A metabolic perspective on nitric oxide function in melanoma von Jimenez, John, Dubey, Parul, Carter, Bethany, Koomen, John M., Markowitz, Joseph

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Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury von Yurdagul, Arif, Subramanian, Manikandan, Wang, Xiaobo, Crown, Scott B., Ilkayeva, Olga R., Darville, Lancia, Kolluru, Gopi K., Rymond, Christina C., Gerlach, Brennan D., Zheng, Ze, Kuriakose, George, Kevil, Christopher G., Koomen, John M., Cleveland, John L., Muoio, Deborah M., Tabas, Ira

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Mapping the cancer surface proteome in search of target antigens for immunotherapy von Di Meo, Francesco, Kale, Brandon, Koomen, John M., Perna, Fabiana

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An immunoproteomic approach to characterize the CAR interactome and signalosome von Ramello, Maria C, Benzaïd, Ismahène, Kuenzi, Brent M, Lienlaf-Moreno, Maritza, Kandell, Wendy M, Santiago, Daniel N, Pabón-Saldaña, Mibel, Darville, Lancia, Fang, Bin, Rix, Uwe, Yoder, Sean, Berglund, Anders, Koomen, John M, Haura, Eric B, Abate-Daga, Daniel

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Single-cell Characterization of the Cellular Landscape of Acral Melanoma Identifies Novel Targets for Immunotherapy von Li, Jiannong, Smalley, Inna, Chen, Zhihua, Wu, Jheng-Yu, Phadke, Manali S, Teer, Jamie K, Nguyen, Thanh, Karreth, Florian A, Koomen, John M, Sarnaik, Amod A, Zager, Jonathan S, Khushalani, Nikhil I, Tarhini, Ahmad A, Sondak, Vernon K, Rodriguez, Paulo C, Messina, Jane L, Chen, Y Ann, Smalley, Keiran S M

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Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial von Creelan, Benjamin C., Wang, Chao, Teer, Jamie K., Toloza, Eric M., Yao, Jiqiang, Kim, Sungjune, Landin, Ana M., Mullinax, John E., Saller, James J., Saltos, Andreas N., Noyes, David R., Montoya, Leighann B., Curry, Wesley, Pilon-Thomas, Shari A., Chiappori, Alberto A., Tanvetyanon, Tawee, Kaye, Frederic J., Thompson, Zachary J., Yoder, Sean J., Fang, Bin, Koomen, John M., Sarnaik, Amod A., Chen, Dung-Tsa, Conejo-Garcia, Jose R., Haura, Eric B., Antonia, Scott J.

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Unification of de novo and acquired ibrutinib resistance in mantle cell lymphoma von Zhao, Xiaohong, Lwin, Tint, Silva, Ariosto, Shah, Bijal, Tao, Jiangchuan, Fang, Bin, Zhang, Liang, Fu, Kai, Bi, Chengfeng, Li, Jiannong, Jiang, Huijuan, Meads, Mark B., Jacobson, Timothy, Silva, Maria, Distler, Allison, Darville, Lancia, Zhang, Ling, Han, Ying, Rebatchouk, Dmitri, Di Liberto, Maurizio, Moscinski, Lynn C., Koomen, John M., Dalton, William S., Shain, Kenneth H., Wang, Michael, Sotomayor, Eduardo, Tao, Jianguo

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Metabolomics of primary cutaneous melanoma and matched adjacent extratumoral microenvironment von Taylor, Nicholas J, Gaynanova, Irina, Eschrich, Steven A, Welsh, Eric A, Garrett, Timothy J, Beecher, Chris, Sharma, Ritin, Koomen, John M, Smalley, Keiran S M, Messina, Jane L, Kanetsky, Peter A

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Macrophage-Derived Cholesterol Contributes to Therapeutic Resistance in Prostate Cancer von El-Kenawi, Asmaa, Dominguez-Viqueira, William, Liu, Min, Awasthi, Shivanshu, Abraham-Miranda, Julieta, Keske, Aysenur, Steiner, KayLee K, Noel, Leenil, Serna, Amparo N, Dhillon, Jasreman, Gillies, Robert J, Yu, Xiaoqing, Koomen, John M, Yamoah, Kosj, Gatenby, Robert A, Ruffell, Brian

