Ligand and Target Discovery by Fragment-Based Screening in Human Cells von Parker, Christopher G., Galmozzi, Andrea, Wang, Yujia, Correia, Bruno E., Sasaki, Kenji, Joslyn, Christopher M., Kim, Arthur S., Cavallaro, Cullen L., Lawrence, R. Michael, Johnson, Stephen R., Narvaiza, Iñigo, Saez, Enrique, Cravatt, Benjamin F.

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Aspartic Acid Isomerization Characterized by High Definition Mass Spectrometry Significantly Alters the Bioactivity of a Novel Toxin from Poecilotheria von Johnson, Stephen R., Rikli, Hillary G.

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A positive allosteric modulator of α7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia von Kalappa, Bopanna I, Sun, Fen, Johnson, Stephen R, Jin, Kunlin, Uteshev, Victor V

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A reexamination of poneratoxin from the venom of the bullet ant Paraponera clavata von Johnson, Stephen R., Rikli, Hillary G., Schmidt, Justin O., Evans, M. Steven

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The Trouble with QSAR (or How I Learned To Stop Worrying and Embrace Fallacy) von Johnson, Stephen R

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3D Matched Pairs: Integrating Ligand- and Structure-Based Knowledge for Ligand Design and Receptor Annotation von Posy, Shana L, Claus, Brian L, Pokross, Matt E, Johnson, Stephen R

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Synergy and Complementarity between Focused Machine Learning and Physics-Based Simulation in Affinity Prediction von Cleves, Ann E, Johnson, Stephen R, Jain, Ajay N

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Electrostatic-field and surface-shape similarity for virtual screening and pose prediction von Cleves, Ann E., Johnson, Stephen R., Jain, Ajay N.

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Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain von Tokarski, John S., Zupa-Fernandez, Adriana, Tredup, Jeffrey A., Pike, Kristen, Chang, ChiehYing, Xie, Dianlin, Cheng, Lihong, Pedicord, Donna, Muckelbauer, Jodi, Johnson, Stephen R., Wu, Sophie, Edavettal, Suzanne C., Hong, Yang, Witmer, Mark R., Elkin, Lisa L., Blat, Yuval, Pitts, William J., Weinstein, David S., Burke, James R.

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Approaches for machine learning intermolecular interaction energies and application to energy components from symmetry adapted perturbation theory von Metcalf, Derek P., Koutsoukas, Alexios, Spronk, Steven A., Claus, Brian L., Loughney, Deborah A., Johnson, Stephen R., Cheney, Daniel L., Sherrill, C. David

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Downregulation of vascular endothelial growth factor and induction of tumor dormancy by 15‐lipoxygenase‐2 in prostate cancer von Tang, Yong, Wang, Man‐Tzu, Chen, Yakun, Yang, Dianer, Che, Mingxin, Honn, Kenneth V., Akers, Gregory D., Johnson, Stephen R., Nie, Daotai

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Molecular Properties That Influence the Oral Bioavailability of Drug Candidates von Veber, Daniel F, Johnson, Stephen R, Cheng, Hung-Yuan, Smith, Brian R, Ward, Keith W, Kopple, Kenneth D

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Boosting Endogenous Resistance of Brain to Ischemia von Sun, Fen, Johnson, Stephen R., Jin, Kunlin, Uteshev, Victor V.

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A positive allosteric modulator of alpha 7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia von Kalappa, Bopanna I, Sun, Fen, Johnson, Stephen R, Jin, Kunlin, Uteshev, Victor V

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Estimation of hERG inhibition of drug candidates using multivariate property and pharmacophore SAR von Johnson, Stephen R., Yue, Hongwen, Conder, Mary Lee, Shi, Hong, Doweyko, Arthur M., Lloyd, John, Levesque, Paul

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Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase von Sivaprakasam, Prasanna, Wang, Zhongyu, Meanwell, Nicholas A., Khan, Javed A., Langley, David R., Johnson, Stephen R., Li, Guo, Pendri, Annapurna, Connolly, Timothy P., Gao, Mian, Camac, Daniel M., Klakouski, Cheryl, Zvyaga, Tatyana, Cianci, Christopher, McAuliffe, Brian, Ding, Bo, Discotto, Linda, Krystal, Mark R., Jenkins, Susan, Peese, Kevin M., Narasimhulu Naidu, B.

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Benzonatate inhibition of voltage-gated sodium currents von Evans, M. Steven, Maglinger, G. Benton, Fletcher, Anita M., Johnson, Stephen R.

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Trends in Kinase Selectivity: Insights for Target Class-Focused Library Screening von Posy, Shana L, Hermsmeier, Mark A, Vaccaro, Wayne, Ott, Karl-Heinz, Todderud, Gordon, Lippy, Jonathan S, Trainor, George L, Loughney, Deborah A, Johnson, Stephen R

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Recent progress in the computational prediction of aqueous solubility and absorption von Johnson, Stephen R, Zheng, Weifan

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To measure is to know: an approach to CADD performance metrics von Loughney, Deborah, Claus, Brian L., Johnson, Stephen R.

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