Pan-Src kinase inhibitor treatment attenuates diabetic kidney injury via inhibition of Fyn kinase-mediated endoplasmic reticulum stress von Dorotea, Debra, Jiang, Songling, Pak, Eun Seon, Son, Jung Beom, Choi, Hwan Geun, Ahn, Sung-Min, Ha, Hunjoo

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Enantioselective Total Synthesis of (-)-Clavosolide A and B von Son, Jung-Beom, Kim, Si-Nae, Kim, Na-Yeong, Hwang, Min-Ho, Lee, Won-Sun, Lee, Duck-Hyung

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KF-1607, a Novel Pan Src Kinase Inhibitor, Attenuates Obstruction-Induced Tubulointerstitial Fibrosis in Mice von Dorotea, Debra, Lee, Seungyeon, Lee, Sun Joo, Lee, Gayoung, Son, Jung Beom, Choi, Hwan Geun, Ahn, Sung-Min, Ha, Hunjoo

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Mechanism of action of base-catalyzed oxygenation of phenol derivatives von Lee, Duck-Hyung, Son, Jung Beom, Jung, Seokwon, Song, Jihey, Ham, Seung Wook

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An efficient and enantioselective total synthesis of naturally occurring L-783277 von Choi, Hwan Geun, Son, Jung Beom, Park, Dong-Sik, Ham, Young Jin, Hah, Jung-Mi, Sim, Taebo

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Total Synthesis, Structural Revision, and Absolute Configuration of (+)-Clavosolide A von Son, Jung Beom, Kim, Si Nae, Kim, Na Yeong, Lee, Duck Hyung

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KF-1607, a Novel Pan Src Kinase Inhibitor, Attenuates Obstruction-Induced Tubulointerstitial Fibrosis in Mice von Dorotea, Debra, Lee, Seungyeon, Lee, Sun Joo, Lee, Gayoung, Son, Jung Beom, Choi, Hwan Geun, Ahn, Sung-Min, Ha, Hunjoo

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X‑ray Crystal Structure-Guided Design and Optimization of 7H‑Pyrrolo[2,3‑d]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor von Lee, Younho, Kim, Hyunkyung, Kim, Haelee, Cho, Ha Yeon, Jee, Jun-Goo, Seo, Kyung-Ah, Son, Jung Beom, Ko, Eunhwa, Choi, Hwan Geun, Kim, Nam Doo, Kim, Ikyon

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Abstract LB119: VRN08, a Selective Mps1 Kinase Inhibitor Induces Mitotic Catastrophe and Apoptosis Efficiently in Advanced Cancers Including Rb1-Deficient von Jung, Hong Ryul, Kim, Yeonsil, Kim, Haelee, Kwon, Ji-Hye, Seo, Dong-hyuk, Son, Jung Beom, Kim, Nam Doo, Kim, Daekwon, Kim, Sunghwan

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Abstract P2-13-15: VRN101396, a brain-permeable HER2 inhibitor, shows the anti-tumor activity in preclinical HER2-positive cancer models von Jung, Hong-ryul, Kim, Sunghwan, Yoo, Jihye, Park, Chan mi, Lee, Somi, Lee, Hyoju, Lee, Youngyi, Park, Jinhee, Seo, Kyungah, Seo, Dong-Hyuk, Ko, Eunhwa, Son, Jung Beom, Kim, Deakwon, Choi, Hwan Geun, Kim, Nam Doo

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X-ray Crystal Structure-Guided Design and Optimization of 7 H -Pyrrolo[2,3- d ]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor von Lee, Younho, Kim, Hyunkyung, Kim, Haelee, Cho, Ha Yeon, Jee, Jun-Goo, Seo, Kyung-Ah, Son, Jung Beom, Ko, Eunhwa, Choi, Hwan Geun, Kim, Nam Doo, Kim, Ikyon

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p21‐activated kinase 4 inhibition protects against liver ischemia/reperfusion injury: Role of nuclear factor erythroid 2‐related factor 2 phosphorylation von Mao, Yuancheng, Han, Chang Yeob, Hao, Lihua, Lee, Younho, Son, Jung Beom, Choi, Hwangeun, Lee, Mi Rin, Yang, Jae Do, Hong, Suk Kyun, Suh, Kyung‐Suk, Yu, Hee Chul, Kim, Nam Doo, Bae, Eun Ju, Park, Byung‐Hyun

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Discovery of a potent dual ALK and EGFR T790M inhibitor von Jang, Jaebong, Son, Jung Beom, To, Ciric, Bahcall, Magda, Kim, So Young, Kang, Seock Yong, Mushajiang, Mierzhati, Lee, Younho, Jänne, Pasi A., Choi, Hwan Geun, Gray, Nathanael S.

