Dual Blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) Pathways Synergistically Inhibits Rhabdomyosarcoma Cell Growth In Vitro and In Vivo von RENSHAW, Jane, TAYLOR, Kathryn R, SELFE, Joanna L, THWAY, Khin, PIETSCH, Torsten, PEARSON, Andrew D, SHIPLEY, Janet, BISHOP, Ryan, VALENTI, Melanie, DE HAVEN BRANDON, Alexis, GOWAN, Sharon, ECCLES, Suzanne A, RUDDLE, Ruth R, JOHNSON, Louise D, RAYNAUD, Florence I

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Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders von Bellenie, Benjamin R, Cheung, Kwai-Ming J, Varela, Ana, Pierrat, Olivier A, Collie, Gavin W, Box, Gary M, Bright, Michael D, Gowan, Sharon, Hayes, Angela, Rodrigues, Matthew J, Shetty, Kartika N, Carter, Michael, Davis, Owen A, Henley, Alan T, Innocenti, Paolo, Johnson, Louise D, Liu, Manjuan, de Klerk, Selby, Le Bihan, Yann-Vaï, Lloyd, Matthew G, McAndrew, P. Craig, Shehu, Erald, Talbot, Rachel, Woodward, Hannah L, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M, Raynaud, Florence I, Rossanese, Olivia W, Hoelder, Swen

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Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket von Lloyd, Matthew G, Huckvale, Rosemary, Cheung, Kwai-Ming J, Rodrigues, Matthew J, Collie, Gavin W, Pierrat, Olivier A, Gatti Iou, Mahad, Carter, Michael, Davis, Owen A, McAndrew, P. Craig, Gunnell, Emma, Le Bihan, Yann-Vaï, Talbot, Rachel, Henley, Alan T, Johnson, Louise D, Hayes, Angela, Bright, Michael D, Raynaud, Florence I, Meniconi, Mirco, Burke, Rosemary, van Montfort, Rob L. M, Rossanese, Olivia W, Bellenie, Benjamin R, Hoelder, Swen

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Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones von Harnden, Alice C., Davis, Owen A., Box, Gary M., Hayes, Angela, Johnson, Louise D., Henley, Alan T., de Haven Brandon, Alexis K., Valenti, Melanie, Cheung, Kwai-Ming J., Brennan, Alfie, Huckvale, Rosemary, Pierrat, Olivier A., Talbot, Rachel, Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, de Klerk, Selby, McAndrew, Peter Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen

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Improved Binding Affinity and Pharmacokinetics Enable Sustained Degradation of BCL6 In Vivo von Huckvale, Rosemary, Harnden, Alice C., Cheung, Kwai-Ming J., Pierrat, Olivier A., Talbot, Rachel, Box, Gary M., Henley, Alan T., de Haven Brandon, Alexis K., Hallsworth, Albert E., Bright, Michael D., Akpinar, Hafize Aysin, Miller, Daniel S. J., Tarantino, Dalia, Gowan, Sharon, Hayes, Angela, Gunnell, Emma A., Brennan, Alfie, Davis, Owen A., Johnson, Louise D., de Klerk, Selby, McAndrew, Craig, Le Bihan, Yann-Vaï, Meniconi, Mirco, Burke, Rosemary, Kirkin, Vladimir, van Montfort, Rob L. M., Raynaud, Florence I., Rossanese, Olivia W., Bellenie, Benjamin R., Hoelder, Swen

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Virus–virus interactions impact the population dynamics of influenza and the common cold von Nickbakhsh, Sema, Mair, Colette, Matthews, Louise, Reeve, Richard, Johnson, Paul C. D., Thorburn, Fiona, von Wissmann, Beatrix, Reynolds, Arlene, McMenamin, James, Gunson, Rory N., Murcia, Pablo R.

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Visual Attentional Orienting by Eye Gaze: A Meta-Analytic Review of the Gaze-Cueing Effect von McKay, Kate T., Grainger, Sarah A., Coundouris, Sarah P., Skorich, Daniel P., Phillips, Louise H., Henry, Julie D.

