PPD04.02 First-Line Nivolumab + Ipilimumab (NIVO+IPI) in Metastatic NSCLC: 5-Year Survival in CheckMate 227 von Borghaei, H., Brahmer, J.R., Lee, J.-S., Ciuleanu, T.-E., Bernabe Caro, R., Nishio, M., Urban, L., Audigier-Valette, C., Lupinacci, L., Sangha, R., Paz-Ares, L.G., Reck, M., John O’Byrne, K., Gupta, R.G., Bushong, J., Li, L., Blum, S.I., Eccles, L., Ramalingam, S.S.

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Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM): a multicentre, single-arm, phase 2 trial with a safety run-in von Nowak, Anna K, Lesterhuis, W Joost, Kok, Peey-Sei, Brown, Chris, Hughes, Brett GM, Karikios, Deme J, John, Thomas, Kao, Steven C-H, Leslie, Connull, Cook, Alistair M, Pavlakis, Nick, Briscoe, Karen, O'Byrne, Kenneth J, Karapetis, Christos S, Lam, Wei-Sen, Langford, Ailsa, Yip, Sonia, Stockler, Martin R

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Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS)... von Treasure, Tom, Prof, Lang-Lazdunski, Loic, MD, Waller, David, FRCS [CTh], Bliss, Judith M, Prof, Tan, Carol, FRCS [CTh], Entwisle, James, FRCR, Snee, Michael, DM, O'Brien, Mary, MD, Thomas, Gill, FRCR, Senan, Suresh, Prof, O'Byrne, Ken, Prof, Kilburn, Lucy S, MSc, Spicer, James, MRCP, Landau, David, FRCR, Edwards, John, FRCS [CTh], Coombes, Gill, RGN, Darlison, Liz, RGN, Peto, Julian, Prof

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Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC von Ramalingam, Suresh S, Vansteenkiste, Johan, Planchard, David, Cho, Byoung Chul, Gray, Jhanelle E, Ohe, Yuichiro, Zhou, Caicun, Reungwetwattana, Thanyanan, Cheng, Ying, Chewaskulyong, Busyamas, Shah, Riyaz, Cobo, Manuel, Lee, Ki Hyeong, Cheema, Parneet, Tiseo, Marcello, John, Thomas, Lin, Meng-Chih, Imamura, Fumio, Kurata, Takayasu, Todd, Alexander, Hodge, Rachel, Saggese, Matilde, Rukazenkov, Yuri, Soria, Jean-Charles

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Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC von Socinski, Mark A, Jotte, Robert M, Cappuzzo, Federico, Orlandi, Francisco, Stroyakovskiy, Daniil, Nogami, Naoyuki, Rodríguez-Abreu, Delvys, Moro-Sibilot, Denis, Thomas, Christian A, Barlesi, Fabrice, Finley, Gene, Kelsch, Claudia, Lee, Anthony, Coleman, Shelley, Deng, Yu, Shen, Yijing, Kowanetz, Marcin, Lopez-Chavez, Ariel, Sandler, Alan, Reck, Martin

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An Evaluation of Tumor Oxygenation and Gene Expression in Patients with Early Stage Non–Small Cell Lung Cancers von LE, Quynh-Thu, CHEN, Eunice, MITCHELL, John D, RICHARDSON, Donna, O'BYRNE, Ken J, KOONG, Albert C, GIACCIA, Amato J, SALIM, Ali, HONGBIN CAO, KONG, Christina S, WHYTE, Richard, DONINGTON, Jessica, CANNON, Walter, WAKELEE, Heather, TIBSHIRANI, Robert

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Osimertinib in Untreated EGFR-Mutated Advanced Non–Small-Cell Lung Cancer von Soria, Jean-Charles, Ohe, Yuichiro, Vansteenkiste, Johan, Reungwetwattana, Thanyanan, Chewaskulyong, Busyamas, Lee, Ki Hyeong, Dechaphunkul, Arunee, Imamura, Fumio, Nogami, Naoyuki, Kurata, Takayasu, Okamoto, Isamu, Zhou, Caicun, Cho, Byoung Chul, Cheng, Ying, Cho, Eun Kyung, Voon, Pei Jye, Planchard, David, Su, Wu-Chou, Gray, Jhanelle E, Lee, Siow-Ming, Hodge, Rachel, Marotti, Marcelo, Rukazenkov, Yuri, Ramalingam, Suresh S

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Effect of intranasal corticosteroid treatment on allergen‐induced changes in group 2 innate lymphoid cells in allergic rhinitis with mild asthma von Xie, Yanqing, Ju, Xiaotian, Beaudin, Suzanne, Wiltshire, Lesley, Oliveria, John Paul, MacLean, Jonathan, Sommer, Doron D., Cusack, Ruth, Li, Olga, Banerjee, Prajna, Keith, Paul K., O'Byrne, Paul M., Bauer, Rebecca N., Staton, Tracy, Gauvreau, Gail M., Sehmi, Roma