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Abstract LB139: VRN10, Discovery of Potent Irreversible HER2 Kinase Inhibitors with Intracranial Activity von Kim, Hwan, Lee, Younho, Park, Jinhee, Lee, Youngyi, Choi, Jieun, Yoo, Jihye, Park, Chanmi, Lee, Somi, Ko, Eunhwa, Son, Jung Beom, Choi, Hwan Geun, Kim, Nam Doo, Kim, Daekwon, Kim, Sunghwan

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Abstract 2211: Discovery of orally available and potent MPS1(TTK) kinase inhibitors for anti-cancer drugs von Lee, Younho, Kang, Juhee, Kang, Sein, Kim, Hyunkyung, Seo, Kyung-ah, Choi, Jieun, Ahn, Jaeyoung, Son, Jung Beom, Kim, Nam Doo

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Abstract 2209: Novel therapeutic agents for RET-driven cancers, which is highly potent and selective inhibitor to RET kinase von Li, Hua, Jo, SeoHyun, Do, Woomi, Kim, Hyunkyung, Kim, Hwan, Seo, Kyung-ah, Oh, Ji-hoon, Choi, Jieun, Ahn, Jaeyoung, Son, Jung Beom, Kim, Nam Doo

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Abstract 1466: ORIC-114, a brain penetrant, orally bioavailable, irreversible inhibitor selectively targets EGFR and HER2 exon20 insertion mutants and regresses intracranial NSCLC... von Junttila, Melissa R., Kim, Sunghwan, Lee, Younho, Kim, Hwan, Kang, Juhee, Seok, Jiyoon, Yoo, Jihye, Lee, Youngyi, Seo, Dong-Hyuk, Son, Jung Beom, Kim, Daekwon, Choi, Hwan Geun, Kim, Nam Doo, Das, Akash, Sutimantanapi, Dena, Zavorotinskaya, Tatiana, Chen, Chelsea, Chang, Jae, Panuwat, Matthew, Friedman, Lori

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Abstract P234: ORIC-114, an orally bioavailable, irreversible kinase inhibitor, has superior brain penetrant properties and enhanced potency in preclinical studies of HER2-positive... von Junttila, Melissa R., Long, Jason E., Warne, Robert, Kim, Sunghwan, Lee, Younho, Kim, Hwan, Kang, Juhee, Seok, Jiyoon, Yoo, Jihye, Lee, Youngyi, Seo, Dong-Hyuk Seo, Son, Jung Beom, Kim, Daekwon, Choi, Hwan Geun, Kim, Nam Doo, Zavorotinskaya, Tatiana, Chan, Chelsea, Panuwat, Matthew, Sun, Jessica, Chang, Jae H., Friedman, Lori S.

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Abstract B002: Discovery of selective and potent EGFR kinase inhibitors for exon20 insertion mutations von Kim, Sunghwan, Lee, Younho, Kim, Hwan, Kang, Juhee, Seok, Jiyoon, Seo, Kyung-Ah, Ahn, Jaeyoung, Kang, Hee-Bum, Lee, Sun-Hwa, Son, Jung Beom, Choi, Hwan Geun, Kim, Nam Doo

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p21-activated kinase 4 counteracts PKA-dependent lipolysis by phosphorylating FABP4 and HSL von Yu, Hwang Chan, Jeon, Yong Geun, Na, Ann-Yae, Han, Chang Yeob, Lee, Mi Rin, Yang, Jae Do, Yu, Hee Chul, Son, Jung Beom, Kim, Nam Doo, Kim, Jae Bum, Lee, Sangkyu, Bae, Eun Ju, Park, Byung-Hyun

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