An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED von Qi, Wei, Zhao, Kehao, Gu, Justin, Huang, Ying, Wang, Youzhen, Zhang, Hailong, Zhang, Man, Zhang, Jeff, Yu, Zhengtian, Li, Ling, Teng, Lin, Chuai, Shannon, Zhang, Chao, Zhao, Mengxi, Chan, HoMan, Chen, Zijun, Fang, Douglas, Fei, Qi, Feng, Leying, Feng, Lijian, Gao, Yuan, Ge, Hui, Ge, Xinjian, Li, Guobin, Lingel, Andreas, Lin, Ying, Liu, Yueqin, Luo, Fangjun, Shi, Minlong, Wang, Long, Wang, Zhaofu, Yu, Yanyan, Zeng, Jue, Zeng, Chenhui, Zhang, Lijun, Zhang, Qiong, Zhou, Shaolian, Oyang, Counde, Atadja, Peter, Li, En

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Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation von Qi, Wei, Chan, HoMan, Tenga, Lin, Li, Ling, Chuai, Shannon, Zhang, Ruipeng, Zeng, Jue, Li, Min, Fan, Hong, Lin, Ying, Gu, Justin, Ardayfio, Ophelia, Zhang, Ji-Hu, Yan, Xiaoxia, Fang, Jialuo, Mi, Yuan, Zhang, Man, Zhou, Tao, Feng, Grace, Chen, Zijun, Li, Guobin, Yang, Teddy, Zhao, Kehao, Liu, Xianghui, Yu, Zhengtian, Lu, Chris X., Atadja, Peter, Li, En

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Multi-century flow reconstruction of the Lhasa River, China von Zeng, Jue, Yu, Bofu, Fu, Xudong, Hu, Hongchang

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Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53 von Wang, Ting, Zeng, Jue, Lowe, Craig B, Sellers, Robert G, Salama, Sofie R, Yang, Min, Burgess, Shawn M, Brachmann, Rainer K, Haussler, David

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Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase von Lingel, Andreas, Sendzik, Martin, Huang, Ying, Shultz, Michael D, Cantwell, John, Dillon, Michael P, Fu, Xingnian, Fuller, John, Gabriel, Tobias, Gu, Justin, Jiang, Xiangqing, Li, Ling, Liang, Fang, McKenna, Maureen, Qi, Wei, Rao, Weijun, Sheng, Xijun, Shu, Wei, Sutton, James, Taft, Benjamin, Wang, Long, Zeng, Jue, Zhang, Hailong, Zhang, Maya, Zhao, Kehao, Lindvall, Mika, Bussiere, Dirksen E

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A Framework for Land Use Scenes Classification Based on Landscape Photos von Xu, Shiwu, Zhang, Shihui, Zeng, Jue, Li, Tingyu, Guo, Qinghua, Jin, Shichao

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Split luciferase-based biosensors for characterizing EED binders von Li, Ling, Feng, Lijian, Shi, Minlong, Zeng, Jue, Chen, Zijun, Zhong, Li, Huang, Li, Guo, Weihui, Huang, Ying, Qi, Wei, Lu, Chris, Li, En, Zhao, Kehao, Gu, Justin

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Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers von Dearth, Lawrence R., Qian, Hua, Wang, Ting, Baroni, Timothy E., Zeng, Jue, Chen, Stephanie W., Yi, Sun Young, Brachmann, Rainer K.

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Choosing where to look next in a mutation sequence space: Active Learning of informative p53 cancer rescue mutants von Danziger, Samuel A., Zeng, Jue, Wang, Ying, Brachmann, Rainer K., Lathrop, Richard H.

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Functional census of mutation sequence spaces: the example of p53 cancer rescue mutants von Danziger, S.A., Swamidass, S.J., Jue Zeng, Dearth, L.R., Qiang Lu, Chen, J.H., Cheng, J., Hoang, V.P., Saigo, H., Luo, R., Baldi, P., Brachmann, R.K., Lathrop, R.H.

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MAGED2 : A novel p53-dissociator von PAPAGEORGIO, Chris, BRACHMANN, Rainer, JUE ZENG, CULVERHOUSE, Robert, WANGHAI ZHANG, MCLEOD, Howard

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A Global Suppressor Motif for p53 Cancer Mutants von Baroni, Timothy E., Wang, Ting, Qian, Hua, Dearth, Lawrence R., Truong, Lan N., Zeng, Jue, Denes, Alec E., Chen, Stephanie W., Brachmann, Rainer K., Korsmeyer, Stanley J.

