Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer von Al-Ahmadie, Hikmat A, Iyer, Gopa, Lee, Byron H, Scott, Sasinya N, Mehra, Rohit, Bagrodia, Aditya, Jordan, Emmet J, Gao, Sizhi Paul, Ramirez, Ricardo, Cha, Eugene K, Desai, Neil B, Zabor, Emily C, Ostrovnaya, Irina, Gopalan, Anuradha, Chen, Ying-Bei, Fine, Samson W, Tickoo, Satish K, Gandhi, Anupama, Hreiki, Joseph, Viale, Agnès, Arcila, Maria E, Dalbagni, Guido, Rosenberg, Jonathan E, Bochner, Bernard H, Bajorin, Dean F, Berger, Michael F, Reuter, Victor E, Taylor, Barry S, Solit, David B

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Prospective Comprehensive Molecular Characterization of Lung Adenocarcinomas for Efficient Patient Matching to Approved and Emerging Therapies von Jordan, Emmet J, Kim, Hyunjae R, Arcila, Maria E, Barron, David, Chakravarty, Debyani, Gao, JianJiong, Chang, Matthew T, Ni, Andy, Kundra, Ritika, Jonsson, Philip, Jayakumaran, Gowtham, Gao, Sizhi Paul, Johnsen, Hannah C, Hanrahan, Aphrothiti J, Zehir, Ahmet, Rekhtman, Natasha, Ginsberg, Michelle S, Li, Bob T, Yu, Helena A, Paik, Paul K, Drilon, Alexander, Hellmann, Matthew D, Reales, Dalicia N, Benayed, Ryma, Rusch, Valerie W, Kris, Mark G, Chaft, Jamie E, Baselga, José, Taylor, Barry S, Schultz, Nikolaus, Rudin, Charles M, Hyman, David M, Berger, Michael F, Solit, David B, Ladanyi, Marc, Riely, Gregory J

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Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms von Lowery, Maeve A, Wong, Winston, Jordan, Emmet J, Lee, Jonathan W, Kemel, Yelena, Vijai, Joseph, Mandelker, Diana, Zehir, Ahmet, Capanu, Marinela, Salo-Mullen, Erin, Arnold, Angela G, Yu, Kenneth H, Varghese, Anna M, Kelsen, David P, Brenner, Robin, Kaufmann, Erica, Ravichandran, Vignesh, Mukherjee, Semanti, Berger, Michael F, Hyman, David M, Klimstra, David S, Abou-Alfa, Ghassan K, Tjan, Catherine, Covington, Christina, Maynard, Hannah, Allen, Peter J, Askan, Gokce, Leach, Steven D, Iacobuzio-Donahue, Christine A, Robson, Mark E, Offit, Kenneth, Stadler, Zsofia K, O'Reilly, Eileen M

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ERCC2 Helicase Domain Mutations Confer Nucleotide Excision Repair Deficiency and Drive Cisplatin Sensitivity in Muscle-Invasive Bladder Cancer von Li, Qiang, Damish, Alexis W, Frazier, Zoë, Liu, David, Reznichenko, Elizaveta, Kamburov, Atanas, Bell, Andrew, Zhao, Huiyong, Jordan, Emmet J, Gao, S Paul, Ma, Jennifer, Abbosh, Philip H, Bellmunt, Joaquim, Plimack, Elizabeth R, Lazaro, Jean-Bernard, Solit, David B, Bajorin, Dean, Rosenberg, Jonathan E, D'Andrea, Alan D, Riaz, Nadeem, Van Allen, Eliezer M, Iyer, Gopa, Mouw, Kent W

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Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype von Lowery, Maeve A, Jordan, Emmet J, Basturk, Olca, Ptashkin, Ryan N, Zehir, Ahmet, Berger, Michael F, Leach, Tanisha, Herbst, Brian, Askan, Gokce, Maynard, Hannah, Glassman, Danielle, Covington, Christina, Schultz, Nikolaus, Abou-Alfa, Ghassan K, Harding, James J, Klimstra, David S, Hechtman, Jaclyn F, Hyman, David M, Allen, Peter J, Jarnagin, William R, Balachandran, Vinod P, Varghese, Anna M, Schattner, Mark A, Yu, Kenneth H, Saltz, Leonard B, Solit, David B, Iacobuzio-Donahue, Christine A, Leach, Steven D, O'Reilly, Eileen M

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Frequency and outcomes of brain metastases in patients with HER2‐mutant lung cancers von Offin, Michael, Feldman, Daniel, Ni, Ai, Myers, Mackenzie L., Lai, W. Victoria, Pentsova, Elena, Boire, Adrienne, Daras, Mariza, Jordan, Emmet J., Solit, David B., Arcila, Maria E., Jones, David R., Isbell, James M., Beal, Kathryn, Young, Robert J., Rudin, Charles M., Riely, Gregory J., Drilon, Alexander, Tabar, Viviane, DeAngelis, Lisa M., Yu, Helena A., Kris, Mark G., Li, Bob T.

