Quantitative accuracy of positron emission tomography/magnetic resonance and positron emission tomography/computed tomography for cervical cancer von Oldan, Jorge Daniel, Khandani, Amir Hossein, Fielding, Julia R., Jones, Ellen Louise, Gehrig, Paola Alvarez, Sills, Tiffany, Roy, Pinakpani, Lin, Weili

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Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study von Copson, Ellen R, Maishman, Tom C, Tapper, Will J, Cutress, Ramsey I, Greville-Heygate, Stephanie, Altman, Douglas G, Eccles, Bryony, Gerty, Sue, Durcan, Lorraine T, Jones, Louise, Evans, D Gareth, Thompson, Alastair M, Pharoah, Paul, Easton, Douglas F, Dunning, Alison M, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J, Hamed, Hisham, Hodgson, Shirley, Simmonds, Peter, Stanton, Louise, Eccles, Diana M

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The 100 000 Genomes Project: bringing whole genome sequencing to the NHS von Turnbull, Clare, Scott, Richard H, Thomas, Ellen, Jones, Louise, Murugaesu, Nirupa, Pretty, Freya Boardman, Halai, Dina, Baple, Emma, Craig, Clare, Hamblin, Angela, Henderson, Shirley, Patch, Christine, O’Neill, Amanda, Devereaux, Andrew, Smith, Katherine, Martin, Antonio Rueda, Sosinsky, Alona, McDonagh, Ellen M, Sultana, Razvan, Mueller, Michael, Smedley, Damian, Toms, Adam, Dinh, Lisa, Fowler, Tom, Bale, Mark, Hubbard, Tim, Rendon, Augusto, Hill, Sue, Caulfield, Mark J

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Whole-genome sequencing reveals host factors underlying critical COVID-19 von Kousathanas, Athanasios, Pairo-Castineira, Erola, Rawlik, Konrad, Stuckey, Alex, Odhams, Christopher A., Walker, Susan, Russell, Clark D., Malinauskas, Tomas, Wu, Yang, Millar, Jonathan, Shen, Xia, Elliott, Katherine S., Griffiths, Fiona, Oosthuyzen, Wilna, Morrice, Kirstie, Keating, Sean, Wang, Bo, Rhodes, Daniel, Klaric, Lucija, Zechner, Marie, Parkinson, Nick, Siddiq, Afshan, Goddard, Peter, Donovan, Sally, Maslove, David, Nichol, Alistair, Semple, Malcolm G., Zainy, Tala, Maleady-Crowe, Fiona, Todd, Linda, Salehi, Shahla, Knight, Julian, Elgar, Greg, Chan, Georgia, Arumugam, Prabhu, Patch, Christine, Rendon, Augusto, Bentley, David, Kingsley, Clare, Kosmicki, Jack A., Horowitz, Julie E., Baras, Aris, Abecasis, Goncalo R., Ferreira, Manuel A. R., Justice, Anne, Mirshahi, Tooraj, Oetjens, Matthew, Rader, Daniel J., Ritchie, Marylyn D., Verma, Anurag, Fowler, Tom A., Shankar-Hari, Manu, Summers, Charlotte, Hinds, Charles, Horby, Peter, Ling, Lowell, McAuley, Danny, Montgomery, Hugh, Openshaw, Peter J. M., Elliott, Paul, Walsh, Timothy, Tenesa, Albert, Fawkes, Angie, Murphy, Lee, Rowan, Kathy, Ponting, Chris P., Vitart, Veronique, Wilson, James F., Yang, Jian, Bretherick, Andrew D., Scott, Richard H., Hendry, Sara Clohisey, Moutsianas, Loukas, Law, Andy, Caulfield, Mark J., Baillie, J. Kenneth