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K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling von Yin, Qing, Han, Tao, Fang, Bin, Zhang, Guolin, Zhang, Chao, Roberts, Evan R., Izumi, Victoria, Zheng, Mengmeng, Jiang, Shulong, Yin, Xiu, Kim, Minjung, Cai, Jianfeng, Haura, Eric B., Koomen, John M., Smalley, Keiran S. M., Wan, Lixin

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PTEN Loss Confers BRAF Inhibitor Resistance to Melanoma Cells through the Suppression of BIM Expression von PARAISO, Kim H. T, YUN XIANG, RIBAS, Antoni, DALLA PALMA, Maurizia, NATHANSON, Katherine L, KOOMEN, John M, MESSINA, Jane L, SMALLEY, Keiran S. M, REBECCA, Vito W, ABEL, Ethan V, CHEN, Y. Ann, MUNKO, A. Cecilia, WOOD, Elizabeth, FEDORENKO, Inna V, SONDAK, Vernon K, ANDERSON, Alexander R. A

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Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells von Hamaidi, Imene, Zhang, Lin, Kim, Nayoung, Wang, Min-Hsuan, Iclozan, Cristina, Fang, Bin, Liu, Min, Koomen, John M., Berglund, Anders E., Yoder, Sean J., Yao, Jiqiang, Engelman, Robert W., Creelan, Ben C., Conejo-Garcia, Jose R., Antonia, Scott J., Mulé, James J., Kim, Sungjune

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HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy von Emmons, Michael F, Faião-Flores, Fernanda, Sharma, Ritin, Thapa, Ram, Messina, Jane L, Becker, Jurgen C, Schadendorf, Dirk, Seto, Edward, Sondak, Vernon K, Koomen, John M, Chen, Yian A, Lau, Eric K, Wan, Lixin, Licht, Jonathan D, Smalley, Keiran S M

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HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma von Faião-Flores, Fernanda, Emmons, Michael F, Durante, Michael A, Kinose, Fumi, Saha, Biswarup, Fang, Bin, Koomen, John M, Chellappan, Srikumar P, Maria-Engler, Silvya Stuchi, Rix, Uwe, Licht, Jonathan D, Harbour, J William, Smalley, Keiran S M

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H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes von Mahajan, Kiran, Fang, Bin, Koomen, John M, Mahajan, Nupam P

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IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells von Remsing Rix, Lily L, Sumi, Natalia J, Hu, Qianqian, Desai, Bina, Bryant, Annamarie T, Li, Xueli, Welsh, Eric A, Fang, Bin, Kinose, Fumi, Kuenzi, Brent M, Chen, Y Ann, Antonia, Scott J, Lovly, Christine M, Koomen, John M, Haura, Eric B, Marusyk, Andriy, Rix, Uwe

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Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane von Damaghi, Mehdi, Tafreshi, Narges K., Lloyd, Mark C., Sprung, Robert, Estrella, Veronica, Wojtkowiak, Jonathan W., Morse, David L., Koomen, John M., Bui, Marilyn M., Gatenby, Robert A, Gillies, Robert J

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Noncanonical EphA2 Signaling Is a Driver of Tumor-Endothelial Cell Interactions and Metastatic Dissemination in BRAF Inhibitor‒Resistant Melanoma von Zhang, Chao, Smalley, Inna, Emmons, Michael F., Sharma, Ritin, Izumi, Victoria, Messina, Jane, Koomen, John M., Pasquale, Elena B., Forsyth, Peter A., Smalley, Keiran S.M.

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Proteome-wide Profiling of Clinical PARP Inhibitors Reveals Compound-Specific Secondary Targets von Knezevic, Claire E., Wright, Gabriela, Remsing Rix, Lily L., Kim, Woosuk, Kuenzi, Brent M., Luo, Yunting, Watters, January M., Koomen, John M., Haura, Eric B., Monteiro, Alvaro N., Radu, Caius, Lawrence, Harshani R., Rix, Uwe

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Cdc45 limits replicon usage from a low density of preRCs in mammalian cells von Wong, Philip G, Winter, Sherry L, Zaika, Elena, Cao, Thinh V, Oguz, Umut, Koomen, John M, Hamlin, Joyce L, Alexandrow, Mark G

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