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Evaluation of ABT-751, a novel anti-mitotic agent able to overcome multi-drug resistance, in melanoma cells von Mahgoub, Thamir M., Jordan, Emmet J., Mahdi, Amira F., Oettl, Veronika, Huefner, Stefanie, O’Donovan, Norma, Crown, John, Collins, Denis M.

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YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics von Fan, Pang-Dian, Narzisi, Giuseppe, Jayaprakash, Anitha D., Venturini, Elisa, Robine, Nicolas, Smibert, Peter, Germer, Soren, Yu, Helena A., Jordan, Emmet J., Paik, Paul K., Janjigian, Yelena Y., Chaft, Jamie E., Wang, Lu, Jungbluth, Achim A., Middha, Sumit, Spraggon, Lee, Qiao, Huan, Lovly, Christine M., Kris, Mark G., Riely, Gregory J., Politi, Katerina, Varmus, Harold, Ladanyi, Marc

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Pregnancy-associated breast cancer: evaluating maternal and foetal outcomes. A national study von Prior, Lisa, O’Dwyer, Richard, Farooq, Abdul Rehman, Greally, Megan, Ward, Cian, O’Leary, Connor, Aslam, Razia, Darwish, Waseem, Ahmed, Nada, Othman, Elly Che, Watson, Geoffrey, Kelly, Deirdre, Gleeson, Jack, Kiely, Lisa, Hassan, Anees, Walsh, Elaine M., O’Reilly, David, Jones, Alfred, Featherstone, Hannah, Lim, Marvin, Murray, Hazel, Hennessy, Bryan T., Smyth, Lillian M., Leonard, Gregory, Grogan, Liam, Breathnach, Oscar, Calvert, Paula, Horgan, Anne M., Coate, Linda, Jordan, Emmet J., O’Mahony, Deirdre, Gupta, Rajnish, Keane, Maccon M., Westrup, Jennifer, Duffy, Karen, O’Connor, Miriam, Morris, Patrick G., Kennedy, M. John, O’Reilly, Seamus, McCaffrey, John, Kelly, Catherine M., Carney, Desmond, Gullo, Giuseppe, Crown, John, Higgins, Michaela J., Walsh, Paul M., Walshe, Janice M.

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Brain Metastases in Pancreatic Ductal Adenocarcinoma: Assessment of Molecular Genotype–Phenotype Features—An Entity With an Increasing Incidence? von Jordan, Emmet J., Lowery, Maeve A., Basturk, Olca, Allen, Peter J., Yu, Kenneth H., Tabar, Viviane, Beal, Kathryn, Reidy, Diane L., Yamada, Yoshiya, Janjigian, Yelena, Abou-Alfa, Ghassan K., O'Reilly, Eileen M.

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Case report: primary acinar cell carcinoma of the liver treated with multimodality therapy von Jordan, Emmet J, Basturk, Olca, Shia, Jinru, Klimstra, David S, Alago, William, D'Angelica, Michael I, Abou-Alfa, Ghassan K, O'Reilly, Eileen M, Lowery, Maeve A

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Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients von Zehir, Ahmet, Benayed, Ryma, Shah, Ronak H, Syed, Aijazuddin, Middha, Sumit, Kim, Hyunjae R, Srinivasan, Preethi, Gao, Jianjiong, Chakravarty, Debyani, Devlin, Sean M, Hellmann, Matthew D, Barron, David A, Schram, Alison M, Hameed, Meera, Dogan, Snjezana, Ross, Dara S, Hechtman, Jaclyn F, DeLair, Deborah F, Yao, JinJuan, Mandelker, Diana L, Cheng, Donavan T, Chandramohan, Raghu, Mohanty, Abhinita S, Ptashkin, Ryan N, Jayakumaran, Gowtham, Prasad, Meera, Syed, Mustafa H, Rema, Anoop Balakrishnan, Liu, Zhen Y, Nafa, Khedoudja, Borsu, Laetitia, Sadowska, Justyna, Casanova, Jacklyn, Bacares, Ruben, Kiecka, Iwona J, Razumova, Anna, Son, Julie B, Stewart, Lisa, Baldi, Tessara, Mullaney, Kerry A, Al-Ahmadie, Hikmat, Vakiani, Efsevia, Abeshouse, Adam A, Penson, Alexander V, Jonsson, Philip, Camacho, Niedzica, Chang, Matthew T, Won, Helen H, Gross, Benjamin E, Kundra, Ritika, Heins, Zachary J, Chen, Hsiao-Wei, Phillips, Sarah, Zhang, Hongxin, Wang, Jiaojiao, Ochoa, Angelica, Wills, Jonathan, Eubank, Michael, Thomas, Stacy B, Gardos, Stuart M, Reales, Dalicia N, Galle, Jesse, Durany, Robert, Cambria, Roy, Abida, Wassim, Cercek, Andrea, Feldman, Darren R, Gounder, Mrinal M, Hakimi, A Ari, Harding, James J, Iyer, Gopa, Janjigian, Yelena Y, Jordan, Emmet J, Kelly, Ciara M, Lowery, Maeve A, Morris, Luc G T, Omuro, Antonio M, Raj, Nitya, Razavi, Pedram, Shoushtari, Alexander N, Shukla, Neerav, Soumerai, Tara E, Varghese, Anna M, Yaeger, Rona, Coleman, Jonathan, Bochner, Bernard, Riely, Gregory J, Saltz, Leonard B, Scher, Howard I, Sabbatini, Paul J, Robson, Mark E, Klimstra, David S, Taylor, Barry S, Baselga, Jose, Schultz, Nikolaus, Hyman, David M, Arcila, Maria E, Solit, David B, Ladanyi, Marc, Berger, Michael F

