Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis von Radzisheuskaya, Aliaksandra, Shliaha, Pavel V., Grinev, Vasily V., Shlyueva, Daria, Damhofer, Helene, Koche, Richard, Gorshkov, Vladimir, Kovalchuk, Sergey, Zhan, Yingqian, Rodriguez, Keli L., Johnstone, Andrea L., Keogh, Michael-C, Hendrickson, Ronald C., Jensen, Ole N., Helin, Kristian

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Inhibition of NADPH oxidase activation in oligodendrocytes reduces cytotoxicity following trauma von Johnstone, Joshua T, Morton, Paul D, Jayakumar, Arumugam R, Johnstone, Andrea L, Gao, Han, Bracchi-Ricard, Valerie, Pearse, Damien D, Norenberg, Michael D, Bethea, John R

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BET bromodomain proteins are required for glioblastoma cell proliferation von Pastori, Chiara, Daniel, Mark, Penas, Clara, Volmar, Claude-Henry, Johnstone, Andrea L, Brothers, Shaun P, Graham, Regina M, Allen, Bryce, Sarkaria, Jann N, Komotar, Ricardo J, Wahlestedt, Claes, Ayad, Nagi G

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Chromatin structure and its chemical modifications regulate the ubiquitin ligase substrate selectivity of UHRF1 von Vaughan, Robert M., Dickson, Bradley M., Whelihan, Matthew F., Johnstone, Andrea L., Cornett, Evan M., Cheek, Marcus A., Ausherman, Christine A., Cowles, Martis W., Sun, Zu-Wen, Rothbart, Scott B.

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Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies von Shah, Rohan N., Grzybowski, Adrian T., Cornett, Evan M., Johnstone, Andrea L., Dickson, Bradley M., Boone, Brandon A., Cheek, Marcus A., Cowles, Martis W., Maryanski, Danielle, Meiners, Matthew J., Tiedemann, Rochelle L., Vaughan, Robert M., Arora, Neha, Sun, Zu-Wen, Rothbart, Scott B., Keogh, Michael-Christopher, Ruthenburg, Alexander J.

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Aminobenzotriazole inhibits and induces several key drug metabolizing enzymes complicating its utility as a pan CYP inhibitor for reaction phenotyping von Aluri, Krishna C., Slavsky, Marina, Tan, Ying, Whitcher‐Johnstone, Andrea, Zhang, Zhoupeng, Hariparsad, Niresh, Ramsden, Diane

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Quantification of citrullinated histones: Development of an improved assay to reliably quantify nucleosomal H3Cit in human plasma von Thålin, Charlotte, Aguilera, Katherina, Hall, Nathan W., Marunde, Matthew R., Burg, Jonathan M., Rosell, Axel, Daleskog, Maud, Månsson, Maja, Hisada, Yohei, Meiners, Matthew J., Sun, Zu‐Wen, Whelihan, Matthew F., Cheek, Marcus A., Howard, Sarah A., Saxena‐Beem, Shruti, Noubouossie, Denis F., Key, Nigel S., Sheikh, Saira Z., Keogh, Michael‐Christopher, Cowles, Martis W., Lundström, Staffan, Mackman, Nigel, Wallén, Håkan, Johnstone, Andrea L.

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Neutrophil Extracellular Trap Formation and Syndecan-1 Shedding Are Increased After Trauma von Goswami, Julie, MacArthur, Taleen, Bailey, Kent, Spears, Grant, Kozar, Rosemary A., Auton, Matthew, Dong, Jing-Fei, Key, Nigel S., Heller, Stephanie, Loomis, Erica, Hall, Nathan W., Johnstone, Andrea L., Park, Myung S.

