The structure of His‐tagged Geobacillus stearothermophilus purine nucleoside phosphorylase reveals a `spanner in the works von Given, Fiona M., Moran, Fuchsia, Johns, Ashleigh S., Titterington, James A., Allison, Timothy M., Crittenden, Deborah L., Johnston, Jodie M.

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Mixed carbonate–siliciclastic tidal sedimentation in the Miocene to Pliocene Bouse Formation, palaeo‐Gulf of California von O’Connell, Brennan, Dorsey, Rebecca J., Hasiotis, Stephen T., Hood, Ashleigh V. S., Reijmer, John

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MCL-1 antagonism enhances the anti-invasive effects of dasatinib in pancreatic adenocarcinoma von Castillo, Lesley, Young, Adelaide I. J., Mawson, Amanda, Schafranek, Pia, Steinmann, Angela M., Nessem, Danielle, Parkin, Ashleigh, Johns, Amber, Chou, Angela, Law, Andrew M. K., Lucas, Morghan C., Murphy, Kendelle J., Deng, Niantao, Gallego-Ortega, David, Caldon, Catherine E., Timpson, Paul, Pajic, Marina, Ormandy, Christopher J., Oakes, Samantha R.

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Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer von Balachandran, Vinod P., Łuksza, Marta, Zhao, Julia N., Makarov, Vladimir, Moral, John Alec, Remark, Romain, Herbst, Brian, Askan, Gokce, Bhanot, Umesh, Senbabaoglu, Yasin, Wells, Daniel K., Cary, Charles Ian Ormsby, Grbovic-Huezo, Olivera, Attiyeh, Marc, Medina, Benjamin, Zhang, Jennifer, Loo, Jennifer, Saglimbeni, Joseph, Abu-Akeel, Mohsen, Zappasodi, Roberta, Riaz, Nadeem, Smoragiewicz, Martin, Kelley, Z. Larkin, Basturk, Olca, Gönen, Mithat, Levine, Arnold J., Allen, Peter J., Fearon, Douglas T., Merad, Miriam, Gnjatic, Sacha, Iacobuzio-Donahue, Christine A., Wolchok, Jedd D., DeMatteo, Ronald P., Chan, Timothy A., Greenbaum, Benjamin D., Merghoub, Taha, Leach, Steven D.

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Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash von Jochems, Simon P, Piddock, Katherine, Rylance, Jamie, Adler, Hugh, Carniel, Beatriz F, Collins, Andrea, Gritzfeld, Jenna F, Hancock, Carole, Hill, Helen, Reiné, Jesus, Seddon, Alexandra, Solórzano, Carla, Sunny, Syba, Trimble, Ashleigh, Wright, Angela D, Zaidi, Seher, Gordon, Stephen B, Ferreira, Daniela M

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Genetic complexity alters drug susceptibility of asexual and gametocyte stages of Plasmodium falciparum to antimalarial candidates von Greyling, Nicola, van der Watt, Mariëtte, Gwarinda, Hazel, van Heerden, Ashleigh, Greenhouse, Bryan, Leroy, Didier, Niemand, Jandeli, Birkholtz, Lyn-Marié

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Progesterone analogue protects stressed photoreceptors via bFGF-mediated calcium influx von Wyse-Jackson, Alice C., Roche, Sarah L., Ruiz-Lopez, Ana M., Moloney, Jennifer N., Byrne, Ashleigh M., Cotter, Thomas G.

