the Spanish Fanconi Anemia Research Network von Antonio Casado, José, Callén, Elsa, Jacome, Ariana, Río, Paula, Castella, Maria, Lobitz, Stephan, Ferro, Teresa, Muñoz, Arturo, Sevilla, Julián, Cantalejo, Ángeles, Cela, Elena, Cervera, José, Sánchez-Calero, Jesús, Badell, Isabel, Estella, Jesús, Dasí, Ángeles, Olivé, Teresa, José Ortega, Juan, Rodriguez-Villa, Antonia, Tapia, María, Molinés, Antonio, Madero, Luis, Segovia, José C, Neveling, Kornelia, Kalb, Reinhard, Schindler, Detlev, Hanenberg, Helmut, Surrallés, Jordi, Bueren, Juan A

Volltext