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Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways von Johnstone, Andrea L., Andrade, Nadja S., Barbier, Estelle, Khomtchouk, Bohdan B., Rienas, Christopher A., Lowe, Kenneth, Van Booven, Derek J., Domi, Esi, Esanov, Rustam, Vilca, Samara, Tapocik, Jenica D., Rodriguez, Keli, Maryanski, Danielle, Keogh, Michael Christopher, Meinhardt, Marcus W., Sommer, Wolfgang H., Heilig, Markus, Zeier, Zane, Wahlestedt, Claes

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EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia von Johnstone, Andrea L., O'Reilly, Jiaqi J., Patel, Annika J., Guo, Zhihong, Andrade, Nadja S., Magistri, Marco, Nathanson, Lubov, Esanov, Rustam, Miller, Brooke H., Turecki, Gustavo, Brothers, Shaun P., Zeier, Zane, Wahlestedt, Claes

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Chromatin Immunoprecipitation (ChIP) to Study DNA–Protein Interactions von Small, Eliza C., Maryanski, Danielle N., Rodriguez, Keli L., Harvey, Kevin J., Keogh, Michael-C., Johnstone, Andrea L.

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Exploring the human 3D small intestinal model (epiintestinaltm) for improved prediction of oral absorption, metabolism and complex drug-drug interactions of small molecule drugs von Chothe, Paresh, Whitcher-Johnstone, Andrea, Hariparsad, Niresh, Ramsden, Diane

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Elacridar leads to a much more pronounced boost in dog absorption than expected based on available non-clinical and clinical observations von Ramsden, Diane, Chothe, Paresh, Whitcher-Johnstone, Andrea, Hariparsad, Niresh

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Ischemic Preconditioning Confers Epigenetic Repression of Mtor and Induction of Autophagy Through G9a‐Dependent H3K9 Dimethylation von Gidlöf, Olof, Johnstone, Andrea L., Bader, Kerstin, Khomtchouk, Bohdan B., O'Reilly, Jiaqi J., Celik, Selvi, Van Booven, Derek J., Wahlestedt, Claes, Metzler, Bernhard, Erlinge, David

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Bromodomain inhibitors regulate the C9ORF72 locus in ALS von Zeier, Zane, Esanov, Rustam, Belle, Kinsley C., Volmar, Claude-Henry, Johnstone, Andrea L., Halley, Paul, DeRosa, Brooke A., Khoury, Nathalie, van Blitterswijk, Marka, Rademakers, Rosa, Albert, Jeffrey, Brothers, Shaun P., Wuu, Joanne, Dykxhoorn, Derek M., Benatar, Michael, Wahlestedt, Claes

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A Hyperactive Neutrophil Phenotype in Patients With Refractory Periodontitis von Johnstone, Andrea M., Koh, Adeline, Goldberg, Michael B., Glogauer, Michael

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Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1 von GALOIAN, KARINA, QURESHI, AMIR, D'IPPOLITO, GIANLUCA, SCHILLER, PAUL C, MOLINARI, MARCO, JOHNSTONE, ANDREA L, BROTHERS, SHAUN P, PAZ, ANA C, TEMPLE, H.T

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A chemical genetic approach identifies piperazine antipsychotics as promoters of CNS neurite growth on inhibitory substrates von Johnstone, Andrea L., Reierson, Gillian W., Smith, Robin P., Goldberg, Jeffrey L., Lemmon, Vance P., Bixby, John L.

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Biomarkers of thromboinflammation correlate to COVID-19 infection and admission status in emergency department patients von Goswami, Julie, MacArthur, Taleen A., Sridharan, Meera, Tange, Julie, Kirmse, Andrew J., Lundell, Kaitlin A., Chen, Dong, Auton, Matthew T., Chon, Tony Y., Hurt, Ryan T., Salonen, Bradley R., Ganesh, Ravindra, Erben, Young M., Marquez, Christopher P., Dong, Jing-Fei, Kozar, Rosemary A., Heller, Stephanie F., Loomis, Erica A., Johnstone, Andrea L., Bailey, Kent R., Spears, Grant M., Park, Myung S.

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The impact of a CYP2C8-CYP3A4 protein–protein interaction on time dependent inhibition of CYP2C8 von Whitcher-Johnstone, Andrea, Chan, Tom S.

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