Leveraging Systematic Functional Analysis to Benchmark an In Silico Framework Distinguishes Driver from Passenger MEK Mutants in Cancer von Hanrahan, Aphrothiti J, Sylvester, Brooke E, Chang, Matthew T, Elzein, Arijh, Gao, Jianjiong, Han, Weiwei, Liu, Ye, Xu, Dong, Gao, Sizhi P, Gorelick, Alexander N, Jones, Alexis M, Kiliti, Amber J, Nissan, Moriah H, Nimura, Clare A, Poteshman, Abigail N, Yao, Zhan, Gao, Yijun, Hu, Wenhuo, Wise, Hannah C, Gavrila, Elena I, Shoushtari, Alexander N, Tiwari, Shakuntala, Viale, Agnes, Abdel-Wahab, Omar, Merghoub, Taha, Berger, Michael F, Rosen, Neal, Taylor, Barry S, Solit, David B

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Anti-PD-1/L1 lead-in before MAPK inhibitor combination maximizes antitumor immunity and efficacy von Wang, Yujue, Liu, Sixue, Yang, Zhentao, Algazi, Alain P., Lomeli, Shirley H., Wang, Yan, Othus, Megan, Hong, Aayoung, Wang, Xiaoyan, Randolph, Chris E., Jones, Alexis M., Bosenberg, Marcus W., Byrum, Stephanie D., Tackett, Alan J., Lopez, Henry, Yates, Clayton, Solit, David B., Ribas, Antoni, Piva, Marco, Moriceau, Gatien, Lo, Roger S.

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Loss of NF1 in Cutaneous Melanoma Is Associated with RAS Activation and MEK Dependence von NISSAN, Moriah H, PRATILAS, Christine A, MERGHOUB, Taha, RIBAS, Antoni, CHAPMAN, Paul B, YAEGER, Rona, TAYLOR, Barry S, SCHULTZ, Nikolaus, BERGER, Michael F, ROSEN, Neal, SOLIT, David B, JONES, Alexis M, RAMIREZ, Ricardo, WON, Helen, CAILIAN LIU, TIWARI, Shakuntala, LI KONG, HANRAHAN, Aphrothiti J, ZHAN YAO

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The Association Between Density of Alcohol Establishments and Violent Crime Within Urban Neighborhoods von Toomey, Traci L., Erickson, Darin J., Carlin, Bradley P., Lenk, Kathleen M., Quick, Harrison S., Jones, Alexis M., Harwood, Eileen M.

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Reversal by RARα agonist Am580 of c-Myc-induced imbalance in RARα/RARγ expression during MMTV-Myc tumorigenesis von Bosch, Almudena, Bertran, Silvina P, Lu, Yongke, Garcia, Avalon, Jones, Alexis M, Dawson, Marcia I, Farias, Eduardo F

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Abstract 2: Vertical MAPK pathway targeting in novel genetically engineered mouse and cell line models of NF1-altered melanoma: the mSK-Mel murine cohort von Jones, Alexis M., Hanrahan, Aphrothiti J., Nissan, Moriah H., Monette, Sebastien, Chen, Ziyu, Hu, Wenhuo, Misale, Sandra, Schulze, Isabell, Vasani, Naresh, Liu, Cailian, Yang, Xia, Abu-Akeel, Mohsen, de Stanchina, Elisa, Schultz, Nikolaus, Berger, Michael F., Rosen, Neal, Merghoub, Taha, Solit, David B.

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Reversal by RAR[alpha] agonist Am580 of c-Myc-induced imbalance in RAR[alpha]/RAR[gamma] expression during MMTV-Myc tumorigenesis von Bosch, Almudena, Bertran, Silvina P, Lu, Yongke, Garcia, Avalon, Jones, Alexis M, Dawson, Marcia I, Farias, Eduardo F

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Glove von Jones Phil A, Jones Alexis M

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Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation von Mahajan, Kiran, Coppola, Domenico, Challa, Sridevi, Fang, Bin, Chen, Y Ann, Zhu, Weiwei, Lopez, Alexis S, Koomen, John, Engelman, Robert W, Rivera, Charlene, Muraoka-Cook, Rebecca S, Cheng, Jin Q, Schönbrunn, Ernst, Sebti, Said M, Earp, H Shelton, Mahajan, Nupam P

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Thiazolothiazole Fluorophores Exhibiting Strong Fluorescence and Viologen-Like Reversible Electrochromism von Woodward, Alexis N, Kolesar, Justin M, Hall, Sara R, Saleh, Nemah-Allah, Jones, Daniel S, Walter, Michael G

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Seasonal and spatial dynamics of enteric viruses in wastewater and in riverine and estuarine receiving waters von Farkas, Kata, Cooper, David M., McDonald, James E., Malham, Shelagh K., de Rougemont, Alexis, Jones, Davey L.