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Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial von Lyttle, Mark D, Rainford, Naomi E A, Gamble, Carrol, Messahel, Shrouk, Humphreys, Amy, Hickey, Helen, Woolfall, Kerry, Roper, Louise, Noblet, Joanne, Lee, Elizabeth D, Tate, Paul, Iyer, Anand, Evans, Vicki, Appleton, Richard E, Hardwick, Susie, Messahel, Shrouk, Lee, Elizabeth D, Buchanan, Mark, Lewis, Lucy, Hughes, Sharon, Rogers, Louise, Hopkins, Juliet, Lyttle, Mark D, Fernandez, Daphin, Potter, Sarah, Lavigne-Smith, Holly R, Moulsdale, Phoebe, Ross, James, Ramsey, Natasha, Hacking, Jo, Mullen, Niall, Corrigan, Paul P, Prudhoe, Sarah, Faza, Hani, Robinson, Gisela, Sunley, Rachel C, Unsworth, Vanessa, Criddle, John, Sheedy, Alyce B, Anderson, Mark, Bell, Kathryn, Devine, Kirsty, Scott, Alex, Kumar, Ramesh, Armstrong, Sonia, Sutherland, Emer, Helyer, Sinead, Riozzi, Paul, Cotton, Hannah, Downes, Alice J, Mollard, Helen, Roland, Damian, Gough, Christopher, Finucane, Sonya, Bevan, Catherine, Ramsay, Rebecca, Walton, Emily, Maney, Julie-Ann, Dalzell, Elizabeth, Millar, Muriel, Howells, Rachel J, Appelboam, Andy, Mackle, Daisy, Small, Jennie, Neil, Ashleigh, Choudhery, Vince, MacLeod, Stewart, O'Neill, Thomas, Grahamslaw, Julia, Parikh, Ami, Skene, Imogen, Potier de la Morandiere, Katherine, Wilson, Jill L, Danziger, Donna, Burke, Derek, Ramlakhan, Shammi, Evans, Jayne, Morcombe, Julie, Gormley, Stuart, Barling, Jason M, Cathie, Katrina, Bayreuther, Jane, Ensom, Ruth, Iqbal, Yasser, Rounding, Sarah, Bell, Claire, McLellan, Shona, Nyirenda, Maggie, Crome, Laura, Williamson, Neil, Alcock, Anastasia, Edwards, Sara, Morgan, Jeff, Powell, Colin VE, Ramesh, Chaniyil A, Kamal-Uddin, Solomon, Linney, Mike, Vamvakiti, Katia, Floyd, Sharon, Hobden, Gill

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Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial von Bielicki, Julia A, Stöhr, Wolfgang, Barratt, Sam, Dunn, David, Naufal, Nishdha, Roland, Damian, Sturgeon, Kate, Finn, Adam, Rodriguez-Ruiz, Juan Pablo, Malhotra-Kumar, Surbhi, Powell, Colin, Faust, Saul N, Alcock, Anastasia E, Hall, Dani, Robinson, Gisela, Hawcutt, Daniel B, Lyttle, Mark D, Gibb, Diana M, Sharland, Mike

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History and Speculative Fiction

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Gut Microbiome Composition Is Associated With Future Onset of Crohn’s Disease in Healthy First-Degree Relatives von Raygoza Garay, Juan Antonio, Turpin, Williams, Lee, Sun-Ho, Smith, Michelle I., Goethel, Ashleigh, Griffiths, Anne M., Moayyedi, Paul, Espin-Garcia, Osvaldo, Abreu, Maria, Aumais, Guy L., Bernstein, Charles N., Biron, Irit A., Cino, Maria, Deslandres, Colette, Dotan, Iris, El-Matary, Wael, Feagan, Brian, Guttman, David S., Huynh, Hien, Dieleman, Levinus A., Hyams, Jeffrey S., Jacobson, Kevan, Mack, David, Marshall, John K., Otley, Anthony, Panaccione, Remo, Ropeleski, Mark, Silverberg, Mark S., Steinhart, A. Hillary, Turner, Dan, Yerushalmi, Baruch, Paterson, Andrew D., Xu, Wei, Abreu, Maria, Beck, Paul, Bernstein, Charles, Croitoru, Kenneth, Dieleman, Levinus A., Feagan, Brian, Griffiths, Anne, Guttman, David, Jacobson, Kevan, Kaplan, Gilaad, Krause, Denis O., Madsen, Karen, Marshall, John, Moayyedi, Paul, Ropeleski, Mark, Seidman, Ernest, Silverberg, Mark, Snapper, Scott, Stadnyk, Andy, Steinhart, Hillary, Surette, Michael, Turner, Dan, Walters, Thomas, Vallance, Bruce, Aumais, Guy, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Huynh, Hien, Hyams, Jeffrey S., Mack, David, McGrath, Jerry, Otley, Anthony, Panancionne, Remo, Croitoru, Kenneth

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Impact of COVID-19 Nonpharmaceutical Interventions on Pneumococcal Carriage Prevalence and Density in Vietnam von Nation, Monica Larissa, Manna, Sam, Tran, Hau Phuc, Nguyen, Cattram Duong, Vy, Le Thi Tuong, Uyen, Doan Y, Phuong, Tran Linh, Dai, Vo Thi Trang, Ortika, Belinda Daniela, Wee-Hee, Ashleigh Christina, Beissbarth, Jemima, Hinds, Jason, Bright, Kathryn, Smith-Vaughan, Heidi, Nguyen, Thuong Vu, Mulholland, Kim, Temple, Beth, Satzke, Catherine