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Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection von Adlam, David, Al-Hussaini, Abtehale, Bouajila, Sara, d’Escamard, Valentina, Huang, Siying, Margaritis, Marios, Nelson, Christopher P., Welch, Catherine A., Jeunemaitre, Xavier, Barnay, Pierre, Rioufol, Gilles, Range, Grégoire, Harbaoui, Brahim, Cayla, Guillaume, Champin, Stanislas, Saint-Etienne, Christophe, Marliere, Stéphanie, Karrillon, Gaëtan, Gerbay, Antoine, Houpe, David, Wong, Claire Mei Yi, Giannoulatou, Eleni, Sweeting, Michael, McGrath-Cadell, Lucy, Dunwoodie, Sally L., Harvey, Richard, Holloway, Cameron, Nikpay, Majid, Goel, Anuj, Won, Hong-Hee, Willenborg, Christina, Kanoni, Stavroula, Kyriakou, Theodosios, Nelson, Christopher P., Webb, Thomas R., Alver, Maris, Auro, Kirsi, Bjonnes, Andrew, Chasman, Daniel I., Franceschini, Nora, Gieger, Christian, Hwang, Shih-Jen, Kleber, Marcus E., Morrison, Alanna, Rose, Lynda M., Scholz, Markus, Smith, Albert V., Uitterlinden, Andre, Beutner, Frank, Gauguier, Dominique, Goodall, Alison H., Gottesman, Omri, Han, Bok-Ghee, Kessler, Thorsten, König, Inke R., Lannfelt, Lars, Lind, Lars, Lindgren, Cecilia M., Mallick, Nadeem H., Meitinger, Thomas, Morris, Andrew P., Nieminen, Markku S., Pedersen, Nancy L., Rasheed, Asif, Sinisalo, Juha, Trompet, Stella, Wang, Laiyuan, Boerwinkle, Eric, Demuth, Ilja, Epstein, Stephen E., Esko, Tõnu, Franco, Oscar H., Franzosi, Maria Grazia, Granger, Christopher B., Harris, Tamara B., Hofman, Albert, Ingelsson, Erik, Iribarren, Carlos, Jukema, J Wouter, Karhunen, Pekka J., Kim, Bong-Jo, Kooner, Jaspal S., Kullo, Iftikhar J., Palmer, Colin N., Perola, Markus, Ridker, Paul M., Ripatti, Samuli, Salomaa, Veikko, Seedorf, Udo, Stewart, Alexandre F., Stott, David J., Thiery, Joachim, Zalloua, Pierre A., Reilly, Muredach P., Clarke, Robert, Watkins, Hugh, Samani, Nilesh J., Farrall, Martin, Hayes, Sharonne N., Samani, Nilesh J.

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Prognostic value of TP53, KRAS and EGFR mutations in nonsmall cell lung cancer: the EUELC cohort von SCOCCIANTI, Chiara, VESIN, Aurélien, MARTEL, Ghislaine, OLIVIER, Magali, BRAMBILLA, Elisabeth, TIMSIT, Jean-François, TAVECCHIO, Luca, BRAMBILLA, Christian, FIELD, John K, HAINAUT, Pierre

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Allergen-Induced Increases in Interleukin-25 and Interleukin-25 Receptor Expression in Mature Eosinophils from Atopic Asthmatics von Tang, Wei, Smith, Steven G., Salter, Brittany, Oliveria, John Paul, Mitchell, Patrick, Nusca, Graeme M., Howie, Karen, Gauvreau, Gail M., O'Byrne, Paul M., Sehmi, Roma

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Blood and immune development in human fetal bone marrow and Down syndrome von Jardine, Laura, Webb, Simone, Goh, Issac, Quiroga Londoño, Mariana, Reynolds, Gary, Mather, Michael, Olabi, Bayanne, Stephenson, Emily, Botting, Rachel A., Horsfall, Dave, Engelbert, Justin, Maunder, Daniel, Mende, Nicole, Murnane, Caitlin, Dann, Emma, McGrath, Jim, King, Hamish, Kucinski, Iwo, Queen, Rachel, Carey, Christopher D., Shrubsole, Caroline, Poyner, Elizabeth, Acres, Meghan, Jones, Claire, Ness, Thomas, Coulthard, Rowen, Elliott, Natalina, O’Byrne, Sorcha, Haltalli, Myriam L. R., Lawrence, John E., Lisgo, Steven, Balogh, Petra, Meyer, Kerstin B., Prigmore, Elena, Ambridge, Kirsty, Jain, Mika Sarkin, Efremova, Mirjana, Pickard, Keir, Creasey, Thomas, Bacardit, Jaume, Henderson, Deborah, Coxhead, Jonathan, Filby, Andrew, Hussain, Rafiqul, Dixon, David, McDonald, David, Popescu, Dorin-Mirel, Kowalczyk, Monika S., Li, Bo, Ashenberg, Orr, Tabaka, Marcin, Dionne, Danielle, Tickle, Timothy L., Slyper, Michal, Rozenblatt-Rosen, Orit, Regev, Aviv, Behjati, Sam, Laurenti, Elisa, Wilson, Nicola K., Roy, Anindita, Göttgens, Berthold, Roberts, Irene, Teichmann, Sarah A., Haniffa, Muzlifah

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Identification of protective and ‘at risk’ HLA genotypes for the development of pseudotumours around metal-on-metal hip resurfacings: a case-control study von Sheridan, Gerard A., Hanlon, Michael, Welch-Phillips, Adanna, Spratt, Karen, Hagan, Richard, O'Byrne, John M., Kenny, Patrick J., Kurmis, Andrew P., Masri, Bassam A., Garbuz, Donald S., Hurson, Conor J.

