A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens von Roberts, Kade D., Zhu, Yan, Azad, Mohammad A. K., Han, Mei-Ling, Wang, Jiping, Wang, Lynn, Yu, Heidi H., Horne, Andrew S., Pinson, Jo-Anne, Rudd, David, Voelcker, Nicolas H., Patil, Nitin A., Zhao, Jinxin, Jiang, Xukai, Lu, Jing, Chen, Ke, Lomovskaya, Olga, Hecker, Scott J., Thompson, Philip E., Nation, Roger L., Dudley, Michael N., Griffith, David C., Velkov, Tony, Li, Jian

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A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity von Deris, Zakuan Z, Akter, Jesmin, Sivanesan, Sivashangarie, Roberts, Kade D, Thompson, Philip E, Nation, Roger L, Li, Jian, Velkov, Tony

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A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening Acinetobacter baumannii von Jiang, Xukai, Patil, Nitin A, Azad, Mohammad A K, Wickremasinghe, Hasini, Yu, Heidi, Zhao, Jinxin, Zhang, Xinru, Li, Mengyao, Gong, Bin, Wan, Lin, Ma, Wendong, Thompson, Philip E, Yang, Kai, Yuan, Bing, Schreiber, Falk, Wang, Lushan, Velkov, Tony, Roberts, Kade D, Li, Jian

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Antimicrobial Activity and Toxicity of the Major Lipopeptide Components of Polymyxin B and Colistin: Last-Line Antibiotics against Multidrug-Resistant Gram-Negative Bacteria von Roberts, Kade D, Azad, Mohammad A. K, Wang, Jiping, Horne, Andrew S, Thompson, Philip E, Nation, Roger L, Velkov, Tony, Li, Jian

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Design and Evaluation of Novel Polymyxin Fluorescent Probes von Yun, Bo, Roberts, Kade D, Thompson, Philip E, Nation, Roger L, Velkov, Tony, Li, Jian

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An Efficient Approach for the Design and Synthesis of Antimicrobial Peptide-Peptide Nucleic Acid Conjugates von Patil, Nitin A, Thombare, Varsha J, Li, Rong, He, Xiaoji, Lu, Jing, Yu, Heidi H, Wickremasinghe, Hasini, Pamulapati, Kavya, Azad, Mohammad A K, Velkov, Tony, Roberts, Kade D, Li, Jian

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Exploring Structure–Activity Relationships and Modes of Action of Laterocidine von Thombare, Varsha J., Swarbrick, James D., Azad, Mohammad A. K., Zhu, Yan, Lu, Jing, Yu, Heidi Y., Wickremasinghe, Hasini, He, Xiaoji, Bandiatmakur, Mahimna, Li, Rong, Bergen, Phillip J., Velkov, Tony, Wang, Jiping, Roberts, Kade D., Li, Jian, Patil, Nitin A.

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Rediscovering the octapeptins von Velkov, Tony, Roberts, Kade D, Li, Jian

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Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells von Li, Mengyao, Azad, Mohammad A K, Thompson, Philip E, Roberts, Kade D, Velkov, Tony, Zhu, Yan, Li, Jian

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Advancing Nitrile‐Aminothiol Strategy for Dual and Sequential Bioconjugation von Thombare, Varsha J., Wu, Yimin, Pamulapati, Kavya, Han, Meiling, Tailhades, Julien, Cryle, Max J., Roberts, Kade D., Velkov, Tony, Li, Jian, Patil, Nitin A.

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Polymyxins: a new hope in combating Gram-negative superbugs? von Velkov, Tony, Roberts, Kade D, Thompson, Philip E, Li, Jian

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Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’ von Velkov, Tony, Roberts, Kade D, Nation, Roger L, Wang, Jiping, Thompson, Philip E, Li, Jian

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Human oligopeptide transporter 2 (PEPT2) mediates cellular uptake of polymyxins von Lu, Xiaoxi, Chan, Ting, Xu, Chenghao, Zhu, Ling, Zhou, Qi Tony, Roberts, Kade D, Chan, Hak-Kim, Li, Jian, Zhou, Fanfan

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An Intelligent Strategy with All-Atom Molecular Dynamics Simulations for the Design of Lipopeptides against Multidrug-Resistant Pseudomonas aeruginosa von Jiang, Xukai, Han, Meiling, Tran, Kevin, Patil, Nitin A., Ma, Wendong, Roberts, Kade D., Xiao, Min, Sommer, Bjorn, Schreiber, Falk, Wang, Lushan, Velkov, Tony, Li, Jian

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Structure–Interaction Relationship of Polymyxins with Lung Surfactant von Jiang, Xukai, Patil, Nitin A., Xu, Yuwen, Wickremasinghe, Hasini, Zhou, Qi Tony, Zhou, Fanfan, Thompson, Philip E., Wang, Lushan, Xiao, Min, Roberts, Kade D., Velkov, Tony, Li, Jian

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Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity von Patil, Nitin A., Ma, Wendong, Jiang, Xukai, He, Xiaoji, Yu, Heidi H., Wickremasinghe, Hasini, Wang, Jiping, Thompson, Philip E., Velkov, Tony, Roberts, Kade D., Li, Jian

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Molecular dynamics simulations informed by membrane lipidomics reveal the structure–interaction relationship of polymyxins with the lipid A-based outer membrane of Acinetobacter ba... von Jiang, Xukai, Yang, Kai, Yuan, Bing, Han, Meiling, Zhu, Yan, Roberts, Kade D, Patil, Nitin A, Li, Jingliang, Gong, Bin, Hancock, Robert E W, Velkov, Tony, Schreiber, Falk, Wang, Lushan, Li, Jian

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Simulations of octapeptin–outer membrane interactions reveal conformational flexibility is linked to antimicrobial potency von Jiang, Xukai, Yang, Kai, Yuan, Bing, Gong, Bin, Wan, Lin, Patil, Nitin A., Swarbrick, James D., Roberts, Kade D., Schreiber, Falk, Wang, Lushan, Velkov, Tony, Li, Jian

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Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria von Velkov, Tony, Gallardo-Godoy, Alejandra, Swarbrick, James D., Blaskovich, Mark. A.T., Elliott, Alysha G., Han, Meiling, Thompson, Philip E., Roberts, Kade D., Huang, Johnny X., Becker, Bernd, Butler, Mark S., Lash, Lawrence H., Henriques, Sónia Troeira, Nation, Roger L., Sivanesan, Sivashangarie, Sani, Marc-Antoine, Separovic, Frances, Mertens, Haydyn, Bulach, Dieter, Seemann, Torsten, Owen, Jeremy, Li, Jian, Cooper, Matthew A.

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Probing the Penetration of Antimicrobial Polymyxin Lipopeptides into Gram-Negative Bacteria von Deris, Zakuan Z, Swarbrick, James D, Roberts, Kade D, Azad, Mohammad A. K, Akter, Jesmin, Horne, Andrew. S, Nation, Roger L, Rogers, Kelly L, Thompson, Phillip E, Velkov, Tony, Li, Jian

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