The Extracellular Matrix Modulates the Metastatic Journey von Kai, FuiBoon, Drain, Allison P., Weaver, Valerie M.

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Force Matters: Biomechanical Regulation of Cell Invasion and Migration in Disease von Kai, FuiBoon, Laklai, Hanane, Weaver, Valerie M

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The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles von Leidal, Andrew M., Huang, Hector H., Marsh, Timothy, Solvik, Tina, Zhang, Dachuan, Ye, Jordan, Kai, FuiBoon, Goldsmith, Juliet, Liu, Jennifer Y., Huang, Yu-Hsin, Monkkonen, Teresa, Vlahakis, Ariadne, Huang, Eric J., Goodarzi, Hani, Yu, Li, Wiita, Arun P., Debnath, Jayanta

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A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression von Woods, Elliot C, Kai, FuiBoon, Barnes, J Matthew, Pedram, Kayvon, Pickup, Michael W, Hollander, Michael J, Weaver, Valerie M, Bertozzi, Carolyn R

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A tension-mediated glycocalyx–integrin feedback loop promotes mesenchymal-like glioblastoma von Barnes, J. Matthew, Kaushik, Shelly, Bainer, Russell O., Sa, Jason K., Woods, Elliot C., Kai, FuiBoon, Przybyla, Laralynne, Lee, Mijeong, Lee, Hye Won, Tung, Jason C., Maller, Ori, Barrett, Alexander S., Lu, Kan V., Lakins, Jonathon N., Hansen, Kirk C., Obernier, Kirsten, Alvarez-Buylla, Arturo, Bergers, Gabriele, Phillips, Joanna J., Nam, Do-Hyun, Bertozzi, Carolyn R., Weaver, Valerie M.

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ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells von Kai, FuiBoon, Ou, Guanqing, Tourdot, Richard W, Stashko, Connor, Gaietta, Guido, Swift, Mark F, Volkmann, Niels, Long, Alexandra F, Han, Yulong, Huang, Hector H, Northey, Jason J, Leidal, Andrew M, Viasnoff, Virgile, Bryant, David M, Guo, Wei, Wiita, Arun P, Guo, Ming, Dumont, Sophie, Hanein, Dorit, Radhakrishnan, Ravi, Weaver, Valerie M

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Deconstructing Mechanotransduction Cues for a Quantitative In Situ Cellular Tomography Workflow von Gaietta, Guido M., Fuiboon, Kai, Weaver, Valerie M., Hanein, Dorit

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Prostate cancer cell migration induced by myopodin isoforms is associated with formation of morphologically and biochemically distinct actin networks von Kai, FuiBoon, Duncan, Roy

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Novel cryo-tomography workflow reveals nanometer-scale responses of epithelial cells to matrix stiffness and dimensionality von Gaietta, Guido, Kai, Fuiboon, Swift, Mark F, Weaver, Valerie M, Volkmann, Niels, Hanein, Dorit

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Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular... von Mekhdjian, Armen H, Kai, FuiBoon, Rubashkin, Matthew G, Prahl, Louis S, Przybyla, Laralynne M, McGregor, Alexandra L, Bell, Emily S, Barnes, J Matthew, DuFort, Christopher C, Ou, Guanqing, Chang, Alice C, Cassereau, Luke, Tan, Steven J, Pickup, Michael W, Lakins, Jonathan N, Ye, Xin, Davidson, Michael W, Lammerding, Jan, Odde, David J, Dunn, Alexander R, Weaver, Valerie M

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Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk von Northey, Jason J., Hayward, Mary-Kate, Yui, Yoshihiro, Stashko, Connor, Kai, FuiBoon, Mouw, Janna K., Thakar, Dhruv, Lakins, Jonathon N., Ironside, Alastair J., Samson, Susan, Mukhtar, Rita A., Hwang, E. Shelley, Weaver, Valerie M.

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Golgi complex-plasma membrane trafficking directed by an autonomous, tribasic Golgi export signal von Parmar, Hirendrasinh B, Barry, Christopher, Kai, Fuiboon, Duncan, Roy

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Abstract 1028: Extracellular matrix dimensionality reduces cellular cortical tension to stimulate pro-survival signaling in mammary epithelial cells von Kai, FuiBoon, Ou, Guanqing, Long, Alexandra, Guo, Wei, Tourdot, Richard, Radhakrishnan, Ravi, Chen, Christopher, Dumont, Sophie, Weaver, Valerie M.

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Abstract 1900: A tension-mediated glycocalyx feedback loop promotes glioblastoma von Kaushik, Shelly, Barnes, James Matthew, Bainer, Russell O., Sa, Jason K., Woods, Elliot C., Kai, Fuiboon, Lakins, Jonathon N., Phillips, Joanna J., Weaver, Valerie M.

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Synaptopodin-2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration von Kai, FuiBoon, Fawcett, James P, Duncan, Roy

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Genetically Encoded Toolbox for Glycocalyx Engineering: Tunable Control of Cell Adhesion, Survival, and Cancer Cell Behaviors von Shurer, Carolyn R, Colville, Marshall J, Gupta, Vivek K, Head, Shelby E, Kai, FuiBoon, Lakins, Jonathon N, Paszek, Matthew J

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Myopodin isoforms alter the chemokinetic response of PC3 cells in response to different migration stimuli via differential effects on Rho-ROCK signaling pathways von KAI, Fuiboon, TANNER, Kaitlyn, KING, Caroline, DUNCAN, Roy

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A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma von Barnes, J. Matthew, Kaushik, Shelly, Bainer, Russell O, Sa, Jason K, Woods, Elliot C, Kai, FuiBoon, Przybyla, Laralynne, Lee, Mijeong, Lee, Hye Won, Tung, Jason C, Maller, Ori, Barrett, Alexander S, Lu, Kan V, Lakins, Jonathon N, Hansen, Kirk C, Obernier, Kirsten, Alvarez-Buylla, Arturo, Bergers, Gabriele, Phillips, Joanna J, Nam, Do-Hyun, Bertozzi, Carolyn R, Weaver, Valerie M

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TMIC-43. A TENSION-MEDIATED GLYCOCALYX FEEDBACK LOOP PROMOTES A MESENCHYMAL, STEM-LIKE PHENOTYPE IN GLIOBLASTOMA von Kaushik, Shelly, Barnes, James Matthew, Bainer, Russell O, Sa, Jason K, Woods, Elliot C, Kai, FuiBoon, Przybyla, Laralynne, Lakins, Jonathon N, Phillips, Joanna J, Nam, Do-Hyun, Bertozzi, Carolyn R, Weaver, Valerie M

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Abstract LB021: Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer progression von Northey, Jason J., Yui, Yoshihiro, Hayward, Mary-Kate, Stashko, Connor, Kai, FuiBoon, Mouw, Janna, Thakar, Dhruv, Lakins, Jonathon, Ironside, Alastair, Samson, Susan, Mukhtar, Rita, Hwang, E. Shelley, Weaver, Valerie

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