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Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial von Abdulakeem, Ajibode, Adams, Tim, Ahmad, Syed, Ali, Nayab, Allen, Kerry, Arora, Rishi, Bagmane, Dinesh, Baker, Rebecca, Bawa, Fareha, Bell, Pippa, Bhandal, Khushpreet, Browne, Bria, Brudlo, Wojciech, Cannons, Vivienne, Cathie, Katrina, Chappell, Lucy, Chiapparino, Angela, Chiu, Matthew, Chudgar, Dip, Crichton, Charles, Cummings-Fosong, Gillian, Cuthbertson, Rebecca, Davidson, Neil Davidson, Dean, Julie, Dearden, Effie, Donnachie, Joanne, Edwards, Kennedy, Farrell, Barbara, Flynn, Rachel, Garner, Zoe, Gerard, Peter, Glover, Kyle, Gould, Susan, Greenfield, Philippa, Griffiths, Sarah, Grounds, Jenny, Gurung, Bhawana, Haldeos, Anne, Harper, Heather, Hazelton, Tracy, Henry, Joanne, Hossain, Rashed, Hu, Ying, Ipe, Anil, Jones, Ben, Kallistrou, Efthymia, Kubisz-Pudelko, Agnieszka, Laha, Shondipon, Lang, Stephen, Lees, Jennifer, Matila, Darwin, McLaren, Andrew, Morgan, Patrick, Muazzam, Ali, Muglu, Javaid, Nandani, Aarti, Neal, Alan, O'Kane, Mark, Okpala, Iheoma, O'Neill, Connaire, Osman, Wa'el, Oxlade, Ruth, Parambil, Vinay, Patel, Naleem, Pavord, Susan, Potoczna, Dorota, Pristopan, Veronika, Rahimi, Haseena R, Ramali, Mohamed, Ratcliff, Simbisai, Reynolds, Piero, Riley, Hannah, Roberts, Jean, Rogers, Joanne, Rosaroso, Lace P, Rughani, Prita, Salberg, Armorel, Samyraju, Manjula, Sands, Sarah, Saunderson, Anne, Singizi, Bryan, Sloan, Derek, Smallshaw, Karen D, Snell, David, Spencer, Branwell, Spencer, Sue, Sultan, Sugrah, Summerton, Mark, Swift, Pauline, Taylor, Leanne, Tyler, Jayne, Velusamy, Anitha, Watkins, Lynn, Weller, Samantha, Williams, Ava, Williams, Jennie, Williams, Matthew, Woollen, Louisa, Yearwood Martin, Charlotte, Zaher, Su

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SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses von Wang, Beibei, Skelly, Donal, Pan, Daniel, Omo-Dare, Nicola, Koeckerling, David, Jenkin, Daniel, Fernandes da Costa, Cristiano, Malik, Tariq, Baillie, J. Kenneth, Klenerman, Paul, Pollard, Andrew J., Conlon, Christopher, Jeffery, Katie, Stafford, Lizzie, Chand, Meera, Green, Christoper A., Harrison, Ewen M., Wai Ho, Antonia Ying, Palmarini, Massimo, Price, Nicholas, Robertson, David L., Sigfrid, Louise, Sriskandan, Shiranee, Stuart, David, Swann, Olivia V., Tedder, Richard S., Turtle, Lance CW, Zambon, Maria, Pius, Riinu, Knight, Stephen R., Harrison, Janet, Jackson, Clare, Gamble, Carrol, Plotkin, Daniel, Lee, James, Wham, Murray, Shaw, Victoria, McDonald, Sarah E., Armstrong, Jane A., Ashworth, Milton, Barlow, Samantha L., Bullock, Katie, Davis, Christopher, Dunn, Chris, King, Katharine, Kiy, Robyn T., Lant, Suzannah, Latawiec, Diane, Mancini, Maria, Metelmann, Soeren, Penrice-Randal, Rebekah, Pilgrim, Jack, van Tonder, Libby, Murphy, Lee, Morrice, Kirstie, Gilchrist, Tammy, Aldera, Erin L., Barnass, Stella, Bernatoniene, Jolanta, Bothma, Pieter, Brittain-Long, Robin, Caruth, Vikki, Collini, Paul, Dawson, Chris, Dervisevic, Samir, Dushianthan, Ahilanadan, Evans, Cariad, Harvey, Daniel, Hawcutt, Daniel B., Hodgson, Luke, Hormis, Anil, Kerrison, Caroline, Larkin, Susan, Little, Jeff, Meda, Manjula, Moon, James, Mortimore, Katherine, Murphy, Michael, O’Shea, Matthew K., Otahal, Igor, Panchatsharam, Selva, Patel, Brij, Pepperell, Justin, Peters, Mark, Price, David, Reschreiter, Henrik, Ruge, Bobby, Saluja, Taranprit, Sizer, Jeremy, Shankar-Hari, Manu, Snelson, Catherine, Staines, Nikki, Twagira, Mary, Vincent-Smith, Lisa, Visuvanathan, Shico, Welters, Ingeborg, Wolverson, Adam, Yates, Bryan, Fry, Elizabeth E., Ren, Jingshan