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Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation von Turpin, Williams, Dong, Mei, Sasson, Gila, Raygoza Garay, Juan Antonio, Espin-Garcia, Osvaldo, Lee, Sun-Ho, Neustaeter, Anna, Smith, Michelle I., Leibovitzh, Haim, Guttman, David S., Goethel, Ashleigh, Griffiths, Anne M., Huynh, Hien Q., Dieleman, Levinus A., Panaccione, Remo, Steinhart, A. Hillary, Silverberg, Mark S., Aumais, Guy, Jacobson, Kevan, Mack, David, Murthy, Sanjay K., Marshall, John K., Bernstein, Charles N., Abreu, Maria T., Moayyedi, Paul, Paterson, Andrew D., Abreu, Maria, Beck, Paul, Bernstein, Charles, Croitoru, Kenneth, Dieleman, Leo, Feagan, Brian, Griffiths, Anne, Guttman, David, Jacobson, Kevan, Kaplan, Gilaad, Krause, Denis O., Madsen, Karen, Marshall, John, Moayyedi, Paul, Ropeleski, Mark, Seidman, Ernest, Silverberg, Mark, Snapper, Scott, Stadnyk, Andy, Steinhart, Hillary, Surette, Michael, Turner, Dan, Walters, Thomas, Vallance, Bruce, Aumais, Guy, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Huynh, Hien, Hyams, Jeff, Mack, David, McGrath, Jerry, Otley, Anthony, Panancionne, Remo, Baldassano, Robert, Griffiths, Anne M., Hedin, Charlotte, Hussey, Seamus, Hyams, Hien, Keljo, David, Kevans, David, Lees, Charlie, Murthy, Sanjay, Panaccione, Remo, Parekh, Nimisha, Plamondon, Sophie, Radford-Smith, Graham, Rosh, Joel, Rubin, David, Schultz, Michael, Siegel, Corey, Xu, Wei, Croitoru, Kenneth

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Seroprevalence of SARS-CoV-2 antibodies among children receiving primary care in Toronto, Ontario von Aglipay, Mary, Kwong, Jeffrey C., Colwill, Karen, Gringas, Anne-Claude, Tuite, Ashleigh, Mamdani, Muhammad, Keown-Stoneman, Charles, Birken, Catherine, Maguire, Jonathon

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Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer von Chou, Angela, Froio, Danielle, Nagrial, Adnan M, Parkin, Ashleigh, Murphy, Kendelle J, Chin, Venessa T, Wohl, Dalia, Steinmann, Angela, Stark, Rhys, Drury, Alison, Walters, Stacey N, Vennin, Claire, Burgess, Andrew, Pinese, Mark, Chantrill, Lorraine A, Cowley, Mark J, Molloy, Timothy J, Waddell, Nicola, Johns, Amber, Grimmond, Sean M, Chang, David K, Biankin, Andrew V, Sansom, Owen J, Morton, Jennifer P, Grey, Shane T, Cox, Thomas R, Turchini, John, Samra, Jaswinder, Clarke, Stephen J, Timpson, Paul, Gill, Anthony J, Pajic, Marina

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Early Moves: a protocol for a population-based prospective cohort study to establish general movements as an early biomarker of cognitive impairment in infants von Elliott, Catherine, Alexander, Caroline, Salt, Alison, Spittle, Alicia J, Boyd, Roslyn N, Badawi, Nadia, Morgan, Catherine, Silva, Desiree, Geelhoed, Elizabeth, Ware, Robert S, Ali, Alishum, McKenzie, Anne, Bloom, David, Sharp, Mary, Ward, Roslyn, Bora, Samudragupta, Prescott, Susan, Woolfenden, Susan, Le, Vuong, Davidson, Sue-Anne, Thornton, Ashleigh, Finlay-Jones, Amy, Jensen, Lynn, Amery, Natasha, Valentine, Jane, Valentine, Jane, Salt, Alison, Silva, Desiree, Alexander, Caroline, Amery, Natasha, Coenen, Arlette, Morie, Rose, Moore, Jennifer, OConnor, Madeleine, Srinivasjois, Ravisha, Tan, Jason, Jongeling, Brad, Downie, Elayne, Last, Ruth, Sharp, Mary, Wray, John, Davidson, Sue-Anne, Thornton, Ashleigh