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Pervasive shifts in forest dynamics in a changing world von McDowell, Nate G., Allen, Craig D., Anderson-Teixeira, Kristina, Aukema, Brian H., Bond-Lamberty, Ben, Chini, Louise, Clark, James S., Dietze, Michael, Grossiord, Charlotte, Hanbury-Brown, Adam, Hurtt, George C., Jackson, Robert B., Johnson, Daniel J., Kueppers, Lara, Lichstein, Jeremy W., Ogle, Kiona, Poulter, Benjamin, Pugh, Thomas A. M., Seidl, Rupert, Turner, Monica G., Uriarte, Maria, Walker, Anthony P., Xu, Chonggang

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Chemical and morphological filters in a specialized floral mimicry system von Martos, Florent, Cariou, Marie‐Louise, Pailler, Thierry, Fournel, Jacques, Bytebier, Benny, Johnson, Steven D.

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Genetic mechanisms of critical illness in COVID-19 von Pairo-Castineira, Erola, Clohisey, Sara, Klaric, Lucija, Bretherick, Andrew D., Rawlik, Konrad, Pasko, Dorota, Walker, Susan, Parkinson, Nick, Fourman, Max Head, Russell, Clark D., Furniss, James, Richmond, Anne, Gountouna, Elvina, Wrobel, Nicola, Harrison, David, Wang, Bo, Wu, Yang, Meynert, Alison, Griffiths, Fiona, Oosthuyzen, Wilna, Kousathanas, Athanasios, Moutsianas, Loukas, Yang, Zhijian, Zhai, Ranran, Zheng, Chenqing, Grimes, Graeme, Beale, Rupert, Millar, Jonathan, Shih, Barbara, Keating, Sean, Zechner, Marie, Haley, Chris, Porteous, David J., Hayward, Caroline, Yang, Jian, Knight, Julian, Summers, Charlotte, Shankar-Hari, Manu, Klenerman, Paul, Turtle, Lance, Ho, Antonia, Moore, Shona C., Hinds, Charles, Horby, Peter, Nichol, Alistair, Maslove, David, Ling, Lowell, McAuley, Danny, Montgomery, Hugh, Walsh, Timothy, Pereira, Alexandre C., Renieri, Alessandra, Shen, Xia, Ponting, Chris P., Fawkes, Angie, Tenesa, Albert, Caulfield, Mark, Scott, Richard, Rowan, Kathy, Murphy, Lee, Openshaw, Peter J. M., Semple, Malcolm G., Law, Andrew, Vitart, Veronique, Wilson, James F., Baillie, J. Kenneth

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Population-level impact and herd effects following human papillomavirus vaccination programmes: a systematic review and meta-analysis von Drolet, Mélanie, PhD, Bénard, Élodie, BSc, Boily, Marie-Claude, PhD, Ali, Hammad, PhD, Baandrup, Louise, MD, Bauer, Heidi, MD, Beddows, Simon, PhD, Brisson, Jacques, DSc, Brotherton, Julia M L, BMed, Cummings, Teresa, BA, Donovan, Basil, MD, Fairley, Christopher K, PhD, Flagg, Elaine W, PhD, Johnson, Anne M, MD, Kahn, Jessica A, MD, Kavanagh, Kimberley, PhD, Kjaer, Susanne K, MD, Kliewer, Erich V, PhD, Lemieux-Mellouki, Philippe, MSc, Markowitz, Lauri, MD, Mboup, Aminata, MSc, Mesher, David, MSc, Niccolai, Linda, PhD, Oliphant, Jeannie, FAChSHM, Pollock, Kevin G, PhD, Soldan, Kate, PhD, Sonnenberg, Pam, PhD, Tabrizi, Sepehr N, PhD, Tanton, Clare, PhD, Brisson, Marc, Dr

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Apolipoprotein E–low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner von Johnson, Lance A, Olsen, Reid H.J, Merkens, Louise S, DeBarber, Andrea, Steiner, Robert D, Sullivan, Patrick M, Maeda, Nobuyo, Raber, Jacob

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On-chip preparation of nanoscale contrast agents towards high-resolution ultrasound imaging von Peyman, Sally A, McLaughlan, James R, Abou-Saleh, Radwa H, Marston, Gemma, Johnson, Benjamin R G, Freear, Steven, Coletta, P Louise, Markham, Alexander F, Evans, Stephen D

