CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells von Kurt, Ibrahim C., Zhou, Ronghao, Iyer, Sowmya, Garcia, Sara P., Miller, Bret R., Langner, Lukas M., Grünewald, Julian, Joung, J. Keith

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Gene therapy comes of age von Dunbar, Cynthia E, High, Katherine A, Joung, J Keith, Kohn, Donald B, Ozawa, Keiya, Sadelain, Michel

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PrimeDesign software for rapid and simplified design of prime editing guide RNAs von Hsu, Jonathan Y., Grünewald, Julian, Szalay, Regan, Shih, Justine, Anzalone, Andrew V., Lam, Kin Chung, Shen, Max W., Petri, Karl, Liu, David R., Joung, J. Keith, Pinello, Luca

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Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells von Kleinstiver, Benjamin P, Tsai, Shengdar Q, Prew, Michelle S, Nguyen, Nhu T, Welch, Moira M, Lopez, Jose M, McCaw, Zachary R, Aryee, Martin J, Joung, J Keith

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CRISPResso2 provides accurate and rapid genome editing sequence analysis von Clement, Kendell, Rees, Holly, Canver, Matthew C., Gehrke, Jason M., Farouni, Rick, Hsu, Jonathan Y., Cole, Mitchel A., Liu, David R., Joung, J. Keith, Bauer, Daniel E., Pinello, Luca

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Therapeutic base editing of human hematopoietic stem cells von Zeng, Jing, Wu, Yuxuan, Ren, Chunyan, Bonanno, Jasmine, Shen, Anne H., Shea, Devlin, Gehrke, Jason M., Clement, Kendell, Luk, Kevin, Yao, Qiuming, Kim, Rachel, Wolfe, Scot A., Manis, John P., Pinello, Luca, Joung, J. Keith, Bauer, Daniel E.

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs von Fu, Yanfang, Sander, Jeffry D, Reyon, Deepak, Cascio, Vincent M, Joung, J Keith

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Zinc-finger Nucleases: The Next Generation Emerges von Cathomen, Toni, Keith Joung, J

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Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors von Grünewald, Julian, Zhou, Ronghao, Garcia, Sara P., Iyer, Sowmya, Lareau, Caleb A., Aryee, Martin J., Joung, J. Keith

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Discovery of widespread type I and type V CRISPR-Cas inhibitors von Marino, Nicole D, Zhang, Jenny Y, Borges, Adair L, Sousa, Alexander A, Leon, Lina M, Rauch, Benjamin J, Walton, Russell T, Berry, Joel D, Joung, J Keith, Kleinstiver, Benjamin P, Bondy-Denomy, Joseph

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Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing von Tsai, Shengdar Q, Wyvekens, Nicolas, Khayter, Cyd, Foden, Jennifer A, Thapar, Vishal, Reyon, Deepak, Goodwin, Mathew J, Aryee, Martin J, Joung, J Keith

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells von Fu, Yanfang, Foden, Jennifer A, Khayter, Cyd, Maeder, Morgan L, Reyon, Deepak, Joung, J Keith, Sander, Jeffry D

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Adopt a moratorium on heritable genome editing von Lander, Eric S., Baylis, Françoise, Zhang, Feng, Charpentier, Emmanuelle, Berg, Paul, Bourgain, Catherine, Friedrich, Bärbel, Joung, J. Keith, Li, Jinsong, Liu, David, Naldini, Luigi, Nie, Jing-Bao, Qiu, Renzong, Schoene-Seifert, Bettina, Shao, Feng, Terry, Sharon, Wei, Wensheng, Winnacker, Ernst-Ludwig

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Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing von Kleinstiver, Benjamin P., Sousa, Alexander A., Walton, Russell T., Tak, Y. Esther, Hsu, Jonathan Y., Clement, Kendell, Welch, Moira M., Horng, Joy E., Malagon-Lopez, Jose, Scarfò, Irene, Maus, Marcela V., Pinello, Luca, Aryee, Martin J., Joung, J. Keith

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Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition von Kleinstiver, Benjamin P, Prew, Michelle S, Tsai, Shengdar Q, Nguyen, Nhu T, Topkar, Ved V, Zheng, Zongli, Joung, J Keith

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Enhanced proofreading governs CRISPR–Cas9 targeting accuracy von Chen, Janice S., Dagdas, Yavuz S., Kleinstiver, Benjamin P., Welch, Moira M., Sousa, Alexander A., Harrington, Lucas B., Sternberg, Samuel H., Joung, J. Keith, Yildiz, Ahmet, Doudna, Jennifer A.

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Heritable and precise zebrafish genome editing using a CRISPR-Cas system von Hwang, Woong Y, Fu, Yanfang, Reyon, Deepak, Maeder, Morgan L, Kaini, Prakriti, Sander, Jeffry D, Joung, J Keith, Peterson, Randall T, Yeh, Jing-Ruey Joanna

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CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells von Petri, Karl, Zhang, Weiting, Ma, Junyan, Schmidts, Andrea, Lee, Hyunho, Horng, Joy E., Kim, Daniel Y., Kurt, Ibrahim C., Clement, Kendell, Hsu, Jonathan Y., Pinello, Luca, Maus, Marcela V., Joung, J. Keith, Yeh, Jing-Ruey Joanna

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Optimization of AsCas12a for combinatorial genetic screens in human cells von DeWeirdt, Peter C., Sanson, Kendall R., Sangree, Annabel K., Hegde, Mudra, Hanna, Ruth E., Feeley, Marissa N., Griffith, Audrey L., Teng, Teng, Borys, Samantha M., Strand, Christine, Joung, J. Keith, Kleinstiver, Benjamin P., Pan, Xuewen, Huang, Alan, Doench, John G.

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GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases von Tsai, Shengdar Q, Zheng, Zongli, Nguyen, Nhu T, Liebers, Matthew, Topkar, Ved V, Thapar, Vishal, Wyvekens, Nicolas, Khayter, Cyd, Iafrate, A John, Le, Long P, Aryee, Martin J, Joung, J Keith

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