An atlas of substrate specificities for the human serine/threonine kinome von Johnson, Jared L., Yaron, Tomer M., Huntsman, Emily M., Kerelsky, Alexander, Song, Junho, Regev, Amit, Lin, Ting-Yu, Liberatore, Katarina, Cizin, Daniel M., Cohen, Benjamin M., Vasan, Neil, Ma, Yilun, Krismer, Konstantin, Robles, Jaylissa Torres, van de Kooij, Bert, van Vlimmeren, Anne E., Andrée-Busch, Nicole, Käufer, Norbert F., Dorovkov, Maxim V., Ryazanov, Alexey G., Takagi, Yuichiro, Kastenhuber, Edward R., Goncalves, Marcus D., Hopkins, Benjamin D., Elemento, Olivier, Taatjes, Dylan J., Maucuer, Alexandre, Yamashita, Akio, Degterev, Alexei, Uduman, Mohamed, Lu, Jingyi, Landry, Sean D., Zhang, Bin, Cossentino, Ian, Linding, Rune, Blenis, John, Hornbeck, Peter V., Turk, Benjamin E., Yaffe, Michael B., Cantley, Lewis C.

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Identification of SARS-CoV-2 inhibitors using lung and colonic organoids von Han, Yuling, Duan, Xiaohua, Yang, Liuliu, Nilsson-Payant, Benjamin E., Wang, Pengfei, Duan, Fuyu, Tang, Xuming, Yaron, Tomer M., Zhang, Tuo, Uhl, Skyler, Bram, Yaron, Richardson, Chanel, Zhu, Jiajun, Zhao, Zeping, Redmond, David, Houghton, Sean, Nguyen, Duc-Huy T., Xu, Dong, Wang, Xing, Jessurun, Jose, Borczuk, Alain, Huang, Yaoxing, Johnson, Jared L., Liu, Yuru, Xiang, Jenny, Wang, Hui, Cantley, Lewis C., tenOever, Benjamin R., Ho, David D., Pan, Fong Cheng, Evans, Todd, Chen, Huanhuan Joyce, Schwartz, Robert E., Chen, Shuibing

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Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells von Antonyak, Marc A, Li, Bo, Boroughs, Lindsey K, Johnson, Jared L, Druso, Joseph E, Bryant, Kirsten L, Holowka, David A, Cerione, Richard A

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Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor von Darabedian, Narek, Ji, Wenzhi, Fan, Mengyang, Lin, Shan, Seo, Hyuk-Soo, Vinogradova, Ekaterina V., Yaron, Tomer M., Mills, Evanna L., Xiao, Haopeng, Senkane, Kristine, Huntsman, Emily M., Johnson, Jared L., Che, Jianwei, Cantley, Lewis C., Cravatt, Benjamin F., Dhe-Paganon, Sirano, Stegmaier, Kimberly, Zhang, Tinghu, Gray, Nathanael S., Chouchani, Edward T.

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New Insights into How the Rho Guanine Nucleotide Dissociation Inhibitor Regulates the Interaction of Cdc42 with Membranes von Johnson, Jared L., Erickson, Jon W., Cerione, Richard A.

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Phosphoproteomics-directed manipulation reveals SEC22B as a hepatocellular signaling node governing metabolic actions of glucagon von Wu, Yuqin, Foollee, Ashish, Chan, Andrea Y., Hille, Susanne, Hauke, Jana, Challis, Matthew P., Johnson, Jared L., Yaron, Tomer M., Mynard, Victoria, Aung, Okka H., Cleofe, Maria Almira S., Huang, Cheng, Lim Kam Sian, Terry C. C., Rahbari, Mohammad, Gallage, Suchira, Heikenwalder, Mathias, Cantley, Lewis C., Schittenhelm, Ralf B., Formosa, Luke E., Smith, Greg C., Okun, Jürgen G., Müller, Oliver J., Rusu, Patricia M., Rose, Adam J.

