MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer von Cipponi, Arcadi, Goode, David L., Bedo, Justin, McCabe, Mark J., Pajic, Marina, Croucher, David R., Rajal, Alvaro Gonzalez, Junankar, Simon R., Saunders, Darren N., Lobachevsky, Pavel, Papenfuss, Anthony T., Nessem, Danielle, Nobis, Max, Warren, Sean C., Timpson, Paul, Cowley, Mark, Vargas, Ana C., Qiu, Min R., Generali, Daniele G., Keerthikumar, Shivakumar, Nguyen, Uyen, Corcoran, Niall M., Long, Georgina V., Blay, Jean-Yves, Thomas, David M.

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Epigenomics of mammary gland development von Holliday, Holly, Baker, Laura A, Junankar, Simon R, Clark, Susan J, Swarbrick, Alexander

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Interleukin-27 signaling promotes immunity against endogenously arising murine tumors von Natividad, Karlo D T, Junankar, Simon R, Mohd Redzwan, Norhanani, Nair, Radhika, Wirasinha, Rushika C, King, Cecile, Brink, Robert, Swarbrick, Alexander, Batten, Marcel

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Could the properties of IL-27 make it an ideal adjuvant for anticancer immunotherapy? von Swarbrick, Alexander, Junankar, Simon R, Batten, Marcel

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Analysis of Immune Cell Infiltrates during Squamous Carcinoma Development von Junankar, Simon R., Eichten, Alexandra, Kramer, Annegret, de Visser, Karin E., Coussens, Lisa M.

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Interleukin-27 Signaling Promotes Immunity against Endogenously Arising Murine Tumors. e57469 von Natividad, Karlo DT, Junankar, Simon R, Redzwan, Norhanani Mohd, Nair, Radhika, Wirasinha, Rushika C, King, Cecile, Brink, Robert, Swarbrick, Alexander, Batten, Marcel

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A single-cell and spatially resolved atlas of human breast cancers von Wu, Sunny Z., Al-Eryani, Ghamdan, Roden, Daniel Lee, Junankar, Simon, Harvey, Kate, Andersson, Alma, Thennavan, Aatish, Wang, Chenfei, Torpy, James R., Bartonicek, Nenad, Wang, Taopeng, Larsson, Ludvig, Kaczorowski, Dominik, Weisenfeld, Neil I., Uytingco, Cedric R., Chew, Jennifer G., Bent, Zachary W., Chan, Chia-Ling, Gnanasambandapillai, Vikkitharan, Dutertre, Charles-Antoine, Gluch, Laurence, Hui, Mun N., Beith, Jane, Parker, Andrew, Robbins, Elizabeth, Segara, Davendra, Cooper, Caroline, Mak, Cindy, Chan, Belinda, Warrier, Sanjay, Ginhoux, Florent, Millar, Ewan, Powell, Joseph E., Williams, Stephen R., Liu, X. Shirley, O’Toole, Sandra, Lim, Elgene, Lundeberg, Joakim, Perou, Charles M., Swarbrick, Alexander

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Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer von Wu, Sunny Z, Roden, Daniel L, Wang, Chenfei, Holliday, Holly, Harvey, Kate, Cazet, Aurélie S, Murphy, Kendelle J, Pereira, Brooke, Al‐Eryani, Ghamdan, Bartonicek, Nenad, Hou, Rui, Torpy, James R, Junankar, Simon, Chan, Chia‐Ling, Lam, Chuan En, Hui, Mun N, Gluch, Laurence, Beith, Jane, Parker, Andrew, Robbins, Elizabeth, Segara, Davendra, Mak, Cindy, Cooper, Caroline, Warrier, Sanjay, Forrest, Alistair, Powell, Joseph, O'Toole, Sandra, Cox, Thomas R, Timpson, Paul, Lim, Elgene, Liu, X Shirley, Swarbrick, Alexander

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A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation von Oakes, Samantha R, Gallego-Ortega, David, Stanford, Prudence M, Junankar, Simon, Au, Wendy Wing Yee, Kikhtyak, Zoya, von Korff, Anita, Sergio, Claudio M, Law, Andrew M K, Castillo, Lesley E, Allerdice, Stephanie L, Young, Adelaide I J, Piggin, Catherine, Whittle, Belinda, Bertram, Edward, Naylor, Matthew J, Roden, Daniel L, Donovan, Jesse, Korennykh, Alexei, Goodnow, Christopher C, O'Bryan, Moira K, Ormandy, Christopher J