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Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation von Vietri, Marina, Schultz, Sebastian W., Bellanger, Aurélie, Jones, Carl M., Petersen, Louise I., Raiborg, Camilla, Skarpen, Ellen, Pedurupillay, Christeen Ramane J., Kjos, Ingrid, Kip, Eline, Timmer, Romy, Jain, Ashish, Collas, Philippe, Knorr, Roland L., Grellscheid, Sushma N., Kusumaatmaja, Halim, Brech, Andreas, Micci, Francesca, Stenmark, Harald, Campsteijn, Coen

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Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial von Peters, Mark J, Gould, Doug W, Ray, Samiran, Thomas, Karen, Chang, Irene, Orzol, Marzena, O'Neill, Lauran, Agbeko, Rachel, Au, Carly, Draper, Elizabeth, Elliot-Major, Lee, Giallongo, Elisa, Jones, Gareth A L, Lampro, Lamprini, Lillie, Jon, Pappachan, Jon, Peters, Sam, Ramnarayan, Padmanabhan, Sadique, Zia, Rowan, Kathryn M, Harrison, David A, Mouncey, Paul R

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SARS-CoV-2 infection in acute pancreatitis increases disease severity and 30-day mortality: COVID PAN collaborative study von Leeds, John S, Oppong, Kofi, Kanwar, Aditya, Marzouk, Ahmed, Belgaumkar, Ajay, Gupta, Ajay, Awan, Altaf, Balakrishnan, Anita, Caruana, Clifford, Borg, Cynthia-Michelle, Gomez, Dhanny, Damaskos, Dimitrios, Finch, Guy, Ebied, Husam, R A Skipworth, James, Milburn, James, Latif, Javed, Windsor, John A, Wang, Kelvin, Ravi, Krish, V Coats, Maria, Hollyman, Marianne, Phillips, Mary, Okocha, Michael, Kumar, Nagappan, Shah, Nehal, Magee, Connor, Al-Sarireh, Bilal, Benhmida, Rami, Singhal, Rishi, Balachandra, Srinivasan, Jaunoo, Shameen, Dwerryhouse, Simon, Boyce, Tamsin, Charalampakis, Vasileios, Kanakala, Venkat, Nayar, Manu, Madhavan, Anantha, Mingoli, Andrea, Cotton, Arthur, Famokunwa, Bamidele, Cirillo, Bruno, Jordan, Caitlin, DermotStewart, Charles Geoffrey, Marshall, Daniel, Bourne, David, Chandla, Danny, Yeşilyurt, Değercan, Rutherford, Duncan, Murgitroyd, Ellen, Tokidis, Evripidis, Soliman, Faris, Singh, Gautam, Brachini, Gioia, Sen, Gourab, Khan, Shabuddin, Said, Hadil, Whewell, Harriet, Spiers, Harry VM, De’Ath, Henry D, Bhatti, Imran, Sert, İsmail, Martin, Jack, Blackwell, James, Williams, James, Moore, Jasmine Grace, Wheat, Jennifer, Fenech, Jeremy, French, Jeremy, Scott, John, Hartshorn, Kai, McGivern, Kieran, Brown, Leo Richard, Finch, Louise M, Kaur, Mandeep, Quinn, Marcus, Jama, Marwa Ahmed, Lahiri, Rajiv, Hopkins, James, abousamra, Mohamed, Hammoda, Mohammed, Qadeer, Muhammad Ali, Zafar, Muneeb, Chidumije, Nnaemeka, Tiwari, Navneet, Spence, Olivia, Ghaneh, Paula, Strong, Paula, Szatmary, Peter, Muhammad, Qazi R, Sutton, Robert, Young, Robert, Taylor, Roland, Allen, Sophie, Goh, Stephanie, Brown, Steven, Cowie, Stuart, Robinson, Stuart, Kaya, Tayfun, Morrison-Jones, Victoria

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Widespread genomic influences on phenotype in Dravet syndrome, a ‘monogenic’ condition von Martins Custodio, Helena, Clayton, Lisa M, Bellampalli, Ravishankara, Pagni, Susanna, Silvennoinen, Katri, Caswell, Richard, Brunklaus, Andreas, Guerrini, Renzo, Koeleman, Bobby P C, Lemke, Johannes R, Møller, Rikke S, Scheffer, Ingrid E, Weckhuysen, Sarah, Zara, Federico, Zuberi, Sameer, Kuchenbaecker, Karoline, Balestrini, Simona, Mills, James D, Sisodiya, Sanjay M

