Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens von Williams, Andrew R, Douglas, Alexander D, Miura, Kazutoyo, Illingworth, Joseph J, Choudhary, Prateek, Murungi, Linda M, Furze, Julie M, Diouf, Ababacar, Miotto, Olivo, Crosnier, Cécile, Wright, Gavin J, Kwiatkowski, Dominic P, Fairhurst, Rick M, Long, Carole A, Draper, Simon J

Volltext

A PfRH5-Based Vaccine Is Efficacious against Heterologous Strain Blood-Stage Plasmodium falciparum Infection in Aotus Monkeys von Douglas, Alexander D., Baldeviano, G. Christian, Lucas, Carmen M., Lugo-Roman, Luis A., Crosnier, Cécile, Bartholdson, S. Josefin, Diouf, Ababacar, Miura, Kazutoyo, Lambert, Lynn E., Ventocilla, Julio A., Leiva, Karina P., Milne, Kathryn H., Illingworth, Joseph J., Spencer, Alexandra J., Hjerrild, Kathryn A., Alanine, Daniel G.W., Turner, Alison V., Moorhead, Jeromy T., Edgel, Kimberly A., Wu, Yimin, Long, Carole A., Wright, Gavin J., Lescano, Andrés G., Draper, Simon J.

Volltext

Heterotypic interactions drive antibody synergy against a malaria vaccine candidate von Ragotte, Robert J., Pulido, David, Lias, Amelia M., Quinkert, Doris, Alanine, Daniel G. W., Jamwal, Abhishek, Davies, Hannah, Nacer, Adéla, Lowe, Edward D., Grime, Geoffrey W., Illingworth, Joseph J., Donat, Robert F., Garman, Elspeth F., Bowyer, Paul W., Higgins, Matthew K., Draper, Simon J.

Volltext

Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies von Wright, Katherine E., Hjerrild, Kathryn A., Bartlett, Jonathan, Douglas, Alexander D., Jin, Jing, Brown, Rebecca E., Illingworth, Joseph J., Ashfield, Rebecca, Clemmensen, Stine B., de Jongh, Willem A., Draper, Simon J., Higgins, Matthew K.

Volltext

Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies von Alanine, Daniel G.W., Quinkert, Doris, Kumarasingha, Rasika, Mehmood, Shahid, Donnellan, Francesca R., Minkah, Nana K., Dadonaite, Bernadeta, Diouf, Ababacar, Galaway, Francis, Silk, Sarah E., Jamwal, Abhishek, Marshall, Jennifer M., Miura, Kazutoyo, Foquet, Lander, Elias, Sean C., Labbé, Geneviève M., Douglas, Alexander D., Jin, Jing, Payne, Ruth O., Illingworth, Joseph J., Pattinson, David J., Pulido, David, Williams, Barnabas G., de Jongh, Willem A., Wright, Gavin J., Kappe, Stefan H.I., Robinson, Carol V., Long, Carole A., Crabb, Brendan S., Gilson, Paul R., Higgins, Matthew K., Draper, Simon J.

Volltext

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody von Douglas, Alexander D., Williams, Andrew R., Illingworth, Joseph J., Kamuyu, Gathoni, Biswas, Sumi, Goodman, Anna L., Wyllie, David H., Crosnier, Cécile, Miura, Kazutoyo, Wright, Gavin J., Long, Carole A., Osier, Faith H., Marsh, Kevin, Turner, Alison V., Hill, Adrian V.S., Draper, Simon J.

Volltext

Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5 von Douglas, Alexander D, Williams, Andrew R, Knuepfer, Ellen, Illingworth, Joseph J, Furze, Julie M, Crosnier, Cécile, Choudhary, Prateek, Bustamante, Leyla Y, Zakutansky, Sara E, Awuah, Dennis K, Alanine, Daniel G W, Theron, Michel, Worth, Andrew, Shimkets, Richard, Rayner, Julian C, Holder, Anthony A, Wright, Gavin J, Draper, Simon J

Volltext

Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-Naive Individuals von Hodgson, Susanne H., Ewer, Katie J., Bliss, Carly M., Edwards, Nick J., Rampling, Thomas, Anagnostou, Nicholas A., de Barra, Eoghan, Havelock, Tom, Bowyer, Georgina, Poulton, Ian D., de Cassan, Simone, Longley, Rhea, Illingworth, Joseph J., Douglas, Alexander D., Mange, Pooja B., Collins, Katharine A., Roberts, Rachel, Gerry, Stephen, Berrie, Eleanor, Moyle, Sarah, Colloca, Stefano, Cortese, Riccardo, Sinden, Robert E., Gilbert, Sarah C., Bejon, Philip, Lawrie, Alison M., Nicosia, Alfredo, Faust, Saul N., Hill, Adrian V. S.