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Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1 von Junankar, Simon, Lin, Shu, Corey, Eva, Johnen, Heiko, Pankhurst, Greg, Kuffner, Tamara, Tsai, Vicky Wang-Wei, Baldock, Paul A, Herzog, Herbert, Wu, Liyun, Jiang, Lele, Lee, Nicola J, Enriquez, Ronaldo F, Bauskin, Asne R, Lin, En-Ju, Hunter, Mark, Breit, Samuel N, Fairlie, W Douglas, Murakami, MaryAnn M, During, Matthew J, Sainsbury, Amanda, Wang, Chuansong, Brown, David A, Apple, Fred S

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The propeptide mediates formation of stromal Stores of PROMIC-1 : Role in determining prostate cancer outcome von BAUSKIN, Asne R, BROWN, David A, JOHNEN, Heiko, RUSSELL, Pamela J, BARRET, Wade, STRICKER, Phillip D, GRYGIEL, John J, KENCH, James G, HENSHALL, Susan M, SUTHERLAND, Robert L, BREIT, Samuel N, JUNANKAR, Simon, RASIAH, Krishan K, EGGLETON, Sarah, HUNTER, Mark, TAO LIU, SMITH, Dave, KUFFNER, Tamara, PANKHURST, Greg J

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Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB von Holliday, Holly, Roden, Daniel, Junankar, Simon, Wu, Sunny Z., Baker, Laura A., Krisp, Christoph, Chan, Chia-Ling, McFarland, Andrea, Skhinas, Joanna N., Cox, Thomas R., Pal, Bhupinder, Huntington, Nicholas D., Ormandy, Christopher J., Carroll, Jason S., Visvader, Jane, Molloy, Mark P., Swarbrick, Alexander

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Id Proteins Promote a Cancer Stem Cell Phenotype in Mouse Models of Triple Negative Breast Cancer via Negative Regulation of Robo1 von Teo, Wee S, Holliday, Holly, Karthikeyan, Nitheesh, Cazet, Aurélie S, Roden, Daniel L, Harvey, Kate, Konrad, Christina Valbirk, Murali, Reshma, Varghese, Binitha Anu, Thankamony, Archana P, Chan, Chia-Ling, McFarland, Andrea, Junankar, Simon, Ye, Sunny, Yang, Jessica, Nikolic, Iva, Shah, Jaynish S, Baker, Laura A, Millar, Ewan K A, Naylor, Matthew J, Ormandy, Christopher J, Lakhani, Sunil R, Kaplan, Warren, Mellick, Albert S, O'Toole, Sandra A, Swarbrick, Alexander, Nair, Radhika

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ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype von Junankar, Simon, Baker, Laura A., Roden, Daniel L., Nair, Radhika, Elsworth, Ben, Gallego-Ortega, David, Lacaze, Paul, Cazet, Aurélie, Nikolic, Iva, Teo, Wee Siang, Yang, Jessica, McFarland, Andrea, Harvey, Kate, Naylor, Matthew J., Lakhani, Sunil R., Simpson, Peter T., Raghavendra, Ashwini, Saunus, Jodi, Madore, Jason, Kaplan, Warren, Ormandy, Christopher, Millar, Ewan K. A., O’Toole, Sandra, Yun, Kyuson, Swarbrick, Alexander

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Abstract 129: An integrated multi-omic cellular atlas of human breast cancers von Wu, Sunny Z, Al-Eryani, Ghamdan, Roden, Daniel, Junankar, Simon, Harvey, Kate, Andersson, Alma, Thennavan, Aatish, Wang, Chenfei, Torpy, James, Bartonicek, Nenad, Wang, Taopeng, Larsson, Ludvig, Kaczorowski, Dominik, Weisenfeld, Neil I, Uytingco, Cedric R, Chew, Jennifer G, Bent, Zachary W, Chan, Chia-Ling, Gnanasambandapillai, Vikkitharan, Dutertre, Charles-Antoine, Gluch, Laurence, Hui, Mun N, Beith, Jane, Parker, Andrew, Robbins, Elizabeth, Segara, Davendra, Mak, Cindy, Cooper, Caroline, Chan, Belinda, Warrier, Sanjay, Ginhoux, Florent, Millar, Ewan, Powell, Joseph E, Williams, Stephen R, Liu, X. Shirley, O'Toole, Sandra, Lim, Elgene, Lundeberg, Joakim, Perou, Charles M, Swarbrick, Alexander

