Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung von McLachlan, G, Davidson, H, Holder, E, Davies, L A, Pringle, I A, Sumner-Jones, S G, Baker, A, Tennant, P, Gordon, C, Vrettou, C, Blundell, R, Hyndman, L, Stevenson, B, Wilson, A, Doherty, A, Shaw, D J, Coles, R L, Painter, H, Cheng, S H, Scheule, R K, Davies, J C, Innes, J A, Hyde, S C, Griesenbach, U, Alton, E W F W, Boyd, A C, Porteous, D J, Gill, D R, Collie, D D S

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Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis von Alton, Eric W F W, Beekman, Jeffery M, Boyd, A Christopher, Brand, June, Carlon, Marianne S, Connolly, Mary M, Chan, Mario, Conlon, Sinead, Davidson, Heather E, Davies, Jane C, Davies, Lee A, Dekkers, Johanna F, Doherty, Ann, Gea-Sorli, Sabrina, Gill, Deborah R, Griesenbach, Uta, Hasegawa, Mamoru, Higgins, Tracy E, Hironaka, Takashi, Hyndman, Laura, McLachlan, Gerry, Inoue, Makoto, Hyde, Stephen C, Innes, J Alastair, Maher, Toby M, Moran, Caroline, Meng, Cuixiang, Paul-Smith, Michael C, Pringle, Ian A, Pytel, Kamila M, Rodriguez-Martinez, Andrea, Schmidt, Alexander C, Stevenson, Barbara J, Sumner-Jones, Stephanie G, Toshner, Richard, Tsugumine, Shu, Wasowicz, Marguerite W, Zhu, Jie

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CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression von Hyde, Stephen C, Pringle, Ian A, Abdullah, Syahril, Lawton, Anna E, Davies, Lee A, Varathalingam, Anusha, Nunez-Alonso, Graciela, Green, Anne-Marie, Bazzani, Reto P, Sumner-Jones, Stephanie G, Chan, Mario, Li, Hongyu, Yew, Nelson S, Cheng, Seng H, Christopher Boyd, A, Davies, Jane C, Griesenbach, Uta, Porteous, David J, Sheppard, David N, Munkonge, Felix M, Alton, Eric W F W, Gill, Deborah R

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Transgene sequences free of CG dinucleotides lead to high level, long-term expression in the lung independent of plasmid backbone design von Bazzani, Reto P, Pringle, Ian A, Connolly, Mary M, Davies, Lee A, Sumner-Jones, Stephanie G, Schleef, Martin, Hyde, Stephen C, Gill, Deborah R

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The use of CpG-free plasmids to mediate persistent gene expression following repeated aerosol delivery of pDNA/PEI complexes von Davies, Lee A, Hyde, Stephen C, Nunez-Alonso, Graciela, Bazzani, Reto P, Harding-Smith, Rebekka, Pringle, Ian A, Lawton, Anna E, Abdullah, Syahril, Roberts, Thomas C, McCormick, Dominique, Sumner-Jones, Stephanie G, Gill, Deborah R

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Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung von Alton, E W F W, Boyd, A C, Cheng, S H, Davies, J C, Davies, L A, Dayan, A, Gill, D R, Griesenbach, U, Higgins, T, Hyde, S C, Innes, J A, McLachlan, G, Porteous, D, Pringle, I, Scheule, R K, Sumner-Jones, S

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CpG-free plasmid expression cassettes for cystic fibrosis gene therapy von Pringle, Ian A, Hyde, Stephen C, Connolly, Mary M, Lawton, Anna E, Xu, Bihui, Nunez-Alonso, Graciela, Davies, Lee A, Sumner-Jones, Stephanie G, Gill, Deborah R

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Enhancing Fracture Detection in Remote Settings: Evaluating the Efficacy of FIXUS AI Deep Learning Algorithms in Identifying Fifth Metatarsal Fractures Using Mixed-Quality X-rays von Taseh, Atta, Gholipour, Alireza, Eftekhari, Mani, Ebrahimi, Alireza, Flaherty, Alexandra F., Jones, Sumner, Nukala, Varun, Waryasz, Gregory R., Guss, Daniel, Kwon, John Y., DiGiovanni, Christopher W., Bejarano-Pineda, Lorena, Ashkani-Esfahani, Soheil

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The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep von Alton, Eric W.F.W, Baker, Alison, Baker, Eilidh, Boyd, A. Christopher, Cheng, Seng H, Coles, Rebecca L, Collie, D. David S, Davidson, Heather, Davies, Jane C, Gill, Deborah R, Gordon, Catherine, Griesenbach, Uta, Higgins, Tracy, Hyde, Stephen C, Innes, J. Alastair, McCormick, Dominique, McGovern, Michael, McLachlan, Gerry, Porteous, David J, Pringle, Ian, Scheule, Ronald K, Shaw, Darren J, Smith, Sionagh, Sumner-Jones, Stephanie G, Tennant, Peter, Vrettou, Christina

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Long-term persistence of gene expression from adeno-associated virus serotype 5 in the mouse airways von Sumner-Jones, S G, Davies, L A, Varathalingam, A, Gill, D R, Hyde, S C

