Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions von Joseph, Prem Raj B, Mosier, Philip D, Desai, Umesh R, Rajarathnam, Krishna

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Proline Substitution of Dimer Interface β-strand Residues as a Strategy for the Design of Functional Monomeric Proteins von Joseph, Prem Raj B., Poluri, Krishna Mohan, Gangavarapu, Pavani, Rajagopalan, Lavanya, Raghuwanshi, Sandeep, Richardson, Ricardo M., Garofalo, Roberto P., Rajarathnam, Krishna

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Glycosaminoglycan Interactions Fine-Tune Chemokine-Mediated Neutrophil Trafficking: Structural Insights and Molecular Mechanisms von Rajarathnam, Krishna, Sepuru, Krishna Mohan, Joseph, Prem Raj B., Sawant, Kirti V., Brown, Aaron J.

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Dynamics-Derived Insights into Complex Formation between the CXCL8 Monomer and CXCR1 N-Terminal Domain: An NMR Study von Joseph, Prem Raj B, Spyracopoulos, Leo, Rajarathnam, Krishna

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Heparin-bound chemokine CXCL8 monomer and dimer are impaired for CXCR1 and CXCR2 activation: implications for gradients and neutrophil trafficking von Joseph, Prem Raj B., Sawant, Kirti V., Rajarathnam, Krishna

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Dynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation von Joseph, Prem Raj B, Sawant, Kirti V, Isley, Angela, Pedroza, Mesias, Garofalo, Roberto P, Richardson, Ricardo M, Rajarathnam, Krishna

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A conserved annexin A6–mediated membrane repair mechanism in muscle, heart, and nerve von Demonbreun, Alexis R., Bogdanovic, Elena, Vaught, Lauren A., Reiser, Nina L., Fallon, Katherine S., Long, Ashlee M., Oosterbaan, Claire C., Hadhazy, Michele, Page, Patrick G.T., Joseph, Prem Raj B., Cowen, Gabrielle, Telenson, Alexander M., Khatri, Ammaarah, Sadleir, Katherine R., Vassar, Robert, McNally, Elizabeth M.

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Probing the Role of CXC Motif in Chemokine CXCL8 for High Affinity Binding and Activation of CXCR1 and CXCR2 Receptors[S] von Joseph, Prem Raj B., Sarmiento, Jose M., Mishra, Anurag K., Das, Sandhya T., Garofalo, Roberto P., Navarro, Javier, Rajarathnam, Krishna

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Solution NMR characterization of WT CXCL8 monomer and dimer binding to CXCR1 N‐terminal domain von Joseph, Prem Raj B., Rajarathnam, Krishna

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Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease von Bratkowski, Matthew, Burdett, Thomas C., Danao, Jean, Wang, Xidao, Mathur, Prakhyat, Gu, Weijing, Beckstead, Jennifer A., Talreja, Santosh, Yang, Yu-San, Danko, Gregory, Park, Jae Hong, Walton, Mary, Brown, Sean P., Tegley, Christopher M., Joseph, Prem Raj B., Reynolds, Charles H., Sambashivan, Shilpa

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Molecular Basis of Glycosaminoglycan Heparin Binding to the Chemokine CXCL1 Dimer von Poluri, Krishna Mohan, Joseph, Prem Raj B., Sawant, Kirti V., Rajarathnam, Krishna

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The p12 domain is unstructured in a murine leukemia virus p12-CA(N) Gag construct von Kyere, Sampson K, Joseph, Prem Raj B, Summers, Michael F

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Chemokine CXCL7 Heterodimers: Structural Insights, CXCR2 Receptor Function, and Glycosaminoglycan Interactions von Brown, Aaron J, Joseph, Prem Raj B, Sawant, Kirti V, Rajarathnam, Krishna

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Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions von Joseph, Prem Raj B., Sawant, Kirti V., Iwahara, Junji, Garofalo, Roberto P., Desai, Umesh R., Rajarathnam, Krishna

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Structural Basis for Differential Binding of the Interleukin-8 Monomer and Dimer to the CXCR1 N-Domain: Role of Coupled Interactions and Dynamics von Ravindran, Aishwarya, Joseph, Prem Raj B, Rajarathnam, Krishna

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Characterizing Protein–Glycosaminoglycan Interactions Using Solution NMR Spectroscopy von Joseph, Prem Raj B., Poluri, Krishna Mohan, Sepuru, Krishna Mohan, Rajarathnam, Krishna

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Structural characterization of BRCT–tetrapeptide binding interactions von Joseph, Prem Raj B., Yuan, Ziyan, Kumar, Eric A., Lokesh, G.L., Kizhake, Smitha, Rajarathnam, Krishna, Natarajan, Amarnath

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The p12 Domain Is Unstructured in a Murine Leukemia Virus p12-CAN Gag Construct von Kyere, Sampson K., Joseph, Prem Raj B., Summers, Michael F.

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Solution NMR characterization of WT CXCL 8 monomer and dimer binding to CXCR 1 N ‐terminal domain von Joseph, Prem Raj B., Rajarathnam, Krishna

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Glycosaminoglycans: Methods and Protocols von Balagurunathan, Kuberan, Nakato, Hiroshi, Desai, Umesh, Saijoh, Yukio

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