Multi-omics approaches reveal that diffuse midline gliomas present altered DNA replication and are susceptible to replication stress therapy von Hains, Anastasia E, Chetal, Kashish, Nakatani, Tsunetoshi, Marques, Joana G, Ettinger, Andreas, Junior, Carlos A O Biagi, Gonzalez-Sandoval, Adriana, Pillai, Renjitha, Filbin, Mariella G, Torres-Padilla, Maria-Elena, Sadreyev, Ruslan I, Van Rechem, Capucine

Volltext

TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory von Ausejo-Mauleon, Iker, Labiano, Sara, de la Nava, Daniel, Laspidea, Virginia, Zalacain, Marta, Marrodán, Lucía, García-Moure, Marc, González-Huarriz, Marisol, Hervás-Corpión, Irati, Dhandapani, Laasya, Vicent, Silvestre, Collantes, Maria, Peñuelas, Iván, Becher, Oren J., Filbin, Mariella G., Jiang, Li, Labelle, Jenna, de Biagi-Junior, Carlos A.O., Nazarian, Javad, Laternser, Sandra, Phoenix, Timothy N., van der Lugt, Jasper, Kranendonk, Mariette, Hoogendijk, Raoull, Mueller, Sabine, De Andrea, Carlos, Anderson, Ana C., Guruceaga, Elizabeth, Koschmann, Carl, Yadav, Viveka Nand, Gállego Pérez-Larraya, Jaime, Patiño-García, Ana, Pastor, Fernando, Alonso, Marta M.

Volltext

METB-03. THE DISTINCT GENOMICS OF HIGH-GRADE INFANT GLIOMAS AMONG PEDIATRIC GLIOMAS HARBORING RECEPTOR TYROSINE KINASE FUSIONS von de Biagi-Junior, Carlos A O, Eder, Sebastian K, LaBelle, Jenna, Filbin, Mariella G

Volltext

TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory von Ausejo-Mauleon, Iker, Labiano, Sara, de la Nava, Daniel, Laspidea, Virginia, Zalacain, Marta, Marrodán, Lucía, García-Moure, Marc, González-Huarriz, Marisol, Hervás-Corpión, Irati, Dhandapani, Laasya, Vicent, Silvestre, Collantes, Maria, Peñuelas, Iván, Becher, Oren J, Filbin, Mariella G, Jiang, Li, Labelle, Jenna, de Biagi-Junior, Carlos A O, Nazarian, Javad, Laternser, Sandra, Phoenix, Timothy N, van der Lugt, Jasper, Kranendonk, Mariette, Hoogendijk, Raoull, Mueller, Sabine, De Andrea, Carlos, Anderson, Ana C, Guruceaga, Elizabeth, Koschmann, Carl, Yadav, Viveka Nand

Volltext

EPEN-11. CHARACTERIZATION OF THE SPATIAL ARCHITECTURE OF INTRATUMORAL CELL STATES IN PEDIATRIC HIGH-RISK EPENDYMOMA von Bruckner, Katharina, Madlener, Sibylle, Biagi Junior, Carlos A O, Gabler, Lisa, Senfter, Daniel, Jeong, Daeun, Jiang, Li, Englinger, Bernhard, Jaunecker, Carola, Bilban, Martin, Haberler, Christine, Dorfer, Christian, Rössler, Karl, Kool, Marcel, Berger, Walter, Filbin, Mariella G, Lötsch-Gojo, Daniela, Gojo, Johannes

Volltext

ATRT-10. SINGLE-CELL TRANSCRIPTOME ANALYSIS REVEALS CELLULAR HIERARCHIES AND THERAPEUTIC VULNERABILITIES OF ETMR von Beck, Alexander, Gabler, Lisa, Cruzeiro, Gustavo A V, Lambo, Sander, Englinger, Bernhard, Shaw, McKenzie L, Hack, Olivia A, Liu, Ilon, Junior, Carlos A O de Biagi, Haase, Rebecca D, Klenner, Marbod, Freidel, Pia, Madlener, Sibylle, Mayr, Lisa, Senfter, Daniel, Peyrl, Andreas, Slavc, Irene, Lötsch, Daniela, Dorfer, Christian, Haberler, Christine, Pfister, Stefan M, Baird, Lissa, Chi, Susan N, Alexandrescu, Sanda, Gojo, Johannes, Kool, Marcel, Hovestadt, Volker, Filbin, Mariella G

Volltext

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis von Codo, Ana Campos, Davanzo, Gustavo Gastão, Monteiro, Lauar de Brito, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Virgilio-da-Silva, João Victor, Prodonoff, Juliana Silveira, Carregari, Victor Corasolla, de Biagi Junior, Carlos Alberto Oliveira, Crunfli, Fernanda, Jimenez Restrepo, Jeffersson Leandro, Vendramini, Pedro Henrique, Reis-de-Oliveira, Guilherme, Bispo dos Santos, Karina, Toledo-Teixeira, Daniel A., Parise, Pierina Lorencini, Martini, Matheus Cavalheiro, Marques, Rafael Elias, Carmo, Helison R., Borin, Alexandre, Coimbra, Laís Durço, Boldrini, Vinícius O., Brunetti, Natalia S., Vieira, Andre S., Mansour, Eli, Ulaf, Raisa G., Bernardes, Ana F., Nunes, Thyago A., Ribeiro, Luciana C., Palma, Andre C., Agrela, Marcus V., Moretti, Maria Luiza, Sposito, Andrei C., Pereira, Fabrício Bíscaro, Velloso, Licio Augusto, Vinolo, Marco Aurélio Ramirez, Damasio, André, Proença-Módena, José Luiz, Carvalho, Robson Francisco, Mori, Marcelo A., Martins-de-Souza, Daniel, Nakaya, Helder I., Farias, Alessandro S., Moraes-Vieira, Pedro M.

Volltext

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis von Codo, Ana Campos, Davanzo, Gustavo Gastão, Monteiro, Lauar de Brito, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Virgilio-da-Silva, João Victor, Prodonoff, Juliana Silveira, Carregari, Victor Corasolla, de Biagi Junior, Carlos Alberto Oliveira, Crunfli, Fernanda, Jimenez Restrepo, Jeffersson Leandro, Vendramini, Pedro Henrique, Reis-de-Oliveira, Guilherme, Bispo dos Santos, Karina, Toledo-Teixeira, Daniel A., Parise, Pierina Lorencini, Martini, Matheus Cavalheiro, Marques, Rafael Elias, Carmo, Helison R., Borin, Alexandre, Coimbra, Laís Durço, Boldrini, Vinícius O., Brunetti, Natalia S., Vieira, Andre S., Mansour, Eli, Ulaf, Raisa G., Bernardes, Ana F., Nunes, Thyago A., Ribeiro, Luciana C., Palma, Andre C., Agrela, Marcus V., Moretti, Maria Luiza, Sposito, Andrei C., Pereira, Fabrício Bíscaro, Velloso, Licio Augusto, Vinolo, Marco Aurélio Ramirez, Damasio, André, Proença-Módena, José Luiz, Carvalho, Robson Francisco, Mori, Marcelo A., Martins-de-Souza, Daniel, Nakaya, Helder I., Farias, Alessandro S., Moraes-Vieira, Pedro M.

Volltext

Abstract C51: Targeted inhibition of DUSP1 and DUSP6 suppresses pancreatic adenocarcinoma cells’ growth and glucose metabolism via SAPK/JNK pathway activation von Andrade, Pamela V., Ruckert, Mariana T., Junior, Carlos Alberto O. Biagi, Silveira, Vanessa S.

Volltext