Amino Acid Derived Enamides:  Synthesis and Aminopeptidase Activity von Cesati, Richard R, Dwyer, Greg, Jones, Reinaldo C, Hayes, Megan P, Yalamanchili, Padmaja, Casebier, David S

Volltext

Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases von Caldwell, Richard D, Qiu, Hui, Askew, Ben C, Bender, Andrew T, Brugger, Nadia, Camps, Montserrat, Dhanabal, Mohanraj, Dutt, Vikram, Eichhorn, Thomas, Gardberg, Anna S, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Healey, Brian, Hodous, Brian L, Huck, Bayard R, Johnson, Theresa L, Jones, Christopher, Jones, Reinaldo C, Mochalkin, Igor, Morandi, Federica, Nguyen, Ngan, Meyring, Michael, Potnick, Justin R, Santos, Dusica Cvetinovic, Schmidt, Ralf, Sherer, Brian, Shutes, Adam, Urbahns, Klaus, Follis, Ariele Viacava, Wegener, Ansgar A, Zimmerli, Simone C, Liu-Bujalski, Lesley

Volltext

Discovery of quinazoline HPK1 inhibitors with high cellular potency von Toure, Momar, Johnson, Theresa, Li, Bin, Schmidt, Ralf, Ma, Hong, Neagu, Constantin, Lopez, Andrea Unzue, Wang, Yanping, Guler, Satenig, Xiao, YuFang, Henkes, Renate, Ho, Kevin, Zhang, Susan, Chu, Chia Lin, Gundra, Uma Mahesh, Porichis, Filippos, Li, Long, Maurer, Christine Katharina, Fang, Zhizhou, Musil, Djordje, DiPoto, Maria, Friis, Emily, Jones, Reinaldo, Jones, Christopher, Cummings, James, Chekler, Eugene, Tanzer, Eva Maria, Huck, Bayard, Sherer, Brian

Volltext

Photoredox C sp 3 −C sp 2 Reductive Cross‐Couplings of Cereblon Ligands for PROTAC Linker Exploration in Batch and Flow von Steiner, Alexander, Krieger, Johannes, Jones, Reinaldo, Böse, Dietrich, Wang, Yanping, Eggenweiler, Hans‐Michael, Williams, Jason D., Kappe, C. Oliver

Volltext

Photoredox Csp3−Csp2 Reductive Cross‐Couplings of Cereblon Ligands for PROTAC Linker Exploration in Batch and Flow von Steiner, Alexander, Krieger, Johannes, Jones, Reinaldo, Böse, Dietrich, Wang, Yanping, Eggenweiler, Hans‐Michael, Williams, Jason D., Kappe, C. Oliver

Volltext

Discovery of potent and selective reversible Bruton’s tyrosine kinase inhibitors von Qiu, Hui, Ali, Zahid, Bender, Andrew, Caldwell, Richard, Chen, Yi-Ying, Fang, Zhizhou, Gardberg, Anna, Glaser, Nina, Goettsche, Anja, Goutopoulos, Andreas, Grenningloh, Roland, Hanschke, Bettina, Head, Jared, Johnson, Theresa, Jones, Christopher, Jones, Reinaldo, Kulkarni, Shashank, Maurer, Christine, Morandi, Federica, Neagu, Constantin, Poetzsch, Sven, Potnick, Justin, Schmidt, Ralf, Roe, Katherine, Viacava Follis, Ariele, Wing, Carolyn, Zhu, Xiaohua, Sherer, Brian

Volltext

Discovery of potent and selective reversible Bruton?s tyrosine kinase inhibitors von Qiu, Hui, Ali, Zahid, Bender, Andrew, Caldwell, Richard, Chen, Yi-Ying, Fang, Zhizhou, Gardberg, Anna, Glaser, Nina, Goettsche, Anja, Goutopoulos, Andreas, Grenningloh, Roland, Hanschke, Bettina, Head, Jared, Johnson, Theresa, Jones, Christopher, Jones, Reinaldo, Kulkarni, Shashank, Maurer, Christine, Morandi, Federica, Neagu, Constantin, Poetzsch, Sven, Potnick, Justin, Schmidt, Ralf, Roe, Katherine, Follis, Ariele Viacava, Wing, Carolyn, Zhu, Xiaohua, Sherer, Brian

