The origin of protein interactions and allostery in colocalization von Kuriyan, John, Eisenberg, David

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A Structural Perspective on the Regulation of the Epidermal Growth Factor Receptor von Kovacs, Erika, Zorn, Julie Anne, Huang, Yongjian, Barros, Tiago, Kuriyan, John

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Molecular mechanisms in signal transduction at the membrane von Kuriyan, John, Groves, Jay T

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The Conformational Plasticity of Protein Kinases von Huse, Morgan, Kuriyan, John

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Cryo-EM structure of a dimeric B-Raf: 14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases von Kondo, Yasushi, Ognjenović, Jana, Banerjee, Saikat, Karandur, Deepti, Merk, Alan, Kulhanek, Kayla, Wong, Kathryn, Roose, Jeroen P., Subramaniam, Sriram, Kuriyan, John

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A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS von Huang, William Y. C., Alvarez, Steven, Kondo, Yasushi, Lee, Young Kwang, Chung, Jean K., Lam, Hiu Yue Monatrice, Biswas, Kabir H., Kuriyan, John, Groves, Jay T.

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Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane von Karandur, Deepti, Nawrotek, Agata, Kuriyan, John, Cherfils, Jacqueline

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An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor von Zhang, Xuewu, Gureasko, Jodi, Shen, Kui, Cole, Philip A., Kuriyan, John

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Structural basis and regulation of the reductive stress response von Manford, Andrew G., Mena, Elijah L., Shih, Karen Y., Gee, Christine L., McMinimy, Rachael, Martínez-González, Brenda, Sherriff, Rumi, Lew, Brandon, Zoltek, Madeline, Rodríguez-Pérez, Fernando, Woldesenbet, Makda, Kuriyan, John, Rape, Michael

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Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3 von Jura, Natalia, Shan, Yibing, Cao, Xiaoxian, Shaw, David E, Kuriyan, John

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Architecture and Membrane Interactions of the EGF Receptor von Arkhipov, Anton, Shan, Yibing, Das, Rahul, Endres, Nicholas F., Eastwood, Michael P., Wemmer, David E., Kuriyan, John, Shaw, David E.

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Crystal structure of the kinase domain of a receptor tyrosine kinase from a choanoflagellate, Monosiga brevicollis von Bajaj, Teena, Kuriyan, John, Gee, Christine L

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Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction von Simonetta, Kyle R., Taygerly, Joshua, Boyle, Kathleen, Basham, Stephen E., Padovani, Chris, Lou, Yan, Cummins, Thomas J., Yung, Stephanie L., von Soly, Szerenke Kiss, Kayser, Frank, Kuriyan, John, Rape, Michael, Cardozo, Mario, Gallop, Mark A., Bence, Neil F., Barsanti, Paul A., Saha, Anjanabha

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How a DNA Polymerase Clamp Loader Opens a Sliding Clamp von Kelch, Brian A., Makino, Debora L., O'Donnell, Mike, Kuriyan, John

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Conformational Coupling across the Plasma Membrane in Activation of the EGF Receptor von Endres, Nicholas F., Das, Rahul, Smith, Adam W., Arkhipov, Anton, Kovacs, Erika, Huang, Yongjian, Pelton, Jeffrey G., Shan, Yibing, Shaw, David E., Wemmer, David E., Groves, Jay T., Kuriyan, John

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Deep mutational analysis reveals functional trade-offs in the sequences of EGFR autophosphorylation sites von Cantor, Aaron J., Shah, Neel H., Kuriyan, John

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CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks von Cofsky, Joshua C, Karandur, Deepti, Huang, Carolyn J, Witte, Isaac P, Kuriyan, John, Doudna, Jennifer A

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Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization von Shan, Yibing, Eastwood, Michael P., Zhang, Xuewu, Kim, Eric T., Arkhipov, Anton, Dror, Ron O., Jumper, John, Kuriyan, John, Shaw, David E.

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A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor von Huang, Yongjian, Ognjenovic, Jana, Karandur, Deepti, Miller, Kate, Merk, Alan, Subramaniam, Sriram, Kuriyan, John

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Emerging concepts in the regulation of the EGF receptor and other receptor tyrosine kinases von Endres, Nicholas F., Barros, Tiago, Cantor, Aaron J., Kuriyan, John

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