Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders von Cisar, Justin S, Weber, Olivia D, Clapper, Jason R, Blankman, Jacqueline L, Henry, Cassandra L, Simon, Gabriel M, Alexander, Jessica P, Jones, Todd K, Ezekowitz, R. Alan B, O’Neill, Gary P, Grice, Cheryl A

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Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators von Clapper, Jason R., Henry, Cassandra L., Niphakis, Micah J., Knize, Anna M., Coppola, Aundrea R., Simon, Gabriel M., Ngo, Nhi, Herbst, Rachel A., Herbst, Dylan M., Reed, Alex W., Cisar, Justin S., Weber, Olivia D., Viader, Andreu, Alexander, Jessica P., Cunningham, Mark L., Jones, Todd K., Fraser, Iain P., Grice, Cheryl A., Ezekowitz, R. Alan B., O’Neill, Gary P., Blankman, Jacqueline L.

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A One-Step Synthesis of 2,4-Unsubstituted Quinoline-3-carboxylic Acid Esters from o-Nitrobenzaldehydes von Venkatesan, Hariharan, Hocutt, Frances M, Jones, Todd K, Rabinowitz, Michael H

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Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones von van Oeveren, Arjan, Pio, Barbara A., Tegley, Christopher M., Higuchi, Robert I., Wu, Min, Jones, Todd K., Marschke, Keith B., Negro-Vilar, Andrés, Zhi, Lin

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Synthesis and Biological Activity of a Novel Series of Nonsteroidal, Peripherally Selective Androgen Receptor Antagonists Derived from 1,2-Dihydropyridono[5,6-g]quinolines von Hamann, Lawrence G, Higuchi, Robert I, Zhi, Lin, Edwards, James P, Wang, Xiao-Ning, Marschke, Keith B, Kong, James W, Farmer, Luc J, Jones, Todd K

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Library Enhancement through the Wisdom of Crowds von Hack, Michael D, Rassokhin, Dmitrii N, Buyck, Christophe, Seierstad, Mark, Skalkin, Andrew, ten Holte, Peter, Jones, Todd K, Mirzadegan, Taraneh, Agrafiotis, Dimitris K

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Inhibition of Fructose-1,6-bisphosphatase by a New Class of Allosteric Effectors von Choe, Jun-Young, Nelson, Scott W., Arienti, Kristen L., Axe, Frank U., Collins, Tassie L., Jones, Todd K., Kimmich, Rachel D.A., Newman, Michael J., Norvell, Karl, Ripka, William C., Romano, Suzanne J., Short, Kevin M., Slee, Deborah H., Fromm, Herbert J., Honzatko, Richard B.

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Total synthesis of the macrolide antibiotic cytovaricin von Evans, David A, Kaldor, Stephen W, Jones, Todd K, Clardy, Jon, Stout, Thomas J

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Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: Synthesis and preliminary SAR analysis von Gomez, Laurent, Hack, Michael D., Wu, Jiejun, Wiener, John J.M., Venkatesan, Hari, Santillán, Alejandro, Pippel, Daniel J., Mani, Neelakandha, Morrow, Brian J., Motley, S. Timothy, Shaw, Karen Joy, Wolin, Ronald, Grice, Cheryl A., Jones, Todd K.

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A practical enantioselective synthesis of .alpha.,.alpha.-diaryl-2-pyrrolidinemethanol. Preparation and chemistry of the corresponding oxazaborolidines von Mathre, David J, Jones, Todd K, Xavier, Lyndon C, Blacklock, Thomas J, Reamer, Robert A, Mohan, Julie J, Jones, E. Tracy Turner, Hoogsteen, Karst, Baum, Mary W, Grabowski, E. J. J

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Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains von Wiener, John J.M., Gomez, Laurent, Venkatesan, Hariharan, Santillán, Alejandro, Allison, Brett D., Schwarz, Kimberly L., Shinde, Shirin, Tang, Liu, Hack, Michael D., Morrow, Brian J., Motley, S. Timothy, Goldschmidt, Raul M., Shaw, Karen Joy, Jones, Todd K., Grice, Cheryl A.

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Synthesis and biological activity of 5-methylidene 1,2-dihydrochromeno[3,4- f]quinoline derivatives as progesterone receptor modulators von Zhi, Lin, Tegley, Christopher M, Pio, Barbara, Edwards, James P, Jones, Todd K, Marschke, Keith B, Mais, Dale E, Risek, Boris, Schrader, William T

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Design of Concise, Scalable Route to a Cholecystokinin 1 (CCK 1) Receptor Antagonist von Liang, Jimmy T, Mani, Neelakandha S, Jones, Todd K

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Discovery and Preliminary SAR Studies of a Novel, Nonsteroidal Progesterone Receptor Antagonist Pharmacophore von Pooley, Charlotte L. F, Edwards, James P, Goldman, Mark E, Wang, Ming-Wei, Marschke, Keith B, Crombie, Diane L, Jones, Todd K

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Non-imidazole heterocyclic histamine H3 receptor antagonists von WENYING CHAI, BREITENBUCHER, J. Guy, JONES, Todd K, KWOK, Annette, XIAOBING LI, WONG, Victoria, CARRUTHERS, Nicholas I, LOVENBERG, Timothy W, MAZUR, Curt, WILSON, Sandy J, AXE, Frank U

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Chemistry of tricarbonyl hemiketals and application of Evans technology to the total synthesis of the immunosuppressant (-)-FK-506 von Jones, Todd K, Reamer, Robert A, Desmond, Richard, Mills, Sander G

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Novel Series of Potent, Nonsteroidal, Selective Androgen Receptor Modulators Based on 7H-[1,4]Oxazino[3,2-g]quinolin-7-ones von Higuchi, Robert I, Arienti, Kristen L, López, Francisco J, Mani, Neelakhanda S, Mais, Dale E, Caferro, Thomas R, Long, Yun Oliver, Jones, Todd K, Edwards, James P, Zhi, Lin, Schrader, William T, Negro-Vilar, Andrés, Marschke, Keith B

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Preparation, Resolution, and Biological Evaluation of 5-Aryl-1,2-dihydro-5H-chromeno[3,4-f]quinolines:  Potent, Orally Active, Nonsteroidal Progesterone Receptor Agonists von Edwards, James P, Zhi, Lin, Pooley, Charlotte L. F, Tegley, Christopher M, West, Sarah J, Wang, Ming-Wei, Gottardis, Marco M, Pathirana, Charles, Schrader, William T, Jones, Todd K

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5-Benzylidene-1,2-dihydrochromeno[3,4-f]quinolines as Selective Progesterone Receptor Modulators von Zhi, Lin, Tegley, Christopher M, Pio, Barbara, Edwards, James P, Motamedi, Mehrnouch, Jones, Todd K, Marschke, Keith B, Mais, Dale E, Risek, Boris, Schrader, William T

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Thioether acetamides as P3 binding elements for tetrahydropyrido-pyrazole cathepsin S inhibitors von Wiener, Danielle K., Lee-Dutra, Alice, Bembenek, Scott, Nguyen, Steven, Thurmond, Robin L., Sun, Siquan, Karlsson, Lars, Grice, Cheryl A., Jones, Todd K., Edwards, James P.

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