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Development and Validation of an Integrative Risk Score for Future Risk of Crohn’s Disease in Healthy First-Degree Relatives: A Multicenter Prospective Cohort Study von Lee, Sun-Ho, Turpin, Williams, Espin-Garcia, Osvaldo, Xu, Wei, Croitoru, Kenneth, Lee, Sun-Ho, Turpin, Williams, Espin-Garcia, Osvaldo, Xu, Wei, Leibovitzh, Haim, Xue, Mingyue, Raygoza Garay, Juan Antonio, Graña-Miraglia, Lucía, Smith, Michelle I., Goethel, Ashleigh, Madsen, Karen L., Avni-Biron, Irit, Dotan, Iris, Weiss, Batia, Panaccione, Remo, Huynh, Hien, Jacobson, Kevan, Aumais, Guy, Mack, David, Griffiths, Anne M., Steinhart, A. Hillary, Silverberg, Mark S., Turner, Dan, Bernstein, Charles N., Feagan, Brian G., Moayyedi, Paul, Paterson, Andrew, Guttman, David S., Abreu, Maria, Beck, Paul, Dieleman, Leo, Kaplan, Gilaad, Krause, Denis O., Marshall, John, Ropeleski, Mark, Seidman, Ernest, Snapper, Scott, Stadnyk, Andy, Surette, Michael, Walters, Thomas, Vallance, Bruce, Bitton, Alain, Cino, Maria, Critch, Jeff, Denson, Lee, Deslandres, Colette, El-Matary, Wael, Herfarth, Hans, Higgins, Peter, Hyams, Jeff, McGrath, Jerry, Otley, Anthony, Croitoru, Kenneth

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Multicentre Post-EVAR Surveillance Evaluation Study (EVAR-SCREEN) von Grima, Matthew J., Karthikesalingam, Alan, Holt, Peter J., Kerr, Daniele, Chetter, Ian, Harrison, Seamus, Sayers, Rob, Roy, Iain, Vallabhaneni, Srinivasa R., Dominic, Pang, Bachoo, Paul, Griffin, John, Lewis, David, Hardman, John, Rihan, Ahmed, Brooks, Marcus, Woodburn, Ken, Godfrey, Dean, Nordon, Ian, Vidal-Diez, Alberto, Stenson, Kate, Bahia, Sandeep, Patterson, Benjamin, Oladokun, Dare, De Bruin, Jorg, Loftus, Ian, Thompson, Matt M., Lowe, Chris, Ashrafi, Mohammed, Ghosh, Jonathan, Ashleigh, Raymond

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Cohort Profile: International Collaboration on Hepatitis C Elimination in HIV Cohorts (InCHEHC) von van Santen, Daniela K, Stewart, Ashleigh, Doyle, Joseph S, Stoové, Mark A, Asselin, Jason, Klein, Marina B, Young, Jim, Berenguer, Juan, Jarrin, Inmaculada, Lacombe, Karine, Wittkop, Linda, Leleux, Olivier, Salmon, Dominique, Bonnet, Fabrice, Rauch, Andri, Mugglin, Catrina, Matthews, Gail, Prins, Maria, Smit, Colette, Boyd, Anders, van der Valk, Marc, Sacks-Davis, Rachel, Hellard, Margaret E

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A Neuroethics Framework for the Australian Brain Initiative von Carter, Adrian, Richards, Linda J., Apthorp, Deborah, Azghadi, Mostafa Rahimi, Badcock, David R., Balleine, Bernard, Bekkers, John M., Berk, Michael, Bourne, James A., Bradley, Andrew P., Breakspear, Michael, Brichta, Alan, Carter, Olivia, Castles, Anne, Chakli, Khaled, Cohen-Woods, Sarah, Conn, Simon J., Cornish, Jennifer, Cornish, Kim, de Zubicaray, Greg, Egan, Gary F., Enticott, Peter G., Fitzgibbon, Bernadette M., Forlini, Cynthia, Fornito, Alex, Griffiths, Lyn, Gullifer, Judith, Hall, Wayne, Halliday, Glenda, Hannan, Anthony J., Harrer, Stefan, Harvey, Alan, Hatherly, Chris, Hickie, Ian B., Kennett, Jeanette, Kiernan, Matthew, Kilpatrick, Trevor, Kiral-Kornek, Isabell, Korgaonkar, Mayuresh S., Lawrence, Andrew J., Leventer, Rick, Levy, Neil, Licinio, Julio, Lovell, Nigel, Mackellar, Geoff, Malcolm, Lynne, Mason, Alice, Mattingley, Jason B., Medland, Sarah E., Michie, Patricia T., Nithianantharajah, Jess, Parker, John, Payne, Jonathan M., Poole-Warren, Laura, Sah, Pankaj, Sarnyai, Zoltan, Schofield, Peter R., Shimoni, Olga, Shum, David H.K., Silk, Tim, Slee, Mark, Smith, Ashleigh E., Soulis, Tina, Sriram, Sharath, Stuart, Greg J., Tapson, Jonathan, Thompson, Matthew B., van Schaik, André, Vincent, Nicole A., Vissel, Bryce, Waters, Allison

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