Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy von Tajan, Mylène, Hennequart, Marc, Cheung, Eric C., Zani, Fabio, Hock, Andreas K., Legrave, Nathalie, Maddocks, Oliver D. K., Ridgway, Rachel A., Athineos, Dimitris, Suárez-Bonnet, Alejandro, Ludwig, Robert L., Novellasdemunt, Laura, Angelis, Nikolaos, Li, Vivian S. W., Vlachogiannis, Georgios, Valeri, Nicola, Mainolfi, Nello, Suri, Vipin, Friedman, Adam, Manfredi, Mark, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.

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Serine is a natural ligand and allosteric activator of pyruvate kinase M2 von Chaneton, Barbara, Hillmann, Petra, Zheng, Liang, Martin, Agnès C. L., Maddocks, Oliver D. K., Chokkathukalam, Achuthanunni, Coyle, Joseph E., Jankevics, Andris, Holding, Finn P., Vousden, Karen H., Frezza, Christian, O’Reilly, Marc, Gottlieb, Eyal

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Metabolic cross-feeding in imbalanced diets allows gut microbes to improve reproduction and alter host behaviour von Henriques, Sílvia F., Dhakan, Darshan B., Serra, Lúcia, Francisco, Ana Patrícia, Carvalho-Santos, Zita, Baltazar, Célia, Elias, Ana Paula, Anjos, Margarida, Zhang, Tong, Maddocks, Oliver D. K., Ribeiro, Carlos

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Metabolic regulation by p53 von Maddocks, Oliver D. K., Vousden, Karen H.

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The KRAS-BCAA-BCAT2 axis in PDAC development von Falcone, Mattia, Maddocks, Oliver D. K.

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Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans von Maddocks, Oliver D K, Short, Abigail J, Donnenberg, Michael S, Bader, Scott, Harrison, David J

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Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models von Kataura, Tetsushi, Sedlackova, Lucia, Sun, Congxin, Kocak, Gamze, Wilson, Niall, Banks, Peter, Hayat, Faisal, Trushin, Sergey, Trushina, Eugenia, Maddocks, Oliver D. K., Oblong, John E., Miwa, Satomi, Imoto, Masaya, Saiki, Shinji, Erskine, Daniel, Migaud, Marie E., Sarkar, Sovan, Korolchuk, Viktor I.

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The creatine–phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis von Papalazarou, Vassilis, Zhang, Tong, Paul, Nikki R., Juin, Amelie, Cantini, Marco, Maddocks, Oliver D. K., Salmeron-Sanchez, Manuel, Machesky, Laura M.

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Phase IIa study of the CD19 antibody MOR208 in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma von Jurczak, W., Zinzani, P.L., Gaidano, G., Goy, A., Provencio, M., Nagy, Z., Robak, T., Maddocks, K., Buske, C., Ambarkhane, S., Winderlich, M., Dirnberger-Hertweck, M., Korolkiewicz, R., Blum, K.A.

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Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity von Carroll, Bernadette, Maetzel, Dorothea, Maddocks, Oliver Dk, Otten, Gisela, Ratcliff, Matthew, Smith, Graham R, Dunlop, Elaine A, Passos, João F, Davies, Owen R, Jaenisch, Rudolf, Tee, Andrew R, Sarkar, Sovan, Korolchuk, Viktor I

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Serine and Functional Metabolites in Cancer von Newman, Alice C, Maddocks, Oliver D.K

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Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells von Marx, Christian, Sonnemann, Jürgen, Beyer, Mandy, Maddocks, Oliver D. K., Lilla, Sergio, Hauzenberger, Irene, Piée‐Staffa, Andrea, Siniuk, Kanstantsin, Nunna, Suneetha, Marx‐Blümel, Lisa, Westermann, Martin, Wagner, Tobias, Meyer, Felix B., Thierbach, René, Mullins, Christina S., Kdimati, Said, Linnebacher, Michael, Neri, Francesco, Heinzel, Thorsten, Wang, Zhao‐Qi, Krämer, Oliver H.

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Incidence and description of autoimmune cytopenias during treatment with ibrutinib for chronic lymphocytic leukemia von Rogers, K A, Ruppert, A S, Bingman, A, Andritsos, L A, Awan, F T, Blum, K A, Flynn, J M, Jaglowski, S M, Lozanski, G, Maddocks, K J, Byrd, J C, Woyach, J A, Jones, J A

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Dinaciclib is a novel cyclin-dependent kinase inhibitor with significant clinical activity in relapsed and refractory chronic lymphocytic leukemia von Flynn, J, Jones, J, Johnson, A J, Andritsos, L, Maddocks, K, Jaglowski, S, Hessler, J, Grever, M R, Im, E, Zhou, H, Zhu, Y, Zhang, D, Small, K, Bannerji, R, Byrd, J C

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Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells von Maddocks, Oliver D. K., Berkers, Celia R., Mason, Susan M., Zheng, Liang, Blyth, Karen, Gottlieb, Eyal, Vousden, Karen H.

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Selinexor suppresses downstream effectors of B-cell activation, proliferation and migration in chronic lymphocytic leukemia cells von Zhong, Y, El-Gamal, D, Dubovsky, J A, Beckwith, K A, Harrington, B K, Williams, K E, Goettl, V M, Jha, S, Mo, X, Jones, J A, Flynn, J M, Maddocks, K J, Andritsos, L A, McCauley, D, Shacham, S, Kauffman, M, Byrd, J C, Lapalombella, R

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p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant von Humpton, Timothy J, Hock, Andreas K, Maddocks, Oliver D K, Vousden, Karen H

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PHD1 regulates p53‐mediated colorectal cancer chemoresistance von Deschoemaeker, Sofie, Di Conza, Giusy, Lilla, Sergio, Martín‐Pérez, Rosa, Mennerich, Daniela, Boon, Lise, Hendrikx, Stefanie, Maddocks, Oliver DK, Marx, Christian, Radhakrishnan, Praveen, Prenen, Hans, Schneider, Martin, Myllyharju, Johanna, Kietzmann, Thomas, Vousden, Karen H, Zanivan, Sara, Mazzone, Massimiliano

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Sensitisation of cancer cells to radiotherapy by serine and glycine starvation von Falcone, Mattia, Uribe, Alejandro Huerta, Papalazarou, Vasileios, Newman, Alice C., Athineos, Dimitris, Stevenson, Katrina, Sauvé, Charles-Etienne Gabriel, Gao, Yajing, Kim, Jin K., Del Latto, Michael, Kierstead, Maria, Wu, Chao, Smith, J. Joshua, Romesser, Paul B., Chalmers, Anthony J., Blyth, Karen, Maddocks, Oliver D. K.

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SERIneALanine Killer: SPT promiscuity inhibits tumour growth via intra-tumoral deoxysphingolipid production von Falcone, Mattia, Maddocks, Oliver D. K.

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