Small-Molecule Stabilization of Protein-Protein Interactions: An Underestimated Concept in Drug Discovery? von Thiel, Philipp, Kaiser, Markus, Ottmann, Christian

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VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair von van den Boom, Johannes, Wolf, Markus, Weimann, Lena, Schulze, Nina, Li, Fanghua, Kaschani, Farnusch, Riemer, Anne, Zierhut, Christian, Kaiser, Markus, Iliakis, George, Funabiki, Hironori, Meyer, Hemmo

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Protein Quality Control in the Bacterial Periplasm von Merdanovic, Melisa, Clausen, Tim, Kaiser, Markus, Huber, Robert, Ehrmann, Michael

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Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides von Buscaill, Pierre, Chandrasekar, Balakumaran, Sanguankiattichai, Nattapong, Kourelis, Jiorgos, Kaschani, Farnusch, Thomas, Emma L, Morimoto, Kyoko, Kaiser, Markus, Preston, Gail M, Ichinose, Yuki, van der Hoorn, Renier A L

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Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors von Semmler, Alexander, Widmann, Catherine Nichols, Okulla, Thorsten, Urbach, Horst, Kaiser, Markus, Widman, Guido, Mormann, Florian, Weide, Julia, Fliessbach, Klaus, Hoeft, Andreas, Jessen, Frank, Putensen, Christian, Heneka, Michael T

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Determinants of amyloid fibril degradation by the PDZ protease HTRA1 von Poepsel, Simon, Sprengel, Andreas, Sacca, Barbara, Kaschani, Farnusch, Kaiser, Markus, Gatsogiannis, Christos, Raunser, Stefan, Clausen, Tim, Ehrmann, Michael

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Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions von Sijbesma, Eline, Visser, Emira, Plitzko, Kathrin, Thiel, Philipp, Milroy, Lech-Gustav, Kaiser, Markus, Brunsveld, Luc, Ottmann, Christian

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TopBP1 utilises a bipartite GINS binding mode to support genome replication von Day, Matthew, Tetik, Bilal, Parlak, Milena, Almeida-Hernández, Yasser, Räschle, Markus, Kaschani, Farnusch, Siegert, Heike, Marko, Anika, Sanchez-Garcia, Elsa, Kaiser, Markus, Barker, Isabel A., Pearl, Laurence H., Oliver, Antony W., Boos, Dominik

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A homology-guided, genome-based proteome for improved proteomics in the alloploid Nicotiana benthamiana von Kourelis, Jiorgos, Kaschani, Farnusch, Grosse-Holz, Friederike M, Homma, Felix, Kaiser, Markus, van der Hoorn, Renier A L

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Mesenchymal Stem Cell Therapy Protects Lungs from Radiation-Induced Endothelial Cell Loss by Restoring Superoxide Dismutase 1 Expression von Klein, Diana, Steens, Jennifer, Wiesemann, Alina, Schulz, Florian, Kaschani, Farnusch, Röck, Katharina, Yamaguchi, Masahiro, Wirsdörfer, Florian, Kaiser, Markus, Fischer, Jens W, Stuschke, Martin, Jendrossek, Verena

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Fermentative Spirochaetes mediate necromass recycling in anoxic hydrocarbon-contaminated habitats von Dong, Xiyang, Greening, Chris, Brüls, Thomas, Conrad, Ralf, Guo, Kun, Blaskowski, Svenja, Kaschani, Farnusch, Kaiser, Markus, Laban, Nidal Abu, Meckenstock, Rainer U.

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Subtilase SBT5.2 inactivates flagellin immunogenicity in the plant apoplast von Buscaill, Pierre, Sanguankiattichai, Nattapong, Kaschani, Farnusch, Huang, Jie, Mooney, Brian C., Li, Yuge, Lyu, Joy, Sueldo, Daniela, Kaiser, Markus, van der Hoorn, Renier A. L.

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The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase von Blueggel, Mike, Kroening, Alexander, Kracht, Matthias, van den Boom, Johannes, Dabisch, Matthias, Goehring, Anna, Kaschani, Farnusch, Kaiser, Markus, Bayer, Peter, Meyer, Hemmo, Beuck, Christine

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Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana von Grosse‐Holz, Friederike, Madeira, Luisa, Zahid, Muhammad Awais, Songer, Molly, Kourelis, Jiorgos, Fesenko, Mary, Ninck, Sabrina, Kaschani, Farnusch, Kaiser, Markus, Hoorn, Renier A.L.

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Substrate-induced remodeling of the active site regulates human HTRA1 activity von Clausen, Tim, Ehrmann, Michael, Truebestein, Linda, Tennstaedt, Annette, Mönig, Timon, Krojer, Tobias, Canellas, Flavia, Kaiser, Markus

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plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism von Groll, Michael, Schellenberg, Barbara, Bachmann, André S, Archer, Crystal R, Huber, Robert, Powell, Tracy K, Lindow, Steven, Kaiser, Markus, Dudler, Robert

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Activity-based protein profiling as a robust method for enzyme identification and screening in extremophilic Archaea von Zweerink, Susanne, Kallnik, Verena, Ninck, Sabrina, Nickel, Sabrina, Verheyen, Julia, Blum, Marcel, Wagner, Alexander, Feldmann, Ingo, Sickmann, Albert, Albers, Sonja-Verena, Bräsen, Christopher, Kaschani, Farnusch, Siebers, Bettina, Kaiser, Markus

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Persister state-directed transitioning and vulnerability in melanoma von Chauvistré, Heike, Shannan, Batool, Daignault-Mill, Sheena M., Ju, Robert J., Picard, Daniel, Egetemaier, Stefanie, Váraljai, Renáta, Gibhardt, Christine S., Sechi, Antonio, Kaschani, Farnusch, Keminer, Oliver, Stehbens, Samantha J., Liu, Qin, Yin, Xiangfan, Jeyakumar, Kirujan, Vogel, Felix C. E., Krepler, Clemens, Rebecca, Vito W., Kubat, Linda, Lueong, Smiths S., Forster, Jan, Horn, Susanne, Remke, Marc, Ehrmann, Michael, Paschen, Annette, Becker, Jürgen C., Helfrich, Iris, Rauh, Daniel, Kaiser, Markus, Gul, Sheraz, Herlyn, Meenhard, Bogeski, Ivan, Rodríguez-López, José Neptuno, Haass, Nikolas K., Schadendorf, Dirk, Roesch, Alexander

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A chemical inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thaliana von Meesters, Christian, Mönig, Timon, Oeljeklaus, Julian, Krahn, Daniel, Westfall, Corey S, Hause, Bettina, Jez, Joseph M, Kaiser, Markus, Kombrink, Erich

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A novel quenched fluorescent activity-based probe reveals caspase-3 activity in the endoplasmic reticulum during apoptosis von Shaulov-Rotem, Yulia, Merquiol, Emmanuelle, Weiss-Sadan, Tommy, Moshel, Ofra, Salpeter, Seth, Shabat, Doron, Kaschani, Farnusch, Kaiser, Markus, Blum, Galia

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