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Markers of β-Cell Failure Predict Poor Glycemic Response to GLP-1 Receptor Agonist Therapy in Type 2 Diabetes von Jones, Angus G, McDonald, Timothy J, Shields, Beverley M, Hill, Anita V, Hyde, Christopher J, Knight, Bridget A, Hattersley, Andrew T

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Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma von Jones, Christine L., Degasperi, Andrea, Grandi, Vieri, Amarante, Tauanne D., Mitchell, Tracey J., Nik-Zainal, Serena, Whittaker, Sean J.

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Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial von Abdulakeem, Ajibode, Acosta, Andres, Aziz, N, Badhan, Gurpreet R, Banerjee, Ritwik, Baral, Ananya M, Bawa, Fareha, Bennett, Lorraine, Beresford, Matthew, Brearey, Stephen, Cabandugama, Amanda, Cannons, Vivienne, Carter, Jonathan, Chin, KokWai, Clark, James, Clark, Kaylea, Clarke, Roseanne, Colley, Julie, Crichton, Charles, Currie, Craig, Duric, Natalie, Farrell, Barbara, Fenton, Melisa, Flanagan, Michael, Flynn, Rachel, Fung, Carrie, Garner, Lucie, Gedge, Ian, Gibson, Bethan, Gogoi, Sukanya, Goyal, Sunil, Grieg, Natasha, Gunganah, Kirun, Gureviciute, Alvyda, Harvala, Heli, Hazenberg, Phoebe, Hector, Gemma, Heys, Joseph, Holmes, Rebecca, Ingle, Tejas, Iqbal Sait, Faisal, Jenkin, Ifan, Johnstone, Dawn, Kapil, Vikas, Kingsmore, Laura, Lason, Wojciech, Latham, Victoria, Lee, Shi Han, Lees, Diana, Llewelyn, Martin, Lloyd, Aaron, Looby, Laura, Luke, H, Madziva, Lorraine, Mallinder, Petrina, Martin, Winston, Masood, Mohammad T, McKenna, Shirley, McNelis, Una, Medveczky, Thomas, Metherell, Stella, Mihalca-Mason, Loredana, Moyo, Quberkani, Nair, Rajiv, Nethercott, Daniel, Noori, Zaid, Osanlou, Rostam, Parfitt, Louise, Peirce, Benjamin H, Pereira, Rita, Plumptre, Charles, Potter, Jean, Ratcliff, Simbisai, Rehman, Zainab, Rizvi, Syed AS, Roberts, Nicky, Rowley, Megan, Sanderson, Amy, Sellick, Victoria, Shortman, Rob, Smith, Chris, Smith, Sally, Stratton, Emma, Stuttard, Matt, Tamblin-Hopper, Phoebe, Taylor, Margaret, Thomas, Caradog, Umeadi, Judith, Veli, Neyme, Vernon, Britney, Wakefield, Alice, Weinreich, David M, West, Ruth, Wignall, Christopher, Wills, Louise, Winder, Piers, Winslow, Helen, Worley, Daniel, Ylquimiche, Laura, Yu, Chrissie

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Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial von Chappell, Lucy C, Bell, Jennifer L, Smith, Anne, Linsell, Louise, Juszczak, Edmund, Dixon, Peter H, Chambers, Jenny, Hunter, Rachael, Dorling, Jon, Williamson, Catherine, Thornton, Jim G, Ahmed, Irshad, Arya, Rita, Beckett, Virginia, Bhide, Amarnath, Brown, Heather, Bugg, George, Cameron, Helen, Deole, Nishigandh, Dey, Madhuchanda, Dwyer, James, Fahel, Leila, Gada, Ruta, Girling, Joanna, Haestier, Anna, Hughes, Sean, Indusekhar, Radha, Jones, Bryony, Khan, Rahila, Kirkpatrick, Alison, Knox, Ellen, Lincoln, Karen, MacDougall, Malcolm, Majoko, Franz, McIntyre, Karen, Noori, Muna, Oakley, Wendy, Preston, Jane, Ranka, Poornima, Rashid, Mumtaz, Salloum, Marwan, Samyraju, Manjula, Schram, Catharina, Sen, Seema, Stone, Sophia, Tan, Bee

