Prediction and modeling of effects on the QTc interval for clinical safety margin assessment, based on single-ascending-dose study data with AZD3839 von Sparve, Erik, Quartino, Angelica L, Lüttgen, Maria, Tunblad, Karin, Gårdlund, Anna Teiling, Fälting, Johanna, Alexander, Robert, Kågström, Jens, Sjödin, Linnea, Bulgak, Alexander, Al-Saffar, Ahmad, Bridgland-Taylor, Matthew, Pollard, Chris, Swedberg, Michael D B, Vik, Torbjörn, Paulsson, Björn

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Assessment of the effects of changes in body temperature on cardiac electrophysiology in anaesthetised guinea pigs von Kågström, Jens, Laumola, Eva-Lena, Poijes, Niklas, Johansson, Maria, Ericson, Ann-Christin

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Evaluation of the guinea pig monophasic action potential (MAP) assay in predicting drug-induced delay of ventricular repolarisation using 12 clinically documented drugs von Kågström, Jens, Sjögren, Eva-Lena, Ericson, Ann-Christin

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Peptidergic control of gastrointestinal blood flow in the estuarine crocodile, Crocodylus porosus von Kagstrom, Jens, Olsson, Catharina, Axelsson, Michael, Franklin, Craig E

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Effects of hNaV1.5 blockers on the rat QRS interval von Ericson, Ann-Christin, Kågström, Jens, Laumola, Eva-Lena, Martinsson, Frida, Eriksson, Anders B.

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Cardiovascular responses to scyliorhinin I and II in the rainbow trout, Oncorhynchus mykiss, in vivo and in vitro von KAGSTRÖM, J, AXELSSON, M, HOLMGREN, S

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EVALUATION OF THE GUINEA PIG MAP ASSAY FOR PREDICTING DRUG-INDUCED QT PROLONGATION USING 11 CLINICALLY DOCUMENTED DRUGS von Kågström, Jens, Ericson, Ann-Christin, Sjögren, Eva-Lena

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Calcitonin Gene-Related Peptide (CGRP), but Not Tachykinins, Causes Relaxation of Small Arteries from the Rainbow Trout Gut von Kågström, Jens, Holmgren, Susanne

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PKPD relationship of hERG blockade and in vivo outcome von Pehrson, Rikard, Al-Saffar, Ahmad, Kagström, Jens, Yan, Hongmei

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VALIDATION OF A GUINEA PIG MODEL OF CARDIAC MONOPHASIC ACTION POTENTIAL AGAINST OTHER PRECLINICAL PREDICTORS OF QT INTERVAL PROLONGATION von Bialecki, Russell A., Duker, Gören, Ollerstam, Anna, Forsström, Elin, Ericson, Ann-Christin, Al-Saffar, Ahmad, Kågström, Jens, Löfberg, Lena, Barthlow, Herbert, Pietras, Mark, Caccese, Robert, Lengel, David, Stevenson, Jennifer, McMahon, Nick, Philp, Karen, Moors, Jackie, Pollard, Chris, Small, Ben, Bridgland-Taylor, Mathew, Valentin, Jean-Pierre

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Temperature induced changes in cardiac electrophysiology in anaesthetised guinea pigs von Kagstrom, Jens, Laumola, Eva-Lena, Poijes, Niklas, Johansson, Maria, Ericson, Ann-Christin

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Peptidergic control of gastrointestinal blood flow in the estuarine crocodile, Crocodylus porosus von Kågström, Jens, Olsson, Catharina, Axelsson, Michael, Franklin, Craig E

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VIP-induced relaxation of small arteries of the rainbow trout, Oncorhynchus mykiss, involves prostaglandin synthesis but not nitric oxide von Kågström, Jens, Holmgren, Susanne

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Peptidergic control of gastrointestinal blood flow in the estuarine crocodile, Crocodylus porosus von KAGSTRÖM, J, OLSSON, C, AXELSSON, M, FRANKLIN, C. E

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