Enhanced microglial activation and proinflammatory cytokine upregulation are linked to increased susceptibility to seizures and neurologic injury in a ‘two-hit’ seizure model von Somera-Molina, Kathleen C, Nair, Sangeetha, Van Eldik, Linda J, Watterson, D. Martin, Wainwright, Mark S

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CO182 Intelligence Quotient (IQ) Scores Among Early-Treated Phenylketonuria (PKU) Patients: Results from a Systematic Literature Review (SLR) von O’Sullivan, F., Tomazos, I., van Spronsen, FJ, Szabo, S.M.., Venkataraman, M., Huria, L., Smith, N., Molony, L., Ingalls, K., Somera-Molina, K.., Harding, C.O..

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P.101 Baseline characteristics/initial safety in RESPOND: phase 4 study of nusinersen in children with SMA who previously received onasemnogene abeparvovec von Proud, C., Parsons, J., Masson, R., Brandsema, J., Finkel, R., Swoboda, K., Finanger, E., Liu, Y., Makepeace, C., Paradis, A., Berger, Z., Wagner, J., Somera-Molina, K.

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P210 Interim results from the RESPOND study evaluating nusinersen in children with spinal muscular atrophy previously treated with onasemnogene abeparvovec von Parsons, J., Kuntz, N., Brandsema, J., Proud, C., Finkel, R., Swoboda, K., Masson, R., Foster, R., Liu, Y., Makepeace, C., Singhi, S., Paradis, A., Berger, Z., Rane, S., Somera-Molina, K.

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SMA - TREATMENT von Proud, C., Parsons, J., Brandsema, J., Finkel, R., Swoboda, K., Foster, R., Makepeace, C., Paradis, A., Berger, Z., Somera-Molina, K.

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SMA - TREATMENT: EP.283 Nusinersen in children with spinal muscular atrophy (SMA) who received onasemnogene abeparvovec: Design of the phase 4, open-label respond study von Proud, C., Parsons, J., Brandsema, J., Finkel, R., Swoboda, K., Foster, R., Makepeace, C., Paradis, A., Berger, Z., Somera-Molina, K.

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P.100 Rationale/design of the phase 3b ASCEND study of investigational higher dose nusinersen in participants with SMA previously treated with risdiplam von Darras, B., Hagenacker, T., Finkel, R., Mercuri, E., Montes, J., Kuntz, N., Farrar, M., Sansone, V., Berger, Z., MacCannell, D., Shen, C., Paradis, A., Bohn, J., Wagner, J., Somera-Molina, K.

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OD18-7. ASCEND : risdiplam治療歴のある脊髄性筋萎縮症患者への高用量nusinersenの投与 von T Homma, NL Kuntz, T Hagenacker, BT Darras, RS Finkel, E Mercuri, J Montes, MA Farrar, VA Sansone, Z Berger, D MacCannell, C Shen, AD Paradis, J Bohn, K Somera-Molina

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