The production of 3D tumor spheroids for cancer drug discovery von Sant, Shilpa, Johnston, Paul A.

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Redox cycling compounds generate H2O2 in HTS buffers containing strong reducing reagents—real hits or promiscuous artifacts? von Johnston, Paul A

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Morphology and relationships of the enigmatic stenothecoid pan-brachiopod Stenothecoides—New data from the middle Cambrian Burgess Shale Formation von Johnston, Paul, Streng, Michael

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Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z von Gosai, Sager J, Kwak, Joon Hyeok, Luke, Cliff J, Long, Olivia S, King, Dale E, Kovatch, Kevin J, Johnston, Paul A, Shun, Tong Ying, Lazo, John S, Perlmutter, David H, Silverman, Gary A, Pak, Stephen C

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Detection and impact of hypoxic regions in multicellular tumor spheroid cultures formed by head and neck squamous cell carcinoma cells lines von Close, David A., Johnston, Paul A.

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Miniaturization and characterization of patient derived hepatocellular carcinoma tumor organoid cultures for cancer drug discovery applications von Close, David A., Johnston, Paul A.

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Optimization and calibration of 384-well kinetic Ca2+ mobilization assays for the human transient receptor potential cation channels TRPM8, TRPV1, and TRPA1 von Close, David A., Journigan, V. Blair, Johnston, Paul A.

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The Generation of Three-Dimensional Head and Neck Cancer Models for Drug Discovery in 384-Well Ultra-Low Attachment Microplates von Close, David A., Camarco, Daniel P., Shan, Feng, Kochanek, Stanton J., Johnston, Paul A.

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Production of Uniform 3D Microtumors in Hydrogel Microwell Arrays for Measurement of Viability, Morphology, and Signaling Pathway Activation von Singh, Manjulata, Close, David A, Mukundan, Shilpaa, Johnston, Paul A, Sant, Shilpa

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U-Pb geochronology reveals that hydrothermal dolomitization was coeval to the deposition of the Burgess Shale lagerstätte von McCormick, Cole A., Corlett, Hilary, Roberts, Nick M. W., Johnston, Paul A., Collom, Christopher J., Stacey, Jack, Koeshidayatullah, Ardiansyah, Hollis, Cathy

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Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities von Vázquez Rivera, Alondra, Donald, Heather, Alaoui-El-Azher, Mounia, Skoko, John J, Lazo, John S, Parniak, Michael A, Johnston, Paul A, Sluis-Cremer, Nicolas

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Three dimensional engineered models to study hypoxia biology in breast cancer von Aggarwal, Vaishali, Miranda, Oshin, Johnston, Paul A., Sant, Shilpa

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The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites von Pratt, Susan, Shepard, Robert L, Kandasamy, Ramani A, Johnston, Paul A, Perry, 3rd, William, Dantzig, Anne H

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Characterization of allosteric modulators that disrupt androgen receptor co-activator protein-protein interactions to alter transactivation-Drug leads for metastatic castration res... von Fancher, Ashley T, Hua, Yun, Close, David A, Xu, Wei, McDermott, Lee A, Strock, Christopher J, Santiago, Ulises, Camacho, Carlos J, Johnston, Paul A

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Replacement of the hydroxamic acid group in the selective HDAC8 inhibitor PCI-34051 von Long, Keith, Close, David A., Johnston, Paul A., Huryn, Donna M.

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High-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions von Hua, Yun, Shun, Tong Ying, Strock, Christopher J, Johnston, Paul A

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Identifying Actives from HTS Data Sets: Practical Approaches for the Selection of an Appropriate HTS Data-Processing Method and Quality Control Review von Shun, Tong Ying, Lazo, John S., Sharlow, Elizabeth R., Johnston, Paul A.

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Phenotypic characterization of the Hordeum bulbosum derived leaf rust resistance genes Rph22 and Rph26 in barley von Yu, Xiaohui, Casonato, Seona, Jones, Eirian, Butler, Ruth C., Johnston, Paul A., Chng, Soonie

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Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate C... von Johnston, Paul A, Nguyen, Minh M, Dar, Javid A, Ai, Junkui, Wang, Yujuan, Masoodi, Khalid Z, Shun, Tongying, Shinde, Sunita, Camarco, Daniel P, Hua, Yun, Huryn, Donna M, Wilson, Gabriela Mustata, Lazo, John S, Nelson, Joel B, Wipf, Peter, Wang, Zhou

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Discovery of Non-peptide Small Molecule Allosteric Modulators of the Src-family Kinase, Hck von Dorman, Heather R, Close, David, Wingert, Bentley M, Camacho, Carlos J, Johnston, Paul A, Smithgall, Thomas E

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