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SARS-CoV-2 hijacks p38β/MAPK11 to promote virus replication von Higgins, Christina A, Nilsson-Payant, Benjamin E, Bonaventure, Boris, Kurland, Andrew P, Ye, Chengjin, Yaron, Tomer M, Johnson, Jared L, Adhikary, Prithy, Golynker, Ilona, Panis, Maryline, Danziger, Oded, Rosenberg, Brad R, Cantley, Lewis C, Martínez-Sobrido, Luis, tenOever, Benjamin, Johnson, Jeffrey R

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C-terminal Di-arginine Motif of Cdc42 Protein Is Essential for Binding to Phosphatidylinositol 4,5-Bisphosphate-containing Membranes and Inducing Cellular Transformation von Johnson, Jared L., Erickson, Jon W., Cerione, Richard A.

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The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation von Lee, Ho-Soo, Lin, Zhonghui, Chae, Sunyoung, Yoo, Young-Suk, Kim, Byung-Gyu, Lee, Youngsoo, Johnson, Jared L., Kim, You-Sun, Cantley, Lewis C., Lee, Chang-Woo, Yu, Hongtao, Cho, Hyeseong

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Epinephrine inhibits PI3Kα via the Hippo kinases von Lin, Ting-Yu, Ramsamooj, Shakti, Perrier, Tiffany, Liberatore, Katarina, Lantier, Louise, Vasan, Neil, Karukurichi, Kannan, Hwang, Seo-Kyoung, Kesicki, Edward A., Kastenhuber, Edward R., Wiederhold, Thorsten, Yaron, Tomer M., Huntsman, Emily M., Zhu, Mengmeng, Ma, Yilun, Paddock, Marcia N., Zhang, Guoan, Hopkins, Benjamin D., McGuinness, Owen, Schwartz, Robert E., Ersoy, Baran A., Cantley, Lewis C., Johnson, Jared L., Goncalves, Marcus D.

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A Unique Role for Heat Shock Protein 70 and Its Binding Partner Tissue Transglutaminase in Cancer Cell Migration von Boroughs, Lindsey K., Antonyak, Marc A., Johnson, Jared L., Cerione, Richard A.

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Prenylation and Membrane Localization of Cdc42 Are Essential for Activation by DOCK7 von Zhou, Yeyun, Johnson, Jared L, Cerione, Richard A, Erickson, Jon W

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Dietary fructose improves intestinal cell survival and nutrient absorption von Taylor, Samuel R., Ramsamooj, Shakti, Liang, Roger J., Katti, Alyna, Pozovskiy, Rita, Vasan, Neil, Hwang, Seo-Kyoung, Nahiyaan, Navid, Francoeur, Nancy J., Schatoff, Emma M., Johnson, Jared L., Shah, Manish A., Dannenberg, Andrew J., Sebra, Robert P., Dow, Lukas E., Cantley, Lewis C., Rhee, Kyu Y., Goncalves, Marcus D.

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Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors von Vasan, Neil, Razavi, Pedram, Johnson, Jared L, Shao, Hong, Shah, Hardik, Antoine, Alesia, Ladewig, Erik, Gorelick, Alexander, Lin, Ting-Yu, Toska, Eneda, Xu, Guotai, Kazmi, Abiha, Chang, Matthew T, Taylor, Barry S, Dickler, Maura N, Jhaveri, Komal, Chandarlapaty, Sarat, Rabadan, Raul, Reznik, Ed, Smith, Melissa L, Sebra, Robert, Schimmoller, Frauke, Wilson, Timothy R, Friedman, Lori S, Cantley, Lewis C, Scaltriti, Maurizio, Baselga, José

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Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors von Robert, Thomas, Johnson, Jared L., Guichaoua, Roxane, Yaron, Tomer M., Bach, Stephane, Cantley, Lewis C., Colas, Pierre

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Evaluating air-water and NAPL-water interfacial adsorption and retention of Perfluorocarboxylic acids within the Vadose zone von Silva, Jeff A.K., Martin, William A., Johnson, Jared L., McCray, John E.

