BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 von Tönjes, Martje, Barbus, Sebastian, Park, Yoon Jung, Wang, Wei, Schlotter, Magdalena, Lindroth, Anders M, Pleier, Sabrina V, Bai, Alfa H C, Karra, Daniela, Piro, Rosario M, Felsberg, Jörg, Addington, Adele, Lemke, Dieter, Weibrecht, Irene, Hovestadt, Volker, Rolli, Claudio G, Campos, Benito, Turcan, Sevin, Sturm, Dominik, Witt, Hendrik, Chan, Timothy A, Herold-Mende, Christel, Kemkemer, Ralf, König, Rainer, Schmidt, Kathrin, Hull, William-Edmund, Pfister, Stefan M, Jugold, Manfred, Hutson, Susan M, Plass, Christoph, Okun, Jürgen G, Reifenberger, Guido, Lichter, Peter, Radlwimmer, Bernhard

Volltext

Copy Number Alterations in Enzyme-Coding and Cancer-Causing Genes Reprogram Tumor Metabolism von Sharma, Ashwini Kumar, Eils, Roland, König, Rainer

Volltext

Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models von Palsson, Bernhard Ø, Lewis, Nathan E, Hixson, Kim K, Conrad, Tom M, Lerman, Joshua A, Charusanti, Pep, Polpitiya, Ashoka D, Adkins, Joshua N, Schramm, Gunnar, Purvine, Samuel O, Lopez-Ferrer, Daniel, Weitz, Karl K, Eils, Roland, König, Rainer, Smith, Richard D

Volltext

Temporal progression of gene regulation of peripheral white blood cells explains gender dimorphism of critically ill patients after trauma von Kolte, Amol, König, Rainer

Volltext

Genetic analysis of sudden unexplained death: A multidisciplinary approach von Kauferstein, Silke, Kiehne, Nadine, Jenewein, Tina, Biel, Stephanie, Kopp, Marnie, König, Rainer, Erkapic, Damir, Rothschild, Markus, Neumann, Thomas

Volltext

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations von Reuss, David E., Piro, Rosario M., Jones, David T. W., Simon, Matthias, Ketter, Ralf, Kool, Marcel, Becker, Albert, Sahm, Felix, Pusch, Stefan, Meyer, Jochen, Hagenlocher, Christian, Schweizer, Leonille, Capper, David, Kickingereder, Phillipp, Mucha, Jana, Koelsche, Christian, Jäger, Natalie, Santarius, Thomas, Tarpey, Patrick S., Stephens, Philip J., Andrew Futreal, P., Wellenreuther, Ruth, Kraus, Jürgen, Lenartz, Doris, Herold-Mende, Christel, Hartmann, Christian, Mawrin, Christian, Giese, Nathalia, Eils, Roland, Collins, V. Peter, König, Rainer, Wiestler, Otmar D., Pfister, Stefan M., von Deimling, Andreas

Volltext

Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach von Poos, Alexandra M, Kordaß, Theresa, Kolte, Amol, Ast, Volker, Oswald, Marcus, Rippe, Karsten, König, Rainer

Volltext

MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer von Ward, Aoife, Shukla, Kirti, Balwierz, Aleksandra, Soons, Zita, König, Rainer, Sahin, Özgür, Wiemann, Stefan

Volltext

Cognate Interaction With CD4 + T Cells Instructs Tumor-Associated Macrophages to Acquire M1-Like Phenotype von Eisel, David, Das, Krishna, Dickes, Elke, König, Rainer, Osen, Wolfram, Eichmüller, Stefan B

Volltext

Reprogramming of macrophages employing gene regulatory and metabolic network models von Hoerhold, Franziska, Eisel, David, Oswald, Marcus, Kolte, Amol, Roell, Daniela, Osen, Wolfram, Eichmueller, Stefan B., Koenig, Rainer

Volltext

Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly von Aramillo Irizar, Peer, Schäuble, Sascha, Esser, Daniela, Groth, Marco, Frahm, Christiane, Priebe, Steffen, Baumgart, Mario, Hartmann, Nils, Marthandan, Shiva, Menzel, Uwe, Müller, Jule, Schmidt, Silvio, Ast, Volker, Caliebe, Amke, König, Rainer, Krawczak, Michael, Ristow, Michael, Schuster, Stefan, Cellerino, Alessandro, Diekmann, Stephan, Englert, Christoph, Hemmerich, Peter, Sühnel, Jürgen, Guthke, Reinhard, Witte, Otto W., Platzer, Matthias, Ruppin, Eytan, Kaleta, Christoph

