Human Fatty Liver Disease: Old Questions and New Insights von Cohen, Jonathan C., Horton, Jay D., Hobbs, Helen H.

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Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis von BasuRay, Soumik, Wang, Yang, Smagris, Eriks, Cohen, Jonathan C., Hobbs, Helen H.

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PNPLA3, CGI‐58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice von Wang, Yang, Kory, Nora, BasuRay, Soumik, Cohen, Jonathan C, Hobbs, Helen H

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Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci von Stender, Stefan, Kozlitina, Julia, Nordestgaard, Børge G, Tybjærg-Hansen, Anne, Hobbs, Helen H, Cohen, Jonathan C

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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease von Cohen, Jonathan C, Hobbs, Helen H, Romeo, Stefano, Kozlitina, Julia, Xing, Chao, Pertsemlidis, Alexander, Cox, David, Pennacchio, Len A, Boerwinkle, Eric

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PCSK9: a convertase that coordinates LDL catabolism von Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.

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Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion von Wang, Yan, Gusarova, Viktoria, Banfi, Serena, Gromada, Jesper, Cohen, Jonathan C, Hobbs, Helen H

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Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis von Smagris, Eriks, BasuRay, Soumik, Li, John, Huang, Yongcheng, Lai, Ka‐man V., Gromada, Jesper, Cohen, Jonathan C., Hobbs, Helen H.

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Atypical angiopoietin-like protein that regulates ANGPTL3 von Quagliarini, Fabiana, Wang, Yan, Kozlitina, Julia, Grishin, Nick V, Hyde, Rhonda, Boerwinkle, Eric, Valenzuela, David M, Murphy, Andrew J, Cohen, Jonathan C, Hobbs, Helen H

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Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis von Wang, Yan, Quagliarini, Fabiana, Gusarova, Viktoria, Gromada, Jesper, Valenzuela, David M., Cohen, Jonathan C., Hobbs, Helen H.

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Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans von Romeo, Stefano, Yin, Wu, Kozlitina, Julia, Pennacchio, Len A, Boerwinkle, Eric, Hobbs, Helen H, Cohen, Jonathan C

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Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice von Cohen, Jonathan C, May, Dalit, Afzal, Veena, Gong, Elaine, Pennacchio, Len A, Zhu, Yiwen, Rubin, Edward M, Attanasio, Catia, Blow, Matthew J, Visel, Axel

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Crystal structure of the human sterol transporter ABCG5/ABCG8 von Lee, Jyh-Yeuan, Kinch, Lisa N., Borek, Dominika M., Wang, Jin, Wang, Junmei, Urbatsch, Ina L., Xie, Xiao-Song, Grishin, Nikolai V., Cohen, Jonathan C., Otwinowski, Zbyszek, Hobbs, Helen H., Rosenbaum, Daniel M.

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ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion von Gusarova, Viktoria, Alexa, Corey A., Na, Erqian, Stevis, Panayiotis E., Xin, Yurong, Bonner-Weir, Susan, Cohen, Jonathan C., Hobbs, Helen H., Murphy, Andrew J., Yancopoulos, George D., Gromada, Jesper

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Hepatic ANGPTL3 regulates adipose tissue energy homeostasis von Wang, Yan, McNutt, Markey C., Banfi, Serena, Levin, Michael G., Holland, William L., Gusarova, Viktoria, Gromada, Jesper, Cohen, Jonathan C., Hobbs, Helen H.

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A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis von He, Shaoqing, McPhaul, Christopher, Li, John Zhong, Garuti, Rita, Kinch, Lisa, Grishin, Nick V., Cohen, Jonathan C., Hobbs, Helen H.

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Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways von Mitsche, Matthew A, McDonald, Jeffrey G, Hobbs, Helen H, Cohen, Jonathan C

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Genetic and Metabolic Determinants of Plasma PCSK9 Levels von Lakoski, Susan G., Lagace, Thomas A., Cohen, Jonathan C., Horton, Jay D., Hobbs, Helen H.

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Relative roles of ABCG5/ABCG8 in liver and intestine[S] von Wang, Jin, Mitsche, Matthew A., Lütjohann, Dieter, Cohen, Jonathan C., Xie, Xiao-Song, Hobbs, Helen H.

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Increased thermogenesis by a noncanonical pathway in ANGPTL3/8-deficient mice von Banfi, Serena, Gusarova, Viktoria, Gromada, Jesper, Cohen, Jonathan C., Hobbs, Helen H.

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