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Elevating CDCA3 Levels Enhances Tyrosine Kinase Inhibitor Sensitivity in TKI-Resistant EGFR Mutant Non-Small-Cell Lung Cancer von Sahin, Katherine B., Shah, Esha T., Ferguson, Genevieve P., Molloy, Christopher, Kalita-de Croft, Priyakshi, Hayes, Sarah A., Hudson, Amanda, Colvin, Emily, Kamitakahara, Hannah, Harvie, Rozelle, Hasovits, Csilla, Khan, Tashbib, Duijf, Pascal H. G., Howell, Viive M., He, Yaowu, Bolderson, Emma, Hooper, John D., Lakhani, Sunil R., Richard, Derek J., O'Byrne, Kenneth J., Adams, Mark N.

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Phospho-Akt Expression Is Associated with a Favorable Outcome in Non–Small Cell Lung Cancer von SHAH, Amit, SWAIN, William A, RICHARDSON, Donna, EDWARDS, John, STEWART, Duncan J, RICHARDSON, Catherine M, SWINSON, Daniel E. B, PATEL, Dipika, JONES, J. Louise, O'BYRNE, Kenneth J

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Prehabilitation Before Anterior Cruciate Ligament Reconstruction von Shaarani, Shahril R., MD, O’Byrne, John, MCh, FRCS(Tr. & Orth), FFSEM, FFSEM(UK), Moran, Ray, MCh, FRCS(Tr. & Orth), FFSEM

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P2.10-01 ALKTERNATE: A Pilot Study Alternating Lorlatinib with Crizotinib in Patients with ALK+ NSCLC and ALK-inhibitor Resistance von Itchins, M., Liang, S., Brown, C., Barnes, T., Marx, G., Chin, V., Kao, S., Yip, P.Y., Mersiades, A.J., Nagrial, A., Bray, V., Peters, G., Parakh, S., John, T., Li, M., Li, B.T., McKay, M., Molloy, M., O'Byrne, K., Lee, C., Gill, A., Solomon, B.J., Pavlakis, N.

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DREAM3R: Durvalumab with chemotherapy as first-line treatment in advanced pleural mesothelioma—A phase 3 randomized trial von Forde, Patrick M., Nowak, Anna K., Kok, Peey-Sei, Brown, Chris, Sun, Zhuoxin, Anagnostou, Valsamo, O'Byrne, Kenneth John, Yip, Sonia, Cook, Alistair, Lesterhuis, Willem Joost, Hughes, Brett Gordon Maxwell, Pavlakis, Nick, Brahmer, Julie R., Kindler, Hedy L., Tsao, Anne S., Zauderer, Marjorie Glass, Ramalingam, Suresh S., Stockler, Martin R.

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Hip and Knee Section, Treatment, Two-Stage Exchange Spacer-Related: Proceedings of International Consensus on Orthopedic Infections von Abdel, Matthew P., Barreira, Pedro, Battenberg, Andrew, Berry, Daniel J., Blevins, Kier, Font-Vizcarra, Lluís, Frommelt, Lars, Goswami, Karan, Greiner, Justin, Janz, Viktor, Kendoff, D.O., Limberg, A.K., Manrique, Jorge, Moretti, Biagio, Murylev, Valeriy, O'Byrne, John, Petrie, Michael J., Porteous, Andrew, Saleri, Solmaz, Sandiford, Nemandra A., Sharma, Vishwas, Shubnyakov, Igor, Sporer, Scott, Squire, Matthew W., Stockley, Ian, Tibbo, M.E., Turgeon, Thomas, Varshneya, Ankit, Wellman, Samuel, Zahar, Akos

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Inhaled Reliever Therapies for Asthma: A Systematic Review and Meta-Analysis von Rayner, Daniel G, Ferri, Dario M, Guyatt, Gordon H, O’Byrne, Paul M, Brignardello-Petersen, Romina, Foroutan, Farid, Chipps, Bradley, Sumino, Kaharu, Perry, Tamara T, Nyenhuis, Sharmilee, Oppenheimer, John, Israel, Elliot, Hoyte, Flavia, Rivera-Spoljaric, Katherine, McCabe, Ellen, Rangel, Susana, Shade, Lindsay E, Press, Valerie G, Hall, Lisa, Sue-Wah-Sing, Dia, Melendez, Angel, Orr, Hilarry, Winders, Tonya, Gardner, Donna D, Przywara, Kathyrn, Rank, Matthew A, Bacharier, Leonard B, Mosnaim, Giselle, Chu, Derek K

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