Crystallographic Evidence for Preformed Dimers of Erythropoietin Receptor Before Ligand Activation von Livnah, Oded, Stura, Enrico A., Middleton, Steven A., Johnson, Dana L., Jolliffe, Linda K., Wilson, Ian A.

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Small Peptides as Potent Mimetics of the Protein Hormone Erythropoietin von Wrighton, Nicholas C., Farrell, Francis X., Chang, Ray, Kashyap, Arun K., Barbone, Francis P., Mulcahy, Linda S., Johnson, Dana L., Barrett, Ronald W., Jolliffe, Linda K., Dower, William J.

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Functional Mimicry of a Protein Hormone by a Peptide Agonist: The EPO Receptor Complex at 2.8 Å von Livnah, Oded, Stura, Enrico A., Johnson, Dana L., Middleton, Steven A., Mulcahy, Linda S., Wrighton, Nicholas C., Dower, William J., Jolliffe, Linda K., Wilson, Ian A.

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1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogues as Novel and Potent Anticancer Cyclin-Dependent Kinase Inhibitors:  Synthesis and Evaluation of Biological Activities von Lin, Ronghui, Connolly, Peter J, Huang, Shenlin, Wetter, Steven K, Lu, Yanhua, Murray, William V, Emanuel, Stuart L, Gruninger, Robert H, Fuentes-Pesquera, Angel R, Rugg, Catherine A, Middleton, Steven A, Jolliffe, Linda K

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The in vitro and in vivo effects of JNJ-7706621 : A dual inhibitor of cyclin-dependent kinases and aurora kinases von EMANUEL, Stuart, RUGG, Catherine A, JOLLIFFE, Linda, MIDDLETON, Steven A, GRUNINGER, Robert H, RONGHUI LIN, FUENTES-PESQUERA, Angel, CONNOLLY, Peter J, WETTER, Steven K, HOLLISTER, Beth, KRUGER, Walter W, NAPIER, Cheryl

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Synthesis and Identification of [1,3,5]Triazine-pyridine Biheteroaryl as a Novel Series of Potent Cyclin-Dependent Kinase Inhibitors von Kuo, Gee-Hong, DeAngelis, Alan, Emanuel, Stuart, Wang, Aihua, Zhang, Yan, Connolly, Peter J, Chen, Xin, Gruninger, Robert H, Rugg, Catherine, Fuentes-Pesquera, Angel, Middleton, Steven A, Jolliffe, Linda, Murray, William V

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Increased potency of an erythropoietin peptide mimetic through covalent dimerization von Wrighton, Nicholas C, Balasubramanian, Palaniappan, Barbone, Francis P, Kashyap, Arun K, Farrell, Francis X, Jolliffe, Linda K, Barrett, Ronald W, Dower, William J

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The structure, organization, activation and plasticity of the erythropoietin receptor von Wilson, Ian A, Jolliffe, Linda K

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Identification of a 13 Amino Acid Peptide Mimetic of Erythropoietin and Description of Amino Acids Critical for the Mimetic Activity of EMP1 von Johnson, Dana L, Farrell, Francis X, Barbone, Francis P, McMahon, Frank J, Tullai, Jennifer, Hoey, Kenway, Livnah, Oded, Wrighton, Nicholas C, Middleton, Steven A, Loughney, Deborah A, Stura, Enrico A, Dower, William J, Mulcahy, Linda S, Wilson, Ian A, Jolliffe, Linda K

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A Vascular Endothelial Growth Factor Receptor-2 Kinase Inhibitor Potentiates the Activity of the Conventional Chemotherapeutic Agents Paclitaxel and Doxorubicin in Tumor Xenograft... von Stuart Emanuel, Robert H. Gruninger, Angel Fuentes-Pesquera, Peter J. Connolly, Jennifer A. Seamon, Susan Hazel, Rose Tominovich, Beth Hollister, Cheryl Napier, Michael R. D'Andrea, Michael Reuman, Gilles Bignan, Robert Tuman, Dana Johnson, David Moffatt, Mark Batchelor, Anne Foley, James O'Connell, Rodger Allen, Martin Perry, Linda Jolliffe, Steven A. Middleton

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In Vitro Characterization of Five Humanized OKT3 Effector Function Variant Antibodies von Xu, Danlin, Alegre, Maria-Luisa, Varga, Sally S., Rothermel, Annette L., Collins, Alexander M., Pulito, Virginia L., Hanna, Lewis S., Dolan, Kevin P., Parren, Paul W.H.I., Bluestone, Jeffrey A., Jolliffe, Linda K., Zivin, Robert A.

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3-Acyl-2,6-diaminopyridines as cyclin-dependent kinase inhibitors: synthesis and biological evaluation von Lin, Ronghui, Lu, Yanhua, Wetter, Steven K., Connolly, Peter J., Turchi, Ignatius J., Murray, William V., Emanuel, Stuart L., Gruninger, Robert H., Fuentes-Pesquera, Angel R., Adams, Mary, Pandey, Niranjan, Moreno-Mazza, Sandra, Middleton, Steven A., Jolliffe, Linda K.

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An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation von Jolliffe, Linda K, Wilson, Ian A, Livnah, Oded, Johnson, Dana L, Stura, Enrico A, Farrell, Francis X, Barbone, Francis P, You, Yun, Liu, Kathleen D, Goldsmith, Mark A, He, Wen, Krause, Christopher D, Pestka, Sidney

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A non-activating humanized anti-CD3 monoclonal antibody retains immunosuppressive properties in vivo von ALEGRE, M.-L, PETERSON, L. J, DANLIN XU, SATTAR, H. A, JEYARAJAH, D. R, KOWALKOWSKI, K, THISTLETHWAITE, J. R, ZIVIN, R. A, JOLLIFFE, L, BLUESTONE, J. A

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Arylpiperazine substituted heterocycles as Selective α1a adrenergic antagonists von Khatuya, Haripada, Hutchings, Richard H, Kuo, Gee-Hong, Pulito, Virginia L, Jolliffe, Linda K, Li, Xiaobing, Murray, William V

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Erythropoietin induces changes in gene expression in PC-12 cells von Renzi, Michael J, Farrell, Francis X, Bittner, Anton, Galindo, Jose E, Morton, Mike, Trinh, Heather, Jolliffe, Linda K

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Novel thiophene derivatives for the treatment of benign prostatic hyperplasia von Khatuya, Haripada, Pulito, Virginia L., Jolliffe, Linda K., Li, Xiaobing, Murray, William V.

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Shared and Unique Determinants of the Erythropoietin (EPO) Receptor Are Important for Binding EPO and EPO Mimetic Peptide von Middleton, Steven A., Barbone, Francis P., Johnson, Dana L., Thurmond, Robin L., You, Yun, McMahon, Frank J., Jin, Renzhe, Livnah, Oded, Tullai, Jennifer, Farrell, Francis X., Goldsmith, Mark A., Wilson, Ian A., Jolliffe, Linda K.

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Synthesis and erythropoietin receptor binding affinities of N,N-disubstituted amino acids von Connolly, Peter J, Wetter, Steven K, Murray, William V, Johnson, Dana L, McMahon, Frank J, Farrell, Francis X, Tullai, Jennifer, Jolliffe, Linda K

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Erythropoietin Concentrations in Cerebrospinal Fluid of Nonhuman Primates and Fetal Sheep following High-Dose Recombinant Erythropoietin von Juul, Sandra E., McPherson, Ronald J., Farrell, Francis X., Jolliffe, Linda, Ness, Dana J., Gleason, Christine A.

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