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Lack of Repeat Transduction by Recombinant Adeno-Associated Virus Type 5/5 Vectors in the Mouse Airway von SUMNER-JONES, Stephanie G, GILL, Deborah R, HYDE, Stephen C

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The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways von Griesenbach, Uta, Meng, Cuixiang, Farley, Raymond, Wasowicz, Marguerite Y, Munkonge, Felix M, Chan, Mario, Stoneham, Charlotte, Sumner-Jones, Stephanie G, Pringle, Ian A, Gill, Deborah R, Hyde, Stephen C, Stevenson, Barbara, Holder, Emma, Ban, Hiroshi, Hasegawa, Mamoru, Cheng, Seng H, Scheule, Ronald K, Sinn, Patrick L, McCray, Paul B, Alton, Eric W.F.W

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Enhanced Lung Gene Expression After Aerosol Delivery of Concentrated pDNA/PEI Complexes von Davies, Lee A, McLachlan, Gerry, Sumner-Jones, Stephanie G, Ferguson, David, Baker, Alison, Tennant, Peter, Gordon, Catherine, Vrettou, Christina, Baker, Eilidh, Zhu, Jie, Alton, Eric WFW, Collie, David DS, Porteous, David J, Hyde, Stephen C, Gill, Deborah R

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Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis von Clark, Kenneth L, Hughes, Stephen A, Bulsara, Pallav, Coates, Jill, Moores, Kitty, Parry, Joel, Carr, Michael, Mayer, Ruth J, Wilson, Paul, Gruenloh, Chris, Levin, Daren, Darton, Jill, Weber, Wolf-Michael, Sobczak, Katja, Gill, Deborah R, Hyde, Stephen C, Davies, Lee A, Pringle, Ian A, Sumner-Jones, Stephanie G, Jadhav, Vasant, Jamison, Sharon, Strapps, Walter R, Pickering, Victoria, Edbrooke, Mark R

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Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer von Griesenbach, Uta, Vicente, Catarina C, Roberts, Megan J, Meng, Cuixiang, Soussi, Samia, Xenariou, Stefania, Tennant, Peter, Baker, Alison, Baker, Eilidh, Gordon, Catherine, Vrettou, Christina, McCormick, Dominique, Coles, Rebecca, Green, Anne-Marie, Lawton, Anna E, Sumner-Jones, Stephanie G, Cheng, Seng H, Scheule, Ronald K, Hyde, Stephen C, Gill, Deborah R, Collie, David D, McLachlan, Gerry, Alton, Eric W.F.W

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Coating of adeno-associated virus with reactive polymers can ablate virus tropism, enable retargeting and provide resistance to neutralising antisera von Carlisle, Robert C., Benjamin, Reuben, Briggs, Simon S., Sumner-Jones, Stephanie, McIntosh, Jenny, Gill, Deborah, Hyde, Steve, Nathwani, Amit, Subr, Vladimir, Ulbrich, Karel, Seymour, Leonard W., Fisher, Kerry D.

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Electroporation enhances reporter gene expression following delivery of naked plasmid DNA to the lung von Pringle, Ian A., McLachlan, Gerry, Collie, David D. S., Sumner-Jones, Stephanie G., Lawton, Anna E., Tennant, Peter, Baker, Alison, Gordon, Catherine, Blundell, Richard, Varathalingam, Anusha, Davies, Lee A., Schmid, Ralph A., Cheng, Seng H., Porteous, David J., Gill, Deborah R., Hyde, Stephen C.

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Limitations of the murine nose in the development of nonviral airway gene transfer von Griesenbach, Uta, Sumner-Jones, Stephanie G, Holder, Emma, Munkonge, Felix M, Wodehouse, Theresa, Smith, Stephen N, Wasowicz, Marguerite Y, Pringle, Ian, Casamayor, Isabel, Chan, Mario, Coles, Rebecca, Cornish, Nikki, Dewar, Ann, Doherty, Ann, Farley, Raymond, Green, Anne-Marie, Jones, Bryony L, Larsen, Mia D B, Lawton, Anna E, Manvell, Michelle, Painter, Hazel, Singh, Charanjit, Somerton, Lucinda, Stevenson, Barbara, Varathalingam, Anusha, Siegel, Craig, Scheule, Ronald K, Cheng, Seng H, Davies, Jane C, Porteous, David J, Gill, Deborah R, Boyd, A Christopher, Hyde, Steve C, Alton, Eric W F W

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Adenovirus-mediated In Utero Expression of CFTR Does Not Improve Survival of CFTR Knockout Mice von Davies, Lee A, Varathalingam, Anusha, Painter, Hazel, Lawton, Anna E, Sumner-Jones, Stephanie G, Nunez-Alonso, Graciela A, Chan, Mario, Munkonge, Felix, Alton, Eric WFW, Hyde, Stephen C, Gill, Deborah R

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Bridging the know–do gap in African road safety through social work von Jones, Steven, Carlson, Catherine, Sumner-Jones, Frances, Musoni, Olive

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