Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog von Kodan, Atsushi, Yamaguchi, Tomohiro, Nakatsu, Toru, Sakiyama, Keita, Hipolito, Christopher J., Fujioka, Akane, Hirokane, Ryo, Ikeguchi, Keiji, Watanabe, Bunta, Hiratake, Jun, Kimura, Yasuhisa, Suga, Hiroaki, Ueda, Kazumitsu, Kato, Hiroaki

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Structural basis for the spectral difference in luciferase bioluminescence von Hiratake, Jun, Saldanha, Adrian, Sakata, Kanzo, Kobashi, Nobuyuki, Kato, Hiroaki, Nakatsu, Toru, Ichiyama, Susumu

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Involvement of γ-Glutamyl Transpeptidase in Ischemia/Reperfusion-Induced Cardiac Dysfunction in Isolated Rat Hearts von Koyama, Takeshi, Tsubota, Akari, Sawano, Tatsuya, Tawa, Masashi, Watanabe, Bunta, Hiratake, Jun, Nakagawa, Keisuke, Matsumura, Yasuo, Ohkita, Mamoru

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Characterization of raspberry ketone/zingerone synthase, catalyzing the alpha, beta-hydrogenation of phenylbutenones in raspberry fruits von Koeduka, Takao, Watanabe, Bunta, Suzuki, Shiro, Hiratake, Jun, Mano, Jun’ichi, Yazaki, Kazufumi

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Molecular Cloning and Characterization of Bifidobacterium bifidum 1,2-α-l-Fucosidase (AfcA), a Novel Inverting Glycosidase (Glycoside Hydrolase Family 95) von KATAYAMA, Takane, SAKUMA, Akiko, KIMURA, Takatoshi, MAKIMURA, Yutaka, HIRATAKE, Jun, SAKATA, Kanzo, YAMANOI, Takashi, KUMAGAI, Hidehiko, YAMAMOTO, Kenji

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Enhancement of production of eugenol and its glycosides in transgenic aspen plants via genetic engineering von Koeduka, Takao, Suzuki, Shiro, Iijima, Yoko, Ohnishi, Toshiyuki, Suzuki, Hideyuki, Watanabe, Bunta, Shibata, Daisuke, Umezawa, Toshiaki, Pichersky, Eran, Hiratake, Jun

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A sulfoximine-based inhibitor of human asparagine synthetase kills l-asparaginase-resistant leukemia cells von Ikeuchi, Hideyuki, Ahn, Yong-Mo, Otokawa, Takuya, Watanabe, Bunta, Hegazy, Lamees, Hiratake, Jun, Richards, Nigel G.J.

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Enzyme inhibitors as chemical tools to study enzyme catalysis: rational design, synthesis, and applications von Hiratake, Jun

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Engineering of Pseudomonas aeruginosa lipase by directed evolution for enhanced amidase activity: mechanistic implication for amide hydrolysis by serine hydrolases von Nakagawa, Yuichi, Hasegawa, Atsuko, Hiratake, Jun, Sakata, Kanzo

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Cystathionine Is a Novel Substrate of Cystine/Glutamate Transporter von Kobayashi, Sho, Sato, Mami, Kasakoshi, Takayuki, Tsutsui, Takumi, Sugimoto, Masahiro, Osaki, Mitsuhiko, Okada, Futoshi, Igarashi, Kiharu, Hiratake, Jun, Homma, Takujiro, Conrad, Marcus, Fujii, Junichi, Soga, Tomoyoshi, Bannai, Shiro, Sato, Hideyo

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Crystal Structure of γ-Glutamylcysteine Synthetase: Insights into the Mechanism of Catalysis by a Key Enzyme for Glutathione Homeostasis von Hibi, Takao, Nii, Hiroshi, Nakatsu, Toru, Kimura, Akira, Kato, Hiroaki, Hiratake, Jun, Oda, Jun'ichi, Petsko, Gregory A.

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Molecular Design of Spacer-N-Linked Sialoglycopolypeptide as Polymeric Inhibitors Against Influenza Virus Infection von Ogata, Makoto, Hidari, Kazuya I. P. J, Kozaki, Wataru, Murata, Takeomi, Hiratake, Jun, Park, Enoch Y, Suzuki, Takashi, Usui, Taichi

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Aminophosphonic and Aminoboronic Acids as Key Elements of a Transition State Analogue Inhibitor of Enzymes von Hiratake, Jun, Oda, Jun'ichi

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Sensitive β-galactosidase-targeting fluorescence probe for visualizing small peritoneal metastatic tumours in vivo von Asanuma, Daisuke, Sakabe, Masayo, Kamiya, Mako, Yamamoto, Kyoko, Hiratake, Jun, Ogawa, Mikako, Kosaka, Nobuyuki, Choyke, Peter L., Nagano, Tetsuo, Kobayashi, Hisataka, Urano, Yasuteru

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A critical electrostatic interaction mediates inhibitor recognition by human asparagine synthetase von Ikeuchi, Hideyuki, Meyer, Megan E., Ding, Yun, Hiratake, Jun, Richards, Nigel G.J.

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A detailed biochemical characterization of phosphopantothenate synthetase, a novel enzyme involved in coenzyme A biosynthesis in the Archaea von Ishibashi, Takuya, Tomita, Hiroya, Yokooji, Yuusuke, Morikita, Tatsuya, Watanabe, Bunta, Hiratake, Jun, Kishimoto, Asako, Kita, Akiko, Miki, Kunio, Imanaka, Tadayuki, Atomi, Haruyuki

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Involvement of γ-Glutamyl Transpeptidase in Ischemia/Reperfusion-Induced Cardiac Dysfunction in Isolated Rat Hearts von Takeshi Koyamaa, Akari Tsubotaa, Tatsuya Sawanoa, b, Masashi Tawaa, c, Bunta Watanabed, Jun Hirataked, Keisuke Nakagawaa, Yasuo Matsumuraa, Mamoru Ohkitaa

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Synthesis and evaluation of the inhibitory activity of the four stereoisomers of the potent and selective human γ-glutamyl transpeptidase inhibitor GGsTop von Watanabe, Bunta, Tabuchi, Yukiko, Wada, Kei, Hiratake, Jun

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Cystathionine is a novel substrate of cystine/glutamate transporter: implications for immune function von Kobayashi, Sho, Sato, Mami, Kasakoshi, Takayuki, Tsutsui, Takumi, Sugimoto, Masahiro, Osaki, Mitsuhiko, Okada, Futoshi, Igarashi, Kiharu, Hiratake, Jun, Homma, Takujiro, Conrad, Marcus, Fujii, Junichi, Soga, Tomoyoshi, Bannai, Shiro, Sato, Hideyo

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An improved synthesis of the potent and selective γ-glutamyl transpeptidase inhibitor GGsTop together with an inhibitory activity evaluation of its potential hydrolysis products von Watanabe, Bunta, Morikita, Tatsuya, Tabuchi, Yukiko, Kobayashi, Ryoto, Li, Chunjie, Yamamoto, Masakazu, Koeduka, Takao, Hiratake, Jun

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