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Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial von Abdulakeem, Ajibode, Acosta, Andres, Ahmad, Syed, Ali, Nayab, Allen, Kerry, Anand, Atul, Anim-Somuah, Millicent, Anstey, Patrick James, Ayaz, Eman, Aziz, Ghazala, Bell, Pippa, Bergstrom, Malin, Bhandal, Khushpreet, Bowker, Philip, Brodsky, Mary, Bromley, David, Bukhari, Marwan, Carey, Rachel, Cendl, Hankins, Chaudhry, Iram, Chiapparino, Angela, Chiu, Matthew, Choudhary, Vandana, Chowdhury, Mahibbur, Church, Elaine, Dean, Tessa, Drake, Chelsea, Drysdale, Simon, Elder, Jennifer, El-Din, Mohammed, Elgamal, Mayy Magdy, Farrell, Barbara, Field, Ben, Flanagan, Michael, Fox, Olivia, Galloway, James, Gelmon, L, Ghosh, Sudhamay, Gibson, Sian, Grieve, Douglas, Hackney, Pamela, Hill, Phoebe, Howard-Griffin, Richard, Huyen, Thuong, Iqbal, Mohammed, Janmohamed, Azara, Jansz, Sabrina, Jegede, Debbie, Jenkin, Ifan, Jetha, Champa, Jones, James, Jones, Jonathon, Josiah, Benz, Kathirgamachelvam, Janarth, King, Sarah, Knapp, Christopher P, Lamparski, Michal, Lang, Alidih, Lloyd, Aimee, MacNair, Andrew, Mapfunde, Isheunesu T, Marshall, Riley, Masud, Aaqib, Matonhodze, Max, McCarthy, Michelle, McCullagh, Iain James, McGregor, Annemarie, Min, Zayar, Mtuwa, Sheila, Murray, Lorna, Mutema, Eric, Myers, Alice, O'Connell, Lorcan, Perumpral, Thomas M, Price, Claire, Rundell, Sharon, Singh, Claire, Sivakumran, Darsh, Skorupinska, Iwona, Smit, Carien, Smith, Christopher, Sturdy, Ann, Sturney, Sharon, Sultan, Sugrah, Tewari, Shirish, Tovey, Peter, Tozer, Richard, Venables, Ian, Wallen, Jessica, Warwick, Gill, Waugh, Victoria, Welch, James, Westwood, Alice, White, James, Wickens, Olivia, Wong, Sam, Wood, Louise, Wooldridge, Gemma, Wootton, Joanne, Young, Louise

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The Link between Regional Tidal Stretch and Lung Injury during Mechanical Ventilation von Yen, Seiha, Preissner, Melissa, Bennett, Ellen, Dubsky, Stephen, Carnibella, Richard, O'Toole, Ronan, Roddam, Louise, Jones, Heather, Dargaville, Peter A, Fouras, Andreas, Zosky, Graeme R

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Obesity and the outcome of young breast cancer patients in the UK: the POSH study von Copson, E.R., Cutress, R.I., Maishman, T., Eccles, B.K., Gerty, S., Stanton, L., Altman, D.G., Durcan, L., Wong, C., Simmonds, P.D., Jones, L., Eccles, D.M.

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Prospective Observational Study of Breast Cancer Treatment Outcomes for UK Women Aged 18―40 Years at Diagnosis: The POSH Study von COPSON, Ellen, ECCLES, Bryony, JONES, Louise, BLISS, Judith, ECCLES, Diana, MAISHMAN, Tom, GERTY, Sue, STANTON, Louise, CUTRESS, Ramsey I, ALTMAN, Douglas G, DURCAN, Lorraine, SIMMONDS, Peter, LAWRENCE, Gill

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Recommendations for the predictive genetic test in Huntington's disease von MacLeod, R, Tibben, A, Frontali, M, Evers-Kiebooms, G, Jones, A, Martinez-Descales, A, Roos, RA

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Reference Intervals for Brachial Artery Flow-Mediated Dilation and the Relation With Cardiovascular Risk Factors von Holder, Sophie M., Bruno, Rosa Maria, Shkredova, Daria A., Dawson, Ellen A., Jones, Helen, Hopkins, Nicola D., Hopman, Maria T.E., Bailey, Tom G., Coombes, Jeff S., Askew, Christopher D., Naylor, Louise, Maiorana, Andrew, Ghiadoni, Lorenzo, Thompson, Andrew, Green, Daniel J., Thijssen, Dick H.J.

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