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Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism von Filipe, Elysse C., Velayuthar, Sipiththa, Philp, Ashleigh, Nobis, Max, Latham, Sharissa L., Parker, Amelia L., Murphy, Kendelle J., Wyllie, Kaitlin, Major, Gretel S., Contreras, Osvaldo, Mok, Ellie T. Y., Enriquez, Ronaldo F., McGowan, Suzanne, Feher, Kristen, Quek, Lake‐Ee, Hancock, Sarah E., Yam, Michelle, Tran, Emmi, Setargew, Yordanos F. I., Skhinas, Joanna N., Chitty, Jessica L., Phimmachanh, Monica, Han, Jeremy Z. R., Cadell, Antonia L., Papanicolaou, Michael, Mahmodi, Hadi, Kiedik, Beata, Junankar, Simon, Ross, Samuel E., Lam, Natasha, Coulson, Rhiannon, Yang, Jessica, Zaratzian, Anaiis, Da Silva, Andrew M., Tayao, Michael, Chin, Ian L., Cazet, Aurélie, Kansara, Maya, Segara, Davendra, Parker, Andrew, Hoy, Andrew J., Harvey, Richard P., Bogdanovic, Ozren, Timpson, Paul, Croucher, David R., Lim, Elgene, Swarbrick, Alexander, Holst, Jeff, Turner, Nigel, Choi, Yu Suk, Kabakova, Irina V., Philp, Andrew, Cox, Thomas R.

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Tumor-induced anorexia and weight loss are mediated by the TGF-[beta] superfamily cytokine MIC-1 von Johnen, Heiko, Lin, Shu, Kuffner, Tamara, Brown, David A, Tsai, Vicky Wang-Wei, Bauskin, Asne R, Wu, Liyun, Pankhurst, Greg, Jiang, Lele, Junankar, Simon, Hunter, Mark, Fairlie, W Douglas, Lee, Nicola J, Enriquez, Ronaldo F, Baldock, Paul A, Corey, Eva, Apple, Fred S, Murakami, MaryAnn M, Lin, En-Ju, Wang, Chuansong, During, Matthew J, Sainsbury, Amanda, Herzog, Herbert, Breit, Samuel N

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Tumor-induced anorexia and weight loss are mediated by the TGF-b superfamily cytokine MIC-1 von Johnen, Heiko, Lin, Shu, Kuffner, Tamara, Brown, David A, Tsai, Vicky Wang-Wei, Bauskin, Asne R, Wu, Liyun, Pankhurst, Greg, Jiang, Lele, Junankar, Simon, Hunter, Mark, Fairlie, W Douglas, Lee, Nicola J, Enriquez, Ronaldo F, Baldock, Paul A, Corey, Eva, Apple, Fred S, Murakami, MaryAnn M, Lin, En-Ju, Wang, Chuansong, During, Matthew J, Sainsbury, Amanda, Herzog, Herbert, Breit, Samuel N

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Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism von Filipe, Elysse C, Velayuthar, Sipiththa, Philp, Ashleigh, Nobis, Max, Latham, Sharissa L, Parker, Amelia L, Murphy, Kendelle J, Wyllie, Kaitlin, Major, Gretel S, Contreras, Osvaldo, Mok, Ellie T.Y, Enriquez, Ronaldo F, Mcgowan, Suzanne, Feher, Kristen, Quek, Lake-Ee, Hancock, Sarah E, Yam, Michelle, Tran, Emmi, Setargew, Yordanos F.I, Skhinas, Joanna N, Chitty, Jessica L, Phimmachanh, Monica, Han, Jeremy Z.R, Cadell, Antonia L, Papanicolaou, Michael, Mahmodi, Hadi, Kiedik, Beata, Junankar, Simon, Ross, Samuel E, Lam, Natasha, Coulson, Rhiannon, Yang, Jessica, Zaratzian, Anaiis, Da Silva, Andrew M, Tayao, Michael, Chin, Ian L, Cazet, Aurelie, Kansara, Maya, Segara, Davendra, Parker, Andrew, Hoy, Andrew J, Harvey, Richard P, Bogdanovic, Ozren, Timpson, Paul, Croucher, David R, Lim, Elgene, Swarbrick, Alexander, Holst, Jeff, Turner, Nigel, Choi, Yu Suk, Kabakova, Irina V, Philp, Andrew, Cox, Thomas R

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Inhibitor of Differentiation 4 (ID4) represses mammary myoepithelial differentiation via inhibition of HEB von Holliday, Holly, Roden, Daniel, Junankar, Simon, Wu, Sunny Z, Baker, Laura A, Krisp, Christoph, Chan, Chia-Ling, McFarland, Andrea, Skhinas, Joanna N, Cox, Thomas R, Pal, Bhupinder, Huntington, Nicholas D, Ormandy, Christopher J, Carroll, Jason S, Visvader, Jane, Molloy, Mark P, Swarbrick, Alexander

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