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Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging von Powell, Domonica N., Swimm, Alyson, Sonowal, Robert, Bretin, Alexis, Gewirtz, Andrew T., Jones, Rheinallt M., Kalman, Daniel

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Major impacts of climate change on deep-sea benthic ecosystems von Sweetman, Andrew K., Thurber, Andrew R., Smith, Craig R., Levin, Lisa A., Mora, Camilo, Wei, Chih-Lin, Gooday, Andrew J., Jones, Daniel O. B., Rex, Michael, Yasuhara, Moriaki, Ingels, Jeroen, Ruhl, Henry A., Frieder, Christina A., Danovaro, Roberto, Würzberg, Laura, Baco, Amy, Grupe, Benjamin M., Pasulka, Alexis, Meyer, Kirstin S., Dunlop, Katherine M., Henry, Lea-Anne, Roberts, J. Murray

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Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes von Rahim, Maha K., Okholm, Trine Line H., Jones, Kyle B., McCarthy, Elizabeth E., Liu, Candace C., Yee, Jacqueline L., Tamaki, Stanley J., Marquez, Diana M., Tenvooren, Iliana, Wai, Katherine, Cheung, Alexander, Davidson, Brittany R., Johri, Vrinda, Samad, Bushra, O’Gorman, William E., Krummel, Matthew F., van Zante, Annemieke, Combes, Alexis J., Angelo, Michael, Fong, Lawrence, Algazi, Alain P., Ha, Patrick, Spitzer, Matthew H.

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Global absence and targeting of protective immune states in severe COVID-19 von Combes, Alexis J., Courau, Tristan, Kuhn, Nicholas F., Hu, Kenneth H., Ray, Arja, Chen, William S., Chew, Nayvin W., Cleary, Simon J., Kushnoor, Divyashree, Reeder, Gabriella C., Shen, Alan, Tsui, Jessica, Hiam-Galvez, Kamir J., Muñoz-Sandoval, Priscila, Zhu, Wandi S., Lee, David S., Sun, Yang, You, Ran, Magnen, Mélia, Rodriguez, Lauren, Im, K. W., Serwas, Nina K., Leligdowicz, Aleksandra, Zamecnik, Colin R., Loudermilk, Rita P., Wilson, Michael R., Ye, Chun J., Fragiadakis, Gabriela K., Looney, Mark R., Chan, Vincent, Ward, Alyssa, Carrillo, Sidney, Matthay, Michael, Erle, David J., Woodruff, Prescott G., Langelier, Charles, Kangelaris, Kirsten, Hendrickson, Carolyn M., Calfee, Carolyn, Rao, Arjun Arkal, Krummel, Matthew F.

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Inequities in Diabetic Ketoacidosis Among Patients With Type 1 Diabetes and COVID-19: Data From 52 US Clinical Centers von Ebekozien, Osagie, Agarwal, Shivani, Noor, Nudrat, Albanese-O’Neill, Anastasia, Wong, Jenise C, Seeherunvong, Tossaporn, Sanchez, Janine, DeSalvo, Daniel, Lyons, Sarah K, Majidi, Shideh, Wood, Jamie R, Acharya, Runa, Aleppo, Grazia, Sumpter, Kathryn M, Cymbaluk, Anna, Shah, Nirali A, Van Name, Michelle, Cruz-Aviles, Lisa, Alonso, Guy Todd, Gallagher, Mary Pat, Sanda, Srinath, Feuer, Alexis Jamie, Cossen, Kristina, Rioles, Nicole, Jones, Nana-Hawa Yayah, Kamboj, Manmohan K, Hirsch, Irl B

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An Anterior Cruciate Ligament Failure Mechanism von Chen, Junjie, Kim, Jinhee, Shao, Wenhao, Schlecht, Stephen H., Baek, So Young, Jones, Alexis K., Ahn, Taeyong, Ashton-Miller, James A., Banaszak Holl, Mark M., Wojtys, Edward M.

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Non-V600 BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer von Jones, Jeremy C, Renfro, Lindsay A, Al-Shamsi, Humaid O, Schrock, Alexa B, Rankin, Andrew, Zhang, Ben Y, Kasi, Pashtoon M, Voss, Jesse S, Leal, Alexis D, Sun, James, Ross, Jeffrey, Ali, Siraj M, Hubbard, Joleen M, Kipp, Benjamin R, McWilliams, Robert R, Kopetz, Scott, Wolff, Robert A, Grothey, Axel

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Engaging partners, lay persons, and learners through effective marketing and messaging von Johnson, 2nd, Theodore M, Freiji, Jason, Moore, Miranda A, Bender, Alexis A, Munroe, Dominique, Geresu, Hayat, Baxter, Grayson Gunn, Epps, Fayron, Taylor, Leslie F, Bussey-Jones, Jada, Sharp, Travis, Suggs, Andy

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Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies von Medina-Munoz, Hugo C., Kofman, Eric, Jagannatha, Pratibha, Boyle, Evan A., Yu, Tao, Jones, Krysten L., Mueller, Jasmine R., Lykins, Grace D., Doudna, Andrew T., Park, Samuel S., Blue, Steven M., Ranzau, Brodie L., Kohli, Rahul M., Komor, Alexis C., Yeo, Gene W.

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