Volltext

Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex von Williams, Barnabas G., King, Lloyd D. W., Pulido, David, Quinkert, Doris, Lias, Amelia M., Silk, Sarah E., Ragotte, Robert J., Davies, Hannah, Barrett, Jordan R., McHugh, Kirsty, Rigby, Cassandra A., Alanine, Daniel G. W., Barfod, Lea, Shea, Michael W., Cowley, Li An, Dabbs, Rebecca A., Pattinson, David J., Douglas, Alexander D., Lyth, Oliver R., Illingworth, Joseph J., Jin, Jing, Carnrot, Cecilia, Kotraiah, Vinayaka, Christen, Jayne M., Noe, Amy R., MacGill, Randall S., King, C. Richter, Birkett, Ashley J., Soisson, Lorraine A., Skinner, Katherine, Miura, Kazutoyo, Long, Carole A., Higgins, Matthew K., Draper, Simon J.

Volltext

Functional Characterization and Comparison of Plasmodium falciparum Proteins as Targets of Transmission-blocking Antibodies von Nikolaeva, Daria, Illingworth, Joseph J., Miura, Kazutoyo, Alanine, Daniel G.W., Brian, Iona J., Li, Yuanyuan, Fyfe, Alex J., Da, Dari F., Cohuet, Anna, Long, Carole A., Draper, Simon J., Biswas, Sumi

Volltext

Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system von Hjerrild, Kathryn A., Jin, Jing, Wright, Katherine E., Brown, Rebecca E., Marshall, Jennifer M., Labbé, Geneviève M., Silk, Sarah E., Cherry, Catherine J., Clemmensen, Stine B., Jørgensen, Thomas, Illingworth, Joseph J., Alanine, Daniel G. W., Milne, Kathryn H., Ashfield, Rebecca, de Jongh, Willem A., Douglas, Alexander D., Higgins, Matthew K., Draper, Simon J.

Volltext

Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens von Illingworth, Joseph J, Alanine, Daniel G, Brown, Rebecca, Marshall, Jennifer M, Bartlett, Helen E, Silk, Sarah E, Labbé, Geneviève M, Quinkert, Doris, Cho, Jee Sun, Wendler, Jason P, Pattinson, David J, Barfod, Lea, Douglas, Alexander D, Shea, Michael W, Wright, Katherine E, de Cassan, Simone C, Higgins, Matthew K, Draper, Simon J

Volltext

Progress with viral vectored malaria vaccines: A multi-stage approach involving “unnatural immunity” von Ewer, Katie J, Sierra-Davidson, Kailan, Salman, Ahmed M, Illingworth, Joseph J, Draper, Simon J, Biswas, Sumi, Hill, Adrian V.S

Volltext

Long‐lived Plasmodium falciparum specific memory B cells in naturally exposed Swedish travelers von Ndungu, Francis M., Lundblom, Klara, Rono, Josea, Illingworth, Joseph, Eriksson, Sara, Färnert, Anna

Volltext

Combining Viral Vectored and Protein-in-adjuvant Vaccines Against the Blood-stage Malaria Antigen AMA1: Report on a Phase 1a Clinical Trial von Hodgson, Susanne H, Choudhary, Prateek, Elias, Sean C, Milne, Kathryn H, Rampling, Thomas W, Biswas, Sumi, Poulton, Ian D, Miura, Kazutoyo, Douglas, Alexander D, Alanine, Daniel GW, Illingworth, Joseph J, de Cassan, Simone C, Zhu, Daming, Nicosia, Alfredo, Long, Carole A, Moyle, Sarah, Berrie, Eleanor, Lawrie, Alison M, Wu, Yimin, Ellis, Ruth D, Hill, Adrian V S, Draper, Simon J

Volltext

Dissecting T‐cell activation with high‐resolution live‐cell microscopy von Illingworth, Joseph J., van der Merwe, P. Anton

Volltext

Chronic exposure to Plasmodium falciparum is associated with phenotypic evidence of B and T cell exhaustion von Illingworth, Joseph, Butler, Noah S, Roetynck, Sophie, Mwacharo, Jedida, Pierce, Susan K, Bejon, Philip, Crompton, Peter D, Marsh, Kevin, Ndungu, Francis M

Volltext

Long‐lived P lasmodium falciparum specific memory B cells in naturally exposed S wedish travelers von Ndungu, Francis M., Lundblom, Klara, Rono, Josea, Illingworth, Joseph, Eriksson, Sara, Färnert, Anna

Volltext

Progress towards a broadly neutralizing vaccine against the asexual blood-stage of Plasmodium falciparum von Alexander, Douglas, Andrew, Williams, Joseph, Illingworth, Kathryn, Hjerrild, Simon, Draper

Volltext

Functional Characterization and Comparison of Plasmodium falciparum Proteins as Targets of Transmission-blocking Antibodies von Nikolaeva, Daria, Illingworth, Joseph J, Miura, Kazutoyo, Alanine, Daniel G W, Brian, Iona J, Li, Yuanyuan, Fyfe, Alex J, Da, Dari F, Cohuet, Anna, Long, Carole A, Draper, Simon J, Biswas, Sumi

Volltext