Cells of the adult human heart von Litviňuková, Monika, Talavera-López, Carlos, Maatz, Henrike, Reichart, Daniel, Worth, Catherine L., Lindberg, Eric L., Kanda, Masatoshi, Polanski, Krzysztof, Heinig, Matthias, Lee, Michael, Nadelmann, Emily R., Roberts, Kenny, Tuck, Liz, Fasouli, Eirini S., DeLaughter, Daniel M., McDonough, Barbara, Wakimoto, Hiroko, Gorham, Joshua M., Samari, Sara, Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Patone, Giannino, Boyle, Joseph J., Zhang, Hongbo, Zhang, Hao, Viveiros, Anissa, Oudit, Gavin Y., Bayraktar, Omer Ali, Seidman, J. G., Seidman, Christine E., Noseda, Michela, Hubner, Norbert, Teichmann, Sarah A.

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A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice von Green, Eric M., Wakimoto, Hiroko, Anderson, Robert L., Evanchik, Marc J., Gorham, Joshua M., Harrison, Brooke C., Henze, Marcus, Kawas, Raja, Oslob, Johan D., Rodriguez, Hector M., Song, Yonghong, Wan, William, Leinwand, Leslie A., Spudich, James A., McDowell, Robert S., Seidman, J. G., Seidman, Christine E.

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Single-Cell Resolution of Temporal Gene Expression during Heart Development von DeLaughter, Daniel M., Bick, Alexander G., Wakimoto, Hiroko, McKean, David, Gorham, Joshua M., Kathiriya, Irfan S., Hinson, John T., Homsy, Jason, Gray, Jesse, Pu, William, Bruneau, Benoit G., Seidman, J.G., Seidman, Christine E.

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Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers von Anderson, Robert L., Trivedi, Darshan V., Sarkar, Saswata S., Henze, Marcus, Ma, Weikang, Gong, Henry, Rogers, Christopher S., Gorham, Joshua M., Wong, Fiona L., Morck, Makenna M., Seidman, Jonathan G., Ruppel, Kathleen M., Irving, Thomas C., Cooke, Roger, Green, Eric M., Spudich, James A.

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Fulminant Myocarditis with Combination Immune Checkpoint Blockade von Johnson, Douglas B, Balko, Justin M, Compton, Margaret L, Chalkias, Spyridon, Gorham, Joshua, Xu, Yaomin, Hicks, Mellissa, Puzanov, Igor, Alexander, Matthew R, Bloomer, Tyler L, Becker, Jason R, Slosky, David A, Phillips, Elizabeth J, Pilkinton, Mark A, Craig-Owens, Laura, Kola, Nina, Plautz, Gregory, Reshef, Daniel S, Deutsch, Jonathan S, Deering, Raquel P, Olenchock, Benjamin A, Lichtman, Andrew H, Roden, Dan M, Seidman, Christine E, Koralnik, Igor J, Seidman, Jonathan G, Hoffman, Robert D, Taube, Janis M, Diaz, Luis A, Anders, Robert A, Sosman, Jeffrey A, Moslehi, Javid J

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Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice von Reichart, Daniel, Newby, Gregory A., Wakimoto, Hiroko, Lun, Mingyue, Gorham, Joshua M., Curran, Justin J., Raguram, Aditya, DeLaughter, Daniel M., Conner, David A., Marsiglia, Júlia D. C., Kohli, Sajeev, Chmatal, Lukas, Page, David C., Zabaleta, Nerea, Vandenberghe, Luk, Liu, David R., Seidman, Jonathan G., Seidman, Christine

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Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy von Hinson, John T., Chopra, Anant, Nafissi, Navid, Polacheck, William J., Benson, Craig C., Swist, Sandra, Gorham, Joshua, Yang, Luhan, Schafer, Sebastian, Sheng, Calvin C., Haghighi, Alireza, Homsy, Jason, Hubner, Norbert, Church, George, Cook, Stuart A., Linke, Wolfgang A., Chen, Christopher S., Seidman, J. G., Seidman, Christine E.

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Myc targeted CDK18 promotes ATR and homologous recombination to mediate PARP inhibitor resistance in glioblastoma von Ning, Jian-Fang, Stanciu, Monica, Humphrey, Melissa R., Gorham, Joshua, Wakimoto, Hiroko, Nishihara, Reiko, Lees, Jacqueline, Zou, Lee, Martuza, Robert L., Wakimoto, Hiroaki, Rabkin, Samuel D.

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ViroFind: A novel target-enrichment deep-sequencing platform reveals a complex JC virus population in the brain of PML patients von Chalkias, Spyros, Gorham, Joshua M, Mazaika, Erica, Parfenov, Michael, Dang, Xin, DePalma, Steve, McKean, David, Seidman, Christine E, Seidman, Jonathan G, Koralnik, Igor J

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Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter von Bick, Alexander G., Wakimoto, Hiroko, Kamer, Kimberli J., Sancak, Yasemin, Goldberger, Olga, Axelsson, Anna, DeLaughter, Daniel M., Gorham, Joshua M., Mootha, Vamsi K., Seidman, J. G., Seidman, Christine E.