Volltext

Evaluating the effects of automation components in service networks of rail freight von Pollehn, Tobias, Ruf, Moritz, König, Rainer

Volltext

Customized Oligonucleotide Microarray Gene Expression–Based Classification of Neuroblastoma Patients Outperforms Current Clinical Risk Stratification von OBERTHUER, André, BERTHOLD, Frank, SCHWAB, Manfred, BRORS, Benedikt, WESTERMANN, Frank, FISCHER, Matthias, WARNAT, Patrick, HERO, Barbara, KAHLERT, Yvonne, SPITZ, Rudiger, ERNESTUS, Karen, KONIG, Rainer, HAAS, Stefan, EILS, Roland

Volltext

SplicingCompass: differential splicing detection using RNA-seq data von Aschoff, Moritz, Hotz-Wagenblatt, Agnes, Glatting, Karl-Heinz, Fischer, Matthias, Eils, Roland, König, Rainer

Volltext

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein von Schweizer, Leonille, Koelsche, Christian, Sahm, Felix, Piro, Rosario M., Capper, David, Reuss, David E., Pusch, Stefan, Habel, Antje, Meyer, Jochen, Göck, Tanja, Jones, David T. W., Mawrin, Christian, Schittenhelm, Jens, Becker, Albert, Heim, Stephanie, Simon, Matthias, Herold-Mende, Christel, Mechtersheimer, Gunhild, Paulus, Werner, König, Rainer, Wiestler, Otmar D., Pfister, Stefan M., von Deimling, Andreas

Volltext

Estimating the activity of transcription factors by the effect on their target genes von Schacht, Theresa, Oswald, Marcus, Eils, Roland, Eichmüller, Stefan B, König, Rainer

Volltext

Large-scale in silico modeling of metabolic interactions between cell types in the human brain von Palsson, Bernhard Ø, Lewis, Nathan E, Schramm, Gunnar, Bordbar, Aarash, Schellenberger, Jan, Andersen, Michael P, Cheng, Jeffrey K, Patel, Nilam, Yee, Alex, Lewis, Randall A, Eils, Roland, König, Rainer

Volltext

Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas von Westermann, Frank, Muth, Daniel, Benner, Axel, Bauer, Tobias, Henrich, Kai-Oliver, Oberthuer, André, Brors, Benedikt, Beissbarth, Tim, Vandesompele, Jo, Pattyn, Filip, Hero, Barbara, König, Rainer, Fischer, Matthias, Schwab, Manfred

Volltext

A restricted spectrum of NRAS mutations causes Noonan syndrome von Gelb, Bruce D, Gremer, Lothar, Digilio, Cristina, Dentici, Maria L, Roberts, Amy E, Zampino, Giuseppe, Kratz, Christian P, Dallapiccola, Bruno, Mazzanti, Laura, Stuppia, Liborio, Pantaleoni, Francesca, Ahmadian, Mohammad R, Zenker, Martin, Lepri, Francesca, Kutsche, Kerstin, Silengo, Margherita Cirillo, Joshi, Victoria A, König, Rainer, Carta, Claudio, Horn, Denise, Merbitz-Zahradnik, Torsten, Pennacchio, Len A, Mundlos, Stefan, Tartaglia, Marco, Dvorsky, Radovan, Wittinghofer, Alfred, Cirstea, Ion C, Seemanova, Eva, Patton, Michael A, Rossi, Cesare, Kucherlapati, Raju S

Volltext

Global expression analysis of the brown alga Ectocarpus siliculosus (Phaeophyceae) reveals large-scale reprogramming of the transcriptome in response to abiotic stress von Dittami, Simon M, Scornet, Delphine, Petit, Jean-Louis, Ségurens, Béatrice, Da Silva, Corinne, Corre, Erwan, Dondrup, Michael, Glatting, Karl-Heinz, König, Rainer, Sterck, Lieven, Rouzé, Pierre, Van de Peer, Yves, Cock, J Mark, Boyen, Catherine, Tonon, Thierry

Volltext