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Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen von Lim, Hwee Ying, Lim, Sheau Yng, Tan, Chek Kun, Thiam, Chung Hwee, Goh, Chi Ching, Carbajo, Daniel, Chew, Samantha Hui Shang, See, Peter, Chakarov, Svetoslav, Wang, Xiao Nong, Lim, Li Hui, Johnson, Louise A., Lum, Josephine, Fong, Chui Yee, Bongso, Ariff, Biswas, Arijit, Goh, Chern, Evrard, Maximilien, Yeo, Kim Pin, Basu, Ranu, Wang, Jun Kit, Tan, Yingrou, Jain, Rohit, Tikoo, Shweta, Choong, Cleo, Weninger, Wolfgang, Poidinger, Michael, Stanley, Richard E., Collin, Matthew, Tan, Nguan Soon, Ng, Lai Guan, Jackson, David G., Ginhoux, Florent, Angeli, Véronique

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Call to Action: Maternal Health and Saving Mothers: A Policy Statement From the American Heart Association von Mehta, Laxmi S., Sharma, Garima, Creanga, Andreea A., Hameed, Afshan B., Hollier, Lisa M., Johnson, Janay C., Leffert, Lisa, McCullough, Louise D., Mujahid, Mahasin S., Watson, Karol, White, Courtney J.

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Endovascular Proximal Forearm Arteriovenous Fistula for Hemodialysis Access: Results of the Prospective, Multicenter Novel Endovascular Access Trial (NEAT) von Lok, Charmaine E., MD, MSc, Rajan, Dheeraj K., MD, Clement, Jason, MD, Kiaii, Mercedeh, MD, Sidhu, Ravi, MD, MEd, Thomson, Ken, MD, Buldo, George, MD, Dipchand, Christine, MD, MSc, Moist, Louise, MD, MSc, Sasal, Joanna, MD

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Clinical and prognostic differences in oropharyngeal squamous cell carcinoma in USA and Denmark, two HPV high-prevalence areas von Carlander, Amanda-Louise Fenger, Bendtsen, Simone Kloch, Rasmussen, Jacob H., Jakobsen, Kathrine Kronberg, Garset-Zamani, Martin, Grønhøj, Christian, Friborg, Jeppe, Hutcheson, Katherine, Johnson, Faye M., Fuller, Clifton D., Moreno, Amy C., Babarinde, Toyin, Gross, Neil D., Myers, Jeffrey N., von Buchwald, Christian

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Effect of Robot-Assisted Radical Cystectomy With Intracorporeal Urinary Diversion vs Open Radical Cystectomy on 90-Day Morbidity and Mortality Among Patients With Bladder Cancer: A... von Catto, James W. F, Khetrapal, Pramit, Ricciardi, Federico, Ambler, Gareth, Williams, Norman R, Al-Hammouri, Tarek, Khan, Muhammad Shamim, Thurairaja, Ramesh, Nair, Rajesh, Feber, Andrew, Dixon, Simon, Nathan, Senthil, Briggs, Tim, Sridhar, Ashwin, Ahmad, Imran, Bhatt, Jaimin, Charlesworth, Philip, Blick, Christopher, Cumberbatch, Marcus G, Hussain, Syed A, Kotwal, Sanjeev, Koupparis, Anthony, McGrath, John, Noon, Aidan P, Rowe, Edward, Vasdev, Nikhil, Hanchanale, Vishwanath, Hagan, Daryl, Brew-Graves, Chris, Kelly, John D

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Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients von Ridker, Paul M, Revkin, James, Amarenco, Pierre, Brunell, Robert, Curto, Madelyn, Civeira, Fernando, Flather, Marcus, Glynn, Robert J, Gregoire, Jean, Jukema, J. Wouter, Karpov, Yuri, Kastelein, John J.P, Koenig, Wolfgang, Lorenzatti, Alberto, Manga, Pravin, Masiukiewicz, Urszula, Miller, Michael, Mosterd, Arend, Murin, Jan, Nicolau, Jose C, Nissen, Steven, Ponikowski, Piotr, Santos, Raul D, Schwartz, Pamela F, Soran, Handrean, White, Harvey, Wright, R. Scott, Vrablik, Michal, Yunis, Carla, Shear, Charles L, Tardif, Jean-Claude

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Surveillance Breast MRI and Mammography: Comparison in Women with a Personal History of Breast Cancer von Wernli, Karen J, Ichikawa, Laura, Kerlikowske, Karla, Buist, Diana S M, Brandzel, Susan D, Bush, Mary, Johnson, Dianne, Henderson, Louise M, Nekhlyudov, Larissa, Onega, Tracy, Sprague, Brian L, Lee, Janie M, Lehman, Constance D, Miglioretti, Diana L

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