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Study on superplastic behaviour of cold rolled Inconel 718 alloy with δ phase dispersion distribution von Zeng, Jue, Huang, Yuqi, Yang, Xu, Wang, Bingxing, Wang, Bin

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SPINK2 is a prognostic biomarker related to immune infiltration in acute myeloid leukemia von Chen, Xiaohe, Zhao, Lifen, Yu, Tian, Zeng, Jue, Chen, Ming

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miR‑1271‑5p inhibits cell proliferation and induces apoptosis in acute myeloid leukemia by targeting ZIC2 von Chen, Xiaohe, Yang, Shouhang, Zeng, Jue, Chen, Ming

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Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy von Huang, Ying, Zhang, Jeff, Yu, Zhengtian, Zhang, Hailong, Wang, Youzhen, Lingel, Andreas, Qi, Wei, Gu, Justin, Zhao, Kehao, Shultz, Michael D, Wang, Long, Fu, Xingnian, Sun, Yongfeng, Zhang, Qiong, Jiang, Xiangqing, Zhang, Jiangwei, Zhang, Chunye, Li, Ling, Zeng, Jue, Feng, Lijian, Zhang, Chao, Liu, Yueqin, Zhang, Man, Zhang, Lijun, Zhao, Mengxi, Gao, Zhenting, Liu, Xianghui, Fang, Douglas, Guo, Haibing, Mi, Yuan, Gabriel, Tobias, Dillon, Michael P, Atadja, Peter, Oyang, Counde

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Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies von Huang, Ying, Sendzik, Martin, Zhang, Jeff, Gao, Zhenting, Sun, Yongfeng, Wang, Long, Gu, Justin, Zhao, Kehao, Yu, Zhengtian, Zhang, Lijun, Zhang, Qiong, Blanz, Joachim, Chen, Zijun, Dubost, Valérie, Fang, Douglas, Feng, Lijian, Fu, Xingnian, Kiffe, Michael, Li, Ling, Luo, Fangjun, Luo, Xiao, Mi, Yuan, Mistry, Prakash, Pearson, David, Piaia, Alessandro, Scheufler, Clemens, Terranova, Remi, Weiss, Andreas, Zeng, Jue, Zhang, Hailong, Zhang, Jiangwei, Zhao, Mengxi, Dillon, Michael P, Jeay, Sebastien, Qi, Wei, Moggs, Jonathan, Pissot-Soldermann, Carole, Li, En, Atadja, Peter, Lingel, Andreas, Oyang, Counde

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Research on Network Equilibrium Model of Online Shopping Supply Chain System in Promotion Based on Customer Behavior von Zhou, Ye, Zeng, Jue, Zhang, Mengxiao, He, Hui

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Abstract LB-288: An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED von Qi, Wei, Zhao, Kehao, Gu, Justin, Huang, Ying, Wang, Youzhen, Zhang, Hailong, Zhang, Man, Zhang, Jeff, Yu, Zhengtian, Li, Ling, Teng, Lin, Chuai, Shannon, Zhang, Chao, Zhao, Mengxi, Chan, HoMan, Chen, Zijun, Fang, Douglas, Qi, Fei, Feng, Leying, Feng, Lijian, Gao, Yuan, Ge, Hui, Ge, Xinjian, Lingel, Andreas, Li, Guobin, Lin, Ying, Liu, Yueqin, Luo, Fangjun, Shi, Minlong, Wang, Long, Wang, Zhaofu, Yu, Yanyan, Zeng, Jue, Zeng, Chenhui, Zhang, Lijun, Zhang, Qiong, Zhou, Shaolian, Oyang, Counde, Atadja, Peter, Li, En

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Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase von Lingel, Andreas, Sendzik, Martin, Huang, Ying, Shultz, Michael D., Cantwell, John, Dillon, Michael P., Fu, Xingnian, Fuller, John, Gabriel, Tobias, Gu, Justin, Jiang, Xiangqing, Li, Ling, Liang, Fang, McKenna, Maureen, Qi, Wei, Rao, Weijun, Sheng, Xijun, Shu, Wei, Sutton, James, Taft, Benjamin, Wang, Long, Zeng, Jue, Zhang, Hailong, Zhang, Maya, Zhao, Kehao, Lindvall, Mika, Bussiere, Dirksen E.

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