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Case report: primary acinar cell carcinoma of the liver treated with multimodality therapy von Jordan, Emmet J, Basturk, Olca, Shia, Jinru, Klimstra, David S, Alago, William, D'Angelica, Michael I, Abou-Alfa, Ghassan K, O'Reilly, Eileen M, Lowery, Maeve A

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Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for Intervention von Lowery, Maeve A, Ptashkin, Ryan, Jordan, Emmet, Berger, Michael F, Zehir, Ahmet, Capanu, Marinela, Kemeny, Nancy E, O'Reilly, Eileen M, El-Dika, Imane, Jarnagin, William R, Harding, James J, D'Angelica, Michael I, Cercek, Andrea, Hechtman, Jaclyn F, Solit, David B, Schultz, Nikolaus, Hyman, David M, Klimstra, David S, Saltz, Leonard B, Abou-Alfa, Ghassan K

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Concurrent Alterations in EGFR-Mutant Lung Cancers Associated with Resistance to EGFR Kinase Inhibitors and Characterization of MTOR as a Mediator of Resistance von Yu, Helena A, Suzawa, Ken, Jordan, Emmet, Zehir, Ahmet, Ni, Ai, Kim, Ryan, Kris, Mark G, Hellmann, Matthew D, Li, Bob T, Somwar, Romel, Solit, David B, Berger, Michael F, Arcila, Maria, Riely, Gregory J, Ladanyi, Marc

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Systemic anti-cancer therapy in older patients with gastrointestinal malignancies following comprehensive geriatric assessment: An age-based subgroup analysis von Goggin, Caitriona, Walsh, Darren J, Hannan, Michelle, Buckley, Carol, Jordan, Emmet, Calvert, Paula, O'Connor, Miriam, Horgan, Anne

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Second‐line chemotherapy in advanced biliary cancers: A retrospective, multicenter analysis of outcomes von Lowery, Maeve A., Goff, Laura W., Keenan, Bridget P., Jordan, Emmet, Wang, Rui, Bocobo, Andrea G., Chou, Joanne F., O’Reilly, Eileen M., Harding, James J., Kemeny, Nancy, Capanu, Marianela, Griffin, Ann C., McGuire, Joseph, Venook, Alan P., Abou‐Alfa, Ghassan K., Kelley, Robin K.

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AKT1 E17K Inhibits Cancer Cell Migration by Abrogating beta-Catenin Signaling von Gao, Sizhi Paul, Kiliti, Amber J., Zhang, Kai, Vasani, Naresh, Mao, Ninghui, Jordan, Emmet, Wise, Hannah C., Bhattarai, Tripti Shrestha, Hu, Wenhuo, Dorso, Madeline, Rodrigues, James A., Kim, Kwanghee, Hanrahan, Aphrothiti J., Razavi, Pedram, Carver, Brett, Chandarlapaty, Sarat, Reis-Filho, Jorge S., Taylor, Barry S., Solit, David B.

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The phenotype of spontaneous preterm birth: application of a clinical phenotyping tool von Manuck, Tracy A., MD, Esplin, M. Sean, MD, Biggio, Joseph, MD, Bukowski, Radek, MD, Parry, Samuel, MD, Zhang, Heping, PhD, Huang, Hao, PhD, Varner, Michael W., MD, Andrews, William, MD, Saade, George, MD, Sadovsky, Yoel, MD, Reddy, Uma M., MD, MPH, Ilekis, John, PhD

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Treatment and outcomes of small cell neuroendocrine carcinoma of the cervix (SCCC) von Schlappe, Brooke, Jordan, Emmet, Zhou, Qin, Iasonos, Alexia, Leitao, Mario M., Park, Kay J., Alektiar, Kaled M., Zivanovic, Oliver, Sabbatini, Paul, Aghajanian, Carol, O'Cearbhaill, Roisin Eilish

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