DX‐8951F, a water‐soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN‐38‐resistant variant von Joto, Noriko, Ishii, Mineko, Minami, Megumi, Kuga, Hiroshi, Mitsui, Ikuo, Tohgo, Akiko

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Antitumor Effect of DT-5461, a Lipid a Derivative, Against Human Tumor Xenografts Is Mediated by Intratumoral Production of Tumor Necrosis Factor and Affected by Host Immunosuppres... von Kumazawa, Eiji, Jimbo, Takeshi, Akimoto, Toshihiko, Joto, Noriko, Tohgo, Akiko

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Production of tumor necrosis factor induced by synthetic low-toxicity lipid a analog, DT-5461a, is mediated by LPS receptor sites and tyrosine kinase—MAP kinase signaling pathway i... von Joto, Noriko, Akimoto, Toshihiko, Someya, Kazuhiko, Tohgo, Akiko

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Intratumoral production of tumor necrosis factor augmented by endogenous interferons results in potent antitumor effects of DT-5461, a synthetic lipid A analog von KUMAZAWA, E, AKIMOTO, T, KITA, Y, JIMBO, T, JOTO, N, TOHGO, A

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Antitumor effect of DT-5461a, a synthetic low-toxicity lipid a analog, involves endogenous tumor necrosis factor induction subsequent to macrophage activation von Akimoto, Toshihiko, Kumazawa, Eiji, Jimbo, Takeshi, Joto, Noriko, Tohgo, Akiko

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