When NRF2 talks, who's listening? von Wakabayashi, Nobunao, Slocum, Stephen L, Skoko, John J, Shin, Soona, Kensler, Thomas W

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Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms von Palliyaguru, Dushani L., Chartoumpekis, Dionysios V., Wakabayashi, Nobunao, Skoko, John J., Yagishita, Yoko, Singh, Shivendra V., Kensler, Thomas W.

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Keap1/Nrf2 pathway activation leads to a repressed hepatic gluconeogenic and lipogenic program in mice on a high-fat diet von Slocum, Stephen L., Skoko, John J., Wakabayashi, Nobunao, Aja, Susan, Yamamoto, Masayuki, Kensler, Thomas W., Chartoumpekis, Dionysios V.

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Peroxiredoxin Involvement in the Initiation and Progression of Human Cancer von Hampton, Mark B, Vick, Kate A, Skoko, John J, Neumann, Carola A

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Peroxiredoxin-1 Tyr194 phosphorylation regulates LOX-dependent extracellular matrix remodelling in breast cancer von Attaran, Shireen, Skoko, John J., Hopkins, Barbara L., Wright, Megan K., Wood, Laurel E., Asan, Alparslan, Woo, Hyun Ae, Feinberg, Adam, Neumann, Carola A.

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Notch-Nrf2 Axis: Regulation of Nrf2 Gene Expression and Cytoprotection by Notch Signaling von Wakabayashi, Nobunao, Skoko, John J., Chartoumpekis, Dionysios V., Kimura, Shoko, Slocum, Stephen L., Noda, Kentaro, Palliyaguru, Dushani L., Fujimuro, Masahiro, Boley, Patricia A., Tanaka, Yugo, Shigemura, Norihisa, Biswal, Shyam, Yamamoto, Masayuki, Kensler, Thomas W.

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Signals Getting Crossed in the Entanglement of Redox and Phosphorylation Pathways: Phosphorylation of Peroxiredoxin Proteins Sparks Cell Signaling von Skoko, John J, Attaran, Shireen, Neumann, Carola A

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The peroxidase PRDX1 inhibits the activated phenotype in mammary fibroblasts through regulating c-Jun N-terminal kinases von Jezierska-Drutel, Agnieszka, Attaran, Shireen, Hopkins, Barbara L, Skoko, John J, Rosenzweig, Steven A, Neumann, Carola A

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A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7 von Hopkins, Barbara L, Nadler, Monica, Skoko, John J, Bertomeu, Thierry, Pelosi, Andrea, Shafaei, Parisa Mousavi, Levine, Kevin, Schempf, Anja, Pennarun, Bodvael, Yang, Bo, Datta, Dipak, Bucur, Octavian, Ndebele, Kenneth, Oesterreich, Steffi, Yang, Da, Giulia Rizzo, Maria, Khosravi-Far, Roya, Neumann, Carola A

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A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells von Vogt, Andreas, McDonald, Peter R, Tamewitz, Aletheia, Sikorski, Rachel P, Wipf, Peter, Skoko, 3rd, John J, Lazo, John S

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Redox regulation of RAD51 Cys319 and homologous recombination by peroxiredoxin 1 von Skoko, John J., Cao, Juxiang, Gaboriau, David, Attar, Myriam, Asan, Alparslan, Hong, Lisa, Paulsen, Candice E., Ma, Hongqiang, Liu, Yang, Wu, Hanzhi, Harkness, Trey, Furdui, Cristina M., Manevich, Yefim, Morrison, Ciaran G., Brown, Erika T., Normolle, Daniel, Spies, Maria, Spies, Michael Ashley, Carroll, Kate, Neumann, Carola A.

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Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities von Vázquez Rivera, Alondra, Donald, Heather, Alaoui-El-Azher, Mounia, Skoko, John J, Lazo, John S, Parniak, Michael A, Johnston, Paul A, Sluis-Cremer, Nicolas

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Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity von Skoko, John J, Wakabayashi, Nobunao, Noda, Kentaro, Kimura, Shoko, Tobita, Kimimasa, Shigemura, Norihisa, Tsujita, Tadayuki, Yamamoto, Masayuki, Kensler, Thomas W

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Sulforaphane Diminishes the Formation of Mammary Tumors in Rats Exposed to 17β-Estradiol von Palliyaguru, Dushani L, Yang, Li, Chartoumpekis, Dionysios V, Wendell, Stacy G, Fazzari, Marco, Skoko, John J, Liao, Yong, Oesterreich, Steffi, Michalopoulos, George K, Kensler, Thomas W

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Electrophilic fatty acids impair RAD51 function and potentiate the effects of DNA-damaging agents on growth of triple-negative breast cells von Asan, Alparslan, Skoko, John J., Woodcock, Chen-Shan Chen, Wingert, Bentley M., Woodcock, Steven R., Normolle, Daniel, Huang, Yi, Stark, Jeremy M., Camacho, Carlos J., Freeman, Bruce A., Neumann, Carola A.

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Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies von Hong, Lisa, Braden, Dennis C., Zhao, Yaoning, Skoko, John J., Chang, Fei, Woodcock, Steven R., Uvalle, Crystall, Casey, Allison, Wood, Katherine, Salvatore, Sonia R., Asan, Alparslan, Harkness, Trey, Fagunloye, Adeola, Razzaghi, Mortezaali, Straub, Adam, Spies, Maria, Brown, Daniel D., Lee, Adrian V., Schopfer, Francisco, Freeman, Bruce A., Neumann, Carola A.

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The Benzo[c]phenanthridine Alkaloid, Sanguinarine, Is a Selective, Cell-active Inhibitor of Mitogen-activated Protein Kinase Phosphatase-1 von Vogt, Andreas, Tamewitz, Aletheia, Skoko, John, Sikorski, Rachel P., Giuliano, Kenneth A., Lazo, John S.

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Redox Regulation of Cdc25B by Cell-Active Quinolinediones von Brisson, Marni, Nguyen, Theresa, Wipf, Peter, Joo, Beomjun, Day, Billy W, Skoko, John S, Schreiber, Emanuel M, Foster, Caleb, Bansal, Pallavi, Lazo, John S

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Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B von Keinan, Shahar, Paquette, William D, Skoko, John J, Beratan, David N, Yang, Weitao, Shinde, Sunita, Johnston, Paul A, Lazo, John S, Wipf, Peter

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Development and optimization of high-throughput in vitro protein phosphatase screening assays von Lazo, John S, Tierno, Marni Brisson, Johnston, Paul A, Foster, Caleb, Skoko, John J, Shinde, Sunita N, Shun, Tong Ying

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