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RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer von Jbara, Amina, Lin, Kuan-Ting, Stossel, Chani, Siegfried, Zahava, Shqerat, Haya, Amar-Schwartz, Adi, Elyada, Ela, Mogilevsky, Maxim, Raitses-Gurevich, Maria, Johnson, Jared L., Yaron, Tomer M., Ovadia, Ofek, Jang, Gun Ho, Danan-Gotthold, Miri, Cantley, Lewis C., Levanon, Erez Y., Gallinger, Steven, Krainer, Adrian R., Golan, Talia, Karni, Rotem

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Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1) von Balasuriya, Nileeka, Davey, Norman E., Johnson, Jared L., Liu, Huadong, Biggar, Kyle K., Cantley, Lewis C., Li, Shawn Shun-Cheng, O'Donoghue, Patrick

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Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation von Geffen, Yifat, Anand, Shankara, Akiyama, Yo, Yaron, Tomer M., Song, Yizhe, Johnson, Jared L., Govindan, Akshay, Li, Yize, Huntsman, Emily, Wang, Liang-Bo, Birger, Chet, Heiman, David I., Zhang, Qing, Miller, Mendy, Calinawan, Anna, Belkin, Saveliy, Kerelsky, Alexander, Clauser, Karl R., Krug, Karsten, Satpathy, Shankha, Payne, Samuel H., Mani, D.R., Gillette, Michael A., Dhanasekaran, Saravana M., Thiagarajan, Mathangi, Mesri, Mehdi, Rodriguez, Henry, Robles, Ana I., Lazar, Alexander J., Ding, Li, Getz, Gad, An, Eunkyung, Anurag, Meenakshi, Bavarva, Jasmin, Birrer, Michael J., Cao, Song, Ceccarelli, Michele, Chinnaiyan, Arul M., Chowdhury, Shrabanti, Colaprico, Antonio, Carr, Steven A., da Veiga Leprevost, Felipe, Day, Corbin, Domagalski, Marcin J., Ellis, Matthew J., Fenyo, David, Foltz, Steven M., Francis, Alicia, Gonzalez Robles, Tania J., Gosline, Sara J.C., Gümüş, Zeynep H., Hiltke, Tara, Hong, Runyu, Hu, Yingwei, Huang, Chen, Iavarone, Antonio, Jewel, Scott D., Katsnelson, Lizabeth, Ketchum, Karen A., Kolodziejczak, Iga, Kumar-Sinha, Chandan, Krug, Karsten, Lei, Jonathan T., Liang, Wen-Wei, Liao, Yuxing, Lindgren, Caleb M., Liu, Tao, Liu, Wenke, Ma, Weiping, McKerrow, Wilson, Mesri, Mehdi, Newton, Chelsea, Omenn, Gilbert S., Paulovich, Amanda G., Petralia, Francesca, Pugliese, Pietro, Reva, Boris, Rodland, Karin D., Ruggles, Kelly V., Rodrigues, Fernanda Martins, Savage, Sara R., Schadt, Eric E., Schnaubelt, Michael, Schraink, Tobias, Shi, Zhiao, Smith, Richard D., Stathias, Vasileios, Storrs, Erik P., Selvan, Myvizhi Esai, Tan, Jimin, Thangudu, Ratna R., Wang, Joshua M., Wang, Pei, Wang, Ying (Cindy), Wen, Bo, Wu, Yige, Yi, Xinpei, Zhang, Bing, Zhang, Xu, Zhang, Zhen

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Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription von Rimel, Jenna K., Poss, Zachary C., Erickson, Benjamin, Maas, Zachary L., Ebmeier, Christopher C., Johnson, Jared L., Decker, Tim-Michael, Yaron, Tomer M., Bradley, Michael J., Hamman, Kristin B., Hu, Shanhu, Malojcic, Goran, Marineau, Jason J., White, Peter W., Brault, Martine, Tao, Limei, DeRoy, Patrick, Clavette, Christian, Nayak, Shraddha, Damon, Leah J., Kaltheuner, Ines H., Bunch, Heeyoun, Cantley, Lewis C., Geyer, Matthias, Iwasa, Janet, Dowell, Robin D., Bentley, David L., Old, William M., Taatjes, Dylan J.

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