Volltext

Identification of Clinical Candidate M2698, a Dual p70S6K and Akt Inhibitor, for Treatment of PAM Pathway-Altered Cancers von DeSelm, Lizbeth, Huck, Bayard, Lan, Ruoxi, Neagu, Constantin, Potnick, Justin, Xiao, Yufang, Chen, Xiaoling, Jones, Reinaldo, Richardson, Thomas E, Heasley, Brian H, Haxell, Thomas, Moore, Joseph, Tian, Hui, Georgi, Katrin, Rohdich, Felix, Sutton, Amanda, Johnson, Theresa, Mochalkin, Igor, Jackson, Jennifer, Lin, Jing, Crowley, Lindsey, Machl, Andreas, Clark, Anderson, Wilker, Erik, Sherer, Brian, Goutopoulos, Andreas

Volltext

Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit von Qiu, Hui, Liu-Bujalski, Lesley, Caldwell, Richard D, Follis, Ariele Viacava, Gardberg, Anna, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Johnson, Theresa, Jones, Reinaldo, Mochalkin, Igor, Morandi, Federica, Neagu, Constantin, Sherer, Brian

Volltext

Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitors von Qiu, Hui, Liu-Bujalski, Lesley, Caldwell, Richard D., Viacava Follis, Ariele, Gardberg, Anna, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Johnson, Theresa, Jones, Christopher C.V., Jones, Reinaldo, Mochalkin, Igor, Morandi, Federica, Neagu, Constantin, Potnick, Justin, Sherer, Brian

Volltext

Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk von Caldwell, Richard, Liu-Bujalski, Lesley, Qiu, Hui, Mochalkin, Igor, Jones, Reinaldo, Neagu, Constantin, Goutopoulos, Andreas, Grenningloh, Roland, Johnson, Theresa, Sherer, Brian, Gardberg, Anna, Follis, Ariele Viacava, Morandi, Federica, Head, Jared

Volltext

Discovery of Affinity‐Based Probes for Btk Occupancy Assays von Qiu, Hui, Caldwell, Richard, Liu‐Bujalski, Lesley, Goutopoulos, Andreas, Jones, Reinaldo, Potnick, Justin, Sherer, Brian, Bender, Andrew, Grenningloh, Roland, Xu, Daigen, Gardberg, Anna, Mochalkin, Igor, Johnson, Theresa, Viacava Follis, Ariele, Head, Jared, Morandi, Federica

Volltext

PYRIMIDINE PYRAZOLYL DERIVATIVES AND THEIR USE AS IRAK INHIBITORS von JONES, REINALDO, JORAND-LEBRUN, CATHERINE

Volltext bestellen

Pyrimidine pyrazolyl derivatives and their use as IRAK inhibitors von JONES, Reinaldo, JORAND-LEBRUN, Catherine

Volltext bestellen

Pyrimidine pyrazolyl derivatives and pharmaceutical compositions containing them von JORAND-LEBRUN Catherine, JONES Reinaldo

Volltext bestellen

Synthesis and Cardiac Imaging of 18F-Ligands Selective for β1-Adrenoreceptors von Radeke, Heike S, Purohit, Ajay, Harris, Thomas D, Hanson, Kelley, Jones, Reinaldo, Hu, Carol, Yalamanchili, Padmaja, Hayes, Megan, Yu, Ming, Guaraldi, Mary, Kagan, Mikhail, Azure, Michael, Cdebaca, Michael, Robinson, Simon, Casebier, David

Volltext

Synthesis and Cardiac Imaging of (18)F-Ligands Selective for β1-Adrenoreceptors von Radeke, Heike S, Purohit, Ajay, Harris, Thomas D, Hanson, Kelley, Jones, Reinaldo, Hu, Carol, Yalamanchili, Padmaja, Hayes, Megan, Yu, Ming, Guaraldi, Mary, Kagan, Mikhail, Azure, Michael, Cdebaca, Michael, Robinson, Simon, Casebier, David

Volltext

Synthesis and Cardiac Imaging of 18 F-Ligands Selective for β 1 -Adrenoreceptors von Radeke, Heike S., Purohit, Ajay, Harris, Thomas D., Hanson, Kelley, Jones, Reinaldo, Hu, Carol, Yalamanchili, Padmaja, Hayes, Megan, Yu, Ming, Guaraldi, Mary, Kagan, Mikhail, Azure, Michael, Cdebaca, Michael, Robinson, Simon, Casebier, David

Volltext

Substituted pyrazoles as IRAK inhibitors von Jones, Reinaldo, Jorand-Lebrun, Catherine

Volltext bestellen

Pyrimidine pyrazolyl derivatives and their use as IRAK inhibitors von JONES, Reinaldo, JORAND-LEBRUN, Catherine

Volltext bestellen