Enhancer polymorphisms at the IKZF1 susceptibility locus for acute lymphoblastic leukemia impact B-cell proliferation and differentiation in both Down syndrome and non-Down syndrom... von Gant, Vincent U., Junco, Jacob J., Terrell, Maci, Rashid, Raushan, Rabin, Karen R.

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A transgenic mouse model of Down syndrome acute lymphoblastic leukemia identifies targetable vulnerabilities von Junco, Jacob J, Rochette, Max, Alozie, Michelle, Rashid, Raushan, Terrell, Maci, Zorman, Barry, Sumazin, Pavel, Rowland, Lauren, Dettorre, Gino, Powell, Reid T, Stephan, Clifford C, Davies, Peter J, Martinez-Moczygemba, Margarita, Yang, Jun J, Rabin, Karen R

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Metabolomic profiling identifies pathways associated with minimal residual disease in childhood acute lymphoblastic leukaemia von Schraw, Jeremy M., Junco, Jacob J., Brown, Austin L., Scheurer, Michael E., Rabin, Karen R., Lupo, Philip J.

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Genomic landscape of Down syndrome–associated acute lymphoblastic leukemia von Li, Zhenhua, Chang, Ti-Cheng, Junco, Jacob J., Devidas, Meenakshi, Li, Yizhen, Yang, Wenjian, Huang, Xin, Hedges, Dale J., Cheng, Zhongshan, Shago, Mary, Carroll, Andrew J., Heerema, Nyla A., Gastier-Foster, Julie, Wood, Brent L., Borowitz, Michael J., Sanclemente, Lauren, Raetz, Elizabeth A., Hunger, Stephen P., Feingold, Eleanor, Rosser, Tracie C., Sherman, Stephanie L., Loh, Mignon L., Mullighan, Charles G., Yu, Jiyang, Wu, Gang, Lupo, Philip J., Rabin, Karen R., Yang, Jun J.

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CRLF2 overexpression results in reduced B-cell differentiation and upregulated E2F signaling in the Dp16 mouse model of Down syndrome von Junco, Jacob J., Zorman, Barry, Gant, Vincent U., Muñoz, Jaime, Lacorazza, H. Daniel, Sumazin, Pavel, Rabin, Karen R.

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Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia von Chen, Taylor J., Du, Wa, Junco, Jacob J., Bridges, Cory Seth, Shen, Ye, Puppi, Monica, Rabin, Karen R., Lacorazza, H. Daniel

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An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance von Junco, Jacob J., Chen, Taylor, Rashid, Raushan, Terrell, Maci, Gant, Vincent U., Miller, Matthew, Rau, Rachel, Lacorazza, H. Daniel, Rabin, Karen R.

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DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells von Zhang, Yinghao, Chang, Fang-Mei, Huang, Jianjun, Junco, Jacob J., Maffi, Shivani K., Pridgen, Hannah I., Catano, Gabriel, Dang, Hong, Ding, Xiang, Yang, Fuquan, Kim, Dae Joon, Slaga, Thomas J., He, Rongqiao, Wei, Sung-Jen

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Role of AMPK and PPARα in the anti‐skin cancer effects of ursolic acid von Junco, Jacob J., Cho, Jiyoon, Mancha, Anna, Malik, Gunjan, Wei, Sung‐Jen, Kim, Dae Joon, Liang, Huiyun, DiGiovanni, John, Slaga, Thomas J.

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Resveratrol and P-glycoprotein inhibitors enhance the anti-skin cancer effects of ursolic acid von Junco, Jacob J, Mancha, Anna, Malik, Gunjan, Wei, Sung-Jen, Kim, Dae Joon, Liang, Huiyun, Slaga, Thomas J

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Ursolic acid and resveratrol synergize with chloroquine to reduce melanoma cell viability von Junco, Jacob J, Mancha-Ramirez, Anna, Malik, Gunjan, Wei, Sung-Jen, Kim, Dae Joon, Liang, Huiyun, Slaga, Thomas J

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Differential effects on lung cancer cell proliferation by agonists of glucocorticoid and PPARα receptors von Liang, Huiyun, Kowalczyk, Piotr, Junco, Jacob J., Klug-De Santiago, Heather L., Malik, Gunjan, Wei, Sung-Jen, Slaga, Thomas J.

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Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice von KOWALCZYK, MAGDALENA C, JUNCO, JACOB J, KOWALCZYK, PIOTR, TOLSTYKH, OLGA, HANAUSEK, MARGARET, SLAGA, THOMAS J, WALASZEK, ZBIGNIEW

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The effects of dissociated glucocorticoids RU24858 and RU24782 on TPA-induced skin tumor promotion biomarkers in SENCAR mice von Kowalczyk, Piotr, Junco, Jacob J., Kowalczyk, Magdalena C., Sosnowska, Renata, Tolstykh, Olga, Walaszek, Zbigniew, Hanausek, Margaret, Slaga, Thomas J.

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Defining the transcriptional control of pediatric AML highlights RARA as a superenhancer-regulated druggable dependency von Perez, Monika W., Sias-Garcia, Oscar, Daramola, Alfred, Wei, Helen, Terrell, Maci, Rashid, Raushan, Park, Woojun D., Duong, Kevin, Horton, Terzah M., Li, Feng, Cherayil, Nikitha, Koren, Jost Vrabic, Gant, Vincent U., Junco, Jacob J., Curry, Choladda V., Stevens, Alexandra M., Lin, Charles Y., Yi, Joanna S.

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The possible separation of 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation and hyperplasia by compound A von Kowalczyk, Piotr, Kowalczyk, Magdalena C., Junco, Jacob J., Tolstykh, Olga, Kinjo, Tatsuya, Truong, Ha, Walaszek, Zbigniew, Hanausek, Margaret, Slaga, Thomas J.

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A Novel Transgenic Mouse Model of Down Syndrome Acute Lymphoblastic Leukemia Identifies Targetable Vulnerabilities von Junco, Jacob J., Rashid, Raushan, Terrell, Maci, Alozie, Michelle, Rochette, Max, Zorman, Barry, Sumazin, Pavel, Rowland, Lauren, Dettorre, Gino, Powell, Reid T., Stephan, Clifford C., Davies, Peter J., Moczygemba, Margie M., Yang, Jun J., Rabin, Karen R.

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Pharmacological Inhibition of MAP2K7 Induces Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia von Chen, Taylor J, Shen, Ye, Bridges, Cory Seth, Park, Chun Shik, Junco, Jacob J., Rabin, Karen R., Lacorazza, H. Daniel

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AnMb1-Cre-driven oncogenicKrasmutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance von Junco, Jacob J., Chen, Taylor, Rashid, Raushan, Terrell, Maci, Gant, Vincent U., Miller, Matthew, Rau, Rachel, Lacorazza, H. Daniel, Rabin, Karen R.

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A Novel Short Latency, High Penetrance Model of KRAS Mutation-Driven T-Cell Acute Lymphoblastic Leukemia von Junco, Jacob J., Gant, Vincent Ulysses, Terrell, Maci S., Miller, Matthew Benjamin, Park, Chun Shik, Chen, Taylor J, Lacorazza, H. Daniel, Goodell, Margaret, Rau, Rachel E., Rabin, Karen R.

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