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Genomic analyses implicate noncoding de novo variants in congenital heart disease von Richter, Felix, Morton, Sarah U., Kim, Seong Won, Kitaygorodsky, Alexander, Wasson, Lauren K., Chen, Kathleen M., Zhou, Jian, Qi, Hongjian, Patel, Nihir, DePalma, Steven R., Parfenov, Michael, Homsy, Jason, Gorham, Joshua M., Manheimer, Kathryn B., Velinder, Matthew, Farrell, Andrew, Marth, Gabor, Schadt, Eric E., Kaltman, Jonathan R., Newburger, Jane W., Giardini, Alessandro, Goldmuntz, Elizabeth, Brueckner, Martina, Kim, Richard, Porter, George A., Bernstein, Daniel, Chung, Wendy K., Srivastava, Deepak, Tristani-Firouzi, Martin, Troyanskaya, Olga G., Dickel, Diane E., Shen, Yufeng, Seidman, Jonathan G., Seidman, Christine E., Gelb, Bruce D.

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Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β von Teekakirikul, Polakit, Eminaga, Seda, Toka, Okan, Alcalai, Ronny, Wang, Libin, Wakimoto, Hiroko, Nayor, Matthew, Konno, Tetsuo, Gorham, Joshua M, Wolf, Cordula M, Kim, Jae B, Schmitt, Joachim P, Molkentin, Jefferey D, Norris, Russell A, Tager, Andrew M, Hoffman, Stanley R, Markwald, Roger R, Seidman, Christine E, Seidman, Jonathan G

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Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing von Ito, Kaoru, Patel, Parth N., Gorham, Joshua M., McDonough, Barbara, DePalma, Steven R., Adler, Emily E., Lam, Lien, MacRae, Calum A., Mohiuddin, Syed M., Fatkin, Diane, Seidman, Christine E., Seidman, J. G.

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Functional dissection of human cardiac enhancers and noncoding de novo variants in congenital heart disease von Xiao, Feng, Zhang, Xiaoran, Morton, Sarah U., Kim, Seong Won, Fan, Youfei, Gorham, Joshua M., Zhang, Huan, Berkson, Paul J., Mazumdar, Neil, Cao, Yangpo, Chen, Jian, Hagen, Jacob, Liu, Xujie, Zhou, Pingzhu, Richter, Felix, Shen, Yufeng, Ward, Tarsha, Gelb, Bruce D., Seidman, Jonathan G., Seidman, Christine E., Pu, William T.

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Glycogen Storage Diseases Presenting as Hypertrophic Cardiomyopathy von Arad, Michael, Maron, Barry J, Gorham, Joshua M, Johnson, Walter H, Saul, J. Philip, Perez-Atayde, Antonio R, Spirito, Paolo, Wright, Gregory B, Kanter, Ronald J, Seidman, J.G, Seidman, Christine E

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Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development von Lage, Kasper, Greenway, Steven C, Rosenfeld, Jill A, Wakimoto, Hiroko, Gorham, Joshua M, Segrè, Ayellet V, Roberts, Amy E, Smoot, Leslie B, Pu, William T, C. Pereira, Alexandre, Mesquita, Sonia M, Tommerup, Niels, Brunak, Søren, Ballif, Blake C, Shaffer, Lisa G, Donahoe, Patricia K, Daly, Mark J, Seidman, Jonathan G, Seidman, Christine E, Larsen, Lars A

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Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis von Jiang, Jianming, Patrick G. Burgon, Hiroko Wakimoto, Kenji Onoue, Joshua M. Gorham, Caitlin C. O’Meara, Gregory Fomovsky, Bradley K. McConnell, Richard T. Lee, J. G. Seidman, Christine E. Seidman

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Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors von Atsuta, Yuji, Lee, ChangHee, Rodrigues, Alan R, Colle, Charlotte, Tomizawa, Reiko R, Lujan, Ernesto G, Tschopp, Patrick, Galan, Laura, Zhu, Meng, Gorham, Joshua M, Vannier, Jean-Pierre, Seidman, Christine E, Seidman, Jonathan G, Ros, Marian A, Pourquié, Olivier, Tabin, Clifford J

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Neither cardiac mitochondrial DNA variation nor copy number contribute to congenital heart disease risk von Willcox, Jon A L, Geiger, Joshua T, Morton, Sarah U, McKean, David, Quiat, Daniel, Gorham, Joshua M, Tai, Angela C, DePalma, Steven, Bernstein, Daniel, Brueckner, Martina, Chung, Wendy K, Giardini, Alessandro, Goldmuntz, Elizabeth, Kaltman, Jonathan R, Kim, Richard, Newburger, Jane W, Shen, Yufeng, Srivastava, Deepak, Tristani-Firouzi, Martin, Gelb, Bruce, Porter, Jr, George A, Seidman, J G, Seidman, Christine E

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Increased endothelial sclerostin caused by elevated DSCAM mediates multiple trisomy 21 phenotypes von McKean, David M, Zhang, Qi, Narayan, Priyanka, Morton, Sarah U, Strohmenger, Viktoria, Tang, Vi T, McAllister, Sophie, Sharma, Ananya, Quiat, Daniel, Reichart, Daniel, DeLaughter, Daniel M, Wakimoto, Hiroko, Gorham, Joshua M, Brown, Kemar, McDonough, Barbara, Willcox, Jon A, Jang, Min Young, DePalma, Steven R, Ward, Tarsha, Kim, Richard, Cleveland, John D, Seidman, J G, Seidman, Christine E

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